Kev Tshuaj Ntsuam Kev Tshawb Fawb PTEN

Zoo Siab

• PTEN caj ces kuaj tau yog dab tsi?
• Nws siv rau dab tsi?
• Vim li cas kuv thiaj xav tau txoj kev tshuaj ntsuam genetic PTEN?
• Muaj dab tsi tshwm sim thaum kuaj ntshav PTEN?
• Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?
• Puas muaj kev pheej hmoo rau kev kuaj?
• Cov txiaj ntsig li cas?
• Puas muaj lwm yam ntxiv uas kuv xav paub txog kev kuaj ntsuas ntawm PTEN?
• Ua tim khawv

PTEN caj ces kuaj tau yog dab tsi?

Kev kuaj ntsuas keeb ntawm PTEN saib rau kev hloov pauv, paub tias hloov pauv, hauv tus gene hu ua PTEN. Cov noob yog qhov tseem ceeb ntawm caj ces dhau los ntawm koj niam thiab koj txiv.

Lub cev PTEN pab nres qhov kev loj hlob ntawm cov qog. Nws lub npe hu ua cov tshuaj tiv thaiv qog. Lub qog nqaij hlav hlav hlav zoo li tus nres ntawm lub tsheb. Nws tso "tus tsuj" rau ntawm lub hlwb, yog li lawv tsis faib ceev nrawm. Yog tias koj muaj PTEN caj ces hloov, nws tuaj yeem ua rau kev loj hlob ntawm cov qog hlav tsis tuaj yeem hu ua hamartomas. Hamartomas tuaj yeem tshwm thoob plaws lub cev. Qhov hloov tau tuaj yeem tuaj yeem ua rau kev loj hlob ntawm qog hlav qog ntshav.

PTEN kev hloov caj ces tuaj yeem tau los ntawm koj niam koj txiv, lossis tau txais tom qab hauv lub neej los ntawm ib puag ncig lossis los ntawm kev ua yuam kev uas tshwm sim hauv koj lub cev thaum faib cov cell.

Kev hloov pauv ntawm PTEN hloov pauv tuaj yeem ua rau muaj ntau yam kev mob tsis zoo. Qee qhov no tuaj yeem pib thaum tseem yau lossis thaum yau. Lwm qhov tshwm sim thaum laus. Cov kev tsis zoo no feem ntau tau koom ua ke thiab hu ua PTEN hamartoma syndrome (PTHS) thiab suav nrog:

• Cov leeg Cowden, ib qho kev tsis sib haum xeeb uas ua rau ntau txoj kev loj hlob ntawm hamartomas thiab ua rau muaj kev pheej hmoo ntawm ntau hom mob cancer, nrog rau mob qog mis, mis, lub qog, thiab mob hnyuv. Cov neeg muaj tus mob Cowden syndrome feem ntau muaj qhov loj dua lub taub hau loj (loj dua me me), kev loj hlob qeeb, thiab / lossis mob vwm.
• Cov tsos mob Bannayan-Riley-Ruvalcaba kuj ua rau hamartomas thiab macrocephaly. Ib qho ntxiv, cov neeg muaj tus mob no yuav muaj kev tsis taus kawm thiab / lossis muaj mob vwm. Cov txiv neej nrog qhov tsis sib haum xeeb feem ntau muaj qhov tsaus nti ntawm tus qau.
• Proteus lossis Proteus-zoo li mob ntsws tuaj yeem ua rau mob hla ntawm cov pob txha, tawv nqaij, thiab lwm cov ntaub so ntswg, nrog rau hamartomas thiab macrocephaly.

Tau txais (tseem hu ua somatic) PTEN kev hloov caj ces yog ib qho pom muaj ntau tshwm sim hauv tib neeg mob cancer. Cov kev hloov tshwm sim tau pom muaj ntau hom mob qog nqaij hlav, suav nrog mob cancer prostate, mob cancer ntawm lub tsev menyuam, thiab qee cov qog hlwb.

Lwm lub npe: PTEN gene, cov noob tshuaj ntsuam tag nrho; PTEN ua ntu zus thiab rho tawm / duplication

Nws siv rau dab tsi?

Kev ntsuam xyuas yog siv los nrhiav PTEN kev hloov caj dab. Nws tsis yog qhov kev ntsuam xyuas niaj hnub. Feem ntau nws tau muab rau cov tib neeg raws li tsev neeg keeb kwm, cov tsos mob, lossis yav dhau los kuaj mob qog noj ntshav, tshwj xeeb tshaj yog mob cancer ntawm lub mis, thyroid, lossis uterus.

Vim li cas kuv thiaj xav tau txoj kev tshuaj ntsuam genetic PTEN?

