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Tsuas yog ob peb hnub tom qab Pfizer's COVID-19 tshuaj tiv thaiv tau txais kev tso cai siv xwm txheej ceev los ntawm Food and Drug Administration, qee tus neeg twb tau txhaj tshuaj lawm. Thaum Lub Kaum Ob Hlis 14, 2020, thawj koob tshuaj Pfizer tau muab rau cov neeg ua haujlwm noj qab haus huv thiab cov neeg ua haujlwm hauv tsev laus. Hauv ob peb lub hlis thiab lub hlis tom ntej, cov tshuaj tiv thaiv yuav txuas ntxiv mus rau cov pej xeem, nrog cov neeg ua haujlwm tseem ceeb thiab cov neeg laus yog thawj tus tau txais koob tshuaj tom qab cov kws tshaj lij saib xyuas kev noj qab haus huv zoo. (Saib: Thaum twg yuav muaj tshuaj tiv thaiv COVID-19 - thiab leej twg yuav tau txais thawj zaug?)

Nws yog lub sijhawm txaus siab, tab sis yog tias koj tau pom cov ntawv ceeb toom txog COVID-19 cov tshuaj tiv thaiv "mob hnyav" phiv, koj yuav muaj qee cov lus nug txog dab tsi uas yuav cia siab thaum nws yog koj tig los txhaj tshuaj. Nov yog yam koj yuav tsum paub txog cov tshuaj tiv thaiv COVID-19 cov kev mob tshwm sim.


Ua ntej tshaj, rov qab saib seb qhov tshuaj tiv thaiv COVID-19 ua haujlwm li cas.

Cov tshuaj tiv thaiv COVID-19 los ntawm Pfizer thiab Moderna-qhov kawg ntawm qhov kev cia siab tias yuav tau txais kev tso cai xwm txheej ceev nyob rau ob peb hnub-siv hom tshuaj tiv thaiv tshiab hu ua messenger RNA (mRNA). Hloov chaw tso tus kab mob tsis muaj zog hauv koj lub cev (zoo li ua tiav nrog txhaj tshuaj tiv thaiv khaub thuas), mRNA cov tshuaj tiv thaiv ua haujlwm los ntawm kev sau ib feem ntawm cov protein ntau uas pom muaj nyob ntawm SARS-CoV-2 (tus kab mob uas ua rau COVID-19). Cov khoom ntawm cov protein uas tau teev tseg tom qab ntawd ua rau muaj kev tiv thaiv kab mob hauv koj lub cev, ua rau koj tsim cov tshuaj tiv thaiv uas tuaj yeem tiv thaiv koj los ntawm tus kab mob yog tias koj kis tus kab mob, Amesh A. Adalja, MD, tus kws tshaj lij ntawm Johns Hopkins Centers for Health Security, yav tas los hais Cov duab. (Ntau ntxiv nyob ntawm no: Puas Muaj Kev Tiv Thaiv COVID-19?)

Xav txog cov txheej txheem protein uas tau muab zais raws li caj ces "tus ntiv tes" rau tus kab mob SARS-CoV-2, hais tias Thad Mick, Pharm.D., tus lwm thawj ntawm cov kws kho mob thiab cov kev pabcuam kuaj mob ntawm ZOOM+Care. "Lub hom phiaj ntawm COVID-19 cov tshuaj tiv thaiv kab mob yog txhawm rau qhia cov kab mob voos ntiv tes uas ceeb toom koj lub cev thaum ntxov kom lub cev tiv thaiv kab mob lees paub tias nws tsis nyob ntawd thiab tsim kev tiv thaiv kab mob rau nws ua ntej tus kab mob muaj txoj hauv kev los hla koj. natural defenses, "nws piav qhia.


Hauv tus txheej txheem ntawm kev txhim kho qhov kev tiv thaiv kab mob tiv thaiv kab mob, nws ib txwm muaj los ntsib qee yam kev phiv nyob hauv txoj kev, ntxiv rau Mick.

Hom tshuaj tiv thaiv COVID-19 hom phiv dab tsi kuv yuav tsum tau txais?

