Infliximab Txhaj Tshuaj

Zoo Siab

• Infliximab txhaj tshuaj yog siv los daws cov tsos mob ntawm qee qhov kev tiv thaiv kabmob (mob uas lub cev tiv thaiv tsis muaj mob ntawm lub cev thiab ua rau mob, o, thiab puas tsuaj) suav nrog:
• Ua ntej siv cov khoom lag luam infliximab txhaj tshuaj,
• Infliximab txhaj tshuaj yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Cov tsos mob hauv qab no yog qhov tsis tshua pom tshwm sim, tab sis yog tias koj ntsib ib qho twg ntawm lawv, lossis cov uas tau teev tseg rau hauv cov CEEB TOOM TSEEM CEEB los yog TSHWJ XEEB Tshwj xeeb, hu rau koj tus kws kho mob:

Infliximab txhaj tshuaj, infliximab-dyyb txhaj, thiab infliximab-abda txhaj tshuaj yog cov tshuaj lom (cov tshuaj ua los ntawm cov kab mob muaj sia). Biosimilar infliximab-dyyb txhaj tshuaj thiab infliximab-abda txhaj tshuaj zoo heev rau kev txhaj tshuaj infliximab thiab ua haujlwm zoo ib yam li kev txhaj tshuaj infliximab hauv lub cev. Yog li, lub sijhawm cov tshuaj tiv thaiv kab mob infliximab yuav siv los sawv cev rau cov tshuaj no hauv kev sib tham no.

Infliximab txhaj tshuaj yuav ua rau koj txo qis kev muaj peev xwm los tawm tsam kev sib kis thiab nce qhov kev pheej hmoo tias koj yuav kis tau tus mob hnyav, suav nrog kev kis kab mob hnyav, kab mob, lossis kab mob kis uas yuav kis thoob lub cev. Cov mob no yuav tsum tau mus kho hauv tsev kho mob thiab tuaj yeem ua rau tuag taus. Qhia rau koj tus kws kho mob yog tias koj nquag kis ib hom kev kis mob lossis yog koj xav tias koj tuaj yeem muaj ib yam kabmob kis tamsis no. Qhov no suav nrog kev kis mob me me (xws li qhib qhov ncauj lossis qhov txhab), muaj kev kis tus mob thiab mus (xws li mob tawm) thiab mob ntev uas tsis ploj. Thiab qhia koj tus kws kho mob yog tias koj muaj ntshav qab zib lossis ib qho mob uas cuam tshuam rau koj lub cev tiv thaiv kab mob thiab yog tias koj nyob lossis tau nyob hauv thaj chaw xws li Ohio lossis Mississippi hav dej nyob qhov twg cov muaj mob fungal ntau dua. Nug koj tus kws kho mob yog tias koj tsis paub tias puas muaj kev kis kab mob ntxiv rau ntawm koj thaj chaw. Kuj qhia koj tus kws kho mob yog tias koj tau noj tshuaj uas txo qis kev ua haujlwm ntawm lub cev tsis muaj zog xws li abatacept (Orencia); anakinra (Kineret); methotrexate (Otrexup, Rasuvo, Trexall, Xatmep); cov tshuaj steroids xws li dexamethasone, methylprednisolone (Medrol), prednisolone (Orapred ODT, Pediapred, Prelone), lossis prednisone; los yog tocilizumab (Actemra).

Koj tus kws kho mob yuav soj ntsuam koj kom pom cov tsos mob ntawm lub sijhawm thiab tsis ntev tom qab kho koj tus mob. Yog tias koj muaj ib qho ntawm cov tsos mob nram qab no ua ntej koj pib kho koj lossis yog tias koj pom muaj cov tsos mob hauv qab no thaum lossis tom qab kho koj tus mob tas, hu rau koj tus kws kho mob tam sim ntawd: tsis muaj zog; hws; ua pa nyuaj; mob caj pas; hnoos; hnoos tau ntshav dhau los; ua npaws; nkees heev; cov tsos mob khaub thuas zoo li mob khaub thuas; sov, liab, lossis tawv nqaij mob; zawv plab; mob plab; lossis lwm cov cim ntawm kev kis mob.

