Soliqua 100/33 (insulin glargine / lixisenatide)

Zoo Siab

• Soliqua 100/33 yog dab tsi?
• Txij nkawm
• Soliqua 100/33 xaj
• Soliqua 100/33 tsuas noj
• Cov ntaub ntawv tshuaj thiab qhov ua tau zoo
• Tsuas tshuaj rau Soliqua 100/33
• Yog tias kuv plam koob tshuaj?
• Kuv puas yuav tau siv cov tshuaj no ntev?
• Soliqua 100/33 phiv
• Ntau cov kev mob tshwm sim
• Cov kev mob tshwm sim hnyav heev
• Soliqua 100/33 tus nqi
• Kev pab nyiaj thiab kev tuav pov hwm
• Yuav ua li cas noj Soliqua 100/33
• Yuav siv cov haujlwm li cas
• Sijhawm
• Noj Soliqua 100/33 nrog zaub mov
• Hloov mus rau Soliqua 100/33
• Soliqua 100/33 vs. Xultophy
• Kev Siv
• Cov ntaub ntawv tshuaj thiab kev tswj hwm
• Phiv thiab txaus ntshai
• Txij nkawm
• Cov nqi
• Soliqua 100/33 vs. lwm tshuaj
• Soliqua 100/33 vs. Lantus
• Soliqua 100/33 vs. Victoza
• Soliqua 100/33 vs. Toujeo
• Soliqua 100/33 vs. Adlyxin
• Soliqua 100/33 siv
• Soliqua 100/33 siv nrog lwm yam tshuaj
• Soliqua 100/33 thiab cawv
• Soliqua 100/33 kev sib txuam
• Soliqua 100/33 thiab lwm yam tshuaj noj
• Soliqua 100/33 thiab tshuaj ntsuab thiab tshuaj ntxiv
• Yuav ua li cas Soliqua 100/33 ua haujlwm
• Tshuaj insulin cuam tshuam li cas cov ntshav qab zib
• Dab tsi Soliqua 100/33 ua
• Yuav siv sijhawm ntev npaum li cas ua haujlwm?
• Soliqua 100/33 thiab cev xeeb tub
• Soliqua 100/33 thiab pub niam mis
• Cov lus nug nquag hais txog Soliqua 100/33
• Puas yog Soliqua 100/33 ua rau hnyav dua?
• Puas yog Soliqua 100/33 insulin?
• Puas yog Soliqua 100/33 ua haujlwm ntev?
• Puas yuav Soliqua 100/33 tuaj yeem siv los kho mob ntshav qab zib hom 1?
• Soliqua 100/33 lus ceeb toom
• Soliqua 100/33 overdose
• Tshuav cov tsos mob
• Dab tsi yog qhov ua txhaum cai dhau
• Soliqua 100/33 tas sij hawm thiab cia
• Cov ntaub ntawv tshaj lij rau Soliqua 100/33
• Cov Khoom Qhia
• Mechanism ntawm kev ua
• Pharmacokinetics thiab cov metabolism
• Cov Yuav Tsum Tau Ua
• Cia

Soliqua 100/33 yog dab tsi?

Soliqua 100/33 yog hom tshuaj uas nrov npe. Nws tau siv rau kev noj zaub mov zoo thiab tawm dag zog txhawm rau txhim kho cov ntshav qab zib cov ntshav hauv cov neeg laus uas muaj ntshav qab zib hom 2.

Soliqua 100/33 muaj ob yam tshuaj:

• insulin glargine, uas yog lub vev xaib ntev ntev
• lixisenatide, uas yog nyob rau chav kawm ntawm cov tshuaj hu ua glucagon-zoo li peptide 1 (GLP-1) receptor agonists

Soliqua 100/33 los ua ib tus cwj mem uas siv rau kev txhaj tshuaj nws tus kheej hauv qab daim tawv nqaij (subcutaneous). Txhua tus cwj mem muaj 3 mL ntawm cov tshuaj daws, nrog 100 units ntawm insulin glargine thiab 33 mcg ntawm lixisenatide ib mL ntawm kev daws. Cwjmem yog siv nrog cwj mem rab koob, uas tsis suav nrog cov npiv.

Txij nkawm

Soliqua 100/33 tau pom tias muaj txiaj ntsig zoo hauv kev kho mob ntshav qab zib hom 2. Hauv ib txoj kev tshawb fawb soj ntsuam, Soliqua 100/33 tau kuaj hauv cov neeg muaj ntshav qab zib hom 2 uas tau raug kho nrog cov insulins ntev ntev tsawg kawg rau lub hlis. Tom qab 30 lub lim tiam ntawm kev kho mob nrog Soliqua 100/33, cov neeg no tau txo qis hemoglobin A1c (HbA1c) los ntawm 1.1 feem pua. Lawv kuj tau txo kev yoo ntshav cov ntshav qab zib ntau ntau los ntawm 5.7 mg / dL.

Hauv lwm txoj kev tshawb nrhiav, Soliqua 100/33 tau siv nrog metformin rau 30 lub lis piam. Txoj kev tshawb no koom nrog cov neeg uas yav tas los tau siv tshuaj metformin ib leeg, lossis nrog metformin thiab lwm cov tshuaj tiv thaiv ntshav qab zib. Kev kho mob nrog Soliqua 100/33 thiab metformin txo HbA1c los ntawm 1.6 feem pua. Nws kuj tseem txo qis kev yoo ntshav cov ntshav qab zib ntau ntau los ntawm 59.1 mg / dL.

Soliqua 100/33 xaj

Soliqua 100/33 tsuas yog muaj raws li muaj koob npe tshuaj rau tshuaj noj. Tamsis no nws tsis muaj cov ntawv ua tsis raug.

Soliqua 100/33 muaj ob yam tshuaj: insulin glargine thiab lixisenatide. Cov tshuaj no tsis muaj nyob hauv cov ntawv sau qhia xwb.

Insulin glargine yog ib qho tshuaj insulin ntev ntev uas muaj nyob ntawm nws tus kheej li cov tshuaj uas nrov npe xws li Lantus, Toujeo, thiab Basaglar. Lixisenatide belongs rau chav kawm ntawm cov tshuaj hu ua glucagon-zoo li peptide 1 (GLP-1) receptor agonists. Nws muaj raws li cov tshuaj lag luam muaj npe Adlyxin.

Soliqua 100/33 tsuas noj

Feem ntau, koj tus kws kho mob yuav pib koj ntawm qhov tsawg kawg nkaus ntawm Soliqua 100/33 thiab kho nws thaum lub sijhawm dhau los kom ncav cuag qhov tshuaj uas haum rau koj. Qhov hloov txheej txheem no hu ua titration. Koj tus kws kho mob yuav muab tshuaj kom tsawg tshaj plaws uas qhia txog yam xav tau.

Cov ntaub ntawv hauv qab no piav qhia ntau npaum li cas cov tshuaj uas feem ntau siv los yog ua kom siv. Txawm li cas los xij, nco ntsoov siv qhov ntau npaum koj tus kws kho mob sau rau koj. Koj tus kws kho mob yuav txiav txim siab muab qhov zoo tshaj plaws kom haum koj cov kev xav tau.

Cov ntaub ntawv tshuaj thiab qhov ua tau zoo

Txhua lub pob ntawm Soliqua 100/33 muaj tsib lub pov tseg, npaj ua ntej Soliqua 100/33 hno cov cwj mem rau ib lub thawv. Cwj mem koob tsis suav nrog cov npiv. (Feem ntau, koj tuaj yeem yuav cov mem tes hauv lub tsev muag tshuaj. Koj yuav tsum tau siv tshuaj.)

Txhua tus cwj mem uas txhaj tshuaj muaj 3 mL ntawm kev daws tshuaj, nrog rau tag nrho 300 tawm ntawm insulin glargine thiab 100 mcg ntawm lixisenatide.

Soliqua 100/33 cwj mem kua yog txhua lub ntsiab lus tau siv ntau zaus. Tus naj npawb ntawm cov sij hawm tuaj yeem ua tau li 5 txog 20 zaug, nyob ntawm koj ntau npaum li cas. Txhua tus cwj mem tuaj yeem siv tau ntev txog 28 hnub tom qab siv thawj zaug. Tom qab lub sijhawm ntawd, koj yuav tsum pov tseg tus cwj mem, txawm tias nws tseem muaj qee cov tshuaj.

Tus cwj mem koob yuav tsum tsuas yog siv ib zaug ua ke.

Tsuas tshuaj rau Soliqua 100/33

Soliqua 100/33 feem ntau yog hais hauv kev txhaj tshuaj ib leeg ntawm 15 txog 60 units txhua qhov. Lo lus "chav nyob" yog daim ntawv ntsuas uas siv rau cov insulin glargine uas muaj nyob hauv Soliqua 100/33. Qhov ntau tshaj plaws hauv kev txhaj tshuaj ib zaug yog 60 units, uas yuav txhais tau tias 60 units ntawm insulin glargine thiab 20 mcg lixisenatide.

Pib muab tshuaj

Qhov pom zoo kom pib siv cov tshuaj Soliqua 100/33 yog nyob ntawm koj cov kev kho mob ntshav qab zib yav dhau los.

Lus khaws xav: Ua ntej pib Soliqua 100/33, koj yuav tsum tso tseg tag nrho lwm yam kev kho mob nrog lixisenatide lossis ua yeeb yam ntev ntev.

Txij nkawm ntau npaum

Tom qab pib siv Soliqua 100/33, koj tus kws kho mob yuav soj ntsuam koj cov ntshav qab zib kom tsawg thiab yuav hloov koj cov tshuaj kom haum rau koj. Cov neeg muag tshuaj pom zoo kom muab ib rab koob tshuaj los txo lossis tso tawm 2 mus rau 4 ntu txhua txhua lub limtiam raws li xav tau kom ua tau raws li cov ntshav qab zib cov hom phiaj.

Koob tshuaj kho

Koj thiab koj tus kws kho mob yuav ua haujlwm ua ke los tsim cov phiaj xwm kom ua tiav koj cov ntshav qab zib cov hom phiaj.

Hauv qab no yog ib qho piv txwv ntawm kev hloov kho koob tshuaj uas koj tus kws kho mob yuav pom zoo. Koj tus kws kho mob yuav txiav txim siab yog tias koj xav tau cov kev hloov kho no. Nco ntsoov tias koj noj cov tshuaj uas koj tus kws kho mob pom zoo. (Tsis txhob hloov koj cov tshuaj noj yam tsis muaj kev pom zoo los ntawm koj tus kws kho mob.)

Yog tias kuv plam koob tshuaj?

Yog tias koj plam koob tshuaj Soliqua 100/33, hla qhov koob tshuaj ntawd thiab txuas ntxiv nrog koj cov koob tshuaj tom ntej. Tsis txhob sim kom caum cuag los ntawm kev noj ib qho tshuaj ntxiv lossis nce ntxiv koob tshuaj ntxiv. Qhov no tuaj yeem ua rau muaj kev phom sij txaus ntshai.

Kuv puas yuav tau siv cov tshuaj no ntev?

