Nivolumab Txhaj Tshuaj

Zoo Siab

• Ua ntej tau txais nivolumab txhaj tshuaj,

Nivolumab txhaj tshuaj yog siv:

• nyob ib leeg lossis sib xyaw nrog ipilimumab (Yervoy) txhawm rau kho qee yam mob melanoma (hom mob qog nqaij hlav) tau kis mus rau lwm qhov ntawm lub cev lossis tsis tuaj yeem raug tshem tawm los ntawm kev phais mob,
• kho thiab tiv thaiv qhov rov qab los ntawm qee yam mob melanoma tom qab kev phais mob kom tshem tawm nws thiab txhua qhov cuam tshuam ntawm cov nqaij thiab cov qog ntshav,
• ua ke nrog ipilimumab (Yervoy) txhawm rau kho qee yam mob ntsws (tsis yog mob ntsws hauv lub ntsws tsawg; NSCLC) uas tau kis mus rau lwm qhov hauv lub cev,
• ua ke nrog ipilimumab (Yervoy) thiab kev kho mob platinum siv los kho qee yam ntawm NSCLC uas tau rov qab los lossis tau kis mus rau lwm qhov ntawm lub cev,
• nyob ib leeg txhawm rau kho qee yam ntawm NSCLC uas tau kis mus rau lwm qhov ntawm lub cev thiab tau muaj kev tsis zoo ntau thaum lub sijhawm lossis tom qab kho cov tshuaj khomob platinum,
• los kho lwm hom mob ntsws ntsws (me me ntawm cov ntsws mob ntsws cancer, SCLC) uas tau kis mus rau lwm qhov ntawm lub cev uas muaj kev phom sij tom qab kev kho mob tom qab platinum chemotherapy thiab nrog tsawg kawg ib qho kev siv tshuaj kho mob,
• txhawm rau kho kab mob hauv lub raum lub siab ntev (RCC, ib hom mob qog nqaij hlav uas pib nyob rau hauv lub hlwb ntawm ob lub raum) uas muaj qhov tsis zoo tom qab kev kho mob nrog lwm cov tshuaj kho mob,
• ua ke nrog ipilimumab (Yervoy) los kho RCC siab heev hauv cov neeg uas tsis tau kho nrog lwm cov tshuaj kho mob,
• los kho Hodgkin's lymphoma (Hodgkin's disease) hauv cov neeg laus uas tau ua kom tsis zoo lossis tsis teb rau lub cev kev hloov pauv ntawm tes (cov txheej txheem uas qee cov ntshav tawm ntawm lub cev tawm thiab tom qab ntawd rov los rau hauv lub cev tom qab kev kho mob thiab / lossis kev kho hluav taws xob) thiab brentuximab vedotin (Adcetris) kev kho mob lossis tsawg kawg peb yam kev khomob suav nrog kev hloov qia hauv hlwb,
• txhawm rau kho qee yam mob taub hau thiab caj dab uas ua rau rov qab los yog uas tau kis mus rau lwm qhov ntawm lub cev lossis mob tsis zoo thaum lub sijhawm lossis tom qab kho nrog lwm cov tshuaj kho mob,
• los kho mob urothelial mob cancer (mob qog ntawm lub zais zis thiab lwm qhov ntawm lub zais zis) uas tau kis mus rau lwm qhov ntawm lub cev thiab muaj kev phom sij ntau ntxiv thaum lossis tom qab kho nrog lwm cov tshuaj kho mob,
• nyob ib leeg lossis sib xyaw nrog ipilimumab los kho hom mob qog nqaij hlav cancer (mob cancer uas pib hauv cov hnyuv loj) hauv cov neeg laus thiab menyuam hnub nyoog 12 xyoos thiab laus dua uas tau kis mus rau lwm qhov ntawm lub cev thiab tau mob loj dua tom qab kho nrog lwm yam kev kho mob tshuaj,
• ib leeg lossis hauv kev sib xyaw nrog ipilimumab los kho tus mob hepatocellular carcinoma (HCC; ib hom mob qog nqaij hlav cancer) hauv cov neeg uas tau kho yav tas los nrog sorafenib (Nexafar),
• los kho tus mob esophageal squamous cell mob cancer (mob cancer ntawm lub raj uas txuas koj lub caj pas rau koj lub plab) uas tau kis mus rau lwm qhov ntawm lub cev, tau mob hnyav dua tom qab kev kho mob nrog lwm cov tshuaj kho mob, lossis tsis tuaj yeem kho nrog kev phais mob,
• thiab ua ke nrog ipilimumab los kho tus mob malignant pleural mesothelioma (hom mob cancer uas cuam tshuam rau sab hauv lub ntsws thiab lub hauv siab) cov laus tsis tuaj yeem tshem tawm los ntawm kev phais mob.

