Mob ntawm tus mob nephritis

Interstitial nephritis yog lub raum tsis zoo nyob rau hauv uas qhov chaw nruab nrab ntawm lub raum tubules tau o tuaj (o). Qhov no tuaj yeem tsim teeb meem rau txoj kev ntawm koj ob lub raum ua haujlwm.

Mob interstitial nephritis tej zaum yuav mob ib ntus (mob), lossis nws yuav siv sijhawm ntev (mob ntev) thiab ua rau lub sijhawm tsis zoo.

Cov mob voos ntawm interstitial nephritis feem ntau tshwm sim los ntawm kev phiv los ntawm qee cov tshuaj.

Cov hauv qab no tuaj yeem ua rau mob interstitial nephritis:

• Kev tsis haum tshuaj rau qhov quav tshuaj (mob interstitial allergic nephritis).
• Cov kab mob autoimmune, xws li kab mob antitubular hauv qab daus membrane, kab mob Kawasaki, Sjögren syndrome, mob hlwb lupus erythematosus, lossis granulomatosis nrog polyangiitis.
• Kab mob.
• Kev siv tshuaj kho mob ntev ntev xws li acetaminophen (Tylenol), tshuaj aspirin, thiab nonsteroidal anti-inflammatory drugs (NSAIDs). Qhov no yog hu ua analgesic nephropathy.
• Cov kev mob tshwm sim ntawm qee yam tshuaj tua kab mob xws li penicillin, ampicillin, methicillin, thiab sulfonamide tshuaj.
• Kev phiv rau lwm cov tshuaj xws li furosemide, thiazide diuretics, omeprazole, triamterene, thiab allopurinol.
• Muaj cov poov tshuaj me me rau hauv koj cov ntshav.
• Muaj calcium ntau lossis uric acid ntau hauv koj cov ntshav.

Interstitial nephritis tuaj yeem ua rau mob raum mob mus rau lub raum, nrog rau mob raum tsis ua haujlwm. Li ntawm ib nrab ntawm cov neeg mob, tib neeg yuav muaj tso zis tsawg dua thiab lwm cov tsos mob ntawm lub raum tsis ua haujlwm.

Cov tsos mob ntawm tus mob no yuav suav nrog:

• Cov ntshav hauv cov zis
• Ua npaws
• Tso zis ntau dua lossis tso zis ntau ntxiv
• Hloov hlwb hloov pauv (tsaug zog, tsis meej pem, tsis nco qab)
• Xeev siab, ntuav
• Pob pob
• O rau txhua qhov chaw ntawm lub cev
• Qhov hnyav nce (los ntawm khaws cov dej)

Tus kws kho mob yuav kuaj xyuas lub cev. Qhov no yuav qhia:

• Lub suab tsis zoo lossis lub plawv tsis zoo
• Ntshav siab
• Ua kua rau lub ntsws (ntsws ntsws o)

Cov kev xeem sib xws suav nrog:

• Arterial ntshav roj
• Qhia txog ntshav ntshav
• BUN thiab ntshav creatinine qib
• Ua kom tiav cov ntshav suav
• Raum raum
• Lub raum ultrasound
• Mob Lub Hlaus

Kev kho yog nyob ntawm qhov ua rau muaj teeb meem. Zam kev noj tshuaj uas ua rau tus mob no tuaj yeem txo cov tsos mob sai.

Txwv cov ntsev thiab kua dej rau hauv cov zaub mov tuaj yeem txhim kho kev o thiab ntshav siab. Txwv cov protein ntau hauv kev noj haus tuaj yeem pab tswj kev tsim cov khoom pov tseg hauv cov ntshav (azotemia), uas tuaj yeem ua rau cov tsos mob ntawm lub raum tsis ua haujlwm.

Yog tias lim ntshav yog tsim nyog, feem ntau yuav tsum tsuas yog siv sijhawm luv.

Corticosteroids lossis muaj zog cov tshuaj los tiv thaiv xws li cyclophosphamide qee zaum yuav pab tau.

Feem ntau, interstitial nephritis yog ib qho kev mob luv luv. Tsawg tsawg zaus, nws tuaj yeem ua kev puas tsuaj mus tas li, suav nrog lub raum ntev (mob) lub raum tsis ua haujlwm.

Mob raum ntu pob txha caj qaum yuav ua tau mob hnyav dua thiab yuav ua rau mob raum ntev los yog mob raum rau cov neeg laus.

Kev tiv thaiv kab mob ua haujlwm tuaj yeem tshwm sim vim tias ob lub raum tsis tuaj yeem tshem tawm cov kua qaub. Qhov kev cuam tshuam no tuaj yeem ua rau mob raum lossis mob raum tsis zoo los yog mob raum ntu kawg.

Hu rau koj tus kws kho mob yog tias koj muaj cov tsos mob ntawm mob interstitial nephritis.

Yog tias koj muaj tus mob nestritis interstitial, hu rau koj tus kws kho mob yog tias koj tau pom cov tsos mob tshiab, tshwj xeeb yog tias koj tsis tshua nco qab lossis muaj tso zis tsawg dua.

Feem ntau, kev cuam tshuam tsis tuaj yeem tiv thaiv. Kev zam lossis txo koj kev siv tshuaj uas tuaj yeem ua rau tus mob no tuaj yeem pab txo koj txoj kev pheej hmoo. Yog tias xav tau, koj tus kws kho mob yuav qhia koj txog cov tshuaj twg los txiav lossis txo qis.

Tubulointerstitial nephritis; Nephritis - interstitial; Mob nyhav ua pob txha tsis haum (ua xua) nephritis

• Raum anatomy

Neilson EG. Tubulointerstitial nephritis. Hauv: Goldman L, Schafer AI, eds. Goldman-Cecil TshuajCov. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 122.

Perazella MA, Rosner MH. Tubulointerstitial kab mob. Hauv: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner thiab Rector's RaumCov. 10 tus ed. Philadelphia, PA: Elsevier; 2020: chap 35.

Tanaka T, Nangaku M. Ntev interstitial nephritis. Hauv: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Cov Chaw Kho Mob Tshaj LojCov. 6 tus ed. Philadelphia, PA: Elsevier; 2019: chap 62.