Cholestasis

Cholestasis yog ib qho mob uas cov kua tsib los ntawm nplooj siab qeeb los yog txhaws.

Muaj ntau yam ua rau mob cholestasis.

Kev tiv thaiv mob cholestasis feem ntau tshwm sim sab nraum lub siab. Nws tuaj yeem tshwm sim los ntawm:

• Cov kua tsib ob lub qog
• Hlwv
• Qhov nqaim ntawm tus kab mob bile roj (nruj)
• Lub pob zeb nyob hauv cov hlwv bile hom
• Kev mob caj dab
• Pancreatic mob qog lossis pseudocyst
• Siab rau ntawm lub bile ducts vim tias muaj cov khoom nyob ze lossis qog nqaij hlav
• Thawj sclerosing cholangitis

Intrahepatic cholestasis tshwm sim sab hauv. Nws tuaj yeem tshwm sim los ntawm:

• Cawv muaj mob rau daim siab
• Mob Amyloidosis
• Cov kab mob ua paug hauv lub siab
• Kev pub rau cov miv ntsuav ib leeg ntshav (IV)
• Lymphoma
• Cev xeeb tub
• Thawj biliary mob kas cees
• Kab mob qog nqaij hlav cancer thawj lossis metastatic
• Thawj sclerosing cholangitis
• Sarcoidosis
• Cov mob hnyav uas tau kis los ntawm cov hlab ntshav (sepsis)
• Tub Ntshaw
• Kab mob siab

Qee hom tshuaj tuaj yeem ua rau cholestasis, suav nrog:

• Tshuaj tua kab mob, xws li ampicillin thiab lwm yam penicillins
• Cov tshuaj steroid anabolic
• Tshuaj noj tiv thaiv tsis pub muaj menyuam
• Chlorpromazine
• Cimetidine
• Estradiol
• Imipramine
• Prochlorperazine
• Terbinafine
• Tolbutamide

Cov tsos mob tuaj yeem suav nrog:

• Av nplaum lossis tawv dawb
• Tsaus zis
• Tsis taus zom tej yam khoom noj
• Khaus
• Xeev siab los ntuav
• Hnov mob sab xis rau hauv plab plab
• Daim tawv daj lossis qhov muag daj

Kev kuaj ntshav tuaj yeem pom tias koj tau nce bilirubin thiab alkaline phosphatase ntau dua.

Kev ntsuam xyuas qhov muag raug siv los kuaj xyuas tus mob no. Kev Xeem muaj xws li:

• CT scan ntawm lub plab mog
• MRI ntawm lub plab mog
• Endoscopic retrograde cholangiopancreatography (ERCP), tuaj yeem txiav txim siab ua rau muaj mob
• Ultrasound ntawm plab

Lub hauv paus ua rau cholestasis yuav tsum tau kho.

Ib tug neeg yuav kis tau zoo npaum li cas yog nyob ntawm cov kabmob ua rau tus mob. Cov pob zeb nyob hauv cov nqaj tsib feem ntau tuaj yeem tshem tawm. Qhov no tuaj yeem kho tus mob cholestasis.

Txoj hlua tuaj yeem tso rau hauv thaj chaw qhib ntawm cov kua tsib uas yog nqaim lossis thaiv los ntawm cov qog nqaij hlav.

Yog tias tus mob tshwm sim los ntawm kev siv qee yam tshuaj, nws feem ntau yuav ploj mus thaum koj tsum tsis noj qhov tshuaj ntawd.

Teeb meem yuav suav nrog:

• Zawv plab
• Lub cev tsis ua haujlwm tuaj yeem tshwm sim yog mob sepsis
• Tsis zoo nqus ntawm cov rog thiab cov roj-soluble vitamins
• Kev khaus heev
• Cov pob txha tsis muaj zog (osteomalacia) vim tias muaj cholestasis ntev heev

Hu koj tus kws kho mob yog tias koj muaj:

• Khaus uas tsis ploj mus
• Daim tawv daj lossis qhov muag daj
• Lwm cov tsos mob ntawm tus mob cholestasis

Mus txhaj tshuaj tiv thaiv kab mob siab A thiab B yog tias koj muaj pheej hmoo. Tsis txhob siv cov tshuaj yaj yeeb thiab koom nrog rab koob.

Mob siab hauv cholestasis; Cov kab mob cholestasis tsis hnyav

• Gallstones
• Gallbladder
• Gallbladder

Eaton JE, Lindor KD. Thawj chilangitis. Hauv: Feldman M, Friedman LS, Brandt LJ, eds. Stus kws kho mob thiab Fordtran lub plab zom mov thiab daim siab. 11th ed. Philadelphia, PA: Elsevier; 2021: chap 91.

Cov Fogel EL, Sherman S. Cov kab mob ntawm lub gallbladder thiab kua tsib lub raj. Hauv: Goldman L, Schafer AI, eds. Goldman-Cecil Tshuaj. 26th ed. Philadelphia, PA: Elsevier; 2020: cha 146.

Lidofsky SD. Qhov muag daj. Hauv: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger thiab Fordtran mob hnyuv thiab nplooj siab mob. 11th ed. Philadelphia, PA: Elsevier; 2021: chap 21.