Akinesia yog dab tsi?

Zoo Siab

• Tus pojniam lub ntsej muag akinesia
• Akinesia thiab dyskinesia: Dab tsi yog qhov txawv?
• Cov tsos mob
• Kev Kho Mob
• Cov Tshuaj Kho Mob
• Implantable stimulators
• Tus-dhau-lub khw
• Lwm txoj kev kho mob thiab kho tsev
• Cov ua rau thiab txaus ntshai
• Outlook

Akinesia

Akinesia yog ib lo lus rau qhov tsis muaj peev xwm txav koj cov leeg ua kom zoo. Nws feem ntau tau piav qhia tias yog tus yam ntxwv ntawm tus kab mob Parkinson tus mob (PD). Nws tuaj yeem pom cov tsos mob ntawm lwm yam mob, thiab.

Ib qho ntawm cov tsos mob feem ntau ntawm akinesia yog "khov." Qhov no txhais tau hais tias ib lossis ntau qhov chaw ntawm koj lub cev tsis tuaj yeem txav mus los vim los ntawm lub xeev hlwb, xws li PD. Cov xwm txheej no ua rau cov leeg hlwb (neurons) hauv koj lub hlwb kev txav mus los kom tsis muaj zog thiab tuag. Tom qab ntawd cov neurons tsis tuaj yeem xa cov cim xa mus rau cov leeg thiab cov leeg. Qhov no tuaj yeem ua rau koj poob koj lub peev xwm tswj koj cov leeg. Qhov no tuaj yeem suav cov leeg hauv koj lub ntsej muag, tes, ceg lossis lwm yam nqaij uas koj siv txhua hnub.

Akinesia thiab ntau yam xwm txheej uas ua rau nws hnyav zuj zus. Feem ntau ntawm cov xwm txheej muaj kev vam meej thiab kho tsis tau, tab sis tsis yog txhua yam ntawm lawv. Mob hypothyroidism hnyav tuaj yeem ua rau rov qab mob akinetic syndrome. Cov tshuaj tsis raug mob chaw nres tsheb kuj tseem tuaj yeem thim rov qab.

Cov kev kho mob thiab tshuaj noj kom qeeb mus rau qhov muaj mob ntawm akinesia thiab cov leeg hlwb zoo li PD muaj. Lawv tuaj yeem pab txwv cov teebmeem akinesia muaj rau koj lub neej txhua hnub.

Tus pojniam lub ntsej muag akinesia

Akinesia tuaj yeem tshwm sim rau tus menyuam hauv plab lub tsev menyuam. Tus mob no yog hu ua fetal akinesia. Hauv cov xwm txheej no, menyuam yaus tsis txav mus ntau npaum li qhov lawv yuav tsum ua. Tus mob no kuj tseem tuaj yeem tshwm sim nrog lwm cov tsos mob. Tus menyuam lub ntsws lub ntsws tsis tuaj yeem txhim kho tau lossis tus menyuam yuav yug los ntawm lub ntsej muag txawv txav. Cov tsos mob no tau paub ua tus me nyuam akinesia deformation ua ntu zus (FADS). Feem ntau nws yuav tshwm sim los ntawm lawv cov noob.

Akinesia thiab dyskinesia: Dab tsi yog qhov txawv?

Akinesia txawv ntawm dyskinesia. Dyskinesia tuaj yeem tshwm sim nrog cov xwm txheej uas koj cov leeg sib hloov lossis txav tsis txav. Hauv akinesia, koj tsis tuaj yeem coj ncaj qha rau koj cov leeg kom txav mus (qee zaum nkaus). Tab sis cov leeg nqaij tsis plam lawv qhov peev xwm. Nws yog lub kaw lus extrapyramidal lossis cov chaw txav mus los uas ua txhaum.

Hauv dyskinesia, koj cov leeg yuav txav mus los poob nthav lossis tas li tsis muaj peev xwm tsum. Zoo li akinesia, dyskinesia kuj tseem tuaj yeem tshwm sim hauv cov xwm txheej zoo li PD.

