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Hnub Kev Tsim: 21 Lub Xya Hli Ntuj 2021
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Congenital Hypothyroidism | causes , clinical features , screening , management | Endocrinology CH#1
Daim Duab: Congenital Hypothyroidism | causes , clinical features , screening , management | Endocrinology CH#1

Neonatal hypothyroidism yog qhov tsawg dua cov thyroid hormone ntau lawm hauv cov menyuam mos. Hauv qee qhov tsis tshua muaj tshwm sim, tsis muaj cov thyroid hormones txaus los ua. Tus mob no tseem hu ua Congenital hypothyroidism. Congenital txhais tau tam sim no txij thaum yug los.

Cov thyroid caj pas yog ib qho tseem ceeb ntawm cov kab mob endocrine. Nws yog nyob ntawm sab xub ntiag ntawm lub caj dab, tsuas yog saum toj no qhov chaw uas cov pob zeb ci tau sib ntsib. Cov thyroid ua rau cov tshuaj hormones uas tswj xyuas txhua txoj kev ntawm tes hauv lub cev siv lub zog. Tus txheej txheem no hu ua kev hloov khoom siv metabolism.

Mob Hypothyroidism hauv menyuam mos tej zaum yuav yog los ntawm:

  • Ib qho ploj los sis tsis zoo tsim cov thyroid caj pas
  • Lub caj pas pituitary uas tsis ua rau lub qog ua haujlwm lub qog
  • Cov thyroid hormones txaus ua tsis zoo lossis tsis ua haujlwm
  • Cov tshuaj uas leej niam coj thaum cev xeeb tub
  • Tsis muaj iodine nyob rau hauv leej niam txoj kev noj haus thaum cev xeeb tub
  • Cov tshuaj tua kab mob los ntawm leej niam lub cev uas thaiv tus menyuam cov thyroid txoj haujlwm

Lub qog ua haujlwm lub qog ua tsis tau tsim kho yog qhov feem ntau qhov teeb meem. Cov ntxhais cuam tshuam ob zaug ntau npaum li cov tub.


Feem ntau cov menyuam mos cuam tshuam muaj ob peb lossis tsis muaj mob. Qhov no yog vim tias lawv qib qog cov tshuaj hormones tsuas yog qis me ntsis xwb. Cov menyuam mos uas mob hypothyroidism heev feem ntau muaj cov yam ntxwv tshwj xeeb, suav nrog:

  • Npub saib
  • Puffy ntsej muag
  • Tuab nplaig uas nplaum tawm

Cov tsos no feem ntau loj hlob zuj zus tuaj thaum tus kab mob zuj zus tuaj.

Tej zaum tus menyuam no yuav muaj:

  • Pluag mov noj, txhawm chim ntu
  • Cem quav
  • Qhuav, brittle plaub hau
  • Hnyav quaj
  • Jaundice (tawv nqaij thiab tawv dawb ntawm lub qhov muag daj)
  • Tsis muaj cov leeg leeg (muag me me)
  • Tsis tshua muaj kab plaub hau
  • Qhov siab luv
  • Koj tsaug zog tsaug zog
  • Kev npam

Kev kuaj mob lub cev ntawm tus menyuam yuav qhia tau tias:

  • Kev txo qhov nqaij leeg
  • Kev loj hlob qeeb
  • Hub-suab quaj lossis lub suab
  • Luv tes thiab txhais ceg
  • Tej qhov mos mos loj heev rau ntawm pob txha taub hau (fontanelles)
  • Dav dav tes nrog tus ntiv tes luv
  • Cov pob txha dav dav sib cais

Kev kuaj ntshav yog ua tiav los kuaj cov thyroid muaj nuj nqi. Lwm yam kev ntsuam xyuas yuav suav nrog:


  • Cov thyroid ultrasound scan
  • Xoo hluav taws xob ntawm cov pob txha ntev

Kev paub thaum ntxov yog ib qho tseem ceeb heev. Feem ntau ntawm cov teebmeem ntawm hypothyroidism yog yooj yim thim rov qab. Vim li no, feem ntau lub xeev Asmeskas xav kom txhua tus menyuam yug tshiab yuav tsum raug kuaj kuaj hypothyroidism.

Thyroxine feem ntau yog muab rau kho hypothyroidism. Thaum tus menyuam pib noj cov tshuaj no, kuaj ntshav tas li kom ntseeg tau tias cov thyroid hormones txaus yog li ib txwm.

Txoj kev kuaj mob ntxov ib txwm ua rau kom muaj txiaj ntsig zoo. Cov menyuam mos liab tau kuaj pom thiab kho nyob rau thawj lub hlis lossis ntau zaus feem ntau muaj cov kev ntse.

Yog tsis kho mob me ntsis hypothyroidism tuaj yeem ua rau lub hlwb tsis ua haujlwm loj thiab muaj teeb meem kev loj hlob. Lub paj hlwb dhau ntawm txoj kev loj hlob tseem ceeb thaum thawj ob peb lub hlis tom qab yug. Tsis muaj cov thyroid hormones txaus tuaj yeem tsim kev puas tsuaj uas tsis tuaj yeem thim rov qab.

Hu koj tus kws kho mob yog hais tias:

  • Koj hnov ​​koj cov minyuam mos cov cim qhia pom lossis cov tsos mob ntawm hypothyroidism
  • Koj cev xeeb tub thiab tau dhau los ua cov tshuaj antithyroid lossis cov txheej txheem

Yog tias tus poj niam cev xeeb tub noj tshuaj radioactive iodine rau mob qog noj ntshav, cov thyroid caj pas yuav raug puas tsuaj nyob hauv kev mob plab hauv plab. Cov menyuam mos uas lawv niam noj cov tshuaj no yuav tsum tau ua tib zoo saib tomqab yug los rau cov tsos mob ntawm hypothyroidism. Tsis tas li, cov poj niam cev xeeb tub yuav tsum tsis txhob tseg ntsev ntsev iodine ntxiv.


Feem ntau lub xeev xav kom muaj kev soj ntsuam cov niaj zaus los kuaj xyuas txhua tus menyuam mos rau lub sijhawm hypothyroidism. Yog tias koj lub xeev tsis muaj qhov yuav tsum tau ua no, nug koj tus kws kho mob yog tias koj tus menyuam tshiab yuav tsum raug txheeb xyuas.

Cretinism; Congenital hypothyroidism Cov Neeg Mob Hlob

Chuang J, Gutmark-Me I, Rose SR. Lub qog mob nyob rau hauv cov leeg neonate. Hauv: Martin RJ, Fanaroff AA, Walsh MC, eds. Fanaroff thiab Martin's Neonatal-Perinatal Tshuaj: Cov kab mob ntawm lub plab thiab menyuam mosCov. 10 tus ed. Philadelphia, PA: Elsevier Saunders; Xyoo 2015: chap 97.

Wassner AJ, Smith JR. Kev Hypothyroidism. Hauv: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Phau Ntawv ntawm PediatricsCov. 21st ed. Philadelphia, PA: Elsevier; 2020: chap 581.

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