Guillain-Barré Syndrome

Zoo Siab

• Dab tsi ua rau mob Guillain-Barré syndrome?
• Cov tsos mob ntawm Guillain-Barré syndrome zoo li cas?
• Yuav kuaj pom Guillain-Barré li cas?
• Tus txha nqaj qaum
• Electromyography
• Kev soj ntsuam leeg
• Yuav kho tus mob Guillain-Barré li cas?
• Plasmapheresis (ntshav sib pauv)
• Tso tshuaj immunoglobulin
• Lwm yam kev kho mob
• Cov teeb meem muaj tshwm sim ntawm Guillain-Barré syndrome yog dab tsi?
• Dab tsi yog qhov ntev ntawm kev saib xyuas?

Guillain-Barré syndrome yog dab tsi?

Guillain-Barré syndrome yog ib qho tsis tshua muaj tab sis mob hnyav ua rau lub cev ua rau lub cev tsis muaj zog tiv thaiv kev noj qab haus huv cov hlab ntsha hauv koj lub paj hlwb tsis zoo (PNS).

Qhov no ua rau lub zog tsis muaj zog, loog thiab tingling, thiab thaum kawg nws tuaj yeem ua rau tuag tes tuag taw.

Cov ua kom muaj tus mob no tseem tsis tau paub, tab sis feem ntau nws tshwm sim los ntawm kev kis mob, xws li lub plab zom mov (mob rau lub plab lossis plab hnyuv) lossis mob ntsws.

Guillain-Barré yog qhov tsis tshua muaj, cuam tshuam tsuas yog li ntawm 1 ntawm 100,000 tus neeg Asmeskas, raws li National Institute ntawm Neurological Disorder thiab Stroke.

Tsis muaj kev kho mob rau tus mob tus mob, tab sis kev kho mob tuaj yeem txo qhov hnyav ntawm koj cov tsos mob thiab txo qhov ncua sij hawm ntawm tus mob.

Muaj ntau ntau hom Guillain-Barré, tab sis feem ntau daim ntawv yog mob inflammatory demyelinating polyradiculoneuropathy (CIDP). Nws ua rau kev puas tsuaj rau myelin.

Lwm hom muaj xws li Miller Fisher syndrome, uas cuam tshuam rau cov leeg ntshav cranial.

Dab tsi ua rau mob Guillain-Barré syndrome?

Qhov tseeb ua rau Guillain-Barré tsis paub meej. Raws li qhov, kwv yees li ob feem peb ntawm cov neeg uas muaj Guillain-Barré tau txhim kho nws sai sai tom qab lawv tau muaj mob rawsplab lossis mob ntsws ua pa.

Qhov no qhia tau tias qhov tsis muaj zog tiv thaiv kab mob rau cov kev mob dhau los ua rau muaj qhov tsis sib haum.

Campylobacter jejuni muaj mob tau cuam tshuam nrog Guillain-Barré. Campylobacter yog ib qho ntawm cov kab mob feem ntau ua rau mob raws plab hauv tebchaws Meskas. Nws tseem yog qhov pheej hmoo txaus ntshai tshaj plaws rau Guillain-Barré.

Campylobacter yog feem ntau pom muaj hauv cov khoom noj hauv qab noj, tshwj xeeb cov nqaij qaib.

Cov kab mob hauv qab no tau cuam tshuam nrog Guillain-Barré:

• khaub thuas
• cytomegalovirus (CMV), uas yog tus cwj pwm ntawm tus mob herpes
• Kab mob Epstein-Barr (EBV), lossis mob mononucleosis
• mycoplasma mob ntsws, uas yog kev mob ntsws atypical los ntawm cov kab mob xws li cov kab mob
• HIV lossis AIDS

Txhua tus neeg tuaj yeem kis tau Guillain-Barré, tab sis nws yog ib qho muaj ntau ntawm cov neeg laus.

Tsis tshua muaj xwm txheej, tib neeg tuaj yeem tsim kev kub ntxhov nyob rau hnub los yog lub lis piam tom qab tau txais a.

