Dermatomyositis

Dermatomyositis yog ib hom mob leeg mob uas cuam tshuam rau kev o thiab nqaij tawv. Polymyositis yog ib qho kev mob zoo sib xws, uas tseem cuam tshuam rau cov leeg tsis muaj zog, o, mob thiab nqaij tawv tab sis tsis muaj pob khaus tawv. Ob qho tib si yog ib feem ntawm pawg neeg loj dua ntawm cov kab mob hu ua inflammatory myopathy.

Ua kom mob dermatomyositis tsis paub meej. Cov kws tshaj lij xav tias nws yuav yog kis tau kis kab mob ntawm cov leeg los yog teeb meem nrog lub cev tiv thaiv kab mob. Nws kuj tseem yuav tshwm sim rau cov neeg uas muaj mob qog noj ntshav hauv plab, ntsws, lossis lwm qhov hauv lub cev.

Txhua tus neeg tuaj yeem kho tus mob no. Feem ntau nws tshwm sim rau cov menyuam yaus hnub nyoog 5 txog 15 thiab cov laus hnub nyoog 40 txog 60. Nws cuam tshuam rau cov poj niam ntau dua li cov txiv neej.

Cov tsos mob tuaj yeem suav nrog:

• Mob leeg tsis muaj zog, ua pob txha, lossis mob mob
• Cov teeb meem nqos
• Ntshav xim rau cov tawv muag sab saud
• Cov tawv nqaij liab-liab ua pob
• Ua tsis taus pa

Cov leeg tsis muaj zog lub zog tuaj yeem cia li nco dheev lossis pib qeeb qeeb nyob rau lub lim tiam lossis ntau hli. Koj yuav muaj teeb meem tsa caj npab hla koj lub taub hau, sawv ntawm qhov chaw zaum, thiab nce ntaiv.

Cov pob tshwm tuaj yeem tshwm sim ntawm koj lub ntsej muag, ntsej muag, caj dab, xub pwg, sab sauv, thiab sab nraub qaum.

Tus kws kho mob yuav kuaj xyuas lub cev. Kev ntsuam xyuas yuav muaj xws li:

• Ntshav mus kuaj xyuas cov qib ntawm cov leeg ntshav hu ua creatine phosphokinase thiab aldolase
• Kuaj ntshav rau cov kab mob autoimmune
• ECG
• Electromyography (EMG)
• Magnetic resonance duab (MRI)
• Nqaij xyoob
• Nqaij xyoob tawv nqaij
• Lwm yam kev kuaj mob qog noj ntshav
• Xoo hluav taws xob xoo thiab CT scan ntawm lub hauv siab
• Lub ntsws muaj nuj nqi kuaj
• Kev nqos kawm
• Myositis tshwj xeeb thiab mob cuam tshuam autoantibodies

Kev kho tseem ceeb yog kev siv tshuaj corticosteroid. Cov koob tshuaj ntawm cov tshuaj yog maj mam kaw tawm raws li cov leeg ua kom muaj zog. Qhov no yuav siv sijhawm li 4 txog 6 lub lim tiam. Koj tuaj yeem nyob ntawm qhov tsis tshua muaj tshuaj corticosteroid tom qab ntawd.

Cov tshuaj noj rau tshuaj tiv thaiv kab mob hauv lub cev tej zaum yuav raug siv los hloov corticosteroids. Cov tshuaj no suav nrog azathioprine, methotrexate lossis mycophenolate.

Cov kev kho mob uas yuav sim thaum muaj kab mob uas tseem ciaj txawm tias cov tshuaj no yog:

• Qhov muaj zog gamma globulin
• Cov tshuaj lom neeg

Thaum koj cov leeg ua kom muaj zog, koj tus kws kho mob yuav qhia koj kom maj mam txo qis koj cov koob tshuaj. Ntau tus neeg uas muaj tus mob no yuav tsum noj tshuaj hu ua prednisone tas lawv lub neej.

Yog tias mob qog ua rau tus mob, cov leeg tsis muaj zog thiab tawm pob tuaj yeem zoo dua thaum cov qog tshem tawm.

Cov tsos mob yuav ploj mus kiag rau qee tus neeg, xws li menyuam yaus.

Tus mob yuav tuag taus rau cov neeg laus vim:

• Mob leeg tsis muaj zog
• Khoom noj khoom haus tsis muaj zog
• Mob ntsws o
• Lub ntsws tsis ua haujlwm

Qhov loj ua rau muaj kev tuag nrog tus mob no yog mob ntsws thiab mob ntsws.

Cov tib neeg muaj kab mob ntsws nrog cov tshuaj tiv thaiv MDA-5 muaj qhov tsis pom tus mob tsis zoo txawm tias kho tam sim no.

Teeb meem yuav suav nrog:

• Mob ntsws
• Mob raum tsis ua hauj lwm
• Mob Cancer (malignancy)
• Kev mob siab ntawm lub plawv
• Mob tej pob txha

Hu rau koj tus kws kho mob yog tias koj cov leeg ua tsis muaj zog lossis lwm cov tsos mob ntawm tus mob no.

• Dermatomyositis - Gottron papule
• Dermatomyositis - Gottron's papules ntawm txhais tes
• Dermatomyositis - daim tawv muag heliotrope
• Dermatomyositis rau ntawm txhais ceg
• Dermatomyositis - Gottron papule
• Paronychia - candidial
• Dermatomyositis - ua mob rau mob rau ntawm lub ntsej muag

Aggarwal R, Rider LG, Ruperto N, li al. 2016 American College of Rheumatology / European League tawm tsam Rheumatism Cov Qauv rau tsawg tshaj plaws, Nruab Nrab, thiab Chaw Kho Mob Loj hauv Kev Kho Kab Mob Hauv Cov Neeg Dermatomyositis thiab Polymyositis: Kev Tshuaj Ntsuam Xyuas Myositis Thoob Ntiaj Teb thiab Kev Ntsuam Xyuas Pab Pawg / Kab Mob Rheumatology Thoob Ntiaj Teb Kev Tshawb Nrhiav Kev Koom Tes Ua Haujlwm. Mob Pob Txha RheumatolCov. 2017; 69 (5): 898-910. PMID: 28382787 www.ncbi.nlm.nih.gov/pubmed/28382787.

Dalakas MC. Cov leeg mob. N Engl J MedCov. Xyoo 2015; 373 (4): 393-394. PMID: 26200989 www.ncbi.nlm.nih.gov/pubmed/26200989.

Nagaraju K, Gladue HS, Lundberg IE. Cov mob o ntawm cov leeg nqaij thiab lwm yam mob myopathies. Hauv: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley thiab Firestein Cov Ntawv Phau Ntawv ntawm RheumatologyCov. 10 tus ed. Philadelphia, PA: Elsevier; 2017: chap 85.

Lub Koom Haum Hauv Lub Tebchaws rau Tsis tshua muaj teeb meem lub vev xaib. Dermatomyositis. rarediseases.org/rare-diseases/dermatomyositis/. Nkag mus rau lub Plaub Hlis 1, 2019.