Antiphospholipid Syndrome: Nws yog dab tsi, Ua rau thiab kho mob

Zoo Siab

• Cov cim tseem ceeb thiab cov tsos mob
• Dab tsi ua rau tus mob
• Yuav kuaj li cas
• Yuav kho tus mob li cas
• Kev kho mob thaum cev xeeb tub

Antiphospholipid Tshuaj Tua Kab Mob, kuj tseem paub Ntxawm los yog tsuas yog SAF lossis SAAF, yog qhov tsis tshua muaj kab mob autoimmune uas yooj yim los ntawm kev yooj yim rau kev ua rau lub plab thiab cov hlab ntsha uas cuam tshuam nrog cov ntshav txhaws, uas tuaj yeem ua rau mob taub hau, ua pa nyuaj thiab plawv nres, piv txwv.

Raws li qhov ua rau, SAF tuaj yeem raug faib ua peb yam tseem ceeb:

1. Thawj, nyob rau hauv uas tsis muaj kev tshwj xeeb;
2. Thib Ob, uas tshwm sim raws li kev rau txim ntawm lwm tus kab mob, thiab feem ntau cuam tshuam nrog Systemic Lupus Erythematosus. APS Secondary kuj tseem tuaj yeem tshwm sim, txawm hais tias nws tsis tshua muaj, kev cuam tshuam nrog lwm cov kab mob autoimmune, xws li scleroderma thiab mob caj dab, piv txwv;
3. Kev Puas Tsuaj, uas yog hom loj tshaj ntawm APS uas thrombi tau tsim hauv tsawg kawg 3 qhov chaw sib txawv hauv tsawg dua 1 lub lis piam.

APS tuaj yeem tshwm sim tsis hais lub hnub nyoog li cas thiab hauv ob hom poj niam, txawm li cas los xij nws muaj ntau dua rau cov poj niam hnub nyoog 20 thiab 50 xyoo. Kev kho mob yuav tsum tau tsim los ntawm cov kws kho mob feem ntau lossis tus kws kho pob txha thiab muaj lub hom phiaj los tiv thaiv qhov tsim ntawm thrombi thiab tiv thaiv kom tsis txhob muaj teeb meem, tshwj xeeb tshaj yog thaum tus poj niam cev xeeb tub.

Cov cim tseem ceeb thiab cov tsos mob

Cov cim tseem ceeb thiab cov tsos mob ntawm APS cuam tshuam nrog kev hloov pauv ntawm cov txheej txheem coagulation thiab qhov tshwm sim ntawm thrombosis, qhov tseem ceeb yog:

• Kev mob hauv siab;
• Ua pa nyuaj;
• Mob taub hau;
• Xeev siab;
• O rau sab sauv lossis sab saud;
• Txo cov khoom platelets;
• Qhov tshwm sim muaj neeg raug rho tawm lossis hloov chaw ntawm lub cev, tsis muaj qhov ua rau pom tseeb.

Ntxiv rau, cov neeg kuaj mob APS feem ntau yuav muaj teeb meem lub raum, mob plawv lossis mob hlab ntsha tawg, piv txwv li, vim muaj kev tsim lub thrombi uas cuam tshuam nrog cov ntshav ncig, hloov cov ntshav mus txog hauv cov kabmob. Nkag siab txog tus mob thrombosis yog dab tsi.

Dab tsi ua rau tus mob

Antiphospholipid Antibody Syndrome yog ib yam mob autoimmune, uas txhais tau hais tias lub cev tiv thaiv kab mob tua nws tus kheej hauv cov hlwb hauv lub cev. Hauv qhov no, lub cev tsim cov tshuaj tua kabmob (antiphospholipid antibodies) uas tawm tsam cov phospholipids tam sim no nyob hauv cov roj ntsha, uas ua rau nws cov ntshav tau yooj yim los co thiab tsim kom muaj thrombi.

Cov laj thawj tshwj xeeb vim li cas cov tiv thaiv kab mob ua kom lub cev tiv thaiv kab mob no tseem tsis tau paub, tab sis nws paub tias nws yog ib qho kev mob tshwm sim ntau dua rau cov neeg uas muaj lwm yam kab mob autoimmune, xws li Lupus, piv txwv.