CDC thiab Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) muaj cov kab ke los saib xyuas kev nyab xeeb ntawm cov tshuaj tiv thaiv, kuaj pom cov kev mob tshwm sim thaum ntxov, thiab sau tseg txhua kis ntawm Guillain-Barré uas txhim kho tom qab txhaj tshuaj tiv thaiv.

CDC uas tshawb fawb qhia tau hais tias koj muaj feem ntau yuav kis Guillain-Barré los ntawm kev mob khaub thuas, ntau dua li cov tshuaj tiv thaiv.

Cov tsos mob ntawm Guillain-Barré syndrome zoo li cas?

Hauv Guillain-Barre syndrome, koj lub nruab nrog cev tiv thaiv koj lub paj hlwb peripheral.

Cov hlab ntsha hauv koj lub paj hlwb txuas nrog koj lub hlwb mus rau tas koj lub cev thiab xa cov cim qhia rau koj cov leeg.

Cov leeg yuav tsis muaj peev xwm teb tau rau cov phiajcim lawv tau txais los ntawm koj lub hlwb yog tias cov hlab ntsha no puas.

Thawj qhov tsos mob no feem ntau yog ib qho kev ntxim nyiam nyob hauv koj cov ntiv taw, ko taw, thiab ceg. Kev qog ntiv tes kis mus rau sab caj npab thiab ntiv tes.

Cov tsos mob tuaj yeem hloov mus sai heev. Hauv qee leej neeg, tus kab mob no tuaj yeem loj heev hauv ob peb teev.

Cov tsos mob ntawm Guillain-Barré muaj xws li:

• tingling lossis prickling kev xav hauv koj cov ntiv tes thiab ntiv taw
• leeg tsis muaj zog hauv koj txhais ceg uas mus rau koj lub cev sab saud thiab mob heev zuj zus
• nyuaj taug kev khov kho
• teeb meem txav koj ob lub qhov muag lossis lub ntsej muag, tham, zom, los yog nqos
• mob sab nraub qaum
• poob ntawm lub zais zis tswj
• lub plawv dhia ceev
• ua pa nyuaj
• tuag tes tuag taw

Yuav kuaj pom Guillain-Barré li cas?

Guillain-Barré nyuaj rau kev kuaj mob thaum xub thawj. Qhov no yog vim tias cov tsos mob zoo ib yam li lwm cov kev mob hlwb lossis cov mob uas cuam tshuam rau cov leeg hlwb, xws li botulism, mob hlwb, lossis mob hnyav hlau.

Kev haus luam yeeb hnyav hnyav tuaj yeem tshwm sim los ntawm cov khoom xws li cov hlau lead, mercury, thiab arsenic.

Koj tus kws kho mob yuav nug cov lus nug txog qee cov tsos mob thiab koj li kev mob dhau los. Nco ntsoov qhia koj tus kws kho mob txog cov tsos mob txawv txav thiab yog tias koj tau muaj mob lossis kab mob tshiab lossis yav dhau los.

Cov kev xeem nram no yog siv los pab tshawb nrhiav kom paub tseeb:

Tus txha nqaj qaum

Tus txha caj qaum (caj pas txha cajqaum) koom nrog nqus cov kua dej me me los ntawm koj tus nqaj qaum rau koj sab nraub qaum. Cov kua dej no hu ua cerebrospinal kua. Koj cov kua mis cerebrospinal yog tom qab ntawd sim ua kom pom cov protein ntau.

Cov neeg uas muaj Guillain-Barré feem ntau muaj protein ntau dua-dua li ib txwm muaj nyob hauv lawv cov kua hlwb cerebrospinal.

Electromyography

Ib daim duab electromyography yog kuaj cov hlab ntsha ua haujlwm. Nws nyeem cov kev siv hluav taws xob los ntawm cov leeg los pab koj tus kws kho mob paub yog tias koj cov leeg tsis muaj zog yog mob los ntawm cov hlab ntshav lossis cov leeg puas.