Yog tias Soliqua 100/33 muaj txiaj ntsig thiab muaj kev nyab xeeb rau koj, koj yuav tau siv cov tshuaj no ntev. Soliqua 100/33 feem ntau yog siv ntev ntev los kho hom 2 ntshav qab zib.

Soliqua 100/33 phiv

Soliqua 100/33 tuaj yeem ua rau mob hnyav lossis mob hnyav. Cov npe hauv qab no muaj qee qhov kev mob tshwm sim uas yuav tshwm sim thaum noj Soliqua 100/33. Daim ntawv no tsis suav nrog tag nrho cov kev mob tshwm sim.

Yog xav paub ntxiv txog cov kev phiv los sis Soliqua 100/33, lossis cov lus qhia yuav ua li cas nrog cov kev mob tshwm sim, nrog koj tus kws kho mob lossis kws muag tshuaj tham.

Ntau cov kev mob tshwm sim

Cov kev mob tshwm sim ntau dua los ntawm Soliqua 100/33 tuaj yeem suav nrog:

• xeev siab
• cov mob ua pa xws li khaub thuas lossis mob aws
• zawv plab
• mob taub hau
• hypoglycemia (cov ntshav qab zib tsawg)

Feem ntau ntawm cov kev mob tshwm sim no yuav ploj mus li ntawm ob peb hnub lossis ob peb lub lis piam. Yog tias lawv mob hnyav dua lossis tsis ploj mus, nrog koj tus kws kho mob lossis kws muag tshuaj tham.

Cov kev mob tshwm sim hnyav heev

Cov kev phiv loj los ntawm Soliqua 100/33 tsis yog muaj tshwm sim ntau, tab sis lawv tuaj yeem tshwm sim. Hu rau koj tus kws kho mob tam sim ntawd yog tias koj muaj kev phiv loj heev. Hu 911 yog koj tus mob hnov ​​lub neej tsis zoo lossis yog koj xav tias koj muaj mob xwm txheej kub ntxhov ceev.

Cov kev mob tshwm sim hnyav heev thiab lawv cov tsos mob tuaj yeem suav nrog cov hauv qab no:

• Kev fab loj heev rau fab. Cov tsos mob tuaj yeem suav nrog:
• ua pob
• yaug
• o tuaj
• khaus tawv
• teeb meem ua pa
• ntshav siab
• Pancreatitis (mob rau hauv qab thiav). Cov tsos mob tuaj yeem suav nrog:
• mob lossis mob hauv koj lub plab
• rov qab mob
• xeev siab
• ntuav
• ua npaws
• poob phaus
• Raum puas. Cov tsos mob tuaj yeem suav nrog:
• txo qis tso zis
• o hauv koj txhais ceg, pob taws, lossis ko taw
• tsis meej pem
• nkees
• xeev siab
• mob hauv siab lossis siab
• lub plawv dhia tsis xwm yeem
• qaug dab peg
• Hypokalemia (muaj poov tshuaj tsawg). Cov tsos mob tuaj yeem suav nrog:
• tsis muaj zog
• nkees
• cem quav
• mob leeg
• lub plawv dhia tsis xwm yeem

Qhov hnyav los sis ceeb thawj

Hauv kev sim tshuaj, Soliqua 100/33 nrhiav tsis tau kom hloov qhov hnyav. Txawm li cas los xij, hauv ib qhov kev tshawb fawb soj ntsuam, cov neeg uas siv tshuaj Soliqua 100/33 rau 30 lub lis piam poob txog 1.5 phaus.

Ntxiv rau, cov tshuaj ib leeg muaj nyob hauv Soliqua 100/33 tau txuas nrog kev hloov phaus. Soliqua 100/33 muaj cov tshuaj insulin glargine, cov tshuaj insulin ntev ntev. Cov tshuaj uas muaj cov tshuaj insulin tuaj yeem ua rau nce phaus ntxiv.

Soliqua 100/33 kuj tseem muaj lixisenatide, ib qho glucagon zoo li peptide 1 (GLP-1) receptor agonist. Hauv ntau qhov kev tshawb fawb soj ntsuam, cov tshuaj hauv GLP-1 cov tshuaj qhia tau pom kev poob phaus yog qhov tshwm sim.

Yog tias koj txhawj xeeb txog kev hloov phaus thaum siv Soliqua 100/33, nrog koj tus kws kho mob tham.

Kev ntshav siab

Cov tshuaj Insulin, ib qho ntawm cov tshuaj hauv Soliqua 100/33, yog siv los pab txo cov ntshav qab zib kom qis. Txawm li cas los xij, cov ntshav qab zib cov ntshav yuav tuaj yeem txo qis dhau, uas ua rau nws muaj ntshav qab zib tsawg. Kev mob ntshav siab yog qhov tshwm sim feem ntau tshwm sim los ntawm cov tshuaj insulin, suav nrog Soliqua 100/33.

Hauv cov kev tshawb fawb soj ntsuam, hypoglycemia tshwm sim nyob rau hauv 8.1 rau 17.8 feem pua ​​ntawm cov neeg siv Soliqua 100/33. Thiab mob ntshav nce siab ntau tshwm sim nyob hauv kwv yees li 1 feem pua ​​ntawm tib neeg noj tshuaj.

Ntau yam tuaj yeem ua rau koj muaj kev pheej hmoo ntawm cov ntshav qab zib. Cov no suav nrog kev noj tshuaj ntau dua ntawm koj cov ntshav qab zib thiab siv ntau dua ib hom tshuaj mob ntshav qab zib. Lwm yam uas tuaj yeem cuam tshuam koj txoj kev pheej hmoo suav nrog koj kev noj haus thiab kev tawm dag zog, thiab seb koj puas noj lwm yam tshuaj.

Cov tsos mob ntawm tus mob ntshav qab zib tsawg tuaj yeem tshwm sim sai thiab tuaj yeem suav nrog kev txaj muag, qaug zog, tsaug zog thiab tsis meej pem. Mob ntshav qab zib heev tuaj yeem ua rau muaj kev phiv loj heev xws li qaug dab peg lossis tuag taus. Tham nrog koj tus kws kho mob hais txog qhov koj yuav tsum xyuas koj cov ntshav qab zib kom tsis txhob mob ntshav qab zib thaum noj Soliqua 100/33.

Kev ntxhov siab lossis daim tawv tuab

Koj noj tshuaj Soliqua 100/33 los ntawm kev txhaj tshuaj subcutaneous, uas txhais tau tias koj txhaj rau hauv qab koj daim tawv nqaij. Qhov txhaj tshuaj subcutaneous tuaj yeem ua rau lipodystrophy (kev nyuaj siab lossis ua rau daim tawv nqaij tuab) ncig thaj chaw txhaj tshuaj.

Txo qhov kev pheej hmoo ntawm lipodystrophy, hloov pauv cov chaw uas koj txhaj tshuaj. Piv txwv, muaj ib hnub koj tuaj yeem hno cov tshuaj rau hauv koj lub plab, thiab lwm hnub koj tuaj yeem siv koj sab ncej puab sab nraud.

Yog tias koj muaj kev txhawj xeeb txog daim tawv nqaij tshwm sim los ntawm kev txhaj tshuaj Soliqua 100/33, tham nrog koj tus kws kho mob.

Raum puas

Lub raum puas tsuaj tsis tau pom hauv kev tshawb nrhiav soj ntsuam ntawm Soliqua 100/33. Txawm li cas los xij, muaj ntawv tshaj tawm txog kev mob raum hauv cov neeg kho nrog glucagon-zoo li peptide 1 (GLP-1) tshuaj. Lixisenatide, uas yog ib qho tshuaj nyob hauv Soliqua 100/33, yog GLP-1 tshuaj.

Cov tsos mob ntawm lub raum puas tsuaj tuaj yeem suav nrog:

• o ntawm cov ceg, pob taws, lossis taw
• nkees
• xeev siab
• ntuav

Kab mob hauv lub raum feem ntau tshwm sim rau cov neeg uas lub cev qhuav dej vim qee yam tshwm sim ntawm Soliqua 100/33, xws li xeev ntuav, ntuav, thiab zawv plab.

Yog tias koj muaj cov tsos mob no thaum noj Soliqua 100/33, lossis muaj kev txhawj xeeb txog koj lub raum noj qab haus huv, tham nrog koj tus kws kho mob.

Soliqua 100/33 tus nqi

Ib yam li txhua yam tshuaj, tus nqi ntawm Soliqua 100/33 tuaj yeem sib txawv.

Koj tus nqi tiag tiag yuav nce nyob ntawm koj qhov kev tuav pov hwm.

Kev pab nyiaj thiab kev tuav pov hwm

Yog tias koj xav tau kev txhawb nqa nyiaj txiag los them rau Soliqua 100/33, kev pabcuam yeej muaj. Sanofi Aventis, lub chaw tsim khoom ntawm Soliqua 100/33, muaj Soliqua 100/33 Txuag Nyiaj. Yog xav paub ntaub ntawv ntau ntxiv, txuas mus xyuas lub vev xaib program.

Yuav ua li cas noj Soliqua 100/33

Hauv qab no yog qee cov lus qhia yooj yim yuav ua li cas txhaj tshuaj koj tus kheej uas siv lub Soliqua 100/33 cwj mem. Nco ntsoov nco ntsoov noj cov tshuaj Soliqua 100/33 raws li koj tus kws kho mob lossis tus kws saib xyuas kev noj qab haus huv cov lus qhia.

Yuav siv cov haujlwm li cas

Kauj Ruam 1. Npaj thiab xyuas koj tus cwj mem.

Yog tias qhov no yog koj thawj zaug siv, coj tus cwj mem tawm hauv lub tub yees thiab cia tus cwj mem kom ncav cuag kub chav.

• Sau cov dej cawv cawv, ib rab koob tshiab, thiab koj lub khob ntim pov tseg.
• Ntxuav koj ob txhais tes.
• Tshem tus cwj mem cwj mem thiab ua kom cov tshuaj kom meej thiab tsis muaj xim. (Tsis txhob siv yog tias txoj kev daws teeb meem tsis meej thiab tsis muaj kob. Cov npuas huab cua zoo.)
• Ntxuav cov roj hmab foob nrog tus cawv cawv cawv.

Kauj Ruam 2. Txuas tus cwj mem tshiab.

Rau txhua qhov kev txhaj tshuaj, ib txwm siv tus cwj mem tshiab. Nco ntsoov tias tus cwj mem cwj mem tuaj yeem siv nrog Soliqua 100/33. Yog tias koj tsis paub yuav siv cov koob twg, nug koj tus kws kho mob lossis kws muag tshuaj.

• Tshem tus cwj mem tawm los ntawm nws lub pob tiv thaiv.
• Txheem tus cwj mem kom ncaj, twist nws rau hauv cwj mem.
• Tshem lub hau npab sab nraud thiab teem nws sab. (Khaws nws siv rau tom qab txhaj tshuaj.)
• Tshem lub hau taub ntawm sab hauv thiab muab pov tseg rau hauv thoob khib nyiab.

Kauj Ruam 3. Ua qhov ntsuas kev nyab xeeb.

