TP53 Kev Kuaj Mob Raws Li Cas

Zoo Siab

• TP53 kev kuaj mob caj ces yog dab tsi?
• Nws siv rau dab tsi?
• Vim li cas kuv thiaj xav tau TP53 caj ces?
• Yuav muaj dab tsi tshwm sim thaum kuaj TP53?
• Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?
• Puas muaj kev pheej hmoo rau kev kuaj?
• Cov txiaj ntsig li cas?
• Puas muaj lwm yam ntxiv uas kuv xav paub txog qhov kev kuaj mob TP53?
• Ua tim khawv

TP53 kev kuaj mob caj ces yog dab tsi?

Qhov kuaj mob TP53 nrhiav qhov hloov pauv, paub hu ua kev hloov pauv, hauv tus gene hu ua TP53 (cov qog protein 53). Cov noob yog qhov tseem ceeb ntawm caj ces dhau los ntawm koj niam thiab koj txiv.

TP53 yog lub noob caj dab uas pab nres kev loj hlob ntawm cov qog. Nws lub npe hu ua cov tshuaj tiv thaiv qog. Cov qog noj hlav hlav qog nqaij hlav ua haujlwm zoo li tus brakes ntawm lub tsheb. Nws tso "tus tsuj" rau ntawm lub hlwb, yog li lawv tsis faib ceev nrawm. Yog tias koj muaj TP53 kev hloov pauv, cov caj ces yuav tsis tuaj yeem tswj hwm txoj kev loj hlob ntawm koj cov hlwb. Kev tswj tsis tau cell ntau tuaj yeem ua mob qog noj ntshav.

Kev hloov pauv TP53 tuaj yeem tau txais los ntawm koj niam koj txiv, lossis tau txais tom qab lub neej los ntawm ib puag ncig lossis los ntawm kev ua yuam kev uas tshwm sim hauv koj lub cev thaum faib cov cell.

• Ib qho hloov pauv tau TP53 hloov ua lub npe hu ua Li-Fraumeni syndrome.
• Li-Fraumeni syndrome yog ib qho kev mob uas tsis tshua muaj muaj caj ces ua rau koj muaj feem pheej hmoo mob qog nqaij hlav qog ntshav.
• Cov kab mob khees xaws muaj xws li mob cancer mis, mob pob txha, mob qog ntshav, thiab mob qog nqaij mos, kuj hu ua sarcomas.

Txais (tseem hu ua somatic) TP53 kev hloov pauv muaj ntau dua. Cov kev hloov tau pom muaj nyob hauv kwv yees li ib nrab ntawm txhua kis mob cancer, thiab ntau ntau hom mob cancer.

Lwm lub npe: TP53 hloov pauv, TP53 kev tshawb xyuas lub cev tag nrho, TP53 somatic hloov pauv

Nws siv rau dab tsi?

Qhov ntsuas no yog siv mus nrhiav TP53 hloov chaw. Nws tsis yog qhov kev ntsuam xyuas niaj hnub.Feem ntau nws tau muab rau cov tib neeg raws li tsev neeg keeb kwm, cov tsos mob, lossis yav dhau los kuaj mob qog noj ntshav.

Vim li cas kuv thiaj xav tau TP53 caj ces?

Koj yuav tsum kuaj TP53 yog tias:

• Koj tau txheeb pom muaj kab mob pob txha lossis nqaij mos ua ntej muaj hnub nyoog 45 xyoos
• Koj tau txheeb pom muaj, mob uantej lub hnub nyoog lub mis, mob qog rau lub hlwb, mob qog, lossis mob ntsws ua ntej muaj 46 xyoo.
• Koj tau muaj ib lossis ntau qog ua ntej 46 xyoo
• Ib lossis ntau ntawm koj tsev neeg tau txheeb pom tias Li-Fraumeni syndrome thiab / lossis tau muaj mob qog nqaij hlav ua ntej hnub nyoog 45 xyoos

Cov no yog cov cim qhia koj yuav muaj kev hloov pauv ntawm tus caj ces TP53.

Yog koj tau kuaj pom hais tias koj muaj mob qog noj ntshav thiab tsis muaj tsev neeg muaj kab mob, koj tus kws kho mob yuav xaj kuaj no mus saib seb puas muaj tus mob TP53 ua rau koj mob cancer. Kev paub seb koj puas muaj kev hloov pauv tuaj yeem pab koj tus kws kho mob npaj kho thiab kwv yees qhov tshwm sim ntawm koj tus kab mob.

Yuav muaj dab tsi tshwm sim thaum kuaj TP53?

Kev kuaj ntshav TP53 feem ntau ua rau ntshav lossis txha caj qaum.

Yog tias koj tau mus kuaj ntshav, tus kws saib xyuas kev noj qab haus huv yuav nqa ntshav los ntawm txoj hlab ntshav hauv koj txhais caj npab, siv rab koob me me. Tom qab cov koob raug tso nkag, cov ntshav me me yuav raug sau rau hauv lub khob kuaj lossis vial. Koj tuaj yeem hnov ​​me ntsis thaum cov koob nkag mus lossis tawm. Qhov no feem ntau yuav siv sijhawm tsawg dua tsib feeb.