Koj lossis koj tus menyuam yuav xav tau kev kuaj keeb kwm ntawm PTEN yog tias koj muaj tsev neeg muaj keeb kwm ntawm PTEN hloov caj ces thiab / lossis ib lossis ntau yam ntawm cov xwm txheej lossis cov tsos mob no:

• Ntau cov nqaij hamartomas, tshwj xeeb tshaj yog nyob hauv thaj chaw ua haujlwm hauv plab
• Macrocephaly (loj dua li lub taub hau loj dua)
• Kev loj hlob qeeb
• Cuam Tshuam
• Kev tsaus nti quav ntawm tus qau ua rau txiv neej
• Tus mob cancer mis
• Mob qog noj ntshav
• Uterine cancer hauv cov pojniam

Yog tias koj tau txheeb pom tias koj muaj mob qog noj ntshav thiab tsis muaj keeb kwm kab mob ntawm tsev neeg, koj tus kws kho mob yuav xaj kom kuaj xyuas no seb seb PTEN caj ces yug yuav ua rau koj mob cancer. Paub seb koj puas muaj kev hloov pauv tuaj yeem pab koj tus kws kho mob kwv yees saib koj tus kab mob yuav loj tuaj li cas thiab coj kev kho koj li cas.

Muaj dab tsi tshwm sim thaum kuaj ntshav PTEN?

Kev kuaj ntshav PTEN feem ntau yog kuaj ntshav. Lub sijhawm kuaj ntshav, tus kws saib xyuas kev noj qab haus huv yuav nqa ntshav los ntawm txoj hlab ntshav hauv koj txhais caj npab, siv rab koob me me. Tom qab cov koob raug tso nkag, cov ntshav me me yuav raug sau rau hauv lub khob kuaj lossis vial. Koj tuaj yeem hnov ​​me ntsis thaum cov koob nkag mus lossis tawm. Qhov no feem ntau yuav siv sijhawm tsawg dua tsib feeb.

Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?

Feem ntau koj tsis tas yuav muaj ib qho kev npaj tshwj xeeb rau ib qho kev ntsuas PTEN.

Puas muaj kev pheej hmoo rau kev kuaj?

Txoj kev kuaj ntshav muaj feem me me. Koj yuav muaj mob me lossis doog ntshav ntawm qhov chaw tso rab koob, tab sis feem ntau cov tsos mob ploj mus sai.

Cov txiaj ntsig li cas?

Yog tias koj cov txiaj ntsig pom tau tias koj muaj PTEN caj ces hloov, nws tsis txhais tau tias koj muaj mob qog nqaij hlav, tab sis koj qhov kev pheej hmoo siab dua coob leej neeg. Tab sis kev kuaj mob qog noj ntshav ntau dua tuaj yeem txo koj txoj kev pheej hmoo. Kab mob khees xaws raug kho ntau dua thaum pom thaum ntxov. Yog tias koj muaj lub cev hloov, koj tus kws kho mob yuav hais kom ib lossis ob peb yam ntawm cov kev tshuaj ntsuam nram no:

• Kev kuaj mob hnyuv, pib thaum hnub nyoog 35-40
• Mammogram, pib txij hnub nyoog 30 rau cov poj niam
• Kev ntsuas tus kheej lub mis ib hlis rau cov pojniam
• Kev ntsuas ntsuas pojniam txhua xyoo rau cov poj niam
• Kev kuaj cov thyroid txhua xyoo
• Kev kuaj xyuas daim tawv nqaij txhua xyoo rau kev loj hlob
• Kev kuaj raum txhua xyoo

Txhua xyoo cov thyroid thiab kuaj daim tawv nqaij tseem pom zoo rau cov menyuam yaus uas muaj PTEN hloov caj ces.

Kawm paub ntau ntxiv txog cov kev sim hauv chaw soj ntsuam, cov chaw siv ntsuas, thiab nkag siab cov txiaj ntsig tau.

Puas muaj lwm yam ntxiv uas kuv xav paub txog kev kuaj ntsuas ntawm PTEN?

Yog tias koj tau kuaj pom nrog PTEN kev hloov caj ces lossis xav txog kev sim, nws yuav pab tau hais lus rau tus kws sab laj tswv yim. Tus kws pab tswv yim txog caj ces yog tus kws tshaj lij kawm tiav los ntawm kev tshawb fawb caj ces thiab kev tshuaj ntsuam caj ces. Yog koj tseem tsis tau raug sim, tus kws pab tswv yim tuaj yeem pab koj nkag siab txog cov kev pheej hmoo thiab cov txiaj ntsig ntawm kev xeem. Yog tias koj tau sim koj, tus kws pab tswv yim tuaj yeem pab koj nkag siab qhov txiaj ntsig thiab coj koj mus txhawb cov kev pabcuam thiab lwm yam kev pabcuam.

Ua tim khawv

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Cov ntaub ntawv ntawm lub xaib no yuav tsum tsis txhob siv los hloov chaw kho mob lossis tswv yim kho mob. Hu rau kws kho mob yog tias koj muaj lus nug txog koj txoj kev noj qab haus huv.