Raws li tam sim no, peb tsuas muaj kev tshawb fawb ua ntej txog cov ntaub ntawv muaj kev nyab xeeb ntawm Pfizer's thiab Moderna's COVID-19 cov tshuaj tiv thaiv. Zuag qhia tag nrho, txawm li cas los xij, Pfizer cov tshuaj tiv thaiv tau hais tias muaj "kev nyab xeeb zoo", thaum Moderna zoo ib yam qhia tias "tsis muaj kev txhawj xeeb txog kev nyab xeeb loj." Ob lub tuam txhab hais tias lawv tau txuas ntxiv mus sau cov ntaub ntawv kev nyab xeeb (thiab ua tau zoo) kom paub meej cov kev tshawb pom no.

Qhov ntawd tau hais tias, ib yam li kev txhaj tshuaj tiv thaiv, koj tuaj yeem ntsib qee qhov kev mob tshwm sim los ntawm cov tshuaj tiv thaiv COVID-19. Lub Chaw Tiv Thaiv Kab Mob thiab Tiv Thaiv tau sau cov tshuaj tiv thaiv COVID-19 cov kev mob tshwm sim ntawm nws lub vev xaib:

  • Mob thiab o ntawm qhov chaw txhaj tshuaj
  • Ua npaws
  • Ua daus no
  • Kev qaug zog
  • Mob taub hau

Lwm yam tshuaj tiv thaiv COVID-19 tej zaum yuav muaj xws li mob nqaij thiab mob pob qij txha, ntxiv Mick. "Los ntawm qhov peb paub, feem ntau cov kev mob tshwm sim yuav tshwm sim thawj hnub lossis ob hnub tom qab tau txais cov tshuaj tiv thaiv, tab sis tej zaum yuav tshwm sim tom qab," nws piav qhia. (Nws tsim nyog sau cia tias kev txhaj tshuaj tiv thaiv khaub thuas zoo ib yam.)


Yog tias cov kev mob tshwm sim no zoo li zoo li cov tsos mob ntawm COVID-19, qhov ntawd yog vim lawv yeej yog. "Kev txhaj tshuaj tiv thaiv kab mob tiv thaiv kab mob," piav qhia Richard Pan, MD, kws kho menyuam yaus thiab xeev California tus neeg sawv cev. "Feem ntau ntawm cov kev mob tshwm sim yog cov tsos mob ntawm cov lus teb xws li kub taub hau, qaug zog, mob taub hau, thiab mob leeg."

Txawm li cas los xij, qhov ntawd tsis txhais tau tias tshuaj tiv thaiv COVID-19 tuaj yeem muab COVID-19 rau koj, sau ntawv Dr. Pan. "Nws yog ib qho tseem ceeb kom nco ntsoov tias mRNA [los ntawm cov tshuaj tiv thaiv] tsis cuam tshuam rau ib qho ntawm koj cov cell," nws piav qhia. Qhov tseeb, qhov mRNA tsuas yog ib daim qauv txheej txheem ib ntus ntawm cov protein ntau nyob rau saum npoo ntawm tus kab mob. "Lub hom phiaj no yog qhov yooj yim heev, yog vim li cas cov tshuaj tiv thaiv yuav tsum tau khaws cia txias ua ntej yuav siv," Dr. Pan hais. Koj lub cev thaum kawg tshem tawm daim phiaj xwm ntawd tom qab koj tau txhaj tshuaj, tab sis cov tshuaj tiv thaiv uas koj tsim los teb yuav nyob, nws piav qhia. (CDC sau tseg tias yuav tsum muaj cov ntaub ntawv ntau ntxiv kom paub tseeb tias cov tshuaj tiv thaiv kab mob tsim los ntawm COVID-19 yuav kav ntev npaum li cas.)

Dr. Pan hais ntxiv tias "Nws tsis tuaj yeem ntes COVID-19 los ntawm kev txhaj tshuaj, ib yam li muaj daim phiaj rau tsim lub kauj tsheb tsis muab txoj hauv kev rau koj los tsim lub tsheb tag nrho,"

Cov tshuaj tiv thaiv COVID-19 tshwm sim li cas?

