Kev Ntsuas Cell-Dawb DNA Kev kuaj mob

Zoo Siab

• Qhov kev kuaj cev xeeb tub tsis muaj DNA (cfDNA) yog dab tsi?
• Dab tsi yog siv rau?
• Vim Li Cas Kuv Thiaj Yuav Tsum Tau Tshawb Kev kuaj mob cfDNA thaum cev xeeb tub?
• Yuav muaj dab tsi tshwm sim thaum kuaj mob cfDNA thaum cev xeeb tub?
• Kuv puas yuav tau ua dab tsi los npaj rau qhov kev xeem no?
• Puas muaj kev pheej hmoo rau kev kuaj?
• Cov txiaj ntsig li cas?
• Puas muaj lwm yam ntxiv uas kuv xav paub txog tshuaj ntsuam cev xeeb tub cfDNA?
• Ua tim khawv

Qhov kev kuaj cev xeeb tub tsis muaj DNA (cfDNA) yog dab tsi?

Kev kuaj cev xeeb tub tsis muaj DNA (cfDNA) kev kuaj ntshav yog kuaj ntshav rau cov poj niam cev xeeb tub. Thaum cev xeeb tub, qee qhov ntawm tus me nyuam hauv plab faib rau leej niam cov hlab ntsha. Kev kuaj mob cfDNA kuaj xyuas qhov DNA no kom paub seb tus menyuam puas muaj peev xwm ua kom muaj tus mob Down syndrome lossis lwm qhov kev cuam tshuam los ntawm kev tsis mob.

Lub voos xwm txheej yog kev cuam tshuam ntawm cov chromosomes. Cov chromosomes yog cov ntu ntawm koj lub hlwb uas muaj koj cov noob caj noob ces. Cov noob yog cov seem ntawm DNA tso tawm los ntawm koj niam thiab koj txiv. Lawv nqa cov ntaub ntawv uas txiav txim siab koj cov xeeb ceem tshwj xeeb, xws li qhov siab thiab xim qhov muag.

• Tib neeg ib txwm muaj 46 chromosomes, muab faib ua 23 khub, nyob hauv txhua lub cell.
• Yog tias ib qho ntawm cov khub no muaj ib daim qauv ntxiv ntawm chromosome, nws tau hu ua trisomy. Lub trisomy ua rau muaj kev hloov hauv txoj kev ntawm lub cev thiab paj hlwb.
• Hauv Down syndrome, muaj ib daim ntawv ntxiv ntawm cov chromosome 21. Qhov no tseem hu ua trisomy 21. Down syndrome yog cov kev mob ntsws tshaj plaws nyob hauv Tebchaws Meskas.
• Lwm qhov kev ua rau mob hlwb xws li Edwards syndrome (trisomy 18), qhov twg muaj ib daim ntawv ntxiv ntawm cov chromosome 18, thiab Patau syndrome (trisomy 13), qhov twg muaj ib daim ntawv ntxiv ntawm cov chromosome 13. Cov kev tsis zoo no muaj tsawg tab sis hnyav dua Down syndrome. Feem ntau cov menyuam mos nrog trisomy 18 lossis trisomy 13 tuag nyob rau thawj xyoo ntawm lub neej.

Kev kuaj mob cfDNA yuav muaj kev pheej hmoo tsawg rau koj thiab koj tus menyuam, tab sis nws tsis tuaj yeem qhia koj paub meej tias koj tus menyuam puas muaj mob ntsws chromosome. Koj tus kws kho mob yuav xav kom kuaj lwm yam kom paub tseeb los yog txiav txim tawm qhov kev kuaj mob.

Lwm lub npe: DNA-dawb tus me nyuam hauv plab, cffDNA, kev kuaj tsis muaj menyuam hauv plab, NIPT

Dab tsi yog siv rau?

Kev kuaj cfDNA feem ntau siv los qhia seb koj tus menyuam tsis tau yug menyuam yog muaj kev pheej hmoo ntau rau cov kev mob hauv qab no:

• Mob syndrome (trisomy 21)
• Cov Mob Edwards (trisomy 18)
• Cov Mob Hlaws (Patis syndrome (trisomy 13)

Kev kuaj mob kuj tseem siv tau:

• Txheeb xyuas tus menyuam lub neej (poj niam txiv neej). Qhov no tuaj yeem ua tau yog tias ib qho ultrasound qhia tau tias tus menyuam lub chaw mos tsis meej txiv neej lossis poj niam. Qhov no tuaj yeem tshwm sim los ntawm kev tsis sib deev ntawm cov txiv neej pw ua ke.
• Kuaj ntshav Rh hom. Rh yog ib co protein nyob ntawm cov ntshav liab. Yog tias koj muaj protein, koj pom tias Rh positive. Yog tias koj tsis them, koj yog Rh tsis zoo. Yog tias koj muaj Rh tsis zoo thiab koj tus menyuam yug hauv plab yog Rh zoo, koj lub cev tiv thaiv kab mob tej zaum yuav tua koj tus menyuam cov qe ntshav. Yog tias koj pom tias koj muaj Rh tsis zoo thaum ntxov hauv lub cev xeeb tub, koj tuaj yeem noj tshuaj los tiv thaiv koj tus menyuam los ntawm cov kev mob txaus ntshai.

