Thalidomide
Zoo Siab
Thalidomide yog cov tshuaj siv los kho cov mob ruas uas yog kab mob los ntawm cov kab mob uas cuam tshuam rau daim tawv nqaij thiab cov leeg ntshav, ua rau tsis hnov mob, nqaij tsis muaj zog thiab tuag tes tuag taw. Tsis tas li ntawd, nws tseem pom zoo rau hauv cov neeg mob HIV thiab lupus.
Cov tshuaj no rau kev siv ntawm qhov ncauj, nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, tsuas yog siv nyob rau kev pom zoo ntawm tus kws kho mob thiab tau pom zoo tag nrho hauv kev xeeb tub thiab txwv tsis pub rau cov poj niam ntawm lub hnub nyoog yug menyuam, nruab nrab ntawm kev coj khaub ncaws thiab lub cev ntas, vim nws ua rau muaj kev cuam tshuam ntawm cov menyuam, piv txwv li qhov tsis muaj daim di ncauj, caj npab thiab txhais ceg, nce tus naj npawb ntawm cov ntiv tes, hydrocephalus lossis ua haujlwm tsis zoo ntawm lub siab, txoj hnyuv thiab raum, piv txwv. Vim li no, tus kws siv cov tshuaj no rau kev kho mob, lub sijhawm ua lub luag haujlwm yuav tsum tau kos npe.
Nqi
Cov tshuaj no yog txwv rau kev siv hauv tsev kho mob thiab tau pab dawb los ntawm tsoomfwv thiab, yog li ntawd, tsis raug muag hauv khw muag tshuaj.
Cov Khoom Qhia
Kev siv Thalidomide yog qhia rau kev kho mob:
- Mob mob ruas, uas yog kev mob ruas ntawm hom II lossis hom erythema nodosum;
- AIDS, vim tias nws txo qhov ua npaws, malaise thiab leeg tsis muaj zog:
- Lupus, mob leeg-piv nrog cov kab mob hauv lub cev, vim tias o ntau ntau.
Qhov pib ntawm kev ua ntawm cov tshuaj tuaj yeem sib txawv ntawm 2 hnub txog 3 hlis, nyob ntawm qhov ua rau muaj kev kho mob thiab tsuas yog siv tau los ntawm cov poj niam uas tsis muaj hnub nyoog yug menyuam thiab hauv cov menyuam muaj hnub nyoog 12 xyoos.
Yuav siv li cas
Kev siv cov tshuaj no hauv cov ntsiav tshuaj tsuas yog pib los ntawm kev pom zoo ntawm tus kws kho mob thiab tom qab ua raws li cov kev cai tshwj xeeb rau kev siv cov tshuaj no uas xav kom tus neeg mob kos npe rau tsab ntawv tso cai. Feem ntau, tus kws kho mob pom zoo:
- Kev kho mob mob ntsws mob tshwm sim knotty lossis hom II ntawm 100 txog 300 mg, ib hnub ib zaug, thaum mus pw lossis tsawg kawg, 1 teev tom qab noj hmo;
- Kho elepromatous nodular ritema, pib nrog txog 400 mg rau ib hnub twg, thiab txo cov koob tshuaj rau 2 lub lis piam, kom txog rau thaum ncav cuag lub koob tshuaj saib xyuas, uas yog nruab nrab ntawm 50 txog 100 mg rau ib hnub.
- Debilitating syndrome, cuam tshuam nrog cov kab mob HIV: 100 txog 200 mg ib hnub ib zaug thaum yuav mus pw lossis 1 teev tom qab noj mov tas.
Thaum kho ib qho yuav tsum tsis muaj kev sib cuag thiab yog tias nws tshwm sim, ob txoj kev tiv thaiv yuav tsum siv tib lub sijhawm, xws li tshuaj muaj me nyuam tsis huv, txhaj tshuaj lossis cog hniav thiab looj lossis hnab looj qau. Ib qho ntxiv, nws yog ib qho tsim nyog yuav tsum pib tiv thaiv cev xeeb tub txog 1 hlis ua ntej pib kho thiab rau 4 lub lis piam tom qab kev txiav.
Thaum tus txiv neej uas muaj kev sib deev nrog poj niam thaum muaj hnub nyoog yug menyuam, lawv yuav tsum siv hnab looj txhua qhov chaw sib chwv.
Sab sij huam
Qhov tshwm sim feem ntau ntawm kev siv cov tshuaj no yog tias nws siv los ntawm tus poj niam cev xeeb tub, uas ua rau muaj kev cuam tshuam hauv cov menyuam. Ib qho ntxiv, nws tuaj yeem ua rau tingling, mob ntawm txhais tes, taw thiab neuropathy.
Lub plab zom mov ua tsis taus pa, tsaug zog, kiv taub hau, ntshav txhaws, mob leukopenia, mob leukemia, purpura, mob caj dab, mob nraub qaum, ntshav siab qis, ntshav khiav ceev, mob ntshav tawm tsam, lub plawv nres, ntxhov siab, poob siab, hlab ntsws, hnoos, mob plab, raws plab, lossis hauv tsev loj kuj tseem mob plab, mob daim tawv nqaij, ua kom tawv nqaij qhuav.
Cov Yuav Tsum Tau Ua
Kev siv cov tshuaj no muaj qhov cuam tshuam hauv kev xeeb tub vim nws ua rau muaj qhov tsis zoo ntawm tus menyuam, xws li tsis muaj ceg, caj npab, daim di ncauj lossis pob ntseg, ntxiv rau kev ua haujlwm tsis zoo hauv lub siab, lub raum, hnyuv thiab lub tsev menyuam.
Ntxiv rau, 40% ntawm cov menyuam tuag sai tom qab yug thiab nws tseem sib kis thaum pub niam mis, vim tias nws cov nyhuv tsis paub. Nws kuj tseem siv tsis tau thaum muaj kev fab tshuaj Thalidomide lossis ib qho ntawm cov khoom xyaw.