Nug Tus Kws Tshaj Lij: Nkag Siab Cov Toj roob hauv pes ntawm Cov Tshuaj Kho Mob rau Ankylosing Spondylitis

Zoo Siab

• Kho puas tau ankylosing spondylitis?
• Cov kev kho zoo tshaj plaws hauv kev soj ntsuam sim yog dab tsi?
• Kuv yuav paub tau li cas yog tias kuv tsim nyog tau txais kev kuaj mob?
• Cov kev kho tshiab tshaj plaws rau ankylosing spondylitis yog dab tsi?
• Koj pom zoo cov kev kho mob dab tsi? Dab tsi uas koj xav ua?
• Kev phais puas yog qhov kev xaiv los kho tus mob ankylosing spondylitis?
• Koj pom li cas kho kev kho mob ankylosing spondylitis hloov 10 xyoo tom ntej?
• Dab tsi koj xav tias kev ua kom tawg tom ntej rau kev kho mob ntawm ankylosing spondylitis yuav yog?
• Kev thev naus laus zis pab kho ua ntej li cas?

Kho puas tau ankylosing spondylitis?

Tam sim no, tsis muaj txoj kev kho rau tus mob ankylosing spondylitis (AS). Txawm li cas los xij, feem ntau cov neeg mob nrog AS tuaj yeem ua lub neej ntev, muaj txiaj ntsig zoo.

Vim tias lub sijhawm nyob nruab nrab ntawm qhov pib ntawm kev tshwm sim thiab kev paub tseeb ntawm tus kab mob, kev kuaj pom thaum ntxov yog qhov tseem ceeb.

Kev tswj hwm kho mob, kev saib xyuas mob ua ntej, thiab cov hom phiaj qoj ib ce tuaj yeem ua rau cov neeg mob txhim kho lub neej. Cov txiaj ntsig zoo muaj xws li ua kom tsis txhob mob ntxiv, ntau txav ntawm qhov txav, thiab ua kom muaj peev xwm ntxiv tau.

Cov kev kho zoo tshaj plaws hauv kev soj ntsuam sim yog dab tsi?

Cov kev sim tshuaj mob muaj txiaj ntsig zoo tshaj plaws yog cov tshuaj xyuas qhov ua tau zoo thiab kev nyab xeeb ntawm bimekizumab. Nws yog cov tshuaj uas tiv thaiv ob qho tib si interleukin (IL) -17A thiab IL-17F - cov protein me uas ua rau muaj cov tsos mob AS.

Filgotinib (FIL) yog ib qho kev xaiv tshuaj loog ntawm Janus kinase 1 (JAK1), lwm cov teeb meem muaj protein ntau. Tam sim no FIL yog qhov kev txhim kho rau kev kho mob ntawm psoriasis, mob caj dab, thiab AS. Nws tau hais ntawm ncauj thiab muaj hwj chim heev.

Kuv yuav paub tau li cas yog tias kuv tsim nyog tau txais kev kuaj mob?

Koj qhov kev tsim nyog los koom hauv kev sim tshuaj rau AS yog nyob ntawm lub hom phiaj sim.

Kev sim tshuaj tuaj yeem kawm txog qhov ua tau zoo thiab kev nyab xeeb ntawm tshuaj tshuaj, kev txhim kho ntawm pob txha pob txha, lossis lub luag haujlwm ntawm tus kabmob. Kev kho dua ntawm cov txheej txheem kuaj mob rau AS yuav cuam tshuam cov qauv kev soj ntsuam hauv lub neej tom ntej.

Cov kev kho tshiab tshaj plaws rau ankylosing spondylitis yog dab tsi?

Qhov tseeb FDA pom zoo tshuaj rau kev kho mob ntawm AS yog:

• ustekinumab (Stelara), ib qho IL12 / 23 inhibitor
• tofacitinib (Xeljanz), tus JAK inhibitor
• secukinumab (Cosentyx), ib qho IL-17 inhibitor thiab tshuaj tiv thaiv monoclonal tib neeg
• ixekizumab (Taltz), ib qho IL-17 inhibitor

Koj pom zoo cov kev kho mob dab tsi? Dab tsi uas koj xav ua?