Yuav tsum ntsuas kev nyab xeeb tas li ua ntej txhua yam kev txhaj tshuaj kom paub tseeb tias tus cwj mem thiab rab koob ua haujlwm zoo.

• Kho qhov ntsuas nyiaj koob tshuaj kom nws nyeem 2 ib ntu.
• Nias lub pob txhaj tshuaj kiag li hauv thiab khij ib qho tshuaj kho me ntsis kom tawm los ntawm rab koob rab koob. Yog tias qhov no tshwm sim, ua mus rau kauj ruam 4.
• Yog tias tsis muaj tshuaj tawm, rov ua qhov ntsuas kev nyab xeeb txog 3 zaug.
• Yog tias tsis muaj tshuaj tawm tom qab peb qhov kev sim, hloov lub koob thiab rov ua qhov ntsuas kev nyab xeeb.
• Yog tias tsis muaj tshuaj tawm tom qab hloov rab koob, tsis txhob siv tus cwj mem vim tias nws yuav raug puas ntsoog. Siv tus cwj mem tshiab.

Kauj Ruam 4. Xaiv koj cov tshuaj.

• Tig lub txee tshuaj kom txog thaum koj tau txais koj cov tshuaj lawm.

Kauj Ruam 5. Nto koob tshuaj.

Muaj peb thaj chaw ntawm koj lub cev koj tuaj yeem siv rau qhov chaw txhaj tshuaj: koj lub plab (tshwj tsis pub dhau 2 ntiv ntawm koj lub plab hauv plab), sab nraub qaum ntawm koj sab caj npab (thaj chaw rog), thiab koj sab ncej puab sab nraud.

• Xaiv qhov chaw txhaj tshuaj thiab so cov tawv nqaij ntawm qhov chaw nrog dej cawv cawv.
• Ntawm qhov chaw txhaj tshuaj, ntxig rab koob rau hauv koj cov tawv nqaij ntawm 90-degree.
• Nias lub pob txhaj tshuaj kom qis thiab tuav kom txog thaum koj pom “0” rau ntawm lub qhov rai txhaj tshuaj.
• Tom qab lub txee tshuaj tig mus rau "0," suav rau 10 ua ntej tso lub pob txhaj tshuaj thiab hle rab koob. Qhov kev ncua no pab xyuas kom koj tau txais cov tshuaj puv.
• Tso lub pob txhaj tshuaj thiab tshem tawm rab koob ntawm koj cov tawv nqaij.

Kauj Ruam 6. Pov tseg rab koob thiab khaws cwj mem.

• Tso rab koob sab nrauv tso rau tom qab rab koob.
• Tshem tawm rab koob tawm ntawm lub qhov txhaj txhaj tshuaj thiab muab pov tseg tam sim ntawd rab koob rau hauv cov thawv ntim khoom ntse. (Muab nws pov tseg tam sim ntawd kom tsis txhob ua rau nws nrog ib rab koob tshiab.)
• Muab tus cwj mem rov los rau ntawm tus cwj mem.
• Khaws tus cwj mem nyob rau hauv chav tsev kub tom qab siv thawj zaug.

Sijhawm

Koj yuav tsum noj Soliqua 100/33 hauv teev ua ntej koj noj mov thawj hnub.

Noj Soliqua 100/33 nrog zaub mov

Soliqua 100/33 tsis txhob noj nrog zaub mov. Nws yuav tsum tau ua nyob rau hauv ib teev ua ntej koj noj mov thawj hnub.

Hloov mus rau Soliqua 100/33

Lwm yam tshuaj muaj peev xwm kho tus mob ntshav qab zib hom 2 tau. Qee tus kuj yuav zoo dua rau koj dua li lwm tus. Yog tias koj xav nrhiav lwm txoj hauv kev rau Soliqua 100/33, tham nrog koj tus kws kho mob kom paub ntxiv txog lwm yam tshuaj uas yuav ua haujlwm zoo rau koj.

Soliqua 100/33 muaj ob yam tshuaj: insulin ntev ntev hu ua insulin glargine, thiab glucagon zoo li peptide 1 (GLP-1) receptor agonist hu ua lixisenatide.

Piv txwv ntawm cov tshuaj uas yuav siv los ua lwm txoj kev Soliqua 100/33 suav nrog:

• Cov insulins ntev-ntev, xws li:
• tshuaj insulin glargine (Lantus, Toujeo)
• Tshuaj insulin (Levemir)
• GLP-1 receptor agonists, xws li:
• exenatide (Bydureon, Byetta)
• liraglutide (Victoza, Saxenda)
• lixisenatide (Adlyxin)
• semaglutide (Ozempic)
• dipeptidyl peptidase-4 (DPP-4) inhibitors, xws li:
• alogliptin (Nesina)
• linagliptin (Tradjenta)
• saxagliptin (Onglyza)
• sitagliptin (Januvia)
• meglitinides, xws li:
• kho siab (Prandin)
• pawg (Starlix)
• metformin (Glucophage, Glumetza, Riomet)
• sodium-glucose cotransporter 2 (SGLT2) cov tshuaj tiv thaiv kab mob, xws li:
• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• sulfonylureas, xws li:
• tshuaj pleev qhov muag (Amaryl)
• glipizide (Glucotrol)
• glyburide (DiaBeta, Glynase)
• thiazolidinediones, xws li:
• pioglitazone (Actos)
• rosiglitazone (Avandia)

Soliqua 100/33 vs. Xultophy

Tej zaum koj yuav xav paub seb Soliqua 100/33 piv rau lwm cov tshuaj uas tau sau tseg rau kev siv zoo sib xws.Ntawm no peb saib yuav ua li cas Soliqua 100/33 thiab Xultophy zoo ib yam thiab txawv.

Kev Siv

Soliqua 100/33 thiab Xultophy yog ob leeg FDA-pom zoo txhawm rau txhim kho cov ntshav qab zib cov ntshav hauv cov neeg mob ntshav qab zib hom 2. Lawv tau ob qho tshuaj rau siv nrog hloov pauv kev noj haus thiab qoj ib ce.

Soliqua 100/33 thiab Xultophy ob leeg muaj ob yam tshuaj, thiab cov tshuaj no sawv daws koom nrog kev noj tshuaj ua ke. Qhov no txhais tau tias lawv ua haujlwm ib yam nkaus hauv lub cev.

Soliqua 100/33 muaj:

• insulin glargine (insulin ntev ntev)
• lixisenatide (zoo li peptide glucagon 1 [GLP-1] receptor agonist)

Xultophy muaj:

• insulin degludec (insulin ntev ntev)
• liraglutide (GLP-1 receptor agonist)

Cov ntaub ntawv tshuaj thiab kev tswj hwm

Soliqua 100/33 thiab Xultophy ob qho tib si tuaj ua kua tov rau hauv cov xaum pov tseg. Lawv muab ob qho tib si txhaj rau tus kheej hauv qab daim tawv nqaij (raug mob) ib hnub ib zaug.

Phiv thiab txaus ntshai

Soliqua 100/33 thiab Xultophy muaj cov teebmeem zoo sib xws hauv lub cev thiab yog li ua rau muaj kev phiv zoo heev.

Ntau cov kev mob tshwm sim

Daim ntawv no muaj cov piv txwv ntawm cov kev mob tshwm sim uas feem ntau yuav tshwm sim nrog ob qho tshuaj (thaum noj ib qho zuj zus).

• Yuav tshwm sim nrog ob Soliqua 100/33 thiab Xultophy:
• cov mob ua pa xws li khaub thuas lossis mob aws
• xeev siab
• zawv plab
• mob taub hau
• hypoglycemia (cov ntshav qab zib tsawg)

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim hnyav uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Xultophy, lossis nrog ob qho tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
• ob peb yam kev phiv loj heev
• Yuav tshwm sim nrog Xultophy:
• cov qog nqaij hlav cancer *
• kab mob gallbladder
• Yuav tshwm sim nrog ob Soliqua 100/33 thiab Xultophy:
• kev fab tshuaj hnyav heev
• Mob ntshav qab zib heev (muaj ntshav qab zib tsawg heev)
• pancreatitis (mob rau hauv qab)
• raum puas tsuaj
• hypokalemia (qib qis poov tshuaj)

* Xultophy muaj lub thawv ceeb toom los ntawm FDA rau kev mob qog noj ntshav. Lub thawv ceeb toom yog qhov kev ceeb toom zoo tshaj plaws ntawm FDA tau hais. Nws ceeb toom cov kws kho mob thiab cov neeg mob txog tshuaj phiv uas tuaj yeem tsim kev puas tsuaj.

Txij nkawm

Soliqua 100/33 thiab Xultophy tsis tau muab piv rau hauv kev tshawb nrhiav hauv chav kho mob, tab sis ob qho tib si pom tau tias muaj txiaj ntsig zoo los kho ntshav qab zib hom 2.

Hauv cov kev tshawb fawb cais, Soliqua 100/33 thiab Xultophy ob leeg ua haujlwm zoo rau txo qis HbA1c thiab yoo ntshav cov ntshav qab zib ntau ntau.

• Hauv qhov kev tshawb fawb soj ntsuam, Soliqua 100/33 txo cov hemoglobin A1c (HbA1c) los ntawm 1.1 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 5.7 mg / dL tom qab 30 lub lim tiam ntawm kev kho mob.
• Hauv cov kev tshawb fawb soj ntsuam, Xultophy txo HbA1c los ntawm 1.31 mus rau 1.94 feem pua ​​thiab yoo cov ntshav qab zib cov ntshav ntau los ntawm 49.9 mg / dL rau 63.5 mg / dL tom qab 26 lub lis piam ntawm kev kho mob. Cov neeg siv Xultophy tseem tau nce txog 4,4 phaus ntau dua li 26 lub lim tiam ntawm kev kho mob.

Lus khaws xav: Nws yog ib qho tseem ceeb uas yuav tau nco rau hauv siab tias cov tshuaj no yuav txo qis koj li HbA1c lossis ntshav qab zib cov ntshav yuav nyob ntawm ntau yam, nrog rau:

• koj cov piam thaj hauv ntshav thaum koj pib siv tshuaj
• koj kev noj kev haus thiab kev tawm dag zog
• lwm cov tshuaj ntshav qab zib uas koj noj
• koj yuav tsum ua raws li kev kho koj li cas

Cov nqi

Soliqua 100/33 thiab Xultophy yog ob hom tshuaj muaj npe. Tam sim no tsis muaj cov ntawv sau rau ib qho ntawm cov tshuaj. Cov tshuaj muaj npe lag luam feem ntau raug nqi ntau dua li cov generics.

Raws li kev kwv yees los ntawm GoodRx.com, Xultophy yuav kim dua Soliqua 100/33. Tus nqi tiag uas koj yuav them rau ib qho tshuaj twg yog nyob ntawm koj qhov koob tshuaj, koj qhov kev pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj siv.

Soliqua 100/33 vs. lwm tshuaj

Muaj lwm cov tshuaj ntxiv rau Soliqua 100/33 thiab Xultophy (saum toj) uas tuaj yeem siv los kho hom ntshav qab zib 2. Hauv qab no yog cov kev sib piv ntawm Soliqua 100/33 thiab ob peb lwm yam tshuaj.

