9 Cov Lus Nug Txog Waldenstrom Macroglobulinemia

Zoo Siab

• 1. Puas yog Waldenstrom macroglobulinemia tuaj yeem kho tau?
• 2. Puas yog Waldenstrom macroglobulinemia tuaj yeem mus rau hauv kev zam txim?
• 3. Tsawg npaum li cas Waldenstrom macroglobulinemia tsawg?
• 4. Waldenstrom macroglobulinemia ua haujlwm li cas?
• 5. Puas yog Waldenstrom macroglobulinemia khiav hauv tsev neeg?
• 6. Dab tsi ua rau Waldenstrom macroglobulinemia?
• 7. Ntev npaum li cas koj tuaj yeem nyob nrog Waldenstrom macroglobulinemia?
• 8. Puas yog Waldenstrom macroglobulinemia metastasize?
• 9. Waldenstrom macroglobulinemia kho li cas?
• Cov nqa mus

Waldenstrom macroglobulinemia (WM) yog ib qho kev tsis txaus siab rau qhov tsis yog-Hodgkin's lymphoma pom los ntawm kev ua haujlwm dhau los ntawm cov ntshav dawb uas tsis txawv txav.

Nws yog ib hom mob qog noj ntshav qeeb uas cuam tshuam rau 3 ntawm 1 lab tus tib neeg hauv Asmeskas txhua txhua xyoo, raws li American Cancer Society.

WM tseem qee zaum hu ua:

• Waldenstrom's mob
• lymphoplasmacytic lymphoma
• thawj macroglobulinemia

Yog tias koj tau tsom kwm nrog WM, koj yuav muaj ntau cov lus nug txog tus kabmob. Kawm paub ntau li koj muaj peev xwm ua tau mob qog noj ntshav thiab tshawb nrhiav kev kho mob tuaj yeem pab koj tiv taus tus mob.

Nov yog cov lus teb rau cuaj lus nug uas tuaj yeem pab koj kom nkag siab zoo dua WM.

1. Puas yog Waldenstrom macroglobulinemia tuaj yeem kho tau?

WM tam sim no tsis muaj tshuaj kho tau. Txawm li cas los xij, muaj ntau txoj kev kho kom zoo los pab koj tswj hwm koj tus mob.

Qhov kev xam pom rau cov neeg kuaj mob nrog WM tau txhim kho ntau xyoo dhau los. Cov kws tshawb fawb tseem tab tom tshawb nrhiav cov tshuaj tiv thaiv los pab ua kom lub cev tiv thaiv kab mob tsis muaj peev xwm tsis kam lees mob qog noj ntshav thiab hom kev kho mob tshiab.

2. Puas yog Waldenstrom macroglobulinemia tuaj yeem mus rau hauv kev zam txim?

Muaj lub sijhawm me me uas WM tuaj yeem mus ua kev zam txim, tab sis nws tsis tshua muaj. Cov kws kho mob tsuas pom kev kho tus mob tag nrho hauv ob peb tus neeg. Cov kev kho tam sim no tsis tiv thaiv kom rov huam mob.

Thaum tsis muaj cov ntaub ntawv ntau npaum li cas txog kev them nqi kho mob, ib txoj kev tshawb fawb me me ntawm 2016 pom tias nrog WM tau hloov mus ua kom tiav tom qab tau kho nrog "R-CHOP regimen."

Tus cai R-CHOP nrog rau kev siv:

• rituximab
• cyclophosphamide
• vincristine
• doxorubicin
• prednisone

Lwm tus neeg koom nrog 31 tau ua tiav ib nrab ntawm kev so.

Tham nrog koj tus kws kho mob saib seb qhov kev kho mob no, lossis lwm txoj cai kho mob, yog txoj cai rau koj.

3. Tsawg npaum li cas Waldenstrom macroglobulinemia tsawg?

Cov kws kho mob txheeb xyuas 1,000 rau 1,500 tus neeg hauv Tebchaws Meskas nrog WM txhua xyoo, raws li American Cancer Society. Lub Koom Haum Tebchaws ntawm Cov Tsis Muaj Kab Mob Tsis Txaus Siab tias nws yog qhov xwm txheej tsis tshua muaj mob.

