Immunoelectrophoresis - ntshav

Ntshav immunoelectrophoresis yog ib txoj kev sim ntsuas uas ntsuas cov protein hu ua immunoglobulins hauv cov ntshav. Immunoglobulins yog cov protein ua haujlwm ua haujlwm tiv thaiv kabmob, uas tawm tsam kev kis mob. Muaj ntau hom tshuaj tiv thaiv kab mob uas tawm tsam ntau hom kev sib kis. Qee hom tshuaj tiv thaiv immunoglobulins tuaj yeem txawv txav thiab tuaj yeem yog los ntawm mob qog nqaij hlav.

Immunoglobulins kuj tseem tuaj yeem ntsuas hauv cov zis.

Xav tau cov ntshav ntxiv.

Nws tsis muaj qhov tshwj xeeb npaj rau qhov kev ntsuas no.

Thaum cov koob tau tso rau hauv cov ntshav, qee cov neeg hnov ​​mob me ntsis. Lwm tus ho hnov ​​tus mob lossis ceg tawv xwb. Tom qab ntawd, tej zaum yuav muaj qee qhov duav lossis pob me me. Tsis ntev no ploj mus.

Qhov kev ntsuam xyuas no feem ntau siv los kuaj xyuas theem ntawm cov tshuaj tiv thaiv thaum muaj qee yam qog nqaij hlav thiab lwm yam kev ntshaus siab tuaj los yog xav tias tsam muaj.

Qhov ib txwm tshwm sim (qhov tsis zoo) txhais tau hais tias cov ntshav ntsuas tau muaj cov hom tshuaj tiv thaiv kab mob immunoglobulins. Cov theem ntawm ib hom tshuaj immunoglobulin tsis siab dua lwm qhov.

Qhov ntsuas tsis zoo yuav yog vim:

• Ntau myeloma (ib hom mob ntshav)
• Mob ntsws lymphocytic los yog Waldenström macroglobulinemia (mob qog nqaij hlav ntshav dawb)
• Amyloidosis (txhim kho cov protein txawv hauv cov nqaij thiab kabmob)
• Lymphoma (mob qog nqaij hlav)
• Raum tsis ua haujlwm
• Kab mob

Qee tus neeg muaj monoclonal immunoglobulins, tab sis tsis muaj mob qog noj ntshav. Qhov no hu ua monoclonal gammopathy ntawm qhov tsis paub qhov tseem ceeb, lossis MGUS.

Txoj kev pheej hmoo me ntsis nrog kev coj koj cov ntshav mus. Cov leeg thiab cov hlab ntsha sib txawv raws li ib tug neeg mus rau lwm qhov thiab ntawm ib sab ntawm lub cev mus rau lwm qhov. Noj ntshav los ntawm qee tus neeg yuav nyuaj dua li lwm tus.

Lwm yam kev phom sij los cuam tshuam nrog kev kos ntshav me ntsis, tab sis yuav suav nrog:

• Los ntshav ntau
• Tsaus muag lossis hnov ​​nkaus lub teeb
• Ntau cov punctures los nrhiav cov leeg ntshav
• Hematoma (ntshav ntau nyob hauv qab daim tawv nqaij)
• Kev kis tus kab mob (muaj kev pheej hmoo me me txhua lub sijhawm ntawm daim tawv tawg)

IEP - ntshiab; Immunoglobulin electrophoresis - ntshav; Gamma globulin electrophoresis; Ntshiab immunoglobulin electrophoresis; Amyloidosis - electrophoresis ntshav dej; Ntau qhov mob myeloma - ntshiab electrophoresis; Waldenström - ntshiab electrophoresis

• Kuaj ntshav

Aoyagi K, Ashihara Y, Kasahara Y. Immunoassays thiab tshuaj tiv thaiv kab mob. Hauv: McPherson RA, Pincus MR, eds. Henry's Kev Kuaj Mob thiab Kev Tswj Xyuas los ntawm Laboratory Txoj KevCov. 23rd ed. St Louis, MO: Elsevier; 2017: chaaj 44.

Kricka LJ, Park JY. Immunochemical kev kawm. Hauv: Rifai N, ed. Tietz Phau Ntawv Sau Txog Kev Siv Science Thiab Kev Kuaj Mob MolecularCov. 6 tus ed. St Louis, MO: Elsevier; 2018: chap 23.