FDA tseem tab tom tshuaj xyuas cov ntaub ntawv raws nraim li cas qhov tshwm sim ntawm COVID-19 saum toj no tej zaum yuav tshwm sim rau cov pej xeem. Txog tam sim no, txawm li cas los xij, cov ntaub ntawv tshaj tawm los ntawm Pfizer thiab Moderna ntawm lawv qhov kev sim tshuaj kho mob loj tau qhia tias tsawg tus neeg yuav ntsib "cov tsos mob tseem ceeb tab sis ib ntus" tom qab tau txais tshuaj tiv thaiv COVID-19, Dr. Pan hais.

Tshwj xeeb tshaj yog, hauv Moderna qhov kev sim tshuaj tiv thaiv COVID-19, 2.7 feem pua ​​ntawm cov tib neeg tau hnov ​​mob qhov chaw txhaj tshuaj tom qab txhaj thawj zaug. Ua raws li koob tshuaj thib ob (uas tau muab plaub lub lis piam tom qab txhaj thawj zaug), 9.7 feem pua ​​ntawm cov tib neeg ntsib kev qaug zog, 8.9 feem pua ​​qhia txog mob leeg, 5.2 feem pua ​​muaj mob sib koom, 4.5 feem pua ​​qhia tias mob taub hau, 4.1 feem pua ​​ntsib kev mob hnyav, thiab 2 feem pua hais tias qhov txhaj tshuaj thib ob ua rau lawv liab liab ntawm qhov chaw txhaj tshuaj.

Txog tam sim no, Pfizer qhov tshuaj tiv thaiv COVID-19 qhov tshwm sim zoo ib yam li Moderna's. Hauv Pfizer qhov kev sim loj ntawm nws cov tshuaj tiv thaiv, 3.8 feem pua ​​​​ntawm cov neeg tau tshaj tawm tias qaug zog thiab 2 feem pua ​​​​tau mob taub hau, ob qho tib si tom qab koob thib ob (uas tau muab peb lub lis piam tom qab txhaj tshuaj thawj zaug). Tsawg dua 1 feem pua ​​ntawm cov tib neeg hauv kev sim tshuaj kho mob ua npaws (txhais hauv kev tshawb fawb raws li lub cev kub siab tshaj 100 ° F) tom qab txhaj thawj zaug lossis thib ob. Ib tug me me (0.3 feem pua, kom muaj tseeb) ntawm cov neeg tau txais tshuaj tiv thaiv kuj tau tshaj tawm cov qog nqaij hlav o, "uas feem ntau daws tau hauv 10 hnub" ntawm kev txhaj tshuaj, raws li kev tshawb fawb.

Txawm hais tias cov kev mob tshwm sim no ib ntus thiab tsis zoo li qhov tshwm sim, lawv tuaj yeem yog "qhov tseem ceeb" txaus uas qee tus neeg "yuav xav tau ib hnub ua haujlwm" tom qab txhaj tshuaj tiv thaiv, sau Dr.

Koj kuj tseem yuav tau hnov ​​kev txhawj xeeb txog kev ua xua rau Pfizer qhov tshuaj tiv thaiv COVID-19. Tsis ntev tom qab cov tshuaj tiv thaiv tau dov tawm hauv tebchaws Askiv, ob tus neeg ua haujlwm saib xyuas kev noj qab haus huv - uas ob leeg niaj hnub nqa EpiPen thiab muaj keeb kwm ntawm kev tsis haum tshuaj - ntsib anaphylaxis (kev ua xua uas ua rau muaj kev phom sij rau lub neej uas tshwm sim los ntawm kev ua tsis taus pa thiab ntshav siab. ) tom qab lawv thawj koob tshuaj, raws li cov New York Times. Ob tus neeg ua haujlwm saib xyuas kev noj qab haus huv tau rov zoo, tab sis lub sijhawm no, cov kws saib xyuas kev noj qab haus huv hauv tebchaws Askiv tau tshaj tawm lus ceebtoom rau Pfizer qhov tshuaj tiv thaiv COVID-19: "Txhua tus neeg uas muaj keeb kwm anaphylaxis rau tshuaj tiv thaiv, tshuaj, lossis zaub mov yuav tsum tsis tau txais Pfizer/BioNTech tshuaj tiv thaiv. Qhov koob thib ob yuav tsum tsis txhob muab rau txhua tus neeg uas tau ntsib kev tsis haum tshuaj tom qab kev tswj hwm thawj koob tshuaj tiv thaiv no. " (Muaj feem cuam tshuam: Muaj Dab Tsi tshwm sim thaum Koj Mus Rau Qhov Ua Rau Anaphylactic Shock?)