Soliqua 100/33 vs. Lantus

Soliqua 100/33 muaj ob yam tshuaj:

• insulin glargine, uas yog lub vev xaib ntev ntev
• lixisenatide, uas yog nyob rau chav kawm ntawm cov tshuaj hu ua glucagon-zoo li peptide 1 (GLP-1) receptor agonists

Insulin glargine yog cov tshuaj uas muaj nyob hauv Lantus. Vim tias Soliqua 100/33 thiab Lantus sib koom ua ke, lawv ua haujlwm zoo sib xws hauv lub cev.

Kev Siv

Soliqua 100/33 yog FDA pom zoo rau kev siv nrog kev hloov kev noj haus thiab kev tawm dag zog txhawm rau txhim kho cov ntshav qab zib cov ntshav hauv cov neeg muaj ntshav qab zib hom 2.

Lantus yog FDA pom zoo los txhim kho cov ntshav qab zib hauv cov neeg laus thiab cov menyuam yaus uas muaj ntshav qab zib hom 1, thiab cov laus uas muaj ntshav qab zib hom 2.

Cov ntaub ntawv tshuaj thiab kev tswj hwm

Soliqua 100/33 los ua kua tov rau hauv cov xaum pov tseg. Lantus los ua kua roj hauv ntau-ntau vial lossis hauv qhov hno uas muab pov tseg. Ob qho tshuaj no yog txhaj rau tus kheej hauv qab daim tawv nqaij (subcutaneous) ib hnub ib zaug.

Phiv thiab txaus ntshai

Soliqua 100/33 thiab Lantus ob leeg puav leej muaj tib yam nkaus cov insulin ntev ntev, insulin glargine. Yog li, ob hom tshuaj ua rau muaj kev phiv zoo heev. Hauv qab no yog cov piv txwv ntawm cov kev mob tshwm sim no.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm ntau cov kev mob tshwm sim uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Lantus, lossis nrog ob hom tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • xeev siab
  • cov mob ua pa xws li khaub thuas lossis mob aws
  • mob taub hau
  • zawv plab
• Muaj peev xwm tshwm sim nrog Lantus:
  • hnyav
  • lipodystrophy (indentation los yog thickening ntawm daim tawv nqaij ntawm qhov chaw txhaj tshuaj)
  • qhov chaw txhaj tshuaj tiv thaiv
• Muaj peev xwm tshwm sim nrog ob Soliqua 100/33 thiab Lantus:
  • hypoglycemia (cov ntshav qab zib tsawg)

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim loj uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Lantus, lossis nrog ob qho tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • pancreatitis (mob rau hauv qab)
  • raum puas tsuaj
• Muaj peev xwm tshwm sim nrog Lantus:
  • ob peb yam kev phiv loj heev
• Muaj peev xwm tshwm sim nrog ob Soliqua 100/33 thiab Lantus:
  • kev fab tshuaj hnyav heev
  • Mob ntshav qab zib heev (muaj ntshav qab zib tsawg heev)
  • cov poov tshuaj noj kom qis (hypokalemia)

Txij nkawm

Qhov ua tau zoo ntawm Soliqua 100/33 thiab Lantus tau ncaj qha piv rau ob txoj kev tshawb nrhiav. Hauv thawj txoj kev tshawb nrhiav, ob qho tshuaj yeeb tshuaj tau siv rau ib leeg. Hauv ob, lawv tau siv ua ke nrog metformin (ib qho tshuaj mob ntshav qab zib hauv qhov ncauj).

Siv nyob ib leeg

Thawj qhov kev tshawb fawb tau tsom rau cov neeg laus uas muaj ntshav qab zib hom 2 uas yav dhau los kho cov insulins ntev ntev. Nws pom tias Soliqua 100/33 tuaj yeem ua haujlwm me ntsis zoo dua li Lantus rau txo qis hemoglobin A1c (HbA1c), tab sis tsis zoo rau txo qis cov ntshav qab zib kom ntau.

Tom qab 30 lub hlis ntawm kev kho mob, Soliqua 100/33 txo HbA1c los ntawm 1.1 feem pua, thiab yoo cov ntshav qab zib ntau ntau los ntawm 5.7 mg / dL. Lub sijhawm tib lub sijhawm, Lantus txo qis HbA1c los ntawm 0.6 feem pua, thiab yoo cov ntshav qab zib ntau ntau los ntawm 7.0 mg / dL.

Siv nrog metformin

Qhov kev tshawb nrhiav thib ob tau soj ntsuam Soliqua 100/33 nrog metformin tiv thaiv Lantus nrog metformin rau cov neeg laus uas muaj ntshav qab zib hom 2. Cov neeg no yav tas los tau siv tshuaj metformin ib leeg, lossis nrog metformin thiab lwm yam tshuaj mob ntshav qab zib hauv qhov ncauj.

Tshaj 30 lub lis piam, Soliqua 100/33 nrog metformin ua tau zoo dua li Lantus nrog metformin. Soliqua 100/33 nrog metformin txo HbA1c los ntawm 1.6 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 59.1 mg / dL. Ntawm qhov ua tsis tau muaj lantus thiab metformin, txo tus mob HbA1c los ntawm 1.3 feem pua ​​thiab txo cov ntshav qab zib cov ntshav tsawg dua 55.8 mg / dL.

Nco tseg: Nws tseem ceeb heev uas yuav tsum nco ntsoov tias zoo li cas ntawm cov tshuaj no yuav txo qis koj li HbA1c lossis ntshav qab zib cov ntshav yuav nyob ntawm ntau yam, nrog rau:

• koj cov piam thaj hauv ntshav thaum koj pib siv tshuaj
• koj kev noj kev haus thiab kev tawm dag zog
• lwm cov tshuaj ntshav qab zib uas koj noj
• koj yuav tsum ua raws li kev kho koj li cas

Cov nqi

Soliqua 100/33 thiab Lantus yog ob hom tshuaj muaj npe. Tam sim no tsis muaj cov ntawv sau rau ib qho ntawm cov tshuaj. Cov tshuaj muaj npe lag luam feem ntau raug nqi ntau dua li cov generics.

Raws li kev kwv yees los ntawm GoodRx.com, Lantus feem ntau raug nqi qis dua li Soliqua 100/33. Tus nqi tiag uas koj yuav them rau ib qho tshuaj twg yog nyob ntawm koj qhov koob tshuaj, koj txoj kev npaj fajseeb khomob, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj siv.

Soliqua 100/33 vs. Victoza

Soliqua 100/33 muaj ob yam tshuaj:

• insulin glargine, uas yog lub vev xaib ntev ntev
• lixisenatide, uas yog nyob rau chav kawm ntawm cov tshuaj hu ua glucagon-zoo li peptide 1 (GLP-1) receptor agonists

Victoza muaj cov tshuaj liraglutide, uas tseem yog GLP-1 receptor agonist. Vim tias Soliqua 100/33 thiab Victoza sib koom ua ke hauv tib chav tshuaj, lawv ua haujlwm zoo sib xws hauv lub cev.

Kev Siv

Soliqua 100/33 yog FDA pom zoo los txhim kho cov ntshav qab zib hauv cov neeg laus uas muaj ntshav qab zib hom 2. Nws yog qhov yuav tsum tau siv nrog kev hloov khoom noj thiab qoj ib ce.

Victoza tseem raug pom zoo los txhim kho cov ntshav qab zib hauv cov neeg laus uas muaj ntshav qab zib hom 2 txuam nrog kev txhim kho kev noj haus thiab kev tawm dag zog. Ntxiv rau, nws tau pom zoo los txo cov kev pheej hmoo ntawm teeb meem mob plawv loj xws li mob plawv thiab mob hlab ntsha tawg rau cov neeg muaj ntshav qab zib hom 2 thiab kab mob plawv.

Cov ntaub ntawv tshuaj thiab kev tswj hwm

Ob qho tib si Soliqua 100/33 thiab Victoza tau los ua kua tov rau hauv cov xaum pov tseg. Ob qho tshuaj no yog txhaj rau tus kheej hauv qab daim tawv nqaij (subcutaneous) ib hnub ib zaug.

Phiv thiab txaus ntshai

Vim tias Soliqua 100/33 thiab Victoza ob leeg puav leej muaj cov tshuaj nyob hauv GLP-1 tshuaj, ob qho tshuaj no tuaj yeem tsim kev phiv zoo heev. Hauv qab no yog cov piv txwv ntawm cov kev mob tshwm sim no.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm ntau cov kev mob tshwm sim uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Victoza, lossis nrog ob qho tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • hypoglycemia (cov ntshav qab zib tsawg)
  • cov mob ua pa xws li khaub thuas lossis mob aws
  • mob taub hau
• Yuav tshwm sim nrog Victoza:
  • tsis qab los
  • ntuav
  • cem quav
  • mob plab dhau
• Yuav tshwm sim nrog ob qho tib si Soliqua 100/33 thiab Victoza:
  • xeev siab
  • zawv plab

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim loj uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Victoza, lossis nrog ob yam tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • hypokalemia (qib qis poov tshuaj)
• Yuav tshwm sim nrog Victoza:
  • cov qog nqaij hlav cancer *
  • kab mob gallbladder
• Muaj peev xwm tshwm sim nrog ob qho tib si Soliqua 100/33 thiab Victoza:
  • kev fab tshuaj hnyav heev
  • Mob ntshav qab zib heev (muaj ntshav qab zib tsawg heev)
  • pancreatitis (mob rau hauv qab)
  • raum puas tsuaj

* Victoza muaj lub thawv ceeb toom los ntawm FDA rau mob qog noj ntshav. Lub thawv ceeb toom yog qhov kev ceeb toom zoo tshaj plaws ntawm FDA tau hais. Nws ceeb toom cov kws kho mob thiab cov neeg mob txog tshuaj phiv uas tuaj yeem tsim kev puas tsuaj.

Txij nkawm

Soliqua 100/33 thiab Victoza tsis tau piv rau hauv kev tshawb nrhiav hauv chav kho mob, tab sis ob qho tib si pom tau tias muaj txiaj ntsig zoo los kho ntshav qab zib hom 2.

Hauv kev tshawb fawb cais, ob qho Soliqua 100/33 thiab Victoza txo qis HbA1c thiab yoo cov ntshav qab zib cov ntshav ntau ntau hauv cov neeg muaj ntshav qab zib hom 2.

• Hauv kev soj ntsuam, tom qab 30 lub lim tiam ntawm kev kho mob, Soliqua 100/33 txo qis hemoglobin A1c (HbA1c) los ntawm 1.1 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 5.7 mg / dL.
• Hauv lwm qhov kev tshawb fawb hauv kev kho mob, dhau 52 lub lim tiam ntawm kev kho mob, Victoza txo HbA1c li ntawm 0.8 rau 1.1 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 15 txog 26 mg / dL.