WM nyhav rau cuam tshuam ob zaug ntau npaum li txiv neej yam li nws yog poj niam. Tus kab mob no muaj tsawg dua ntawm cov neeg dub dua nws yog ntawm cov neeg dawb.

4. Waldenstrom macroglobulinemia ua haujlwm li cas?

WM nyhav rau kev kawm nce qeeb. Nws tsim qee yam ntawm cov qe ntshav dawb hu ua B lymphocytes.

Cov kab mob no tsim cov kab mob ntau dhau ntawm cov tshuaj tiv thaiv hu ua immunoglobulin M (IgM), uas ua rau cov ntshav thooj ntshav hu ua hyperviscosity. Qhov no ua rau nws cov kabmob thiab cov ntaub so ntswg ua haujlwm tsis zoo.

Qhov ntau tshaj ntawm B lymphocytes tuaj yeem tawm hauv chav me me hauv cov pob txha pob txha rau cov qe ntshav tsis muaj mob. Koj tuaj yeem pib ua kom ntshav tsawg yog tias koj cov ntshav liab tsawg dua.

Qhov uas tsis muaj cov qe ntshav dawb yuav ua rau koj lub cev tsis yooj yim tawm tsam lwm yam kev kis mob. Koj cov platelets kuj tseem tuaj yeem poob, uas tuaj yeem ua rau ntshav los ntshav thiab los ntshav.

Qee tus neeg tsis hnov ​​cov tsos mob rau ntau xyoo tom qab kuaj pom tseeb.

Cov tsos mob thaum ntxov muaj kev nkees thiab qaug zog ua rau lub zog tsis muaj ntshav. Koj tuaj yeem muaj tingling hauv koj cov ntiv tes thiab ntiv taw thiab los ntshav hauv koj lub qhov ntswg thiab cov pos hniav.

WM thaum kawg yuav cuam tshuam rau cov kabmob, ua rau o hauv daim siab, hnoos qeev, thiab cov qog ntshav. Hyperviscosity los ntawm tus kab mob tuaj yeem tuaj yeem ua rau pom kev tsis pom kev lossis teeb meem nrog ntshav ntws mus rau qhov retina.

Kab mob qog nqaij hlav thaum kawg tej zaum yuav ua rau mob hlwb zoo li vim yog ntshav khiav tsis zoo rau lub hlwb, ntxiv rau teeb meem mob plawv thiab raum.

5. Puas yog Waldenstrom macroglobulinemia khiav hauv tsev neeg?

Cov kws tshawb fawb tseem tab tom kawm txog WM, tab sis lawv ntseeg tias cov caj ces muaj peev xwm nce qee cov neeg muaj feem yuav muaj tus mob no.

Nyob ib ncig ntawm 20 feem pua ​​ntawm cov neeg uas muaj hom kabmob kheesxaws no yuav nyob ze rau ib tus neeg uas muaj WM lossis lwm tus kabmob uas ua rau cov hlwb B tsis txawv txav.

Feem ntau cov neeg tau kuaj pom tias muaj WM tsis muaj keeb kwm tsev neeg ntawm tus mob no. Feem ntau nws tshwm sim los ntawm kev hloov pauv ntawm tes, uas tsis tau txais los ntawm noob neej, thoob plaws hauv tib neeg lub neej.

6. Dab tsi ua rau Waldenstrom macroglobulinemia?

Cov kws tshawb fawb tseem tsis tau taw qhia qhov tseeb ua rau WM. Cov pov thawj qhia tias cov khoom sib xyaw ntawm caj ces, ib puag ncig, thiab kis tau thoob plaws hauv tus neeg lub neej yuav ua rau tus kab mob loj hlob tuaj.

Kev hloov pauv ntawm tus kab mob MYD88 tshwm sim hauv kwv yees li 90 feem pua ​​ntawm cov neeg muaj Waldenstrom macroglobulinemia, raws li International Waldenstrom's Macroglobulinemia Foundation (IWMF).

Qee cov kev tshawb fawb pom qhov kev sib txuas ntawm tus kab mob siab C thiab WM hauv qee (tab sis tsis yog txhua tus) cov neeg uas muaj tus kab mob no.

Raug rau cov khoom hauv tawv, roj hmab, cov kuab tshuaj, xim ua paug, thiab xim tsev kuj tuaj yeem ua rau qee yam ntawm WM. Tshawb nrhiav seb dab tsi ua rau WM txuas ntxiv.