Complementary tshuaj uas kuv niaj zaus pom zoo suav nrog:

• zaws
• tshuaj pleev ib ce
• kev acupressure
• Kev ntsuas dej ua kom tawm dag zog

Cov kev tawm dag zog tshwj xeeb suav nrog:

• ncab
• ntsa zaum
• planks
• Muab lub puab tsaig ntsia mus rau hauv txoj hauj lwm tseem ceeb
• ncab ncab
• kev ua pa sib sib zog nqus thiab taug kev

Kev siv cov tswv yim yoga thiab cov hluav taws xob transcutaneous hluav taws xob lub hlwb (TENS) tau kuj xav kom.

Kev phais puas yog qhov kev xaiv los kho tus mob ankylosing spondylitis?

Kev phais mob tsis tshua muaj mob hauv AS. Qee zaum, tus kabmob hloov mus rau qhov cuam tshuam nrog kev ua haujlwm txhua hnub vim yog mob, tsis muaj txav, thiab tsis muaj zog. Hauv cov xwm txheej no, kev phais yuav tsum raug pom zoo.

Muaj ob peb txheej txheem uas tuaj yeem txo qhov mob, ua kom tus txha nraub qaum, txhim kho posture, thiab tiv thaiv kom txhob muaj zog. Pob txha caj qaum, osteotomies, thiab laminectomies ua los ntawm cov kws phais neeg paub heev tuaj yeem muaj txiaj ntsig zoo rau qee cov neeg mob.

Koj pom li cas kho kev kho mob ankylosing spondylitis hloov 10 xyoo tom ntej?

Nws yog kuv txoj kev xav hais tias kev kho yuav kho tau raws li kev tshawb nrhiav hauv chaw kho mob tshwj xeeb, cov tswv yim txhim kho kom zoo dua qub, thiab qhov hais txog tus mob no.

AS ntog hauv qab lub kaus ntawm ntau pawg ntawm cov kab mob hu ua spondyloarthropathies. Cov no suav nrog psoriasis, mob caj dab, mob caj dab, mob plab hnyuv, thiab mob spondyloarthropathy mob.

Muaj peev xwm muab cov lus tshaj tawm ntawm cov pob zeb no thiab cov tib neeg yuav tau txais txiaj ntsig los ntawm kev tsom mus rau kev kho mob.

Dab tsi koj xav tias kev ua kom tawg tom ntej rau kev kho mob ntawm ankylosing spondylitis yuav yog?

Ob lub caj ces tshwj xeeb, HLA-B27 thiab ERAP1, tuaj yeem koom nrog hauv kev hais tawm ntawm AS. Kuv xav tias kev txuas ntxiv tom ntej hauv kev kho mob ntawm AS yuav raug qhia paub los ntawm kev nkag siab seb lawv sib cuam tshuam thiab lawv cov koom ua ke nrog kev kis mob hnyuv.

Kev thev naus laus zis pab kho ua ntej li cas?

Ib qhov loj hlob tau zoo yog hauv nanomedicine. Cov thev naus laus zis no tau siv coj los kho lwm tus mob xws li osteoarthritis thiab mob caj dab. Txoj kev tsim kho ntawm nanotechnology-based kev xa khoom xaib tej zaum yuav yog qhov zoo siab ntxiv rau kev tswj hwm ntawm AS.

Brenda B. Spriggs, MD, FACP, MPH, yog Clinical Professor Emerita, UCSF, Rheumatology, tus kws pab tswv yim rau ntau lub koom haum saib xyuas kev noj qab haus huv, thiab tus kws sau ntawv. Nws cov kev txaus siab suav nrog kev tawm suab pab neeg mob thiab mob siab rau muab kev sab laj rheumatology rau cov kws kho mob thiab cov neeg tsis tau txais kev pab. Nws yog tus sau ua ke ntawm "Tsom rau Koj Txoj Kev Noj Qab Haus Huv Zoo: Phau Ntawv Qhia Ncaj Ncees rau Kev Kho Mob Koj Tsim Nyog."