Kev soj ntsuam leeg

Txoj kev tshawb fawb ntawm kev soj ntsuam leeg hauv lub paj hlwb yuav siv los ntsuas seb koj lub siab zoo thiab cov leeg ua li cas rau lub tshuab hluav taws xob me me.

Yuav kho tus mob Guillain-Barré li cas?

Guillain-Barré yog ib qho kev tiv thaiv kabmob tiv thaiv kab mob uas ua rau nws tus kheej txwv, txhais tau tias nws yuav daws nws tus kheej. Txawm li cas los xij, ib tus neeg uas muaj tus mob no yuav tsum tau mus nyob hauv tsev kho mob kom tau saib ze. Cov tsos mob tuaj yeem ua rau mob ceev ceev thiab tuaj yeem tuag taus yog tias tsis kho.

Thaum muaj mob hnyav, cov neeg uas muaj Guillain-Barré muaj peev xwm tuag tes tuag taw tag nrho. Guillain-Barré tuaj yeem yog ib qho kev phom sij yog tias tuag tes tuag taw cuam tshuam rau daim npog lossis caj pas hauv siab, tiv thaiv kev ua pa zoo.

Lub hom phiaj ntawm txoj kev kho yog kom txo qis qhov kev tiv thaiv ntawm lub cev tiv thaiv kab mob thiab txhawb koj lub cev ua haujlwm, xws li lub ntsws ua haujlwm, thaum koj lub zog rov zoo.

Cov kev kho mob yuav suav nrog:

Plasmapheresis (ntshav sib pauv)

Lub cev tiv thaiv kab mob ua rau cov protein hu ua cov tshuaj tiv thaiv kev tawm tsam uas ib txwm tua cov phom sij txawv teb chaw, xws li cov kab mob thiab kab mob. Guillain-Barré tshwm sim thaum lub cev tiv thaiv kab mob tsis ncaj ncees ua rau cov tshuaj tiv thaiv ua rau lub zog noj qab haus huv ntawm koj lub paj hlwb.

Plasmapheresis yog tsim los kom tshem tawm cov tshuaj tiv thaiv cov hlab ntshav ntawm cov ntshav ntawm koj cov ntshav.

Thaum ua cov txheej txheem no, cov ntshav yuav tshem tawm koj lub cev los ntawm lub tshuab. Lub tshuab no tshem cov tshuaj tawm ntawm koj cov ntshav thiab tom qab ntawd rov qab cov ntshav rov rau koj lub cev.

Tso tshuaj immunoglobulin

Kev txhaj tshuaj tiv thaiv kab mob siab (immunoglobulin) ntau tseem tuaj yeem pab thaiv lub cev cov tshuaj tiv thaiv uas ua rau Guillain-Barré. Immunoglobulin muaj cov tshuaj tiv thaiv zoo rau lub cev tsis muaj zog.

Plasmapheresis thiab tshuaj tiv thaiv immunoglobulin yog qhov zoo sib xws. Nws yog nyob ntawm koj thiab koj tus kws kho mob txhawm rau txiav txim siab seb qhov kev kho mob zoo tshaj plaws.

Lwm yam kev kho mob

Koj yuav tau muab tshuaj kom daws qhov mob thiab tiv thaiv kom ntshav txhaws thaum koj tsis nyob ntev.

Tej zaum koj yuav tau txais kev kho mob ntawm lub cev thiab ntawm lub cev. Thaum ntu mob taub hau, tus neeg zov me nyuam yuav maj mam txav koj ob sab caj npab thiab ob txhais ceg kom lawv hloov tau.

Thaum koj pib rov ua kom zoo, tus kws kho mob yuav ua haujlwm nrog koj txog kev ua kom cov nqaij muaj zog thiab cov haujlwm ntawm kev ua neej txhua hnub (ADLs). Qhov no tuaj yeem suav nrog kev ua si ntawm tus kheej, xws li kev hnav khaub ncaws.

