Txhua Yam Koj Yuav Tsum Paub Txog Johnson & Johnson's COVID-19 Vaccine

Zoo Siab

• Cov tshuaj tiv thaiv Johnson & Johnson COVID-19 ua haujlwm li cas?
• Qhov tshuaj tiv thaiv Johnson & Johnson COVID-19 muaj txiaj ntsig zoo li cas?
• Cov ntaub ntawv mob COVID-19 mob hnyav thiab tuag
• COVID-19 Variants
• Koj puas xav tau cov tshuaj tiv thaiv Johnson & Johnson COVID-19 ntau npaum li cas?
• Johnson & Johnson cov tshuaj tiv thaiv cuam tshuam li cas rau kis los ntawm COVID-19?
• Ntsuam xyuas rau

Thaum Lub Ob Hlis 26, FDA pawg neeg tawm tswv yim tshuaj tiv thaiv tau pom zoo pom zoo rau Johnson & Johnson cov tshuaj tiv thaiv COVID-19 rau kev siv thaum muaj xwm txheej ceev. Qhov ntawd txhais tau tias txhaj tshuaj tiv thaiv - uas xav tau tsuas yog txhaj ib zaug - tuaj yeem npaj tau siv hauv Asmeskas thaum kawg Lub Peb Hlis, raws li Lub Chaw Haujlwm Tshawb Fawb Kab Mob thiab Txoj Cai (CIDRAP).

Tab sis, Johnson & Johnson cov tshuaj tiv thaiv COVID-19 zoo li cas? Thiab nws piv rau lwm yam tshuaj tiv thaiv COVID-19 los ntawm Pfizer thiab Moderna li cas? Nov yog yam koj yuav tsum paub.

Cov tshuaj tiv thaiv Johnson & Johnson COVID-19 ua haujlwm li cas?

Yog tias koj paub txog COVID-19 cov tshuaj tiv thaiv tsim los ntawm Pfizer thiab Moderna, tej zaum koj yuav paub tias lawv yog ob qho tshuaj mRNA. Qhov ntawd txhais tau tias lawv ua haujlwm los ntawm kev nkag mus rau ib feem ntawm tus kab mob SARS-CoV-2 tus kab mob spike protein (ib feem ntawm tus kab mob uas txuas nws tus kheej rau cov hlwb hauv koj lub cev) thiab siv cov ntawv encoded los ua kom muaj kev tiv thaiv kab mob los ntawm koj lub cev kom nws tsim. tshuaj tiv thaiv kab mob. (Saib: Kev Siv Tshuaj Tiv Thaiv COVID-19 Zoo Li Cas?)

Cov tshuaj tiv thaiv Johnson & Johnson ua haujlwm txawv me ntsis. Rau ib yam, nws tsis yog txhaj tshuaj mRNA. Nws yog cov tshuaj tiv thaiv adenovector, uas txhais tau tias nws siv tus kab mob inactivated (hauv qhov no, adenovirus, uas ua rau mob khaub thuas) raws li tus vector xa cov protein (hauv qhov no, cov protein ntau los ntawm SARS-CoV-2) uas koj lub cev yuav lees paub tias yog kev hem thawj thiab tsim cov tshuaj tiv thaiv tiv thaiv, hais tias Brittany Busse, MD, koom nrog tus thawj coj kho mob ntawm WorkCare.

Tam sim no, koj yuav xav tsis thoob yog tias muab "tus kab mob inactivated" rau hauv koj lub cev yuav ua rau koj mob tsis xwm yeem, tab sis nws yuav tsis ua. Abisola Olulade, MD, tus kws kho mob tsev tshuaj muaj ntawv pov thawj ntawm Sharp Rees-Stealy Medical Group hais tias "Tus kab mob inactivated tsis tuaj yeem rov ua dua lossis ua rau koj mob." Hloov chaw, adenovirus hauv Johnson & Johnson cov tshuaj tiv thaiv COVID-19 tsuas yog ua tus nqa khoom (lossis "vector") ntawm SARS-CoV-2's spike protein gene rau hauv koj lub hlwb, ua rau lub hlwb ua cov ntawv luam ntawm cov noob, nws piav qhia. Xav txog cov noob caj noob ces raws li cov lus qhia txog yuav ua li cas koj lub cev tuaj yeem tawm tsam SARS-CoV-2, ntxiv Dr. Olulade. Nws piav qhia "Cov protein no tuaj yeem lees paub los ntawm koj lub cev tiv thaiv kab mob thiab ua rau koj tsim cov tshuaj tiv thaiv uas yuav tiv thaiv tiv thaiv COVID," nws piav qhia. (FYI: Kev txhaj tshuaj tiv thaiv khaub thuas ua haujlwm zoo ib yam.)