Ib qho kev tshawb nrhiav cais qhia tau hais tias Victoza txo qis kev pheej hmoo ntawm cov teeb meem loj hauv lub plawv xws li mob plawv thiab mob hlab ntsha tawg mus 13 feem pua. Qhov tshwm sim no tsis tau kawm txog kev tshawb fawb ntawm Soliqua 100/33.

Lus khaws xav: Nws yog ib qho tseem ceeb uas yuav tau nco rau hauv siab tias cov tshuaj no yuav txo qis koj li HbA1c lossis ntshav qab zib cov ntshav yuav nyob ntawm ntau yam, nrog rau:

• koj cov piam thaj hauv ntshav thaum koj pib siv tshuaj
• koj kev noj kev haus thiab kev tawm dag zog
• lwm cov tshuaj ntshav qab zib uas koj noj
• koj yuav tsum ua raws li kev kho koj li cas

Cov nqi

Soliqua 100/33 thiab Victoza yog ob hom tshuaj muaj npe. Tam sim no tsis muaj cov ntawv sau rau ib qho ntawm cov tshuaj. Cov tshuaj muaj npe lag luam feem ntau raug nqi ntau dua li cov generics.

Raws li kev kwv yees los ntawm GoodRx.com, Victoza feem ntau raug nqi ntau dua li Soliqua 100/33. Tus nqi tiag uas koj yuav them rau ib qho tshuaj twg yog nyob ntawm koj ntau npaum cas, koj hom kev fajseeb khomob, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj siv.

Soliqua 100/33 vs. Toujeo

Soliqua 100/33 muaj ob yam tshuaj:

• insulin glargine, uas yog lub vev xaib ntev ntev
• lixisenatide, uas yog nyob rau chav kawm ntawm cov tshuaj hu ua glucagon-zoo li peptide 1 (GLP-1) receptor agonists

Insulin glargine yog cov tshuaj uas muaj nyob hauv Toujeo. Vim tias Soliqua 100/33 thiab Toujeo koom nrog cov khoom xyaw ua haujlwm, lawv ua haujlwm zoo sib xws hauv lub cev.

Kev Siv

Soliqua 100/33 yog FDA pom zoo los txhim kho cov ntshav qab zib hauv cov neeg laus uas muaj ntshav qab zib hom 2. Nws raug pom zoo rau kev siv nrog kev hloov khoom noj thiab qoj ib ce.

Toujeo yog FDA-pom zoo los txhim kho cov ntshav qab zib hauv cov neeg mob ntshav qab zib hom 2, thiab cov neeg laus thiab cov menyuam muaj ntshav qab zib hom 1.

Cov ntaub ntawv tshuaj thiab kev tswj hwm

Soliqua 100/33 thiab Toujeo ob qho tib si tuaj ua kua tov rau hauv cov xaum pov tseg. Ob qho tshuaj no yog txhaj rau tus kheej hauv qab daim tawv nqaij (subcutaneous) ib hnub ib zaug.

Soliqua 100/33 los hauv ib qhov nyiaj. Txhua tus cwj mem muaj 3 mL ntawm cov tshuaj daws, nrog 300 units ntawm insulin glargine thiab 100 mcg ntawm lixisenatide. Qhov ntau tshaj plaws hauv kev txhaj tshuaj ib zaug yog 60 units, uas yuav txhais tau tias 60 units ntawm insulin glargine thiab 20 mcg lixisenatide.

Toujeo los ntawm ob qhov sib txawv:

• Toujeo SoloStar muaj 450 units ntawm insulin glargine hauv 1.5 mL ntawm kev daws, nrog qhov siab tshaj plaws ntawm 80 units hauv kev txhaj ib.
• Toujeo Max SoloStar muaj 900 units ntawm insulin glargine hauv 3 mL ntawm kev daws teeb meem, qhov siab tshaj plaws ntawm 160 units ntawm kev txhaj tshuaj.

Phiv thiab txaus ntshai

Soliqua 100/33 thiab Toujeo ob leeg sib koom ua ke tib yam nkaus insulin, insulin glargine. Yog li, ob hom tshuaj ua rau muaj kev phiv zoo heev. Hauv qab no yog cov piv txwv ntawm cov kev mob tshwm sim no.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm ntau cov kev mob tshwm sim uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Toujeo, lossis nrog ob hom tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • xeev siab
  • zawv plab
  • mob taub hau
• Yuav tshwm sim nrog Toujeo:
  • hnyav
  • qhov chaw txhaj tshuaj tiv thaiv
  • lipodystrophy (mob los yog mob ntshav siab ntawm thaj chaw txhaj tshuaj)
  • khaus
  • ua pob
  • o hauv koj txhais ceg, pob taws, lossis ko taw
• Yuav tshwm sim nrog ob Soliqua 100/33 thiab Toujeo:
  • cov mob ua pa xws li khaub thuas lossis mob aws
  • hypoglycemia (cov ntshav qab zib tsawg)

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim loj uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Toujeo, lossis nrog ob yam tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • pancreatitis (mob rau hauv qab)
  • raum puas tsuaj
• Yuav tshwm sim nrog Toujeo:
  • ob peb yam kev phiv loj heev
• Yuav tshwm sim nrog ob Soliqua 100/33 thiab Toujeo:
  • kev fab tshuaj hnyav heev
  • Mob ntshav qab zib heev (muaj ntshav qab zib tsawg heev)
  • hypokalemia (qib qis poov tshuaj)

Txij nkawm

Soliqua 100/33 thiab Toujeo tsis tau muab piv rau hauv kev tshawb fawb soj ntsuam. Txawm li cas los xij, kev tshawb fawb ib leeg tau pom tias Toujeo thiab Soliqua 100/33 tuaj yeem txo qis HbA1c thiab yoo cov ntshav qab zib ntau ntau.

• Hauv qhov kev tshawb fawb soj ntsuam, Soliqua 100/33 txo cov hemoglobin A1c (HbA1c) los ntawm 1.1 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 5.7 mg / dL tom qab 30 lub lim tiam ntawm kev kho mob.
• Hauv lwm qhov kev tshawb fawb, Toujeo txo ​​HbA1c los ntawm 0.73 rau 1.42 feem pua ​​thiab yoo cov ntshav qab zib cov ntshav ntau npaum li 18 mus rau 61 mg / dL dhau 26 lub lim tiam ntawm kev kho mob.

Lus khaws xav: Nws yog ib qho tseem ceeb uas yuav tau nco rau hauv siab tias cov tshuaj no yuav txo qis koj li HbA1c lossis ntshav qab zib cov ntshav yuav nyob ntawm ntau yam, nrog rau:

• koj cov piam thaj hauv ntshav thaum koj pib siv tshuaj
• koj kev noj kev haus thiab kev tawm dag zog
• lwm cov tshuaj ntshav qab zib uas koj noj
• koj yuav tsum ua raws li kev kho koj li cas

Cov nqi

Soliqua 100/33 thiab Toujeo yog ob hom tshuaj muaj npe. Tam sim no tsis muaj cov ntawv sau rau ib qho ntawm cov tshuaj. Cov tshuaj muaj npe lag luam feem ntau raug nqi ntau dua li cov generics.

Raws li kev kwv yees los ntawm GoodRx.com, Toujeo feem ntau raug nqi ntau dua li Soliqua 100/33. Tus nqi tiag uas koj yuav them rau ib qho tshuaj twg yog nyob ntawm koj qhov koob tshuaj, koj qhov kev pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj siv.

Soliqua 100/33 vs. Adlyxin

Soliqua 100/33 muaj ob yam tshuaj:

• insulin glargine, uas yog lub vev xaib ntev ntev
• lixisenatide, uas yog nyob rau chav kawm ntawm cov tshuaj hu ua glucagon-zoo li peptide 1 (GLP-1) receptor agonists

Lixisenatide tseem yog cov tshuaj uas muaj nyob hauv Adlyxin. Vim tias Soliqua 100/33 thiab Adlyxin sib koom ua ke, lawv ua haujlwm zoo sib xws hauv lub cev.

Kev Siv

Soliqua 100/33 yog FDA pom zoo rau kev siv nrog kev hloov kev noj haus thiab kev tawm dag zog txhawm rau txhim kho cov ntshav qab zib cov ntshav hauv cov neeg muaj ntshav qab zib hom 2.

Adlyxin yog FDA pom zoo rau siv nrog kev noj haus thiab qoj ib ce txhawm rau txhim kho cov ntshav qab zib cov ntshav hauv cov neeg laus uas muaj ntshav qab zib hom 2.

Cov ntaub ntawv tshuaj thiab kev tswj hwm

Soliqua 100/33 thiab Adlyxin ob qho tib si tuaj ua kua tov rau hauv cov xaum pov tseg. Ob qho tshuaj no yog txhaj rau tus kheej hauv qab daim tawv nqaij (subcutaneous) ib hnub ib zaug.

Soliqua 100/33 cwj mem los hauv ib qhov nyiaj. Txhua tus cwj mem muaj 3 mL ntawm cov tshuaj daws, nrog 100 units ntawm insulin glargine thiab 33 mcg ntawm lixisenatide ib mL. Qhov ntau tshaj plaws hauv kev txhaj tshuaj ib zaug yog 60 units, uas yuav txhais tau tias 60 units ntawm insulin glargine thiab 20 mcg lixisenatide.

Tus cwj mem Adlyxin los ntawm ob qhov sib txawv:

• Tus cwj mem ntsuab Adlyxin muaj 50 mcg / mL hauv 3 mL ntawm kev daws, nrog ib koob tshuaj 10 mcg rau ib zaug txhaj.
• Tus cwj mem burgundy Adlyxin muaj 100 mcg / mL hauv 3 mL ntawm kev daws, nrog ib koob tshuaj 20 mcg rau ib koob.

Phiv thiab txaus ntshai

Soliqua 100/33 thiab Adlyxin ob qho tib si muaj cov tshuaj lixisenatide. Yog li, ob hom tshuaj ua rau muaj kev phiv zoo heev. Hauv qab no yog cov piv txwv ntawm cov kev mob tshwm sim no.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm ntau cov kev mob tshwm sim uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Adlyxin, lossis nrog ob hom tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • cov mob ua pa xws li khaub thuas lossis mob aws
• Yuav tshwm sim nrog Adlyxin:
  • ntuav
  • kiv taub hau
• Yuav tshwm sim nrog ob Soliqua 100/33 thiab Adlyxin:
  • xeev siab
  • zawv plab
  • mob taub hau
  • hypoglycemia (cov ntshav qab zib tsawg)

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim hnyav uas tuaj yeem tshwm sim nrog Soliqua 100/33, nrog Adlyxin, lossis nrog rau ob qho tshuaj (thaum noj ib leeg).