Tej zaum koj yuav kis mob ntsws (TB, mob ntsws hnyav) lossis kab mob siab B (kab mob uas cuam tshuam rau daim siab) tab sis tsis muaj cov tsos mob tshwm sim. Hauv qhov no, infliximab txhaj tshuaj yuav ua rau muaj kev pheej hmoo ntxiv tias koj tus mob yuav kis hnyav dua thiab koj yuav tsim cov tsos mob. Koj tus kws kho mob yuav soj ntsuam daim tawv nqaij seb koj puas muaj tus kab mob TB tsis tsaug zog thiab tuaj yeem yuav kuaj ntshav seb koj puas muaj tus kab mob siab B tsis tsaug zog. Yog tias tsim nyog, koj tus kws kho mob yuav muab tshuaj rau koj los kho tus mob no ua ntej koj pib siv cov tshuaj infliximab txhaj tshuaj. Qhia koj tus kws kho mob yog tias koj tau lossis muaj ib txwm muaj mob ntsws TB, yog tias koj tau nyob lossis mus xyuas ib qho chaw muaj tus kabmob TB, lossis yog koj tau nyob nrog ib tus neeg mob TB. Yog tias koj muaj cov tsos mob li qhia hauv qab no ntawm TB, lossis yog tias koj muaj ib qho ntawm cov tsos mob no thaum kho koj tus mob, hu rau koj tus kws kho mob tam sim ntawd: hnoos, yuag, poob ntawm cov leeg nqaij, kub taub hau, lossis tawm hws yav hmo ntuj. Kuj hu rau koj tus kws kho mob tam sim ntawd yog tias koj muaj ib qho ntawm cov tsos mob ntawm tus kab mob siab B lossis yog tias koj muaj ib qho ntawm cov tsos mob no thaum lossis tom qab kho koj tus kheej: nkees ntau dhau, txhaws tawv nqaij lossis qhov muag, tsis qab los noj mov, xeev siab lossis ntuav, mob nqaij, tso zis dub, tso quav ua paug plob tsis so tswj, ua npaws, ua daus no, mob plab, lossis tawm pob.

Qee tus menyuam yaus, cov tub ntxhais hluas, thiab cov neeg laus hluas uas tau txais kev txhaj tshuaj tiv thaiv kab mob los yog cov tshuaj zoo sib xws tau tsim cov mob qog nqaij hlav loj lossis tuag taus xws li mob qog nqaij hlav (mob qog nqaij hlav uas pib hauv cov hlwb los tiv thaiv kev sib kis). Qee tus menyuam hluas thiab cov tub ntxhais hluas lub hnub nyoog laus uas tau noj cov tshuaj infliximab lossis cov tshuaj zoo sib xws tau tsim cov kab mob hepatosplenic T-cell lymphoma (HSTCL), uas yog hom mob cancer uas feem ntau ua rau tuag nyob rau lub sijhawm luv luv.Feem ntau ntawm cov neeg uas tsim tus mob HSTCL tau raug kho rau Crohn's mob (ib qho mob uas lub cev ua rau mob rau lub plab zom mov, ua rau mob, raws plab, poob phaus, thiab kub cev) lossis mob plab ua paug (mob uas ua rau o thiab ua paug hauv ob sab phlu ntawm txoj hnyuv [plab hnyuv loj] thiab lub qhov quav) nrog cov khoom lag luam infliximab txhaj tshuaj lossis cov tshuaj zoo ib yam nrog rau lwm cov tshuaj hu ua azathioprine (Azasan, Imuran) lossis 6-mercaptopurine (Purinethol, Purixan). Qhia koj tus menyuam tus kws kho mob yog tias koj tus menyuam tau muaj mob qog ntshav ib yam. Yog tias koj tus menyuam muaj cov tsos mob no thaum kho nws tus mob, hu rau nws tus kws kho mob tam sim ntawd: qhov kev ua kom yuag; cov qog o nyob ntawm lub caj dab, tsis txaus ntseeg, lossis puab tais; lossis yooj yim doog ntshav lossis los ntshav. Tham nrog koj tus menyuam tus kws kho mob txog cov kev pheej hmoo ntawm kev muab ib yam tshuaj txhaj infliximab rau koj tus menyuam.

Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia txog cov neeg mob rau koj (phau Ntawv Qhia Txog Tshuaj Kho Mob) thaum koj pib kho nrog ib yam tshuaj infliximab txhaj tshuaj thiab txhua zaus koj tau txais cov tshuaj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib tau Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) lub vev xaib (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) lossis cov chaw tsim tshuaj paus lub vev xaib kom tau txais Kev Qhia Tshuaj.

Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev siv cov tshuaj tiv thaiv kab mob infliximab.

Infliximab txhaj tshuaj yog siv los daws cov tsos mob ntawm qee qhov kev tiv thaiv kabmob (mob uas lub cev tiv thaiv tsis muaj mob ntawm lub cev thiab ua rau mob, o, thiab puas tsuaj) suav nrog:

• rheumatoid kev mob caj dab (ib qho mob uas lub cev tawm tsam nws cov pob qij txha, ua rau mob, o, thiab tsis ua haujlwm) uas tseem raug kho nrog methotrexate (Rheumatrex, Trexall),
• Crohn's mob (ib qho mob uas lub cev tawm tsam lub plab zom mov, ua rau mob, raws plab, yuag, thiab kub taub hau) hauv cov neeg laus thiab menyuam hnub nyoog 6 xyoo lossis laus dua uas tsis zoo dua thaum kho nrog lwm cov tshuaj,
• ulcerative colitis (mob uas ua rau o thiab mob rau sab hauv txoj hnyuv loj) hauv cov neeg laus thiab cov menyuam hnub nyoog 6 xyoo lossis laus dua uas tsis tau zoo dua thaum kho nrog lwm cov tshuaj,
• ankylosing spondylitis (ib qho mob uas lub cev tawm tsam cov pob qij txha thiab lwm qhov chaw ua rau mob thiab mob pob txha),
• plaque psoriasis (mob tawv nqaij uas liab, daim tawv thaj ua rau thaj chaw ntawm lub cev) rau cov neeg laus thaum muaj lwm yam kev kho mob kom tsis tshua zoo,
• thiab mob caj dab psoriatic (ib qho mob uas ua rau mob sib koom tes thiab o thiab ua rau ntawm daim tawv nqaij).

Infliximab txhaj tshuaj yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua qog necrosis factor-alpha (TNF-alpha) inhibitors. Lawv ua haujlwm los ntawm kev thaiv qhov kev txiav txim ntawm TNF-alpha, uas yog ib yam khoom hauv lub cev uas ua rau muaj mob.

Infliximab txhaj tshuaj tuaj ua cov hmoov uas tov nrog cov dej tsis huv thiab muab tshuaj rau hauv ntshav (los rau hauv cov leeg ntshav) los ntawm kws kho mob lossis kws saib xyuas neeg mob. Nws ib txwm muab rau hauv kws kho mob lub chaw haujlwm ib zaug txhua 2 rau 8 asthiv, ntau zaus thaum pib kho thiab tsawg dua thaum koj kho mob tas mus li. Nws yuav siv li 2 teev rau koj kom koj tau txais tag nrho koj cov koob tshuaj infliximab, cov khoom lag luam txhaj tshuaj.

Infliximab txhaj tshuaj yuav ua rau muaj kev phiv tshuaj ntau ntxiv, suav nrog kev ua xua thaum lub sijhawm ntawd thiab tom qab 2 teev tom qab. Tus kws kho mob lossis tus nais maum yuav saib xyuas koj lub sijhawm no kom ntseeg tau tias koj tsis muaj qhov kev txhaum fab hnyav rau cov tshuaj. Koj tuaj yeem raug muab lwm cov tshuaj los kho lossis tiv thaiv kev tsis haum rau qhov khoom uas txhaj rau mob infliximab. Qhia rau koj tus kws kho mob lossis tus nais maum yog tias koj pom muaj cov tsos mob hauv qab no thaum lub sijhawm lossis tom qab koj mob: ua pob; khaus; o ntawm lub ntsej muag, qhov muag, qhov ncauj, caj pas, nplaig, daim di ncauj, tes, taw, pob taws, lossis ceg qis; ua pa nyuaj lossis nqos; dej ntws; kiv taub hau; tsaus muag; ua npaws; ua daus no; qaug dab peg; tsis pom kev zoo; thiab mob hauv siab.