Cov teeb meem muaj tshwm sim ntawm Guillain-Barré syndrome yog dab tsi?

Guillain-Barré cuam tshuam koj txoj hlab ntshav. Kev qaug zog thiab tuag tes tuag taw uas tshwm sim tuaj yeem cuam tshuam rau ntau qhov ntawm koj lub cev.

Cov teeb meem no suav nrog kev ua pa nyuaj thaum lub zog tuag tes tuag taw lossis cov tsis muaj zog kis mus rau cov leeg uas tswj kev ua pa. Tej zaum koj yuav xav tau lub tshuab hu ua lub tshuab ntsuas pa los pab koj ua pa yog tias qhov no tshwm sim.

Teeb meem kuj tseem muaj xws li:

• lingering tsis muaj zog, loog, lossis lwm yam kev khib tshwj xeeb txawm tias tom qab rov ua haujlwm
• teeb meem lub plawv lossis ntshav siab
• kev mob
• maj mam plob tsis so tswj los yog zais zis muaj nuj nqi
• ntshav txhaws thiab txaj vim yog tuag tes tuag taw

Dab tsi yog qhov ntev ntawm kev saib xyuas?

Lub sijhawm rov qab los rau Guillain-Barré tuaj yeem siv sijhawm ntev, tab sis feem ntau cov neeg muaj mob.

Feem ntau, cov tsos mob yuav mob heev dua rau ob mus rau plaub lub lis piam ua ntej lawv yuav nyob ruaj khov. Kev rov qab nqa tuaj yeem siv nyob txhua qhov chaw los ntawm ob peb lub lis piam mus rau ob peb xyoos, tab sis feem ntau txoj kev zoo rov qab rau hauv 6 txog 12 hlis.

Li ntawm 80 feem pua ​​ntawm cov neeg cuam tshuam los ntawm Guillain-Barré tuaj yeem taug kev ntawm nws tus kheej thaum rau lub hlis, thiab 60 feem pua ​​rov qab tau lawv cov leeg lub cev tsis muaj zog hauv ib xyoos.

Rau qee qhov, rov qab siv sijhawm ntev dua. Nyob ib ncig ntawm 30 feem pua ​​tseem pom qee qhov tsis muaj zog tom qab peb xyoos.

Txog 3 feem pua ​​ntawm cov neeg cuam tshuam los ntawm Guillain-Barré yuav ntsib kev mob tshwm sim ntawm cov tsos mob, zoo li tsis muaj zog thiab mob nkees, txawm ntau xyoo tom qab qhov xwm txheej dhau los.

Muaj qee zaus, qhov xwm txheej no tuaj yeem ua rau tuag tau, tshwj xeeb yog tias koj tsis nrhiav kev kho. Qhov tseeb uas yuav ua rau kom tshwm sim tsis zoo muaj xws li:

• hnub nyoog siab heev
• mob hnyav los sis hnyav zuj zus
• kev kho mob qeeb, uas tuaj yeem ua rau cov leeg puas tsuaj ntau dua
• Lub caij nyoog siv lub tshuab ua pa, tuaj yeem ua rau koj mob ntsws

Cov ntshav txhaws thiab thaj chaw pw uas tshwm sim los ntawm immobilized tuaj yeem txo qis. Ua kom ntshav txhaws thiab tso zis nias kom tsawg yuav txhaws.

Nquag rov ua dua ntawm koj lub cev txo qhov ntev ntawm lub cev uas ua rau cov ntaub so ntswg rhuav tshem, lossis txaj pw.

Ntxiv nrog rau koj cov tsos mob ntawm lub cev, koj yuav ntsib kev nyuaj siab. Nws tuaj yeem ua qhov nyuaj los kho rau kev txav mus nyob tsawg thiab muaj kev vam khom ntxiv rau lwm tus. Tej zaum koj yuav pom tias nws yog ib qho muaj txiaj ntsig zoo los tham nrog tus kws kho mob.