Thaum cov tshuaj tiv thaiv kab mob no txawv ntawm Pfizer thiab Moderna, nws tsis yog lub tswvyim tshiab. Oxford thiab AstraZeneca's COVID tshuaj tiv thaiv - uas tau pom zoo siv hauv EU thiab UK thaum Lub Ib Hlis (FDA tam sim no tab tom tos cov ntaub ntawv los ntawm AstraZeneca qhov kev sim tshuaj ua ntej txiav txim siab Asmeskas kev tso cai, New York Times ceeb toom) - siv cov cuab yeej zoo sib xws adenovirus. Johnson & Johnson kuj tseem siv thev naus laus zis los tsim nws cov tshuaj tiv thaiv Ebola, uas tau pom tias muaj kev nyab xeeb thiab muaj txiaj ntsig zoo hauv kev tsim cov tshuaj tiv thaiv kab mob hauv lub cev.

Qhov tshuaj tiv thaiv Johnson & Johnson COVID-19 muaj txiaj ntsig zoo li cas?

Hauv kev sim tshuaj loj loj ntawm ze li ntawm 44,000 tus neeg, Johnson & Johnson cov tshuaj tiv thaiv COVID-19 tau pom tias yog 66 feem pua ​​​​zoo tag nrho hauv kev tiv thaiv ib nrab (txhais tau tias muaj ib lossis ntau dua cov tsos mob ntawm COVID-19) mus rau COVID-19 hnyav (tus cwj pwm los ntawm nkag mus rau ICU, ua pa tsis ua haujlwm, lossis lub cev tsis ua haujlwm, ntawm lwm yam) 28 hnub tom qab txhaj tshuaj tiv thaiv, raws li xov xwm tshaj tawm los ntawm lub tuam txhab. (Cov ntaub ntawv "yuav xa mus rau ib phau ntawv xov xwm tshuaj xyuas hauv lub lis piam tom ntej," hais cov xov xwm tshaj tawm.)

Johnson & Johnson kuj tau qhia tias nws cov tshuaj tiv thaiv qib ntawm kev tiv thaiv kev tiv thaiv kab mob qis mus rau qhov hnyav yog 72 feem pua ​​​​hauv Asmeskas, 66 feem pua ​​​​hauv Latin America, thiab 57 feem pua ​​​​hauv South Africa (uas, qhov nruab nrab ua ke, muab rau koj tag nrho 66 feem pua ​​​​ntawm cov txiaj ntsig). . Yog tias cov lej zoo li tsis txaus ntseeg, nws tsim nyog sau cia tias, los ntawm kev sib piv, kev txhaj tshuaj tiv thaiv khaub thuas tsuas yog 40 txog 60 feem pua ​​muaj txiaj ntsig zoo los tiv thaiv lub cev los ntawm tus mob khaub thuas, tab sis nws tseem ua lub luag haujlwm tseem ceeb hauv kev txo kev mob hauv tsev kho mob thiab tuag, hais tias Dr. Olulade. (Txog: Kev txhaj tshuaj tiv thaiv kab mob khaub thuas tiv thaiv koj los ntawm tus mob coronavirus?)

Cov ntaub ntawv mob COVID-19 mob hnyav thiab tuag

Thaum xub thawj, Johnson & Johnson qhov kev txhaj tshuaj tiv thaiv kab mob 66 ​​feem pua ​​yuav zoo li me ntsis, tshwj xeeb tshaj yog thaum koj muab piv rau cov txiaj ntsig los ntawm Moderna (94.5 feem pua ​​muaj txiaj ntsig) thiab Pfizer ("ntau dua 90 feem pua ​​muaj txiaj ntsig," raws li lub tuam txhab). Tab sis yog tias koj khawb tob, Johnson & Johnson cov ntaub ntawv ua qhia ntau qhov kev cia siab, tshwj xeeb tshaj yog thaum nws los txog rau qhov mob hnyav tshaj plaws ntawm COVID-19.