• Muaj peev xwm tshwm sim nrog Soliqua 100/33:
  • hypokalemia (qib qis poov tshuaj)
• Yuav tshwm sim nrog Adlyxin:
  • ob peb yam kev phiv loj heev
• Yuav tshwm sim nrog ob Soliqua 100/33 thiab Adlyxin:
  • kev fab tshuaj hnyav heev
  • Mob ntshav qab zib heev (muaj ntshav qab zib tsawg heev)
  • pancreatitis (mob rau hauv qab)
  • raum puas tsuaj

Txij nkawm

Kev siv ntawm Soliqua 100/33 lossis Adlyxin ua ib qho kev kho mob ib leeg rau cov ntshav qab zib hom 2 tsis tau muab piv rau hauv kev tshawb fawb soj ntsuam.Txawm li cas los xij, kev siv ntawm txhua cov tshuaj cuam tshuam nrog metformin (ib qho tshuaj mob ntshav qab zib hauv qhov ncauj) tau muab coj los sib piv.

Cais kev tshawb fawb thaum siv ib leeg

Hauv cov kev tshawb fawb soj ntsuam txawv, Soliqua 100/33 thiab Adlyxin ob leeg zoo ib leeg los txo kev yoo ntshav cov ntshav qab zib hauv cov neeg muaj ntshav qab zib hom 2.

• Hauv qhov kev tshawb fawb soj ntsuam, Soliqua 100/33 txo cov hemoglobin A1c (HbA1c) los ntawm 1.1 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 5.7 mg / dL tom qab 30 lub lim tiam ntawm kev kho mob.
• Hauv qhov kev tshawb fawb soj ntsuam sib txawv, Adlyxin txo HbA1c los ntawm 0.57 rau 0.71 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 4.48 mus rau 24.56 mg / dL dhau li 24 lub lim tiam ntawm kev kho mob.

Kev sib piv ncaj qha thaum siv nrog metformin

Lwm qhov kev tshawb nrhiav tau sim siv Soliqua 100/33 nrog metformin ncaj qha tiv thaiv kev siv Adlyxin nrog metformin rau cov laus uas muaj ntshav qab zib hom 2. Cov neeg hauv txoj kev tshawb no tau siv yav tas los kho nrog metformin ib leeg, lossis nrog metformin thiab lwm cov tshuaj tiv thaiv ntshav qab zib.

Tom qab 30 lub lis piam, Soliqua 100/33 nrog metformin ua tau zoo dua li Adlyxin nrog metformin. Soliqua 100/33 nrog metformin txo HbA1c los ntawm 1.6 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 59.1 mg / dL. Adlyxin thiab metformin, ntawm lwm yam, txo HbA1c los ntawm 0.9 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 27.2 mg / dL.

Nco tseg: Nws tseem ceeb heev uas yuav tsum nco ntsoov tias zoo li cas ntawm cov tshuaj no yuav txo qis koj li HbA1c lossis ntshav qab zib cov ntshav yuav nyob ntawm ntau yam, nrog rau:

• koj cov piam thaj hauv ntshav thaum koj pib siv tshuaj
• koj kev noj kev haus thiab kev tawm dag zog
• lwm cov tshuaj ntshav qab zib uas koj noj
• koj yuav tsum ua raws li kev kho koj li cas

Cov nqi

Soliqua 100/33 thiab Adlyxin yog ob hom tshuaj muaj npe. Tam sim no tsis muaj cov ntawv sau rau ib qho ntawm cov tshuaj. Cov tshuaj muaj npe lag luam feem ntau raug nqi ntau dua li cov generics.

Raws li kev kwv yees los ntawm GoodRx.com, Adlyxin feem ntau raug nqi ntau dua li Soliqua 100/33. Tus nqi tiag uas koj yuav them rau ib qho tshuaj twg yog nyob ntawm koj qhov ntau npaum li cas, koj hom kev pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj siv.

Thaum lub Tsib Hlis 2020, Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau pom zoo tias qee cov neeg tsim cov tshuaj metformin ncua kev tso tawm tshem qee cov ntsiav tshuaj ntawm Tebchaws Meskas. Qhov no yog vim tias qhov tsis tsim nyog ntawm cov teeb meem carcinogen (tus neeg sawv cev mob qog nqaij hlav cancer) tau pom hauv qee cov tshuaj ncua metformin. Yog tias koj tam sim no noj cov tshuaj no, hu rau koj tus kws kho mob. Lawv yuav qhia seb koj yuav tsum noj koj cov tshuaj txuas ntxiv lossis yog koj xav tau daim ntawv yuav tshuaj tshiab.

Soliqua 100/33 siv

Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau pom zoo rau cov tshuaj xws li Soliqua 100/33 txhawm rau kho qee yam mob. Soliqua 100/33 yog FDA pom zoo rau kev siv nrog kev hloov kev noj haus thiab kev tawm dag zog txhawm rau txhim kho cov ntshav qab zib cov ntshav hauv cov neeg muaj ntshav qab zib hom 2.

Hauv 30 lub lis piam kev tshawb fawb txog cov neeg uas tau txais kev kho mob los ntawm ib hom basal insulin (xws li insulin glargine), Soliqua 100/33 tau pom tias muaj txiaj ntsig. Nws txo hemoglobin A1c (HbA1c) los ntawm 1.1 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 5.7 mg / dL.

Kev tshawb nrhiav 30-lub lim tiam tau tsom mus rau cov tib neeg uas tau siv tshuaj metformin ib leeg, lossis nrog metformin thiab lwm qhov tshuaj mob ntshav qab zib. Rau cov neeg hauv txoj kev tshawb no, Soliqua 100/33 thiab metformin txo lawv cov HbA1c los ntawm 1.6 feem pua ​​thiab yoo cov ntshav qab zib ntau ntau los ntawm 59.1 mg / dL.

Soliqua 100/33 siv nrog lwm yam tshuaj

Soliqua 100/33 tuaj yeem siv ib leeg los yog ua ke nrog lwm cov tshuaj los txhim kho cov ntshav qab zib hauv cov neeg muaj ntshav qab zib hom 2. Hauv kev kho mob ntshav qab zib, nws ib txwm muaj ntau dua ib qho kev siv tshuaj los tswj tswj qib ntshav qab zib yog tias ib qho tshuaj ib leeg tsis txhim kho cov ntshav qab zib kom txaus.

Piv txwv ntawm cov tshuaj uas tuaj yeem siv nrog Soliqua 100/33 suav nrog:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• tshuaj pleev qhov muag (Amaryl)
• glipizide (Glucotrol)
• glyburide (DiaBeta, Glynase)
• metformin (Glucophage, Glumetza, Riomet)
• pioglitazone (Actos)

Soliqua 100/33 thiab cawv

Zam txhob haus cawv ntau thaum haus cov tshuaj Soliqua 100/33. Kev haus dej cawv tuaj yeem hloov pauv koj cov ntshav qab zib hauv cov ntshav thiab ua rau koj muaj kev mob ntshav qab zib tsawg (muaj ntshav qab zib hauv lub cev) thiab kab mob pancreatitis (mob ua paug).

Yog tias koj haus cawv, tham nrog koj tus kws kho mob txog kev haus dej haus cawv muaj kev nyab xeeb rau koj npaum li cas.

Soliqua 100/33 kev sib txuam

Soliqua 100/33 tuaj yeem cuam tshuam nrog ntau lwm yam tshuaj. Nws tuaj yeem cuam tshuam nrog qee yam tshuaj ntxiv nrog rau qee yam zaub mov.

Kev sib cuam tshuam sib txawv tuaj yeem ua rau txawv txav. Piv txwv li, qee tus tuaj yeem cuam tshuam nrog cov tshuaj ua haujlwm zoo li cas, thaum lwm tus tuaj yeem ua rau muaj kev mob tshwm sim ntau ntxiv.

Soliqua 100/33 thiab lwm yam tshuaj noj

Hauv qab no yog cov npe tshuaj uas muaj peev xwm sib cuam tshuam nrog Soliqua 100/33. Daim ntawv no tsis muaj tag nrho cov tshuaj uas yuav cuam tshuam nrog Soliqua 100/33.

Ua ntej noj tshuaj Soliqua 100/33, nco ntsoov qhia koj tus kws kho mob thiab kws muag tshuaj txog txhua yam tshuaj noj, yuav tom kiab khw, thiab lwm yam tshuaj uas koj noj. Kuj tseem qhia rau lawv txog cov vitamins, tshuaj ntsuab, thiab tshuaj siv uas koj siv. Sib qhia cov ntaub ntawv no tuaj yeem pab koj kom tsis txhob muaj kev cuam tshuam.

Yog tias koj muaj lus nug txog kev sib txuam nrog tshuaj uas yuav cuam tshuam koj, nug koj tus kws kho mob lossis kws muag tshuaj.

Lwm yam tshuaj kho ntshav qab zib

Kev noj tshuaj Soliqua 100/33 nrog rau lwm cov tshuaj kho ntshav qab zib tuaj yeem ua rau cov ntshav qab zib qis ntau ntau thiab ua rau koj muaj kev pheej hmoo hypoglycemia (cov ntshav qab zib qis). Yog tias koj noj ib qho ntawm cov tshuaj no, koj yuav tsum tau soj ntsuam koj cov ntshav qab zib kom ntau. Tsis tas li, koj tus kws kho mob yuav xav hloov koj qhov ntau npaum li cas ntawm Soliqua 100/33.

Piv txwv ntawm cov tshuaj kho ntshav qab zib muaj xws li:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• glyburide (DiaBeta, Glynase, Micronase)
• tshuaj pleev qhov muag (Amaryl)
• glipizide (Glucotrol)
• insulins noj mov-sijhawm (Humalog, Novolog)
• metformin (Glucophage)
• pawg (Starlix)
• kho siab (Prandin)

Ntxiv rau, siv cov Soliqua 100/33 nrog cov tshuaj mob ntshav qab zib hu ua thiazolidinediones (TZDs) tuaj yeem ua rau kom cov kua dej tsis qab. Nws kuj tseem tuaj yeem ua kom koj qhov kev pheej hmoo ntawm lub plawv tsis zoo lossis ua rau cov tsos mob ntawm lub plawv tsis ua haujlwm (saib cov lus ceeb toom hauv qab). Cov ua piv txwv ntawm cov tshuaj no suav nrog:

• pioglitazone (Actos)
• rosiglitazone (Avandia)

Yog tias koj tab tom noj TZD, nrog koj tus kws kho mob tham ua ntej pib Soliqua 100/33. Yog tias koj tus kws kho mob pom zoo koj siv TZD thaum siv Soliqua 100/33, nco ntsoov saib xyuas cov tsos mob ntawm lub plawv nres. Yog tias koj txhim kho lub plawv tsis ua haujlwm, koj tus kws kho mob tuaj yeem txo qhov koob tshuaj ntawm koj TZD lossis koj tsum tsum tsis noj.

Cov tsos mob ntawm lub plawv tsis zoo tuaj yeem suav nrog:

• teeb meem ua pa
• o hauv cov ceg, pob taws, thiab taw
• lub plawv dhia ceev lossis ceev
• mob hauv siab

Qhia tshuaj ntshav siab

Kev noj cov tshuaj Soliqua 100/33 nrog rau qee cov tshuaj muaj ntshav siab tuaj yeem ua rau cov ntshav qab zib ntshav qab zib ntau ntau thiab ua rau koj muaj kev pheej hmoo hypoglycemia (cov ntshav qab zib tsawg). Yog tias koj noj ib qho ntawm cov tshuaj no, koj yuav tsum tau soj ntsuam koj cov ntshav qab zib kom ntau. Tsis tas li, koj tus kws kho mob yuav xav hloov koj qhov ntau npaum li cas ntawm Soliqua 100/33.