7. Ntev npaum li cas koj tuaj yeem nyob nrog Waldenstrom macroglobulinemia?

Cov kev tshawb fawb tsis ntev los no qhia tau tias ib nrab ntawm cov neeg uas muaj WM yog cia siab tias yuav muaj sia nyob rau 14 txog 16 xyoo tom qab lawv kuaj pom, raws li IWMF.

Koj txoj kev xam pom ib tus neeg yuav txawv nyob ntawm:

• koj lub hnub nyoog
• noj qab haus huv tag nrho
• yuav kho tus mob sai li cas

Tsis zoo li lwm hom mob cancer, WM tsis kuaj pom ntawm theem. Hloov chaw, cov kws kho mob siv cov International Prognostic Scoring System rau Waldenstrom Macroglobulinemia (ISSWM) los ntsuas koj cov kev xam pom.

Qhov system no suav nrog ntau yam hauv paus, suav nrog koj:

• muaj hnub nyoog
• ntshav hemoglobin qib
• platelet suav
• beta-2 microglobulin qib
• monoclonal IgM qib

Raws li koj cov qhab-nees rau cov kev pheej hmoo no, koj tus kws kho mob tuaj yeem tso koj nyob hauv pawg qis, nruab nrab-lossis ib qho kev pheej hmoo siab, uas tuaj yeem pab koj kom nkag siab zoo dua txog koj qhov kev pom.

5 xyoo kev muaj sia nyob rau cov tib neeg hauv pab pawg uas tsis tshua muaj neeg tsawg yog 87 feem pua, pab pawg neeg pheej hmoo nruab nrab yog 68 feem pua, thiab pab pawg muaj kev pheej hmoo siab yog 36 feem pua, raws li American Cancer Society.

Cov txheeb cais no yog saib raws cov ntaub ntawv los ntawm 600 tus neeg kuaj mob nrog WM thiab kho ua ntej Lub Ib Hlis 2002.

Cov kev kho tshiab dua tuaj yeem muab txoj kev xav zoo dua.

8. Puas yog Waldenstrom macroglobulinemia metastasize?

Yog lawm. WM cuam tshuam cov lymphatic ntaub so ntswg, uas pom nyob hauv ntau qhov chaw ntawm lub cev. Txog thaum ib tus neeg raug txheeb xyuas tus kabmob muaj tus kabmob, nws tuaj yeem pom muaj kab mob rau hauv cov ntshav thiab pob txha pob txha.

Nws tuaj yeem kis mus rau cov qog ntshav, lub siab, thiab hnoos qeev. Tsis tshua muaj mob, WM kuj tseem tuaj yeem metastasize hauv lub plab, lub qog caj pas, tawv nqaij, lub ntsws, thiab txoj hnyuv.

9. Waldenstrom macroglobulinemia kho li cas?

Kev kho mob rau WM sib txawv ntawm ib tug neeg mus rau lwm tus thiab feem ntau tsis tau pib kom txog thaum koj muaj tsos mob los ntawm tus kab mob. Qee tus neeg yuav tsis xav tau kev kho mob txog ob peb xyoos tom qab kuaj pom lawv tus mob.

Koj tus kws kho mob yuav pom zoo kom pib kho thaum qee qhov mob tshwm sim los ntawm mob cancer, suav nrog:

• hyperviscosity mob
• anemia
• leeg puas tsuaj
• teeb meem hauv nruab nrog cev
• amyloidosis
• cryoglobulins

Muaj ntau txoj kev kho kom zoo los pab koj tswj cov tsos mob. Cov kev kho mob dav dav rau WM suav nrog:

• plasmapheresis
• kev kho tshuaj
• hom phiaj kho
• tshuaj kho mob

Muaj qee zaus, koj tus kws kho mob yuav pom zoo kom kho tsawg, xws li:

• tshem tawm ntawm spleen
• hloov raum
• hluav taws xob kho

Cov nqa mus

Raug kuaj pom tias muaj mob qog nqaij hlav tsawg li WM tuaj yeem dhau los.

Txawm li cas los xij, tau txais cov ntaub ntawv los pab koj kom nkag siab zoo dua txog koj tus mob thiab kev xaiv khomob, tuaj yeem pab koj txoj kev ntseeg siab dua txog koj qhov kev cia siab.