Kev kuaj mob cfDNA tuaj yeem ua tiav thaum ntxov hnub thib 10 lub lim tiam ntawm cev xeeb tub.

Vim Li Cas Kuv Thiaj Yuav Tsum Tau Tshawb Kev kuaj mob cfDNA thaum cev xeeb tub?

Ntau tus kws kho mob pom zoo qhov kev kuaj mob no rau cov poj niam cev xeeb tub uas muaj qhov pheej hmoo ntawm kev muaj menyuam ua rau muaj kev puas hlwb chromosome. Tej zaum koj yuav muaj feem ntau dua yog tias:

• Koj hnub nyoog 35 lossis laus dua. Leej niam lub hnub nyoog yog qhov pheej hmoo pheej hmoo ua rau muaj menyuam nrog Down Syndrome lossis lwm yam kev ntshaus siab. Txoj kev pheej hmoo yuav nce zuj zus thaum tus poj niam laus zuj zus.
• Koj tau muaj lwm tus menyuam uas muaj kev puas hlwb chromosome.
• Koj qhov me nyuam hauv plab tsis zoo li qub.
• Lwm txoj kev kuaj cev xeeb tub tsis yog ib txwm.

Qee cov kws kho mob pom zoo ntsuas rau txhua tus poj niam cev xeeb tub. Qhov no vim hais tias kev tshuaj ntsuam yuav luag tsis muaj kev phom sij thiab muaj qhov siab ntawm qhov raug piv nrog lwm yam kev kuaj ntsuas ua ntej yug.

Koj thiab koj tus kws kho mob yuav tsum sib tham yog tias kev kuaj mob cfDNA zoo rau koj.

Yuav muaj dab tsi tshwm sim thaum kuaj mob cfDNA thaum cev xeeb tub?

Tus kws kho mob yuav kuaj ntshav ntawm txoj hlab ntshav hauv koj txhais caj npab, siv rab koob me me. Tom qab cov koob raug tso nkag, cov ntshav me me yuav raug sau rau hauv lub khob kuaj lossis vial. Koj tuaj yeem hnov ​​me ntsis thaum cov koob nkag mus lossis tawm. Qhov no feem ntau yuav siv sijhawm tsawg dua tsib feeb.

Kuv puas yuav tau ua dab tsi los npaj rau qhov kev xeem no?

Koj yuav tsum tham nrog tus kws sab laj tswv caj ces ua ntej koj mus kuaj. Tus kws pab tswv yim txog caj ces yog tus kws tshaj lij kawm tiav los ntawm kev tshawb fawb caj ces thiab kev tshuaj ntsuam caj ces. Nws tuaj yeem piav qhia cov txiaj ntsig tau tshwm sim thiab qhov nws tuaj yeem txhais tau rau koj thiab koj tus menyuam.

Puas muaj kev pheej hmoo rau kev kuaj?

Nws tsis muaj kev pheej hmoo rau koj tus menyuam mos hauv plab thiab kev pheej hmoo tsawg rau koj. Koj yuav muaj mob me lossis doog ntshav ntawm qhov chaw tso rab koob, tab sis feem ntau cov tsos mob ploj mus sai.

Cov txiaj ntsig li cas?

Yog tias koj cov txiaj ntsig tau tsis zoo, nws tsis zoo li koj tus menyuam muaj Down Syndrome lossis lwm tus kev voos. Yog tias koj cov txiaj ntsig tau zoo, nws txhais tau tias muaj ntau qhov kev pheej hmoo uas koj tus menyuam muaj ib qho ntawm cov kev tsis zoo no. Tab sis nws tsis tuaj yeem qhia koj kom paub meej tias koj tus menyuam raug cuam tshuam dab tsi. Txhawm rau paub tseeb dua kev kuaj mob koj yuav xav tau lwm yam kev kuaj, xws li amniocentesis thiab chorionic villus sampling (CVS). Cov kev ntsuam xyuas no feem ntau yog cov txheej txheem muaj kev nyab xeeb heev, tab sis lawv muaj qhov pheej hmoo me me uas ua rau muaj menyuam me.

Yog tias koj muaj lus nug txog koj cov txiaj ntsig tau, tham nrog koj tus kws kho mob thiab / lossis tus kws pab tswv yim txog caj ces.

Kawm paub ntau ntxiv txog cov kev sim hauv chaw soj ntsuam, cov chaw siv ntsuas, thiab nkag siab cov txiaj ntsig tau.

Puas muaj lwm yam ntxiv uas kuv xav paub txog tshuaj ntsuam cev xeeb tub cfDNA?

Kev kuaj mob cfDNA tsis muaj tseeb rau cov poj niam cev xeeb tub muaj ntau dua ib tus menyuam (menyuam ntxaib, peb npaug, lossis ntau dua).

Ua tim khawv

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Cov ntaub ntawv ntawm lub xaib no yuav tsum tsis txhob siv los hloov chaw kho mob lossis tswv yim kho mob. Hu rau kws kho mob yog tias koj muaj lus nug txog koj txoj kev noj qab haus huv.