Cov tsos mob

Cov tsos mob feem ntau pom ntawm akinesia yog "khov." Qhov no tuaj yeem ua rau koj lub zog txhav ntawm ib lossis ntau dua cov leeg leeg. Nws tuaj yeem ua rau koj lub ntsej muag zoo li nws khov rau hauv ib lub ntsej muag. Nws tseem tuaj yeem ua rau koj taug kev nrog lub zog sib zog ua lub zog hu ua "gait freezing."

Cov tsos mob no tseem tshwm sim vim yog ib qho mob uas hu ua muaj kev nyuaj siab sai kawg (PSP), uas cuam tshuam rau taug kev thiab sib npaug ua ntej tshaj nyob hauv PD. Lwm cov tsos mob uas tuaj yeem tshwm sim nrog akinesia yog tias koj muaj PD suav nrog:

• co ntawm cov leeg (tshee) hauv koj txhais tes thiab ntiv tes, tshwj xeeb yog thaum koj so lossis ntxhov siab
• muag muag ntawm lub suab los maj mam hais lus
• tsis tuaj yeem sawv ntsug ncaj los yog tswj hwm qee tus cwj pwm
• maj mam txav thiab siv sijhawm ntev kom ua tiav lub cev cov haujlwm (bradykinesia)

Cov tsos mob ntawm PSP uas tej zaum yuav tshwm sim nrog akinesia (tshwj xeeb yog hauv lub ntsej muag) suav nrog:

• lub zeem muag ploj lossis plooj plooj
• tsis muaj peev xwm txav lub qhov muag ceev nrooj
• tsis tuaj yeem saib sab thiab siab yooj yim
• tsis taus qhov muag kom ntev
• muaj teeb meem nqos
• muaj cov tsos mob ntawm kev nyuaj siab, suav nrog ua viav vias

Kev Kho Mob

Cov Tshuaj Kho Mob

Ib qho kev kho mob feem ntau rau akinesia yog qhov tshwm sim ntawm PD yog kev sib xyaw ntawm levodopa, lub hauv nruab nrab cov hlab ntsha ua haujlwm, thiab carbidopa. Carbidopa pab ua kom levodopa tsis zoo, zoo li xeev siab, los ntawm mob heev.

Akinesia hauv PD tuaj yeem tshwm sim vim yog tsis muaj dopamine. Koj lub hlwb tsim dopamine thiab dhau mus rau hauv koj lub cev los ntawm cov neurons. Levodopa pab kho akinesia thiab lwm cov tsos mob PD vim tias koj lub hlwb hloov nws mus rau hauv dopamine. Tom qab ntawd nws tuaj yeem nqa mus rau hauv koj lub cev kom pab txhawm rau ua kom cov leeg mob ntawm akinesia thiab cov tics thiab tshee ntawm lwm cov tsos mob PD.

Levodopa thiab carbidopa tuaj yeem cuam tshuam nrog lwm cov tshuaj noj thiab muaj qee qhov kev phiv loj heev. Tham nrog koj tus kws kho mob txog qhov kev kho no yuav cuam tshuam li cas rau koj ua ntej koj pib noj cov tshuaj no.

MAO-B inhibitors tseem yuav pab nres dopamine los ntawm kev ua kom tsis zoo los ntawm koj lub cev cov enzymes. Qhov no kuj nce dopamine uas muaj los tawm tsam akinesia thiab qeeb ntawm PD.

Cov tshuaj tsis yog ib txwm muaj txiaj ntsig kho tus mob akinesia uas tshwm sim los ntawm PSP. Cov tshuaj tiv thaiv kev ntxhov siab tuaj yeem pab txo cov mob akinesia thiab cov tsos mob tsis zoo uas tuaj yeem tshwm sim los ntawm PSP. Kev txhaj tshuaj tiv thaiv botulinum tseem tuaj yeem pab daws cov tsos mob xws li ua kom tawv muag kaw qhov tsis pom tseeb (blepharospasm).

Implantable stimulators

Yog tias cov qauv tshuaj tau hnav tawm sai dua lossis tsis muaj qhov xav tau ntawm lub akinesia, cov kws kho mob tuaj yeem sab laj txog qhov ua tau phais mob electrodes los txhawb cov chaw txav mus los. Cov kev kho mob no pab nrog cov tsos mob hauv ntau cov mob ntau dua. Qhov no hu ua kev sib sib zog nqus ntawm lub hlwb. Nws yog txheej txheem siv ntau dua hauv PD.