Nivolumab nyob rau hauv chav kawm ntawm cov tshuaj hu ua monoclonal antibodies. Nws ua haujlwm los ntawm kev pab koj lub cev tiv thaiv kabmob ua rau qeeb lossis nres kev loj hlob ntawm cov qog nqaij hlav cancer.

Nivolumab los ua kua yuav tau txhaj rau txoj hlab ntshav li 30 feeb los ntawm kws kho mob lossis kws saib xyuas mob hauv tsev kho mob lossis chaw kho mob. Thaum nivolumab tau muab rau ib leeg los kho tus mob melanoma, mob qog nqaij hlav hauv hlwb tsawg (NSCLC), Hodgkin lymphoma, mob taub hau thiab caj dab, mob cancer urothelial, RCC siab heev, mob qog nqaij hlav cancer, esophageal squamous cell mob cancer, lossis hepatocellular carcinoma, feem ntau yog muab ib zaug txhua txhua 2 lossis 4 lub lim tiam nyob ntawm koj noj ntau npaum li koj tus kws kho mob pom zoo kom koj tau txais kev kho mob. Thaum nivolumab raug muab rau ib leeg los kho mob qog nqaij hlav cancer me me (SCLC), feem ntau yog muab rau txhua 2 lis piam ib zaug ntev npaum li kws kho mob pom zoo kom koj tau txais kev kho mob. Thaum nivolumab tau muab nrog ipilimumab los kho tus mob melanoma, hepatocellular carcinoma, mob caj dab, lossis mob RCC, feem ntau yog muab ib zaug txhua 3 asthiv rau 4 koob tshuaj nrog ipilimumab, thiab tom qab ntawd ib leeg ib zaug txhua 2 lossis 4 lub lis piam nyob ntawm koj ntau npaum li cas rau tsuav koj tus kws kho mob pom zoo kom koj tau txais kev kho mob. Thaum nivolumab raug muab nrog ipilimumab los kho NSCLC, feem ntau yog muab ib zaug txhua 2 lub lis piam ntev npaum li koj tus kws kho mob pom zoo kom koj tau txais kev kho mob. Thaum nivolumab raug muab nrog ipilimumab los kho tus mob malignant pleural mesothelioma, feem ntau yog muab ib zaug txhua 3 asthiv mus ntev npaum li koj tus kws kho mob pom zoo kom koj tau txais kev kho mob. Thaum nivolumab raug muab nrog cov tshuaj ipilimumab thiab platinum kho mob los kho NSCLC, feem ntau yog muab ib zaug txhua 3 asthiv ntev npaum li koj tus kws kho mob pom zoo kom koj tau txais kev kho mob.

Nivolumab tuaj yeem ua rau mob hnyav lossis tuag taus thaum lub sijhawm hla ntshav. Tus kws kho mob lossis tus nais maum yuav saib xyuas koj kom zoo thaum koj tau txais kev lis ntshav thiab tsis ntev tom qab Txoj kev lis ntshav ntawd kom paub tseeb tias koj tsis muaj qhov kev txhaum dab tsi rau cov tshuaj. Qhia rau koj tus kws kho mob lossis tus kws saib xyuas neeg mob tam sim ntawd yog tias koj pom muaj cov tsos mob tshwm sim thaum lub sijhawm nqus: ua daus no lossis tshee, khaus, tawm pob, ua xua, ua pa nyuaj, kiv taub hau, ua npaws, thiab tsaus muag.

Koj tus kws kho mob tuaj yeem txo koj txoj kev noj qab haus huv, ncua nws, lossis nres koj cov kev txhaj tshuaj nivolumab, lossis kho koj nrog cov tshuaj ntxiv nyob ntawm koj cov lus teb rau cov tshuaj thiab cov kev mob tshwm sim uas koj tau ntsib dua. Tham nrog koj tus kws kho mob txog saib koj xav li cas thaum kho koj tus mob.

Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia txog cov neeg mob rau koj (Kev Qhia Tshuaj Kho Mob) thaum koj pib kho nrog nivolumab txhaj tshuaj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej tau txais nivolumab txhaj tshuaj,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau nivolumab, lwm yam tshuaj noj, lossis ib qho twg hauv kev txhaj tshuaj nivolumab. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia rau koj tus kws kho mob yog tias koj tau hloov khoom nruab nrog cev. Kuj qhia koj tus kws kho mob yog tias koj tau lossis muaj dua lub sijhawm ua haujlwm autoimmune (mob lub cev tiv thaiv kab mob hauv lub cev muaj kev noj qab haus huv) xws li Crohn's mob (mob uas lub nruab zog tua cov kab mob ntawm lub plab ua rau mob, raws plab, poob phaus, thiab kub taub hau), mob ncauj plab (mob uas ua rau o thiab ua mob rau sab hauv txoj hnyuv [txoj hnyuv loj thiab lub qhov quav), lossis mob lupus (mob uas cov kabmob tiv thaiv ntau cov nqaij thiab kabmob nrog rau daim tawv nqaij, pob qij txha, ntshav, thiab raum); ib yam kab mob ntsws lossis ua pa nyuaj; lossis lub qog, mob raum lossis mob siab.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Koj yuav tsum tau kuaj cev xeeb tub ua ntej koj tau txais nivolumab. Koj yuav tsum tsis txhob cev xeeb tub thaum koj tau txhaj tshuaj nivolumab. Koj yuav tsum siv kev tswj kom tsis txhob muaj menyuam kom tiv thaiv kev xeeb tub thaum koj kho nrog nivolumab txhaj tshuaj thiab tsawg kawg 5 hlis tom qab koj koob kawg. Tham nrog koj tus kws kho mob txog kev tiv thaiv kev xeeb tub uas yuav ua haujlwm rau koj. Yog tias koj xeeb tub thaum koj tau txhaj tshuaj nivolumab, hu rau koj tus kws kho mob tam sim ntawd. Kev txhaj tshuaj Nivolumab tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab.
• qhia rau koj tus kws kho mob yog tias koj pub mis niam lossis npaj yuav pub mis. Koj yuav tsum tsis txhob pub niam mis thaum tau txais kev txhaj tshuaj nivolumab thiab rau 5 lub hlis tom qab koj zaum kawg.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Yog tias koj ncua sij hawm txhawm rau txhaj tshuaj nivolumab, hu rau koj tus kws kho mob sai li sai tau.

Nivolumab txhaj tshuaj tuaj yeem tsim cov kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• txha, nraub qaum, puab tsaig, lossis mob pob txha
• mob leeg los yog tsis muaj zog
• qhuav, tawg, nti tawv nqaij
• liab, o, lossis mob rau ntawm xib teg ntawm koj txhais tes lossis lub hauv qab ntawm koj txhais taw
• qhov ncauj tawm
• qhov muag qhuav los yog qhov ncauj

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv nqe CAS, qhia rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:

• txog siav
• tshiab lossis txhawm rau hnoos
• hnoos tau ntshav
• mob hauv siab
• zawv plab
• tsam mob hauv plab lossis mob siab
• cov quav uas yog xim dub, tarry, nplaum, lossis muaj ntshav
• nkees lossis qaug zog
• hnov txias
• tob hauv lub suab lossis txhaws qa
• hloov hauv qhov hnyav (nce lossis poob)
• hloov hauv lub siab lossis tus cwj pwm (txo tus txiv neej tsav tsheb, txob taus, lossis hnov ​​qab)
• caj dab txhav txhav
• mob, kub hnyiab, tingling, lossis loog hauv txhais tes lossis taw
• mob taub hau, suav nrog cov uas tsis txawv lossis yuav tsis ploj
• hnov (pom tej yam lossis hnov ​​cov suab uas tsis muaj nyob)
• qaug dab peg
• tsis meej pem
• ua npaws
• plaub hau poob
• khaus, tawm pob, ua xua lossis ua hlwv ntawm koj cov tawv nqaij
• cem quav
• xeev siab
• ntuav
• tsaug zog
• kiv tob hau lossis tsaus muag
• daj tawv nqaij lossis qhov muag, tso zis muaj xim dub, los ntshav los yog ua pob yooj yim dua li ib txwm, tsis qab los noj mov, tsis muaj zog, lossis mob ntawm sab xis ntawm lub plab.
• nce nqhis dej
• txo qis lossis nce tso zis
• o ntawm lub ntsej muag, caj npab, ceg, ko taw lossis pob taws
• ntshav hauv zis
• kev hloov pauv ntawm lub zeem muag
• kev ua pa uas hnov ​​tsw tsw qab

Nivolumab txhaj tshuaj tuaj yeem ua lwm cov phiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum tau txais cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau kev txhaj tshuaj nivolumab. Rau qee qhov xwm txheej, koj tus kws kho mob yuav xaj kuaj sim ua ntej koj pib kho kom paub seb koj puas muaj peev xwm kho tau tus mob nivolumab.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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