Thoob plaws txhua cheeb tsam, cov tshuaj tiv thaiv yog 85 feem pua ​​ua tau zoo hauv kev tiv thaiv COVID-19 hnyav, raws li Johnson & Johnson cov ntawv tshaj tawm. Qhov tseeb, lub tuam txhab tau sau tseg tias nws cov tshuaj tiv thaiv tau pom "ua tiav kev tiv thaiv tiv thaiv COVID-cuam tshuam nrog tsev kho mob thiab tuag" 28 hnub tom qab txhaj tshuaj tiv thaiv, "tsis muaj qhov xwm txheej qhia" ntawm COVID-ntsig txog tsev kho mob lossis tuag ntawm cov uas tau txais Johnson & Johnson txhaj tshuaj tiv thaiv.

Hais txog qhov tshwm sim tshwm sim, Johnson & Johnson tau hais tias nws cov tshuaj tiv thaiv COVID yog "feem ntau ua tau zoo" thoob plaws txhua tus neeg koom nrog hauv kev sim. Lub tuam txhab cov ntaub ntawv thaum ntxov qhia tias cov tshuaj tiv thaiv yuav ua rau "mob-rau-mob mob tshwm sim feem ntau cuam tshuam nrog kev txhaj tshuaj," suav nrog qaug zog, mob taub hau, mob nqaij, thiab mob qhov chaw txhaj tshuaj.

COVID-19 Variants

Tsis zoo li Pfizer's thiab Moderna cov kev tshawb fawb, Johnson & Johnson qhov kev sim tshuaj tiv thaiv suav nrog cov txiaj ntsig thoob plaws ntau thaj chaw - suav nrog cov uas tsis ntev los no tau pom qhov nce siab hauv COVID cov xwm txheej tshwm sim los ntawm qhov sib txawv ntawm tus kab mob. Dr. Olulade sau tseg tias "[Cov kev hloov pauv no] yuav tsis muaj qhov tseem ceeb thaum lub sijhawm cov tshuaj tiv thaiv yav dhau los tau kawm," Tau kawg, cov kws tshawb fawb tam sim no tab tom saib seb ua tau zoo li cas tag nrho Cov tshuaj tiv thaiv COVID-19 tuaj yeem tiv thaiv lub cev los ntawm kev sib txawv ntawm COVID-19 sib txawv. Txog tam sim no, Dr. Busse hais tias UK kev hloov pauv "tsis zoo li yuav muaj kev txhawj xeeb txog COVID cov tshuaj tiv thaiv." Txawm li cas los xij, nws ntxiv, nyob ntawd yog Kev kwv yees tias qhov sib txawv ntawm COVID los ntawm South Africa thiab Brazil tuaj yeem "hloov txoj kev tiv thaiv kab mob cuam tshuam nrog tus kabmob" thiab muaj peev xwm ua rau cov tshuaj tiv thaiv "tsis zoo." (Txog: Vim Li Cas Tus Kab Mob Khaus Viv-19 tshiab kis tau sai dua?)

Qhov ntawd tau hais tias, thaum cov tshuaj tiv thaiv yuav tsis tiv thaiv COVID-19 tag nrho, nws zoo li pab tib neeg kom zam dhau tus kab mob phem tshaj plaws. "Qhov ntawd kuj txhais tau tias nws muaj peev xwm los txo lub nra ntawm peb cov kev saib xyuas kev noj qab haus huv ntau dhau thiab ua rau peb nyob ze rau lub teeb ntawd thaum kawg ntawm lub qhov av," hais tias Dr. Olulade.

"Nws tseem ceeb heev uas yuav tsum nco ntsoov tias sai npaum li cas peb tuaj yeem tau txais tib neeg txhaj tshuaj, qhov hloov pauv tsawg dua tus kab mob yuav tsum hloov pauv thiab rov ua dua," Dr. Olulade hais ntxiv. "Yog vim li cas peb thiaj li yuav tsum tau txhaj tshuaj tiv thaiv txhua tus kom sai li sai tau."

Koj puas xav tau cov tshuaj tiv thaiv Johnson & Johnson COVID-19 ntau npaum li cas?