Infliximab txhaj tshuaj yuav pab tswj koj tus mob, tab sis lawv yuav tsis kho koj tus mob. Koj tus kws kho mob yuav saib xyuas koj kom zoo saib seb cov tshuaj txhaj infliximab zoo li cas rau koj. Yog tias koj muaj mob rheumatoid mob caj dab lossis Crohn's mob, koj tus kws kho mob yuav nce cov tshuaj uas koj tau txais, yog tias xav tau. Yog tias koj muaj Crohn's kab mob thiab koj tus mob tseem tsis tau zoo tom qab 14 lub lis piam, koj tus kws kho mob yuav tsum tsis kho koj nrog tshuaj infliximab txhaj tshuaj. Nws yog ib qho tseem ceeb uas yuav tau qhia koj tus kws kho mob seb koj xav li cas thaum kho koj tus mob.

Infliximab txhaj tshuaj kuj tseem siv qee lub sijhawm los kho Behcet's syndrome (mob rau hauv lub qhov ncauj thiab ntawm caj ces thiab o ntawm ntau qhov chaw ntawm lub cev). Tham nrog koj tus kws kho mob txog cov kev pheej hmoo uas yuav siv cov tshuaj no rau koj tus mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej siv cov khoom lag luam infliximab txhaj tshuaj,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau infliximab, infliximab-axxq, infliximab-dyyb, infliximab-abda, ib yam tshuaj twg ua los ntawm murine (nas) cov protein, lwm yam tshuaj, lossis ib yam ntawm cov khoom xyaw hauv infliximab, infliximab-dyyb, lossis infliximab-abda txhaj tshuaj. Nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj tsis paub tias yam tshuaj uas koj muaj kev fab tshuaj yog ua los ntawm cov protein ua haujlwm. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog cov tshuaj teev tseg rau hauv seem TSEEM CEEB HEEV thiab ib qho twg ntawm cov hauv qab no: anticoagulants (ntshav cov ntshav) xws li warfarin (Coumadin), cyclosporine (Gengraf, Neoral, Sandimmune), thiab theophylline (Elixophyllin, Theo-24, Theochron) Cov. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia rau koj tus kws kho mob yog tias koj tau lossis muaj lub siab tsis ua haujlwm sai (mob lub siab tsis tuaj yeem tso ntshav txaus rau lwm qhov ntawm lub cev). Koj tus kws kho mob yuav qhia koj kom tsis txhob siv cov khoom lag luam infliximab.
• qhia rau koj tus kws kho mob yog tias koj tau kho mob phototherapy (ib qho kev kho mob rau tus mob psoriasis uas cuam tshuam nrog rau daim tawv nqaij ua rau lub teeb ci ntsa iab) thiab yog tias koj muaj lossis puas tau muaj mob ua mob rau koj cov leeg hlwb, xws li ntau yam sclerosis (MS; poob ntawm kev sib koom tes, kev ua kom tsis muaj zog, thiab loog vim yog lub paj puas), Guillain-Barre syndrome (tsis muaj zog, mob muag, thiab muaj peev xwm ua kom tuag tes tuag taw vim yog poob ntawm lub paj hlwb tam sim) lossis optic neuritis (mob rau ntawm cov hlab xa xov ntawm lub qhov muag mus rau lub hlwb); loog, mob lossis caj dab hauv ib qho ntawm koj lub cev; qaug dab peg; kab mob ntsws uas tsis paub mob (COPD; ib pawg kab mob uas cuam tshuam rau lub ntsws thiab cov hlab pa); ib hom mob cancer; teeb meem los ntshav lossis kab mob uas cuam tshuam koj cov ntshav; lossis kab mob plawv.
• qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum siv cov tshuaj infliximab txhaj tshuaj, hu rau koj tus kws kho mob. Yog tias koj siv cov koob tshuaj infliximab thaum koj cev xeeb tub, nco ntsoov nrog koj tus kws kho mob tham txog qhov no tom qab koj yug los. Tej zaum koj tus menyuam yuav tsum tau txais kev txhaj tshuaj tiv thiav dua li ib txwm.
• yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav tias koj siv cov khoom lag luam infliximab.
• qhia rau koj tus kws kho mob yog tias koj nyuam qhuav tau txais tshuaj tiv thaiv. Thiab nug koj tus kws kho mob seb koj puas yuav tau txhaj tshuaj tiv thaiv kab mob. Tsis muaj kev txhaj tshuaj yam tsis tas tham nrog koj tus kws kho mob. Nws yog ib qho tseem ceeb tias cov neeg laus thiab menyuam yaus tau txais kev txhaj tshuaj tiv thaiv txhua hnub nyoog ua ntej pib kho nrog infliximab.
• koj yuav tsum paub tias koj tuaj yeem ncua tshuaj tiv thaiv qeeb 3 mus rau 12 hnub tom qab koj tau txais cov khoom lag luam infliximab. Qhia rau koj tus kws kho mob yog tias koj pom muaj cov tsos mob hauv qab no ob peb hnub lossis ntev dua tom qab kev kho mob: mob leeg lossis mob pob txha; ua npaws; ua pob; khaus; khaus; o ntawm tes, lub ntsej muag, lossis daim di ncauj; teeb meem nqos; mob caj pas; thiab mob taub hau.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Infliximab txhaj tshuaj yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• xeev siab
• Kev mob siab
• mob taub hau
• los ntswg
• dawb plia nyob rau hauv lub qhov ncauj
• qhov chaw mos khaus, hlawv, thiab mob, lossis lwm yam tsos mob ntawm poov xab mob
• yaug