Muaj qhov zoo thiab qhov txwv. Tham nrog koj tus kws kho mob seb lawv puas xav tau kev kho mob no rau koj.

Tus-dhau-lub khw

Akinesia tuaj yeem ua rau mob thiab mob txhav, thiab noj tshuaj rau PD lossis PSP tuaj yeem ua rau mob thiab tsis xis nyob. Kev noj tshuaj kom tsis txhob noj tshuaj, xws li tshuaj nonsteroidal anti-inflammatory (NSAIDs) zoo li ibuprofen thiab acetaminophen tuaj yeem pab txo qee qhov mob uas PD, PSP, lossis lawv cov tshuaj txuam nrog tuaj yeem ua rau.

Lwm txoj kev kho mob thiab kho tsev

Kev tawm dag zog tsis tu ncua tuaj yeem pab koj txo qis qhov mob thiab tsis xis nyob uas tuaj yeem tshwm sim nrog akinesia thiab lwm yam kev ua haujlwm ntawm lub cev uas tuaj yeem yog los ntawm PD lossis PSP. Tham nrog koj tus kws kho mob lossis tus kws kho mob lub cev txog kev tsim lub tswv yim ua kom ib ce muaj kev nyab xeeb thiab nyab xeeb rau koj nyob ntawm koj cov tsos mob thiab kev loj hlob ntawm akinesia. Nco ntsoov tias koj tsis txhob saib koj tus kheej hnyav tshaj lossis poob thaum ua kev tawm dag zog yog qhov tseem ceeb. Ua yoga los yog tai chi, uas pab ncab koj cov leeg, tuaj yeem pab qeeb kev loj hlob ntawm akinesia. Kev tawm dag zog tau pom tias ua kom lub zog poob qis hauv PD.

Noj coenzyme Q10 rau ntau lub hlis tuaj yeem pab koj yog tias koj nyob hauv theem ntxov ntawm PD lossis PSP. Noj cov khoom noj uas muaj fiber ntau thiab haus dej kom ntau (tsawg kawg 64 ooj ib hnub) tuaj yeem pab koj cov tsos mob kom tsawg.

Cov kev kho mob uas pab ua kom koj cov leeg mob so, xws li zaws thiab acupuncture, kuj tuaj yeem txo cov tsos mob ntawm PD thiab PSP. Kev ua si los yog ua cov kev ua si uas ua kom koj lub zog txaus siab, xws li mloog suab paj nruag lossis tha xim, tuaj yeem pab txo qis ntawm akinesia thiab pab koj tuav tswj koj cov leeg.

Cov ua rau thiab txaus ntshai

Akinesia uas tshwm sim los ntawm PD thiab PSP tsis ib txwm muaj qhov ua rau pom tseeb vim tias cov xwm txheej no tuaj yeem tshwm sim los ntawm kev sib txuam ntawm koj cov caj ces thiab koj ib puag ncig. Nws tseem xav tias qhov nqaij ntawm cov nqaij hauv koj lub hlwb hu ua Lewy lub cev yuav ua rau PD. Cov protein nyob hauv cov Lewy lub cev, hu ua alpha-synuclein, kuj tseem tuaj yeem ua rau PD.

Outlook

Akinesia thiab ntau yam mob uas ua rau nws tseem tsis tau muaj txoj kev kho tau. Tab sis ntau yam tshuaj noj, kho mob, thiab hloov pauv hauv lub neej tuaj yeem pab koj ua kom koj ua ub ua no thiab muaj peev xwm ua txhua hnub.

Cov kev tshawb fawb tshiab txog PD, PSP, thiab lwm yam cuam tshuam muaj nyob rau txhua xyoo, tshwj xeeb tshaj yog nyob rau Lewy lub cev thiab lwm cov caj ces roj ntsha uas yuav ua rau cov mob no Cov kev tshawb fawb no tuaj yeem coj cov kws kho mob thiab cov kws tshawb fawb los ze zog kom nkag siab txog kev kho mob thiab kho akinesia thiab nws cov laj thawj.