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Chlorthalidone versus Hydrochlorothiazide: What Level of Evidence Is Needed to Change Practice?
Daim Duab: Chlorthalidone versus Hydrochlorothiazide: What Level of Evidence Is Needed to Change Practice?

Zoo Siab

Chlorthalidone, uas yog 'ntsiav tshuaj dej,' yog siv los kho mob ntshav siab thiab tso dej tawm los ntawm ntau yam mob, suav nrog mob plawv. Nws ua rau lub raum rhuav tshem cov dej tsis suav thiab ntsev los ntawm lub cev mus rau hauv cov zis.

Cov tshuaj no qee zaum sau tseg rau lwm qhov kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Chlorthalidone los ua ib ntsiav tshuaj los noj ntawm qhov ncauj. Nws feem ntau yog noj ib zaug ib hnub lossis txhua lwm hnub tom qab noj mov, nyiam noj tshais. Nws yog qhov zoo tshaj rau noj cov tshuaj no thaum sawv ntxov kom tsis txhob mus pw hauv chav dej thaum hmo ntuj. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj chlorthalidone raws nraim cov lus qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Chlorthalidone tswj hwm ntshav siab tab sis nws tsis kho. Noj cov tshuaj chlorthalidone txuas ntxiv txawm tias koj tus kheej yuav xis nyob. Tsis txhob tsum noj chlorthalidone tsis tham nrog koj tus kws kho mob.


Chlorthalidone kuj tseem siv tau los kho cov neeg mob ntshav qab zib insipidus thiab qee qhov kev cuam tshuam electrolyte thiab tiv thaiv lub raum pob zeb hauv cov neeg mob uas muaj calcium ntau nyob hauv lawv cov ntshav. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo uas yuav siv cov tshuaj no rau koj tus mob.

Ua ntej noj chlorthalidone,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau chlorthalidone, tshuaj sulfa, lossis lwm yam tshuaj.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov ntawv uas tsis yog kws kho mob koj noj, tshwj xeeb tshaj yog lwm yam tshuaj rau ntshav siab, tshuaj tiv thaiv mob xws li ibuprofen (Motrin, Nuprin) lossis naproxen (Aleve), corticosteroids (piv txwv li, prednisone), lithium (Eskalith , Lithobid), tshuaj rau ntshav qab zib, probenecid (Benemid), thiab vitamins. Yog tias koj tseem noj tshuaj cholestyramine lossis colestipol, noj tsawg kawg 1 teev tom qab chlorthalidone.
  • qhia rau koj tus kws kho mob yog tias koj tau lossis tau muaj ntshav qab zib, mob gout, lossis raum, mob siab, mob qog, lossis kab mob parathyroid.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj chlorthalidone, hu rau koj tus kws kho mob tam sim ntawd.
  • yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav tias koj noj chlorthalidone.
  • koj yuav tsum paub tias cov tshuaj no yuav ua rau koj nkees nkees. Tsis txhob tsav tsheb los sis siv lub tshuab ua haujlwm kom txog thaum koj paub tias cov tshuaj no cuam tshuam rau koj li cas.
  • Nco ntsoov tias dej cawv tuaj yeem ntxiv rau kev haus dej haus cawv los ntawm cov tshuaj no.
  • npaj ua kom tsis txhob muaj qhov phom sij lossis tsis haum rau lub hnub ci thiab hnav khaub ncaws tiv thaiv, tsom iav, thiab tshuaj pleev thaiv hnub. Chlorthalidone yuav ua rau koj cov tawv nqaij tiv tshav ntuj.

Ua raws li koj tus kws kho mob qhia. Lawv yuav suav nrog kev ua qoj ib ce txhua hnub los yog noj ntsev los yog noj ntsev tsawg, cov khoom ntxiv cov poov tshuaj, thiab cov khoom noj ntau ntxiv (xws li tsawb, prunes, raisins, thiab kua txiv kab ntxwv) hauv koj cov zaub mov noj.


Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav txog sijhawm rau koj cov tshuaj txuas ntxiv, hla cov koob tshuaj ploj thiab txuas ntxiv koj cov sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Nquag tso zis yuav tsum ploj mus tom qab koj siv cov tshuaj chlorthalidone li ob peb asthiv.

Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • leeg tsis muaj zog
  • kiv taub hau
  • cramps
  • kev nqhis dej
  • mob plab
  • mob plab
  • ntuav
  • zawv plab
  • tsis qab los noj mov
  • mob taub hau
  • plaub hau poob

Yog tias koj muaj cov tsos mob nram qab no, hu rau koj tus kws kho mob tam sim ntawd:

  • mob caj pas nrog kub taub hau
  • ntshav txawv lossis doog ntshav
  • cov tawv nqaij ua pob khaus tawv nrog tev tawv nqaij
  • ua pa nyuaj lossis nqos

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).


Khaws cov tshuaj no rau hauv lub thauv nws tuaj nrog hauv, kaw kom nruj thiab ncav cuag cov menyuam yaus. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help.Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj cov ntshav siab yuav tsum kuaj xyuas tsis tu ncua, thiab kuaj ntshav yuav tsum ua qee zaus.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Hygroton®
  • Thalitone®
  • Pob Zeb® (uas muaj Chlorthalidone, Clonidine)
  • Edarbyclor® (muaj Azilsartan, Chlorthalidone)
  • Lopressidone® (muaj Chlorthalidone, Metoprolol)
  • Ntxawg lauj® (muaj cov tshuaj Chlorthalidone, Reserpine)
  • Tenoretic® (uas muaj Atenolol, Chlorthalidone)

Cov khoom muaj npe khoom no tsis nyob rau ntawm kev ua lag luam. Muaj lwm cov kev xaiv uas siv tau.

Kawg Kho - 06/15/2017

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