Ib cag los ntawm qhov ua tau zoo ntawm cov tshuaj tiv thaiv nws tus kheej, cov kws tshaj lij hais tias Johnson & Johnson's COVID kev txhaj tshuaj tiv thaiv kuj tseem cog lus vim tias nws tsuas xav tau txhaj tshuaj nkaus xwb, hos Pfizer's thiab Moderna txhaj tshuaj tiv thaiv kab mob ib leeg yuav tsum tau txhaj tshuaj ob zaug los ntawm ob peb lub lis piam.

Dr. Olulade hais tias "Qhov no tuaj yeem yog qhov hloov pauv tiag tiag," "Peb pom tias qee tus neeg mob, hmoov tsis zoo, tsis rov qab los rau lawv qhov koob thib ob," yog li qhov no ib-thiab-ua tiav txoj hauv kev tuaj yeem txhais tau rau ntau qhov kev txhaj tshuaj tag nrho.

Lwm qhov txiaj ntsig tseem ceeb rau Johnson & Johnson cov tshuaj tiv thaiv COVID? Cov koob tshuaj pom tau yooj yim dua khaws thiab faib ntau dua li Pfizer's thiab Moderna cov tshuaj tiv thaiv, ua tsaug rau J & J kev siv tshuaj tiv thaiv kab mob adenovector. "Adenovirus [hauv Johnson & Johnson cov tshuaj tiv thaiv] pheej yig dua thiab tsis yooj yim li [raws li mRNA hauv Pfizer's thiab Moderna cov tshuaj tiv thaiv]," tom kawg uas yuav tsum tau khaws cia ntawm qhov txias txias, piav qhia Dr. Busse. "Cov tshuaj tiv thaiv Johnson & Johnson ruaj khov hauv lub tub yees ntev txog peb lub hlis, uas ua rau nws yooj yim dua rau xa thiab faib rau cov uas xav tau."

Johnson & Johnson cov tshuaj tiv thaiv cuam tshuam li cas rau kis los ntawm COVID-19?

"Nws nyuam qhuav dhau los qhia," hais tias Prabhjot Singh, MD, Ph.D., tus kws saib xyuas kev noj qab haus huv thiab kws tshawb fawb ntawm CV19 CheckUp, cov cuab yeej online uas pab ntsuas koj li kev pheej hmoo ntawm COVID-19. Qhov ntawd mus rau tag nrho ntawm cov tshuaj tiv thaiv COVID-19 peb tau pom txog tam sim no BTW, tsis yog Johnson & Johnson, sau tseg Dr. Singh. "Kev tshawb fawb thaum ntxov qhia tias kev pheej hmoo kis yuav tsum qis dua tom qab txhaj tshuaj tiv thaiv kab mob, tab sis cov lus teb meej yuav tsum muaj kev kawm raug cai," nws piav qhia.

Txij li cov tshuaj tiv thaiv cuam tshuam rau COVID kis tseem tsis tau paub, nws yog qhov tseem ceeb tshaj uas yuav tsum hnav lub qhov ncauj txuas ntxiv thiab tswj koj qhov nrug deb ntawm cov neeg sab nrauv koj lub tsev, hais tias Dr. Olulade. (Tos, koj puas yuav tsum tau npog ob zaug los tiv thaiv COVID-19?)

Kab hauv qab: Txhua ntawm cov tshuaj tiv thaiv no zoo li muaj kev tiv thaiv tseem ceeb tiv thaiv COVID-19, uas yog qhov zoo heev. Tseem, "tshuaj tiv thaiv tsis yog daim ntawv tso cai tso koj tus neeg zov," piav qhia Dr. Olulade. "Peb yuav tsum xav txog kev noj qab haus huv thiab kev noj qab haus huv ntawm lwm tus uas tseem tsis tau txhaj tshuaj tiv thaiv thiab tseem yuav tsis muaj kev tiv thaiv los ntawm COVID."

Cov ntaub ntawv hauv zaj dab neeg no muaj tseeb raws li lub sijhawm nias. Raws li kev hloov tshiab hais txog tus mob coronavirus COVID-19 txuas ntxiv mus, nws muaj peev xwm hais tias qee cov ntaub ntawv thiab cov lus pom zoo hauv zaj dab neeg no tau hloov pauv txij li kev tshaj tawm thawj zaug. Peb txhawb kom koj mus xyuas tsis tu ncua nrog cov peev txheej xws li CDC, WHO, thiab koj lub chaw saib xyuas kev noj qab haus huv hauv zos kom paub cov ntaub ntawv tshiab thiab cov lus pom zoo.

Ntsuam xyuas rau