Yog koj tau mus kuaj pob txha, koj cov txheej txheem yuav suav nrog cov theem hauv qab no:

• Koj yuav tau pw ntawm koj sab lossis koj lub plab, nyob ntawm seb cov pob txha twg yuav siv rau kev sim. Kev ntsuam xyuas mob pob txha feem ntau yog coj los ntawm lub pob txha txha.
• Koj lub cev yuav tau them nrog daim ntaub, kom tsuas yog thaj chaw ib puag ncig ntawm cov chaw sim qhia pom.
• Lub vev xaib yuav muab ntxuav nrog kev siv tshuaj tua kab mob.
• Koj yuav tau txais kev txhaj tshuaj ntawm cov lej daws. Tej zaum nws yuav plev.
• Thaum uas thaj chaw loog, lub tsev kho mob mam li coj tus qauv. Koj yuav xav tau dag heev thaum tseem muaj kev ntsuam xyuas.
• Tus kws kho mob yuav siv cov cuab yeej tshwj xeeb uas ntswj rau hauv cov pob txha kom coj tawm cov qauv ntawm cov leeg pob txha. Koj tuaj yeem hnov ​​qee qhov kev nyuab siab rau lub xaib thaum lub sijhawm coj mus kuaj.
• Tom qab sim, tus kws kho mob yuav npog cov vev xaib nrog daim ntaub qhwv.
• Npaj kom muaj ib tug neeg tsav koj mus tsev, vim tias koj yuav tau muab tshuaj tsaug zog ua ntej kev ntsuam xyuas, uas yuav ua rau koj tsaug zog.

Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?

Koj tsis tas yuav tau muaj kev npaj tshwj xeeb rau kev kuaj ntshav lossis mob pob txha.

Puas muaj kev pheej hmoo rau kev kuaj?

Txoj kev kuaj ntshav muaj feem me me. Koj yuav muaj mob me lossis doog ntshav ntawm qhov chaw tso rab koob, tab sis feem ntau cov tsos mob ploj mus sai.

Tom qab kuaj pob txha pob txha, koj yuav hnov ​​txhav txhaus lossis mob ntawm qhov chaw txhaj tshuaj. Qhov no feem ntau yuav ploj mus nyob hauv ob peb hnub. Koj tus kws kho mob yuav hais kom noj tshuaj los yog sau tshuaj kom pab daws qhov mob kom zoo.

Cov txiaj ntsig li cas?

Yog tias koj tau pom koj muaj mob Li-Fraumeni syndrome, nws tsis muaj txhais tau tias koj muaj mob qog noj ntshav, tab sis koj qhov kev pheej hmoo siab dua coob leej neeg. Tab sis yog tias koj muaj txoj kev hloov, koj tuaj yeem rhais kauj ruam los txo koj txoj kev pheej hmoo, xws li:

• Kuaj ntau dua mob khees xaws. Kab mob khees xaws raug kho ntau dua thaum pom thaum ntxov.
• Hloov ua lub neej hloov, xws li ua kom tawm dag zog ntau ntxiv thiab noj zaub mov kom noj qab haus huv
• Kev siv tshuaj tua kab mob, kev noj qee yam tshuaj, vitamins, lossis lwm yam tshuaj los txo qis kev pheej hmoo lossis ncua kev mob qog nqaij hlav.
• Tshem tawm "ntawm qhov pheej hmoo" cov ntaub so ntswg

Cov theem no yuav txawv nyob ntawm koj keeb kwm kev noj qab haus huv thiab koj tsev neeg keeb kwm.

Yog tias koj muaj mob qog noj ntshav thiab koj cov txiaj ntsig tau qhia pom tias tus mob TP53 hloov (ib qho kev hloov tau pom, tab sis koj tsis muaj keeb kwm mob caj dab lossis mob Li-Fraumeni), koj tus kws kho mob siv tau cov ntaub ntawv no los pab kwv yees seb koj tus kab mob yuav loj tuaj li cas thiab coj koj li cas kev kho mob.

Kawm paub ntau ntxiv txog cov kev sim hauv chaw soj ntsuam, cov chaw siv ntsuas, thiab nkag siab cov txiaj ntsig tau.

Puas muaj lwm yam ntxiv uas kuv xav paub txog qhov kev kuaj mob TP53?

Yog tias koj raug kuaj pom los yog xav tias koj muaj Li-Fraumeni syndrome, nws yuav pab tau hais lus rau tus kws sab laj tswv yim caj ces. Tus kws pab tswv yim txog caj ces yog tus kws tshaj lij kawm tiav los ntawm kev tshawb fawb caj ces thiab kev tshuaj ntsuam caj ces. Yog koj tseem tsis tau raug sim, tus kws pab tswv yim tuaj yeem pab koj nkag siab txog cov kev pheej hmoo thiab cov txiaj ntsig ntawm kev xeem. Yog tias koj tau sim koj, tus kws pab tswv yim tuaj yeem pab koj nkag siab qhov txiaj ntsig thiab coj koj mus txhawb cov kev pabcuam thiab lwm yam kev pabcuam.

Ua tim khawv

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Cov ntaub ntawv ntawm lub xaib no yuav tsum tsis txhob siv los hloov chaw kho mob lossis tswv yim kho mob. Hu rau kws kho mob yog tias koj muaj lus nug txog koj txoj kev noj qab haus huv.