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Cov tsos mob hauv qab no yog qhov tsis tshua pom tshwm sim, tab sis yog tias koj ntsib ib qho twg ntawm lawv, lossis cov uas tau teev tseg rau hauv cov CEEB TOOM TSEEM CEEB los yog TSHWJ XEEB Tshwj xeeb, hu rau koj tus kws kho mob:

• ib yam pob khaus, suav nrog ua pob rau ntawm ob sab plhu lossis sab caj npab uas tau txais los ntawm lub hnub
• mob hauv siab
• lub plawv dhia tsis xwm yeem
• mob mob ntawm caj npab, nraub qaum, caj dab, lossis puab tsaig
• mob plab
• o ntawm cov taw, pob taws, lub plab, lossis ceg qis
• nce ceeb thawj sai
• txog siav
• qhov muag plooj lossis pom kev txawv
• cia li tsis muaj zog ntawm txhais caj npab lossis txhais ceg (tshwj xeeb ntawm ib sab ntawm lub cev) lossis ntawm lub ntsej muag
• leeg mob lossis mob pob qij txha
• loog lossis tingling hauv qee qhov ntawm lub cev
• kev tsim txom dheev, hais lus tsis meej, lossis tsis nkag siab
• dheev teeb meem taug kev
• kiv tob hau lossis tsaus muag
• poob ntawm kev tshuav lossis kev sib koom tes
• dheev, mob taub hau heev
• qaug dab peg
• daj ntawm daim tawv nqaij lossis qhov muag
• cov zis dub zoo nkauj
• tsis qab los noj mov
• mob hauv sab saud hauv plab
• doog ntshav los ntshav tsis txawv
• cov ntshav nyob hauv cov quav
• daj ntseg tawv nqaij
• xim liab, khaus khaus ntsej muag lossis muaj pob hauv cov tawv nqaij

Infliximab kev txhaj tshuaj yuav ua rau koj muaj feem mob qog nqaij hlav cancer (mob qog nqaij hlav uas pib hauv hlwb uas tiv thaiv kev kis tus kab mob) thiab lwm yam qog nqaij hlav.Mus rau koj tus kws kho mob txog cov kev pheej hmoo ntawm kev tau txais cov khoom txhaj tshuaj infliximab.

Infliximab txhaj tshuaj yuav ua rau lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum siv cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Koj tus kws khomob yuav khaws cov tshuaj hauv nws lub chaw ua haujlwm.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws khomob yuav xaj qee yam kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau kev txhaj tshuaj infliximab.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Avsola^® (Infliximab-axxq)
• Inflectra^® (Infliximab-dyyb)
• Tshuas^® (Infliximab)
• Renflexis^® (Infliximab-abda)

• Los tiv thaiv qog Necrosis Qhov Tseeb-alpha
• Anti-TNF-alpha
• cA2