Yuav kuaj li cas

Kev kuaj mob Antiphospholipid Antibody Syndrome yog txhais los ntawm tsawg kawg ib qhov kev kuaj mob thiab kuaj ntshav, uas yog, qhov pom ntawm tus yam ntxwv ntawm tus kab mob thiab kev kuaj mob tsawg kawg yog ib tus mob autoantibody hauv cov ntshav.

Ntawm cov kev kho mob uas tus kws kho mob txiav txim siab yog cov xwm txheej ntawm txoj hlab ntshav lossis txoj hlab ntshav ntawm txoj hlab ntsws, tshwm sim ntawm kev rho menyuam, kev yug menyuam ntxov, kev mob autoimmune thiab muaj qhov pheej hmoo txaus rau thrombosis. Cov kab mob hauv kev kho mob no yuav tsum muaj pov thawj los ntawm kev kos duab lossis kuaj sim.

Hais txog kev ntsuas hauv chav kuaj yog qhov tsawg kawg ib qho ntawm cov tshuaj tiv thaiv kev tiv thaiv kabmob (antiphospholipid antibody), xws li:

• Lupus anticoagulant (AL);
• Anticardiolipin;
• Anti beta2-glycoprotein 1.

Cov tshuaj tiv thaiv no yuav tsum tau ntsuas nyob rau ob zaug sib txawv, nrog lub sijhawm tsawg kawg 2 hlis.

Txog kev kuaj pom tias muaj txiaj ntsig zoo rau APS, nws yog qhov tsim nyog tias ob qho qauv pov thawj dhau los ntawm kev soj ntsuam ua ob zaug nrog kev ncua sij hawm tsawg kawg 3 hlis.

Yuav kho tus mob li cas

Txawm hais tias tsis muaj ib qho kev kho mob muaj peev xwm kho tau tus mob APS, nws muaj peev xwm txo kev pheej hmoo ntawm txhaws thiab, yog li ntawd, qhov tshwm sim ntawm cov teeb meem xws li thrombosis lossis infarction, los ntawm kev siv ntau dhau ntawm cov tshuaj anticoagulant, xws li Warfarin, uas yog rau qhov ncauj siv, lossis Heparin, uas yog rau tso cov leeg mob.

Feem ntau, cov neeg mob APS uas tau txais kev kho mob nrog anticoagulants muaj peev xwm ua lub neej tsis zoo kiag li, nws tsuas yog ib qho tseem ceeb kom muaj kev teem sijhawm nrog tus kws kho mob txhawm rau kho qhov tshuaj ntawm cov tshuaj, thaum tsim nyog.

Txawm li cas los xij, txhawm rau kom muaj kev vam meej ntawm kev kho mob, nws tseem tseem ceeb kom tsis txhob muaj qee tus cwj pwm uas yuav cuam tshuam cov tshuaj anticoagulants, ib yam li kev noj zaub mov nrog cov vitamin K, xws li zaub ntsuab, zaub qhwv lossis zaub cob pob, piv txwv. Tshawb xyuas lwm yam kev ceev faj koj yuav tsum ua thaum siv cov tshuaj tiv thaiv.

Kev kho mob thaum cev xeeb tub

Hauv qee kis tshwj xeeb ntxiv, xws li thaum cev xeeb tub, tus kws kho mob yuav pom zoo kom kho nrog Heparin cuam tshuam nrog Aspirin lossis tshuaj txhaj tiv thaiv kab mob Immunoglobulin, txhawm rau tiv thaiv qhov tshwm sim ntawm cov teeb meem xws li rho menyuam, piv txwv.

Nrog rau kev kho mob kom zoo, muaj feem ntau yuav ua rau tus poj niam cev xeeb tub nrog APS yuav muaj lub cev xeeb tub ib txwm, txawm li cas los xij nws yog qhov yuav tsum tau saib xyuas los ntawm tus kws saib xyuas menyuam mob, vim tias nws yuav muaj kev phom sij ntau dua, ua ntej yug menyuam lossis yug menyuam ntxov. Kawm paub yuav ua li cas kom paub txog cov tsos mob ntawm preeclampsia.