Neuropathy theem nrab rau cov tshuaj

Neuropathy yog qhov raug mob rau hlab ntsha caj qaum. Cov no yog cov qab haus huv uas tsis nyob hauv hlwb los yog txha caj qaum. Neuropathy theem nrab rau kev siv yeeb tshuaj yog qhov ploj ntawm qhov tsis hnov ​​lossis txav mus rau hauv ib feem ntawm lub cev vim cov hlab ntsha puas tsuaj los ntawm kev noj qee yam tshuaj lossis cov tshuaj ua ke.

Qhov kev puas tsuaj yog tshwm sim los ntawm cov nyhuv tshuaj lom ntawm qee cov tshuaj ntawm lub qab haus huv. Muaj tej zaum yuav muaj kev puas tsuaj rau lub axon ib feem ntawm lub paj hlwb, uas cuam tshuam nrog cov phiajcim hlab ntsha. Los yog, qhov kev puas tsuaj yuav koom nrog cov myelin sheath, uas ua rau cov av axon thiab nce cov xov nrawm ntawm lub teeb liab los ntawm cov axon.

Feem ntau, ntau txoj hlab ntsha koom tes nrog (mob polyneuropathy). Qhov no feem ntau ua rau qhov kev hloov pauv tau pib uas yog pib rau sab nraud ntawm lub cev (distal) thiab txav mus rau hauv nruab nrab ntawm lub cev (kwv yees). Nws kuj tseem tuaj yeem hloov pauv, xws li tsis muaj zog. Muaj kuj tseem yuav hlawv mob.

Ntau yam tshuaj noj thiab tshuaj yeeb dej caw tuaj yeem ua rau lub siab mob hlwb. Cov piv txwv tau teev hauv qab no.

Cov tshuaj rau lub plawv lossis ntshav siab:

• Amiodarone
• Hydralazine
• Perhexiline

Tshuaj siv los tua mob cancer:

• Cisplatin
• Docetaxel
• Paclitaxel
• Suramin
• Vincristine

Cov tshuaj siv los tua kab mob:

• Chloroquine
• Dapsone
• Isoniazid (INH), siv rau kev tiv thaiv kab mob ntsws
• Cov tshuaj Metronidazole (Flagyl)
• Nitrofurantoin
• Thalidomide (siv los tua cov mob ruas)

Tshuaj siv los kho tus kab mob autoimmune:

• Etanercept (Enbrel)
• Infliximab (Remicade)
• Leflunomide (Arava)

Tshuaj siv los kho qaug dab peg:

• Carbamazepine
• Phenytoin
• Phenobarbital

Tshuaj tiv thaiv cawv:

• Disulfiram

Tshuaj los tua HIV / AIDS:

• Didanosine (Videx)
• Emtricitabine (Emtriva)
  
• Stavudine (Zerit)
• Tenofovir thiab emtricitabine (Truvada)

Lwm yam tshuaj thiab tej yam ua rau mob neuropathy yog:

• Colchicine (siv los kho mob gout)
• Disulfiram (siv los kho cawv cawv)
• Arsenic
• Kub

Cov tsos mob tuaj yeem suav nrog ib qho hauv qab no:

• Loog, poob ntawm txoj kev hnov
• Qoj ib ce, txawv txav
• Neeg tsis muaj zog
• Hlawv mob

Kev hnov ​​hnov ​​txawv txav feem ntau pib hauv taw lossis txhais tes thiab txav sab hauv.

Kev kuaj xyuas lub paj hlwb thiab lub paj hlwb yuav ua tiav.

Lwm yam kev ntsuam xyuas suav nrog:

• Kev kuaj ntshav kom paub cov qib tshuaj (txawm tias cov ntshav ib txwm nyob ntawm qee yam tshuaj yuav raug lom rau hauv cov laus lossis lwm tus neeg)
• EMG (electromyography) thiab cov kev sib tw ntawm lub paj hlwb tau soj ntsuam ntawm qhov hluav taws xob kev ua haujlwm ntawm cov leeg thiab cov leeg

Txoj kev kho yog kho raws cov tsos mob thiab mob hnyav npaum li cas. Cov tshuaj ua rau cov hlab ntsha hlwb yuav tsum nres, txo qis hauv koob tshuaj, lossis hloov mus rau lwm yam tshuaj. (Tsis txhob hloov ib yam yeeb tshuaj yam tsis tau tham nrog koj tus kws kho mob.)

Koj tus kws kho mob yuav qhia cov tshuaj hauv qab no los pab tswj qhov mob:

• Cov tshuaj yuav tom khw muag tshuaj yuav pab tau qhov mob me me (neuralgia).
• Phenytoin, carbamazepine, gabapentin, pregabalin, duloxetine, lossis tricyclic antidepressants xws li nortriptyline tuaj yeem txo qhov mob txhaws tawv nqaij uas qee tus neeg hnov.
• Opiate cov mob txo cov mob, xws li morphine lossis fentanyl, tej zaum yuav tsum tau tswj kev mob hnyav.

Tam sim no tsis muaj tshuaj uas tuaj yeem thim rov qab qhov ploj ntawm qhov hnov. Yog tias koj poob zoo, koj yuav tsum ua kev ntsuas kev nyab xeeb kom tsis txhob raug mob.

Nug koj tus kws kho mob yog tias kev tawm dag zog uas tuaj yeem pab txo koj cov tsos mob.

Coob tus neeg muaj peev xwm muaj qee yam lossis tag nrho rov qab los ua lawv li qub. Qhov kev tsis zoo no tsis yog feem ntau ua rau muaj kev phom sij txog lub neej, tab sis nws tuaj yeem tsis yooj yim lossis xiam oob qhab.

Teeb meem yuav suav nrog:

• Lub cev tsis ua haujlwm hauv tsev lossis tom tsev vim tias tsis hnov ​​dab tsi li
• Kev mob nrog tingling hauv thaj tsam ntawm lub hlab ntsha raug mob
• Kev xiam ib ce tas mus li (lossis tsis tshua muaj txav mus los) hauv thaj chaw

Hu rau koj tus kws kho mob yog tias koj tsis nco qab los yog txav ntawm ib cheeb tsam ntawm lub cev thaum noj ib qho tshuaj.

Koj tus kws kho mob yuav saib xyuas koj kev kho zoo nrog rau cov tshuaj uas tuaj yeem ua rau mob neuropathy. Lub hom phiaj yog txhawm rau tswj cov ntshav tau zoo ntawm cov tshuaj uas yuav tsum tau los tswj tus kab mob thiab nws cov tsos mob thaum tiv thaiv cov tshuaj los ntawm kev nce mus txog qib tsis zoo.

• Nruab nrab hauv lub paj hlwb thiab lub paj hlwb peripheral

Jones MR, Tso Rau Kuv, Hma J, li al. Kev quav yeeb tshuaj yuam kev mob hlwb, piav qhia. Curr Clin PharmacolCov. Lub Ib Hlis 2019. PMID: 30666914 www.ncbi.nlm.nih.gov/pubmed/30666914.

Katirji B. Kev mob tsis zoo ntawm cov hlab ntsha leeg. Hauv: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology nyob rau hauv Kev Soj NtsuamCov. 7 tus ed. Philadelphia, PA: Elsevier; 2016: chap 107.

O'Connor KDJ, Mastaglia FL. Kev quav yeeb tshuaj ua rau cov leeg poob siab. Hauv: Aminoff MJ, Josephson SA, eds. Aminoff's Neurology thiab General TshuajCov. Thib 5 ed. Waltham, MA: Elsevier Txuj Ci Tseem Ceeb; Xyoo 2014: chap 32.