Avatrombopag

Zoo Siab

• Ua ntej noj avatrombopag,
• Avatrombopag tuaj yeem ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no hu rau koj tus kws kho mob:
• Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

Avatrombopag yog siv los kho tus mob thrombocytopenia (ntshav tsawg ntawm cov ntshav [yuav tsum muaj ntshav txhaws]) rau cov neeg muaj mob siab (mus tsis tu ncua) mob siab uas tau teem sijhawm mus kho mob lossis kho hniav los pab tiv thaiv kom tsis txhob los ntshav. Nws kuj tseem siv los kho tus mob thrombocytopenia rau cov neeg muaj lub cev tsis muaj zog tiv thaiv kab mob (thrombocytopenia) (ITP; ib qho kev mob uas tsis tu ncua uas yuav ua rau nqaij doog lossis ntshav tawm vim tsis muaj ntshav ntau hauv cov ntshav) uas tsis pab nrog lwm qhov kev kho mob. Avatrombopag yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua thrombopoietin (TPO) receptor agonists. Nws ua haujlwm los ntawm kev ua kom lub cev tsim cov platelets ntau.

Avatrombopag los ua ib ntsiav tshuaj noj ntawm qhov ncauj. Txog kev kho mob ntawm thrombocytopenia hauv cov neeg muaj kab mob siab ntev uas tau teem sijhawm muaj txheej txheem, nws ib txwm noj nrog zaub mov ib hnub ib zaug rau 5 hnub, pib 10 mus rau 13 hnub ua ntej txoj kev. Rau kev kho mob ntawm thrombocytopenia hauv cov neeg nrog ITP, feem ntau yog noj ib hnub nrog zaub mov kom ntev li ntev tau qhia. Siv avatrombopag nyob rau tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj avatrombopag raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj avatrombopag,

• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj ua xua nrog avatrombopag, lwm yam tshuaj, lossis lwm yam tshuaj hauv avatrombopag ntsiav tshuaj. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txhua yam ntawm cov hauv qab no: amiodarone (Nexterone, Pacerone); aprepitant (Hloov Kho); qee yam antifungals xws li fluconazole, itraconazole (Onmel, Sporanox), ketoconazole, lossis voriconazole (Vfend); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); clarithromycin (Biaxin, hauv Prevpac); diltiazem (Cardizem, Cartia, Diltzac, Taztia); enzalutamide (Xtandi); erythromycin (EES, Erythrocin, lwm tus; qee yam tshuaj los kho HIV xws li efavirenz (Sustiva, hauv Atripla), indinavir (Crixivan), nelfinavir (Viracept), lossis nevirapine (Viramune); phenobarbital; phenytoin (Dilantin, Phenytek) Mycobutin); rifampin (Rifadin, Rimactane, hauv Rifamate, hauv Rifater); ritonavir (Norvir, hauv Kaletra, lwm tus), lossis saquinavir (Invirase); nefazodone; thiab verapamil (Calan, Covera, Verelan). nrog avatrombopag, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias cov tshuaj tsis tshwm hauv cov npe no.
• qhia koj tus kws kho mob tias yam tshuaj ntsuab koj noj, tshwj xeeb tshaj yog St. John wort.
• qhia koj tus kws kho mob yog tias koj tau ua lossis tau muaj ntshav txhaws, lossis mob caj ces uas tuaj yeem ua rau ntshav txhaws.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub, lossis npaj yuav cev xeeb tub. Yog tias koj cev xeeb tub thaum noj avatrombopag, hu rau koj tus kws kho mob.
• qhia rau koj tus kws kho mob yog tias koj pub mis niam rau menyuam. Koj tus kws kho mob yuav qhia koj kom tsis txhob pub mis niam rau lub sijhawm kho thiab 2 lub lis piam tom qab koj zaum kawg.

Tsis txhob noj txiv kab ntxwv qaub lossis haus cov txiv kab ntxwv kua txiv thaum siv cov tshuaj no.

Yog tias koj noj avatrombopag los kho tus mob thrombocytopenia ua ntej ib txoj kev kho mob, noj cov koob tshuaj uas ploj lawm thaum koj nco qab. Yog tias nws yuav luag txog sijhawm rau koob tshuaj ntxiv, hla cov koob tshuaj uas tsis nco qab thiab ua ntxiv rau koj lub sijhawm noj tshuaj, tab sis nco ntsoov ua kom tag nrho cov tshuaj (txawm tias lawv tsis noj 5 hnub hauv ib kab). Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Yog tias koj noj avatrombopag los kho kev tiv thaiv kab mob ntsws tsis muaj zog, noj cov tshuaj uas ploj lawm sai li sai tau thaum koj nco qab. Yog tias nws yuav luag txog rau kev noj tshuaj ntxiv, hla cov tshuaj tsis nco qab thiab txuas ntxiv rau koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Avatrombopag tuaj yeem ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• nkees heev
• mob taub hau
• ntswg los sis pos hniav los ntshav
• mob tej pob txha

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no hu rau koj tus kws kho mob:

• o o, mob, liab, lossis ceg nyuag
• txog siav ua pa, kub ib ce, hnoos, mob hauv siab, lossis plawv dhia ceev
• mob plab lossis rhiab
• o tes lossis taw

Avatrombopag tuaj yeem ua rau lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

• o o, mob, ceg liab lossis nruj ceg
• txog siav ua pa, hnoos, mob hauv siab, plawv dhia ceev
• mob plab lossis rhiab

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav txiav txim qee yam kev kuaj sim ua ntej koj pib kev kho mob los txiav txim siab koj qhov avatrombopag thiab hnub ntawm txheej txheem no.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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