Wilms hlav

Wilms hlav (WT) yog ib hom mob raum uas tshwm sim rau cov menyuam yaus.

WT yog hom feem ntau ua rau menyuam yaus mob raum. Qhov tseeb yog qhov ua kom mob cancer no rau feem ntau ntawm cov menyuam yaus.

Iris ploj ntawm lub qhov muag (aniridia) yog qhov yug los uas muaj qee zaum cuam tshuam nrog WT. Lwm yam mob yug los txuas rau hom mob raum muaj xws li muaj teeb meem tso zis thiab o ntawm ib sab ntawm lub cev, ib qho mob hu ua hemihypertrophy.

Nws muaj ntau dua ntawm qee cov kwvtij thiab menyuam ntxaib, uas qhia tias muaj peev xwm tshwm sim tau raws caj ces.

Tus kab mob feem ntau tshwm sim rau cov menyuam yaus hnub nyoog 3 xyoos. Ntau tshaj li 90% ntawm cov neeg tau kuaj pom ua ntej muaj hnub nyoog 10 xyoo. Muaj qee zaus, nws pom ntawm cov menyuam yaus hnub nyoog qis dua 15 xyoos, thiab cov laus.

Cov tsos mob tuaj yeem suav nrog ib qho hauv qab no:

• Mob plab
• Mob plab tsis zoo
• Cem quav
• Ua npaws
• Kev tsis xis nyob lossis qhov tsis xis nyob (malaise)
• Ntshav siab
• Nce kev loj hlob ntawm ib sab cev nkaus xwb
• Tsis qab los noj mov
• Xeev siab thiab ntuav
• O o hauv plab (mob plab hauv plab los yog loj)
• Tawm hws (thaum tsaus ntuj)
• Cov ntshav hauv cov zis (hematuria)

Tus kws kho mob yuav kuaj ib ce thiab nug txog koj tus menyuam cov tsos mob thiab keeb kwm kev kho mob. Yuav nug koj seb koj puas muaj keeb kwm mob caj dab hauv tsev neeg.

Kev kuaj mob lub cev yuav qhia pom tias lub plab nyob qhov twg. Ntshav siab kuj tseem tuaj yeem nthuav.

Kev Xeem muaj xws li:

• Mob plab hauv ultrasound
• Lub plab xoo hluav taws xob
• BUN
• Kev ntsuas hluav taws xob xoo hluav taws xob lossis CT scan
• Ua kom tiav cov ntshav suav (CBC), tej zaum yuav ua rau pom ntshav khiav ceev
• Neej Khuam Siab
• Creatinine kev tshem tawm
• CT scan ntawm lub plab mog nrog sib piv
• MRI
• Tso cov tshuaj pyelogram
• MR angiography (MRA)
• Mob Lub Hlaus
• Alkaline phosphate
• Tshuaj calcium
• Transaminases (nplooj siab enzymes)

Lwm qhov kev ntsuam xyuas xav tau los txiav txim siab yog tias qog kis mus kis mob tuaj yeem suav nrog:

• Echocardiogram
• Lub ntsws scan
• TSIAJ scan
• Raug me

Yog tias koj tus menyuam raug kuaj mob WT, tsis txhob txhov lossis thawb lub thaj tsam hauv plab. Siv kev saib xyuas thaum lub sijhawm da dej thiab tuav kom tsis txhob raug mob rau lub qog.

Thawj kauj ruam ntawm kev kho mob yog los ua tus hlav. Kev qog sau ntawv pab tus kws kho mob txiav txim siab seb tus mob cancer kis tau li cas thiab npaj rau kev kho zoo tshaj plaws. Kev phais mob kom tshem tawm cov qog yog npaj sai li sai tau. Nyob ib puag ncig cov ntaub so ntswg thiab cov plab hnyuv siab raum yuav tsum tau muab tshem tawm yog tias cov qog tau kis mus.

Kev siv hluav taws xob thiab kev siv tshuaj kho mob yuav feem ntau yuav pib tom qab kev phais mob, nyob ntawm theem ntawm qog.

Kev siv tshuaj kho mob ua ntej kev phais mob tau ua tiav rau kev tiv thaiv kev mob nyhav.

Cov menyuam yaus uas lub qog tsis kis tau tus mob muaj 90% kho nrog txoj kev kho kom zoo. Kev kuaj mob kuj tseem zoo dua rau cov menyuam yaus hnub nyoog qis dua 2 xyoos.

Cov qog yuav loj tuaj, tab sis feem ntau nyob ntawm tus kheej ntim. Kev mob tawm ntawm cov qog mus rau lub ntsws, cov qog ntshav, mob siab, pob txha, lossis paj hlwb yog qhov kev txhawj xeeb tshaj plaws.

Ntshav siab thiab lub raum puas tsuaj tuaj yeem tshwm sim los ntawm cov qog ntshav lossis nws txoj kev kho mob.

Kev tshem tawm WT ntawm ob lub raum yuav cuam tshuam rau lub raum kev ua haujlwm.

Lwm qhov teeb meem kev pheej hmoo ntawm kev kho mob mus ntev ntawm WT kuj yuav suav nrog:

• Lub plawv tsis ua hauj lwm
• Kab mob khees xaws thib ob nyob rau hauv lub cev uas muaj kev txhim kho tom qab kev kho mob cancer thawj zaug
• Qhov siab luv

Hu rau koj tus menyuam qhov chaw zov menyuam yog:

• Koj pom muaj qog hauv koj tus menyuam lub plab, ntshav hauv zis, lossis lwm tus tsos mob ntawm WT.
• Koj tus menyuam raug kho rau tus mob no thiab cov tsos mob hnyav zuj zus lossis cov tsos mob tshiab tshwm sim, feem ntau yog hnoos, mob hauv siab, poob phaus, los yog kub taub hau tas li.

Hais txog cov menyuam yaus uas muaj kev pheej hmoo siab rau WT, kev soj ntsuam siv ultrasound ntawm lub raum lossis tshuaj ntsuam cev xeeb tub yuav qhia tau.

Nephroblastoma; Lub raum mob - Wilms

• Raum anatomy
• Wilms hlav

Lub koom haum Cancer National website. Wilms mob qog thiab lwm yam kev mob qog ua ntshav (PDQ) - kev tshaj lij kho mob. www.cancer.gov/types/kidney/hp/wilms-nyuj-pdq. Hloov kho lub Rau Hli 8, 2020. Nkag mus rau Lub Yim Hli 5, 2020.

Ritchey ML, Tus Nqi NG, Shamberger RC. Kuaj mob raum mob ntsws: raum thiab adrenal. Hauv: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein UrologyCov. 12th ed. Philadelphia, PA: Elsevier; 2021: chap 53.

Weiss RH, Jaimes EA, Hu SL. Mob raum. Hauv: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner thiab Rector's RaumCov. 11th ed. Philadelphia, PA: Elsevier; 2020: chaaj 41.