Cov tshuaj tiv thaiv monoclonal: lawv yog dab tsi thiab vim li cas lawv pab kho cov kab mob

Zoo Siab

• Piv txwv ntawm cov tshuaj tiv thaiv monoclonal
• 1. Trastuzumab
• 2. Denosumab
• 3. Obinutuzumab
• 4. Ustequinumab
• 5. Pertuzumab
• Yuav Ua Li Cas Siv Cov Tshuaj Tiv Thaiv Monoclonal

Cov tshuaj tiv thaiv monoclonal yog cov protein siv los ntawm lub cev tiv thaiv kab mob txhawm rau txheeb xyuas thiab ua kom lub cev txawv teb chaws, uas tuaj yeem yog cov kab mob, kab mob lossis txawm tias cov qog ua haujlwm. Cov protein no yog qhov tshwj xeeb, vim lawv paub txog lub hom phiaj tshwj xeeb, lub hauv paus hu ua antigen, uas yuav muaj nyob hauv cov kab mob txawv teb chaws mus rau lub cev. Nkag siab txog qhov ua haujlwm tiv thaiv kabmob ntawm lub cev ua haujlwm.

Piv txwv cov kab mob monoclonal, xws li denosumab, obinutuzumab lossis ustequinumab, piv txwv li tau tsim tawm hauv chav kuaj, feem ntau zoo ib yam li cov uas pom hauv tib neeg lub cev, uas yuav pab lub cev tawm tsam qee yam kabmob. Yog li, nyob ntawm cov tshuaj monoclonal antibody siv, cov tshuaj no tuaj yeem siv los kho qee cov kab mob loj xws li mob txha caj qaum, mob qog ntshav, plaque psoriasis lossis qee hom mob qog nqaij hlav, xws li mob cancer ntawm lub mis lossis pob txha, piv txwv.

Piv txwv ntawm cov tshuaj tiv thaiv monoclonal

Qee cov qauv ntawm cov kab mob monoclonal muaj xws li:

1. Trastuzumab

Qhov tshuaj tiv thaiv monoclonal, ua lag luam li Herceptin, tau tsim los ntawm kev tsim kho caj ces, thiab tshwj xeeb tawm tsam cov protein uas muaj nyob hauv cov neeg muaj qee yam mob cancer mis thiab lub plab. Yog li, qhov kev hais daws no tau qhia rau kev kho mob qog noj ntshav mis thaum nyuam qhuav pib lossis nrog metastasis thiab mob qog nqaij hlav hauv qib siab.

2. Denosumab

Kev ua lag luam raws li Prolia lossis Xgeva, nws muaj nyob rau hauv nws cov muaj pes tsawg leeg cov tib neeg monoclonal IgG2 cov tshuaj tiv thaiv, uas cuam tshuam nrog kev txiav txim ntawm cov protein tshwj xeeb uas ua rau cov pob txha muaj zog, txo kev pheej hmoo ntawm kev tawg. Yog li, Denosumab yog qhia rau kev kho mob ntawm pob txha loj, pob txha, mob pob txha lossis mob qog nqaij hlav hauv qib siab nrog pob txha metastases (uas tau kis rau cov pob txha).

3. Obinutuzumab

Kuj paub tias kev lag luam yog Gazyva, nws muaj nyob hauv nws cov tshuaj tiv thaiv kev tiv thaiv uas paub thiab tshwj xeeb khi rau cov CD20 protein, pom nyob rau saum npoo ntawm cov qe ntshav dawb lossis B lymphocytes. muaj peev xwm nres qhov kev loj hlob tsis txaus ntawm cov qe ntshav dawb uas ua rau tus kab mob no.

4. Ustequinumab

Qhov kev hais daws no tseem yuav tau paub txog kev ua lag luam raws li Stelara thiab yog tsim los ntawm tib neeg IgG1 monoclonal antibody, uas inhibits cov protein tshwj xeeb uas yog lub luag haujlwm ua rau psoriasis. Yog li, qhov kev hais daws no tau qhia rau kev kho mob ntawm cov quav hniav psoriasis.

5. Pertuzumab

Kuj tseem hu ua Perjeta, nws yog tsim los ntawm cov tshuaj tiv thaiv kab mob monoclonal uas khi rau tib neeg txoj kev loj hlob ntu 2 receptor, tshwm sim hauv qee cov qog nqaij hlav cancer, ua rau qeeb los sis txiav lawv txoj kev loj hlob. Yog li, Perjeta qhia rau kev kho mob cancer mis.

Yuav Ua Li Cas Siv Cov Tshuaj Tiv Thaiv Monoclonal

Cov tshuaj noj nrog Monoclonal Antibodies yuav tsum tsuas yog ua raws li cov lus qhia kho mob, vim tias hom tshuaj tiv thaiv kab mob yuav tsum tau siv thiab cov koob tshuaj pom zoo yuav nce nyob ntawm qhov teeb meem yuav tsum tau kho thiab nws qhov mob hnyav.

Feem ntau, cov kev kho mob no yog siv rau kev kho mob qog noj ntshav, vim tias lawv yog cov tshuaj antineoplastic uas yuav tsum tau siv raws li cov lus qhia tshwj xeeb los ntawm kws kho mob thiab uas yuav tsum tau siv rau hauv tsev kho mob lossis chaw kho mob.