Hauv Teb Chaws Asmeskas, daim ntawv qhia tseeb los ntawm FDA ntawm Pfizer's COVID-19 tshuaj tiv thaiv zoo ib yam hais tias "cov tib neeg uas paub txog keeb kwm ntawm kev tsis haum tshuaj loj (xws li anaphylaxis) rau ib feem ntawm Pfizer-BioNTech Covid-19 Vaccine" yuav tsum tsis txhob txhaj tshuaj tiv thaiv. lub sijhawm no. (Koj tuaj yeem nrhiav tag nrho cov npe khoom xyaw hauv Pfizer tshuaj tiv thaiv hauv tib daim ntawv tseeb los ntawm FDA.)

Vim Li Cas Koj Thiaj Li Yuav Tau Txais Tshuaj Tiv Thaiv COVID-19, Tsis hais Teeb Meem Li Cas

Qhov tseeb yog, koj yuav xav tias zoo li ib hnub lossis ob hnub tom qab koj tau txais tshuaj tiv thaiv COVID-19. Tab sis tag nrho txhua yam, cov tshuaj tiv thaiv COVID-19 yog "muaj kev nyab xeeb dua" ntau dua li tus kab mob nws tus kheej, uas tau tua kwv yees li 300,000 tus neeg hauv Asmeskas, hais tias Dr. Pan.

Cov tshuaj tiv thaiv COVID-19 tsis yog yuav pab xwb koj zam qhov teeb meem loj ntawm COVID-19, tab sis lawv tseem yuav pab tiv thaiv cov neeg uas tsis tau tsis tau txhaj tshuaj tiv thaiv (xws li cov neeg muaj kev tsis haum tshuaj hnyav, cov neeg cev xeeb tub, thiab cov uas muaj hnub nyoog qis dua 16 xyoo), ntxiv Dr. Pan. (Kev hnav koj daim npog ntsej muag, kev nyob sib nrug deb, thiab ntxuav koj txhais tes kuj tseem yog qhov tseem ceeb hauv kev tiv thaiv tib neeg los ntawm COVID-19.)

"Txawm hais tias ntau tus neeg txhawj xeeb txog cov tshuaj tiv thaiv COVID-19, muaj ntau yam txiaj ntsig los txhaj tshuaj tiv thaiv," Mick piav qhia. "Cov tshuaj tiv thaiv no tau tshuaj xyuas zoo thiab tsuas yog yuav ua lag luam yog tias muaj kev pheej hmoo ntawm cov tshuaj tiv thaiv ntau dua los ntawm cov txiaj ntsig."

Cov ntaub ntawv hauv zaj dab neeg no muaj tseeb raws li lub sijhawm nias. Raws li kev hloov tshiab hais txog tus mob coronavirus COVID-19 txuas ntxiv mus, nws muaj peev xwm hais tias qee cov ntaub ntawv thiab cov lus pom zoo hauv zaj dab neeg no tau hloov pauv txij li kev tshaj tawm thawj zaug. Peb txhawb kom koj mus xyuas tsis tu ncua nrog cov peev txheej xws li CDC, WHO, thiab koj lub chaw saib xyuas kev noj qab haus huv hauv zos kom paub cov ntaub ntawv tshiab thiab cov lus pom zoo.

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