Piv txwv ntawm cov tshuaj ntshav siab uas tuaj yeem ua rau muaj kev pheej hmoo ntawm cov ntshav qab zib thaum noj nrog Soliqua 100/33 suav nrog:

• angiotensin-hloov ua enzyme (ACE) inhibitors, xws li:
• benazepril (Lotensin)
• captopril
• enalapril (Vasotec)
• lisinopril (Zestril)
• angiotensin II receptor blockers (ARBs), xws li:
• valsartan (Diovan)
• candesartan (Atacand)
• Irbesartan (Avapro)
• losartan (Cozaar)
• olmesartan (Benicar)

Lwm cov tshuaj noj ntshav tuaj yeem tiv thaiv cov tsos mob ntawm cov ntshav qab zib qis heev. Cov tshuaj no tseem tuaj yeem nce lossis txo qis npaum li cas Soliqua 100/33 yog ntawm kev txo cov ntshav qab zib kom qis. Yog tias koj noj cov tshuaj no nrog Soliqua 100/33, koj yuav tsum kuaj xyuas koj cov ntshav qab zib kom ntau. Tsis tas li, koj tus kws kho mob yuav xav hloov koj qhov ntau npaum li cas ntawm Soliqua 100/33.

Piv txwv ntawm cov tshuaj tiv thaiv kev mob ntshav siab uas tuaj yeem npog qhov tshwm sim ntawm cov ntshav siab lossis cuam tshuam rau Soliqua 100/33 ua haujlwm tau zoo npaum li cas suav nrog:

• clonidine (Catapres)
• metoprolol (Lopressor, Toprol-XL)
• atenolol (Tenormin)

Lwm yam tshuaj uas tej zaum yuav zais qhov tsis muaj ntshav qab zib

Qee cov tshuaj tuaj yeem npog qhov cim thiab cov tsos mob ntawm cov ntshav qab zib qis heev. Yog tias koj noj cov tshuaj no, tej zaum koj yuav tau soj ntsuam koj cov ntshav qab zib kom ntshav ntau dua. Tsis tas li, koj tus kws kho mob yuav xav hloov koj qhov ntau npaum li cas ntawm Soliqua 100/33.

Piv txwv ntawm cov tshuaj muaj xws li:

• albuterol (ProAir, Proventil, Ventolin)
• guanethidine
• reserpine

Lwm yam tshuaj uas tuaj yeem txo cov ntshav qab zib kom tsawg

Kev noj cov tshuaj Soliqua 100/33 nrog rau lwm yam tshuaj noj tuaj yeem ua rau muaj ntshav qab zib cov ntshav qab zib tsawg thiab ua rau koj muaj kev pheej hmoo hypoglycemia (cov ntshav qab zib tsawg). Yog tias koj noj ib qho ntawm cov tshuaj no, koj yuav tsum tau soj ntsuam koj cov ntshav qab zib kom ntau. Tsis tas li, koj tus kws kho mob yuav xav hloov koj qhov ntau npaum li cas ntawm Soliqua 100/33.

Piv txwv ntawm cov tshuaj muaj xws li:

• disopyramide (Norpace)
• qee cov tshuaj siv roj hauv siab, xws li fenofibrate (Tricor, Triglide) thiab gemfibrozil (Lopid)
• qee yam tshuaj tua kab mob, xws li fluoxetine (Prozac, Sarafem) thiab selegiline (Emsam, Zelapar)
• octreotide (Sandostatin)
• sulfamethoxazole-trimethoprim (Bactrim, Septra)

Lwm yam tshuaj uas ua rau koj cov ntshav qab zib kom ntau ntau

Qee cov tshuaj muaj peev xwm nce qib ntshav qab zib hauv koj lub cev. Yog tias koj noj cov tshuaj no, tej zaum koj yuav tsum tau soj ntsuam koj cov ntshav qab zib kom ntau kom ntau kom tiv thaiv hyperglycemia (ntshav qab zib cov ntshav qab zib). Tsis tas li, koj tus kws kho mob yuav xav hloov koj qhov ntau npaum li cas ntawm Soliqua 100/33.

Piv txwv ntawm cov tshuaj muaj xws li:

• albuterol (ProAir, Proventil, Ventolin)
• qee yam tshuaj tua kab mob, xws li atazanavir (Reyataz) thiab lopinavir / ritonavir (Kaletra)
• qee cov tshuaj steroids, xws li budesonide (Entocort EC, Pulmicort, Uceris), prednisone, thiab fluticasone (Flonase, Flovent)
• qee cov diuretics, xws li chlorothiazide (Diuril) thiab hydrochlorothiazide (Microzide)
• qee yam tshuaj tiv thaiv kev ntxhov siab, xws li clozapine (Clozaril, Fazaclo) thiab olanzapine (Zyprexa)
• qee cov tshuaj hormones, xws li danazol (Danazol), levothyroxine (Levoxyl, Synthroid) thiab somatropin (Genotropin)
• glucagon (GlucaGen)
• niacin (Niaspan, Slo-Niacin, lwm tus)
• tshuaj tiv thaiv kom txhob muaj me nyuam (tshuaj txwv)

Cov tshuaj uas ua kom nce lossis txo qhov tshwm sim ntawm Soliqua 100/33

Qee cov tshuaj muaj peev xwm cuam tshuam li cas Soliqua 100/33 ua haujlwm hauv koj lub cev. Yog tias koj noj cov tshuaj no, tej zaum koj yuav tau soj ntsuam koj cov ntshav qab zib kom ntshav ntau dua. Tsis tas li, koj tus kws kho mob yuav xav hloov koj qhov ntau npaum li cas ntawm Soliqua 100/33.

Piv txwv ntawm cov tshuaj muaj xws li:

• albuterol (ProAir, Proventil, Ventolin)
• lithium

Soliqua 100/33 thiab tshuaj ntsuab thiab tshuaj ntxiv

Kev noj cov tshuaj Soliqua 100/33 nrog qee yam tshuaj ntsuab lossis tshuaj noj muaj peev xwm ua rau koj muaj kev pheej hmoo (ntshav qab zib hauv cov ntshav qis). Piv txwv ntawm cov no suav nrog:

• alpha-lipoic kua qaub
• banaba
• iab iab
• chromium
• kev dhia paj paws
• prickly pear cactus
• dawb mulberry

Yuav ua li cas Soliqua 100/33 ua haujlwm

Soliqua 100/33 pab txhim kho cov ntshav qab zib cov ntshav hauv cov neeg muaj ntshav qab zib hom 2.

Tshuaj insulin cuam tshuam li cas cov ntshav qab zib

Nquag, thaum koj noj zaub mov, koj lub cev tso tawm ib yam tshuaj hu ua insulin. Cov piam thaj (qab zib) los ntawm cov zaub mov xa mus rau koj cov ntshav, thiab cov insulin pab thauj nws mus rau hauv cov hlwb ntawm koj lub cev. Cov qog ntawd yuav hloov cov piam thaj rau hauv lub zog.

Cov neeg muaj ntshav qab zib hom 2 feem ntau muaj tshuaj tiv thaiv insulin. Qhov no txhais tau tias lawv lub cev tsis teb rau insulin txoj kev uas nws yuav tsum tau. Sij hawm dhau mus, cov neeg muaj ntshav qab zib hom 2 tej zaum tseem tuaj yeem nres tsim insulin tsis txaus.

Thaum koj lub cev tsis teb rau insulin txoj kev uas nws yuav tsum tau, lossis yog nws tsis tsim cov insulin txaus, qhov no ua rau muaj teeb meem. Cov hlwb ntawm koj lub cev yuav tsis tuaj yeem txais cov piam thaj lawv yuav tsum ua haujlwm kom raug.

Tsis tas li, koj yuav muaj cov piam thaj ntau hauv koj cov ntshav. Qhov no yog hu ua hyperglycemia (ntshav qab zib hauv ntshav siab). Muaj cov piam thaj ntau hauv koj cov ntshav tuaj yeem ua rau koj lub cev thiab cov plab hnyuv siab raum, nrog rau koj lub qhov muag, lub plawv, lub raum thiab lub raum.

Dab tsi Soliqua 100/33 ua

Soliqua 100/33 muaj ob lub tshuaj. Cov no yog cov tshuaj insulin glargine, uas yog cov insulin ntev ntev, thiab lixisenatide, uas yog glucagon-zoo li peptide 1 (GLP-1) receptor agonist.

Insulin glargine ua haujlwm nyob rau hauv ib txoj kev: nws txo qis koj cov piam thaj hauv ntshav los ntawm kev mus nyob nrog koj cov ntshav hauv koj lub hlwb.

Lixisenatide ua haujlwm nyob rau hauv peb txoj kev. Ua ntej, nws nce insulin ntau ntxiv koj lub cev ua. Qhov kev nce insulin no pab txav ntau dua cov piam thaj hauv koj cov hlab ntshav thiab mus rau hauv koj lub hlwb. Qhov thib ob, nws ua rau koj lub plab tsis tsaug zog ntxiv tom qab noj mov tas, ua rau koj lub siab ntev ntev. Thiab qhov peb, nws qhia koj lub siab kom tso cov piam thaj tsawg hauv koj cov ntshav.

Yuav siv sijhawm ntev npaum li cas ua haujlwm?

Soliqua 100/33 pib ua haujlwm tom qab koj txhaj tshuaj. Txawm li cas los xij, nws ncav cuag nws cov txiaj ntsig siab tshaj plaws txog 2.5 mus rau 3 teev tom qab kev txhaj ib zaug.

Soliqua 100/33 thiab cev xeeb tub

Cov ntaub ntawv kawm muaj txwv rau kev siv Soliqua 100/33 thaum cev xeeb tub hauv tib neeg. Txawm li cas los xij, kev tshawb fawb tsiaj pom tias nws yuav muaj kev pheej hmoo ntawm kev yug menyuam nrog siv cov lixisenatide thaum cev xeeb tub. Lixisenatide yog ib qho ntawm cov tshuaj muaj nyob hauv Soliqua 100/33. Yog li, Soliqua 100/33 tsuas yog siv thaum cev xeeb tub yog tias muaj txiaj ntsig ntau dua qhov muaj peev xwm txaus ntshai.

Yog tias koj xeeb tub lossis npaj yuav muaj menyuam, nrog koj tus kws kho mob tham txog cov kev pheej hmoo thiab cov txiaj ntsig ntawm kev siv Soliqua 100/33 thaum cev xeeb tub.

Soliqua 100/33 thiab pub niam mis

Nws tsis paub yog tias Soliqua 100/33 xa mus rau niam cov kua mis. Ua ntej pub niam mis, koj yuav tsum sab laj nrog koj tus kws kho mob txog cov kev pheej hmoo thiab txiaj ntsig ntawm kev noj cov tshuaj no thaum pub niam mis.

