Folate-deficiency anemia

Folate-deficiency anemia yog txoj kev txo qis cov ntshav liab (ntshav liab) vim yog tsis muaj cov folate. Folate yog hom vitamin B ntau. Nws tseem hu ua folic acid.

Kauj ntshav yog ib qho mob uas lub cev tsis muaj cov qe ntshav liab liab noj qab nyob zoo. Cov ntshav liab muab cov pa oxygen rau cov cev nqaij.

Folate (folic acid) xav tau cov ntshav liab los ua thiab loj hlob. Koj tuaj yeem folate los ntawm kev noj zaub ntsuab nplooj thiab nplooj siab. Txawm li cas los xij, koj lub cev tsis khaws cov folate hauv qhov loj. Yog li, koj yuav tsum noj zaubmov ntau nplua mias kom tswj tau cov vitamins no kom ntau.

Hauv cov tshuaj folate-deficiency anemia, cov qe ntshav liab ntshav ntau dhau lawm. Cov hlwb zoo li no hu ua macrocytes. Lawv kuj hu ua megaloblasts, thaum lawv pom hauv cov leeg pob txha. Yog li ntawv thiaj pom tus mob ntshav siab ntshav tseem hu ua megaloblastic anemia.

Cov ua rau mob ntshav khov li no:

• Muaj folic acid ntau me ntsis hauv koj cov khoom noj
• Hemolytic anemia
• Ntev ntev kev haus cawv
• Siv qee yam tshuaj noj (xws li phenytoin [Dilantin], methotrexate, sulfasalazine, triamterene, pyrimethamine, trimethoprim-sulfamethoxazole, thiab barbiturates)

Cov hauv qab no ua rau koj qhov kev pheej hmoo rau hom ntshav khov:

• Kev quav cawv
• Noj zaub ntau
• Noj zaub mov tsis zoo (feem ntau pom hauv cov neeg pluag, cov laus neeg, thiab cov neeg uas tsis noj txiv hmab txiv ntoo lossis zaub tshiab)
• Cev xeeb tub
• Lub cev yuag yuag

Folic acid xav tau los pab tus menyuam hauv plab txoj kev loj hlob zoo. Ntau cov folic acid thaum lub sijhawm cev xeeb tub tuaj yeem ua rau muaj qhov tsis xws ntawm cov menyuam mos.

Cov tsos mob tuaj yeem suav nrog:

• Nkees
• Neeg tsis muaj zog
• Mob taub hau
• Pallor
• Mob lub qhov ncauj thiab tus nplaig

Tus kws kho mob yuav kuaj xyuas lub cev. Kev ntsuam xyuas uas yuav ua tau muaj xws li:

• Ua kom tiav cov ntshav suav (CBC)
• Qib ntshav liab folate theem

Tsawg zaus, yuav tsum kuaj pob txha ua pob txha.

Lub hom phiaj yog los txheeb xyuas thiab kho qhov ua rau muaj qhov folate deficiency.

Koj tuaj yeem tau txais cov tshuaj folic acid los ntawm qhov ncauj, txhaj rau hauv cov leeg, lossis los ntawm txoj hlab ntshav (muaj qee zaus). Yog tias koj muaj cov folate qis dua vim tias muaj teeb meem nrog koj txoj hnyuv, koj yuav tsum tau kho mus tas koj lub neej.

Kev noj zaub mov noj tuaj yeem pab koj qib. Noj ntau cov zaub ntsuab, nplooj pom thiab txiv hmab txiv ntoo.

Folate-deficiency anemia feem ntau feem ntau teb tau zoo rau kev kho mob tsis pub dhau 3 mus rau 6 lub hlis. Nws yuav zoo dua thaum pib lub hauv paus ntawm qhov tsis muaj peev xwm kho tau.

Cov tsos mob ntawm tus mob anemia tuaj yeem ua rau tsis xis nyob. Hauv cov poj niam cev xeeb tub, folate deficiency tau cuam tshuam nrog neural tube lossis txha caj qaum tsis xws luag (xws li spina bifida) hauv cov menyuam mos.

Lwm yam, cov kev mob hnyav hnyav ntxiv xws li:

• Curly plaub hau plaub hau
• Cov tawv nqaij muaj ntau zuj zus (xim)
• Ntxiv lawm tshob
• Worsening ntawm kab mob plawv lossis plawv nres

Hu rau koj tus kws kho mob yog tias koj muaj cov tsos mob ntawm lub cev folate deficiency.

Noj zaub mov folate ntau yuav pab tiv thaiv cov mob no.

Cov kws tshaj lij pom zoo tias cov poj niam siv sij hawm 400 micrograms (mcg) ntawm folic acid txhua hnub ua ntej lawv cev xeeb tub thiab mus txog thawj 3 lub hlis uas lawv cev xeeb tub.

• Megaloblastic anemia - saib ntshav liab
• Cov qe ntshav

Antony AC. Megaloblastic anemias. Hauv: Hoffman R, Benz EJ, Silberstein LE, li al, eds. Hematology: Qhov Ntsiab Cai thiab Kev Coj UaCov. 7 tus ed. Philadelphia, PA: Elsevier; 2018: chap 39.

Kumar V, Abbas AK, Aster JC. Hematopoietic thiab lymphoid systems. Hauv: Kumar V, Abbas AK, Aster JC, eds. Robbins Basic PathologyCov. 10 tus ed. Philadelphia, PA: Elsevier; 2018: chap 12.