Cov lus nug nquag hais txog Soliqua 100/33

Nov yog cov lus teb rau qee cov lus nug nquag nug txog Soliqua 100/33.

Puas yog Soliqua 100/33 ua rau hnyav dua?

Hauv kev sim tshuaj, Soliqua 100/33 tsis pom pom tias yuav ua rau koj qhov hnyav nce. Qhov tseeb, hauv ib qhov kev tshawb fawb soj ntsuam, cov neeg uas siv tshuaj Soliqua 100/33 rau 30 lub lis piam poob txog 1.5 phaus.

Nws yog qhov nthuav kom nco ntsoov tias cov tshuaj ib leeg muaj nyob hauv Soliqua 100/33 zoo li muaj cov teebmeem sib txawv ntawm qhov hnyav. Ib qho ntawm cov tshuaj yog cov tshuaj insulin glargine, uas yog lub cev insulin ntev ntev. Feem ntau, cov tshuaj uas muaj cov tshuaj insulin tau txuas nrog lub cev qhov hnyav.

Txawm li cas los xij, lwm cov tshuaj hauv Soliqua 100/33 yog hu ua lixisenatide, uas yog glucagon zoo li peptide 1 (GLP-1) receptor agonist. Cov tshuaj hauv GLP-1 cov tshuaj qhia tau pom tias qhov poob phaus yog qhov tshwm sim nyob rau hauv ntau qhov kev tshawb fawb soj ntsuam.

Yog tias koj txhawj xeeb txog cov teebmeem uas Soliqua 100/33 tuaj yeem ua rau koj qhov hnyav, tham nrog koj tus kws kho mob.

Puas yog Soliqua 100/33 insulin?

Yog lawm, Soliqua 100/33 muaj cov tshuaj insulin. Soliqua 100/33 yog tsim los ntawm ob lub tshuaj, ib qho yog insulin glargine, ua haujlwm ntev insulin.

Qhov tshuaj thib ob yog lixisenatide, uas yog glucagon zoo li peptide 1 (GLP-1) receptor agonist.

Puas yog Soliqua 100/33 ua haujlwm ntev?

Yog lawm. Soliqua 100/33 muaj ob qho tshuaj nquag. Ib qho ntawm cov no yog cov tshuaj insulin glargine, uas yog cov insulin ntev ntev.

Puas yuav Soliqua 100/33 tuaj yeem siv los kho mob ntshav qab zib hom 1?

Tsis yog, Soliqua 100/33 yuav tsum tsis txhob siv los kho tus mob ntshav qab zib hom 1. Soliqua 100/33 tseem tsis tau kawm lossis pom zoo los ntawm Food and Drug Administration los kho qhov mob ntawd. Nws tsuas yog pom zoo los kho mob ntshav qab zib hom 2 xwb.

Soliqua 100/33 lus ceeb toom

Ua ntej noj tshuaj Soliqua 100/33, nrog koj tus kws kho mob tham txog koj li keeb kwm kev noj qab haus huv. Soliqua 100/33 tuaj yeem tsis haum rau koj yog tias koj muaj qee yam mob. Cov no suav nrog:

• Mob raumCov. Yog tias koj muaj kab mob hauv lub raum, noj cov tshuaj Soliqua 100/33 yuav ua rau koj tus mob hnyav dua. Yog koj tus mob loj tuaj, koj yuav tsum tsum tsis txhob noj tshuaj Soliqua 100/33. Tsis txhob noj cov tshuaj no yog tias koj muaj mob raum.
• Ua kom lub plab zom movCov. Lixisenatide, ib qho tshuaj nyob hauv Soliqua 100/33, ua rau qeeb ntawm kev txiav txim ntawm koj cov leeg plab. Yog tias koj muaj mob gastroparesis, uas txhais tau tias koj lub cev zom zaub mov qeeb, noj Soliqua 100/33 yuav ua rau koj lub cev tsis zoo. Cov neeg muaj mob gastroparesis heev yuav tsum tsis txhob noj cov tshuaj no.
• Mob caj dab los yog teeb meem, lossis haus cawv tsis meejCov. Soliqua 100/33 tuaj yeem ua rau koj muaj kev pheej hmoo ntawm pancreatitis. Tej zaum koj yuav muaj feem ua mob pancreatitis yog tias koj muaj keeb kwm ua ntej, mob qa, lub pob zeb rau pob zeb, lossis quav dej quav cawv. Yog tias koj muaj keeb kwm ntawm cov teeb meem no, tham nrog koj tus kws kho mob txog seb Soliqua 100/33 puas zoo rau koj.

Soliqua 100/33 overdose

Noj ntau dhau ntawm cov tshuaj no tuaj yeem ua rau koj muaj kev phom sij txaus ntshai.

Tshuav cov tsos mob

Cov tsos mob ntawm kev noj haus ntau dhau muaj xws li:

• Mob ntshav qab zib heev (mob ntshav qab zib tsawg heev), uas tuaj yeem ua rau tshee, ntxhov siab thiab tsis meej pem
• hypokalemia (muaj poov tshuaj qis), uas tuaj yeem ua rau qaug zog, cem quav, thiab mob leeg
• lub plab zom mov teeb meem, uas tuaj yeem ua rau mob raws plab, xeev siab thiab ntuav

Dab tsi yog qhov ua txhaum cai dhau

Yog koj xav tias koj tau noj ntau dhau ntawm cov tshuaj no, hu rau koj tus kws kho mob lossis nrhiav kev qhia los ntawm American Association of Poison Control Center ntawm 800-222-1222 lossis hauv lawv cov twj online. Tab sis yog tias koj cov tsos mob hnyav, hu 911 lossis mus rau chav kho mob ze tshaj plaws tam sim ntawd.

Soliqua 100/33 tas sij hawm thiab cia

Thaum Soliqua 100/33 tau tso tawm los ntawm lub tsev muag tshuaj, tus kws muag tshuaj yuav ntxiv hnub tas sij hawm rau cov npe ntawm lub khob. Hnub no ib txwm muaj ib xyoos suav txij hnub pib muab tshuaj rau.

Lub hom phiaj ntawm cov hnub tas sij hawm no yog kom tau txais txiaj ntsig zoo ntawm kev noj tshuaj nyob rau lub sijhawm no. Txoj cai tam sim no ntawm Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) yog kom tsis txhob siv cov tshuaj uas tas sij hawm.

Kev noj tshuaj ntev npaum li cas tuaj yeem nyob ntawm ntau yam, nrog rau seb yuav khaws cia cov tshuaj thiab cia. Muab koj lub Soliqua 100/33 npiv tso rau hauv koj lub tub yees, ntawm qhov txias li 36 ° F thiab 46 ° F (2 ° C thiab 8 ° C). Tsis txhob cia li txav los hauv koj cov npiv.

Tom qab siv thawj zaug ntawm txhua tus cwj mem, koj tuaj yeem khaws nws hauv chav sov (77 ° F / 25 ° C), tab sis nco ntsoov tiv thaiv nws ntawm lub teeb. Pov tseg txhua tus cwj mem tom qab 28 hnub los ntawm nws thawj zaug siv.

Yog tias koj tsis tau siv cov tshuaj uas dhau lub caij nyoog tas sijhawm, tham nrog koj tus kws muag tshuaj txog seb koj puas tseem tuaj yeem siv ntxiv.

Cov ntaub ntawv tshaj lij rau Soliqua 100/33

Cov ntaub ntawv hauv qab no yog muab rau cov kws kho mob thiab lwm tus kws kho mob.

Cov Khoom Qhia

Soliqua 100/33 yog FDA pom zoo rau kev siv nrog kev noj haus thiab kev tawm dag zog txhawm rau txhim kho glycemic tswj hauv cov neeg laus uas muaj hom 2 mob ntshav qab zib mellitus.

Mechanism ntawm kev ua

Soliqua 100/33 yog kev sib xyaw ua ke ntawm cov tshuaj insulin glargine (lub hauv paus insulin analog) thiab lixisenatide (ib qho zoo li glucagon-zoo li peptide 1 [GLP-1] receptor agonist).

Insulin glargine txo qis ntshav qabzib ntau dua los ntawm kev nce cov piam thaj hauv qabzib thiab txo cov piam thaj hauv siab. Lixisenatide txo cov ntshav qabzib ntau ntau los ntawm kev ua kom insulin tso tsawg, txo qis glucagon tso zis, thiab ua kom lub plab zom mov.

Pharmacokinetics thiab cov metabolism

Cov insulin glargine-rau-lixisenatide piv tsis muaj kev cuam tshuam rau cov pharmacokinetics ntawm ib qho twg.

Cov tshuaj insulin glargine tsis muaj lub ncov thiab qhov tob tob nyob rau ntawm lub carboxyl terminus ntawm cov saw B hauv qhov subcutaneous depot.

Lub sijhawm rau max qhov siab rau lixisenatide yog li 2.5 mus rau 3 teev. Lixisenatide muaj 55 feem pua ​​nqi khi protein sib luag thiab raug tshem tawm ntawm cov zis thiab cov roj ntsha tiv thaiv kab mob. Txhais tau tias ib nrab-lub neej yog li 3 teev.

Cov Yuav Tsum Tau Ua

Soliqua 100/33 yog contraindicated rau hauv cov neeg mob:

• thaum lub caij nplooj zeeg hypoglycemic
• nrog cov keeb kwm ntawm kev mob siab dhau mus rau insulin glargine lossis lixisenatide

Cia

Soliqua 100/33 cwjmem yuav tsum muab cia rau hauv tub yees, ntawm qhov kub txog 36 ° F thiab 46 ° F (2 ° C thiab 8 ° C), tab sis tsis txhob cia kom khov. Tom qab siv thawj zaug, cwjmem tuaj yeem khaws cia hauv chav sov li 77 ° F (25 ° C). Lawv yuav tsum muaj kev tiv thaiv los ntawm lub teeb. Pov tseg tus cwj mem tom qab 28 hnub los ntawm kev siv thawj zaug.

Kev tsis lees paub: MedicalNewsToday tau ua txhua yam kom paub tseeb tias txhua yam ntaub ntawv yog qhov tseeb, raug, thiab dhau-hnub. Txawm li cas los xij, cov kab lus no yuav tsum tsis txhob siv los hloov chaw rau qhov kev paub thiab kev paub ntawm tus neeg muaj ntawv tso cai kho mob. Koj yuav tsum tau sab laj nrog koj tus kws kho mob lossis lwm tus kws saib xyuas kev noj qab haus huv ua ntej noj tshuaj. Cov ntaub ntawv tshuaj muaj nyob ntawm no yuav raug hloov thiab tsis yog npaj rau txhua txoj kev siv, cov lus qhia, kev ceev faj, ceeb toom, kev cuam tshuam nrog tshuaj, kev fab tshuaj, lossis muaj kev cuam tshuam tsis zoo. Qhov tsis muaj lus ceeb toom lossis lwm cov ntaub ntawv rau kev muab tshuaj tsis qhia tias kev sib txuam tshuaj lossis tshuaj muaj kev nyab xeeb, siv tau, lossis tsim nyog rau txhua tus neeg mob lossis txhua qhov siv tshwj xeeb.