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Henoch-Schonlein Purpura: Visual Explanation for Students
Daim Duab: Henoch-Schonlein Purpura: Visual Explanation for Students

Zoo Siab

Dab tsi yog purpura?

Purpura, tseem hu ua ntshav kis lossis mob ntshav lossis tawv nqaij, yog hais txog ntshav-xim me ntsis uas tuaj yeem pom ntau dua ntawm daim tawv nqaij. Cov pob ntawd kuj tseem tuaj yeem tshwm rau tej plab hnyuv siab raum lossis hnoos qeev, nrog rau daim nyias nyias ntawm qhov ncauj.

Purpura tshwm sim thaum cov hlab ntsha me tawg, ua rau cov ntshav ntaws rau hauv daim tawv nqaij. Qhov no tuaj yeem tsim cov xim doog rau ntawm daim tawv nqaij uas thaj tsam los ntawm cov me me rau thaj ua rau thaj loj. Purpura pob yog feem ntau benign, tab sis tej zaum yuav qhia qhov kev mob hnyav dua, xws li cov ntshav txhaws.

Qee zaum, cov qib platelet tsawg dua tuaj yeem ua rau txhaws ntshav thiab ntshav ntau dhau. Platelets yog lub qe uas pab koj cov ntshav txhaws. Qes platelet qis qis yuav raug txais los ntawm caj ces los sis caj ces, tab sis lawv kuj tseem cuam tshuam nrog tsis ntev los no:

  • hloov hlwb pob txha
  • mob cancer
  • kev kho tshuaj
  • qog hloov ntshav ntawm tes
  • Cov kab mob HIV
  • kev hloov pauv lawm
  • tshuaj kho estrogen
  • kev siv qee yam tshuaj

Koj yuav tsum hu rau koj tus kws kho mob txhua lub sijhawm yog tias koj pom muaj kev txawv txav lossis hloov ntawm koj cov tawv nqaij.


Cov duab ntawm purpura

Dab tsi ua rau purpura?

Muaj ob hom purpura: nonthrombocytopenic thiab thrombocytopenic. Qhov tsis yog kws lij choj txhais tau hais tias koj muaj cov ntshav qib ib txwm nyob hauv koj cov ntshav. Thrombocytopenic txhais tau tias koj muaj qhov qis dua li cov ntshav plahaum tsis suav.

Cov hauv qab no tuaj yeem ua rau nonthrombocytopenic purpura:

  • kev puas tsuaj uas cuam tshuam ntshav txhaws
  • qee yam mob tsis txaus ntseeg, tshwm sim thaum lossis uantej yug, xws li telangiectasia (tawv nqaij tawv thiab cov tawv nqaij sib kis) lossis Ehlers-Danlos syndrome
  • qee cov tshuaj noj, suav nrog cov tshuaj steroids thiab cov uas cuam tshuam rau lub plawv ua haujlwm
  • cov hlab ntsha tsis muaj zog
  • o hauv cov hlab ntshav
  • scurvy, lossis ua rau tsis muaj cov vitamin C ntau

Cov hauv qab no tuaj yeem ua rau thrombocytopenic purpura:

  • cov tshuaj uas tiv thaiv platelets los ntawm txoj kev los sis uas cuam tshuam nrog kev txhaws
  • cov tshuaj uas ua rau lub cev ua kom muaj kev tiv thaiv tiv thaiv cov ntshav platelets
  • cov ntshav hloov tshiab
  • kev tiv thaiv kab mob xws li idiopathic thrombocytopenic purpura
  • muaj mob rau hauv cov hlab ntshav
  • muaj tus kab mob HIV lossis Kab mob siab C, lossis qee kis mob (Epstein-Barr, rubella, cytomegalovirus)
  • Mob Rocky Mountain pom qhov kub taub hau (los ntawm zuam tom)
  • systemic lupus erythematous

Yuav ua li cas thiaj paub hais tias purpura?

Koj tus kws kho mob yuav tshuaj xyuas koj cov tawv nqaij los kuaj mob purpura. Lawv yuav nug txog koj tsev neeg thiab keeb kwm kev noj qab haus huv ntawm koj tus kheej, xws li thaum pib pom qhov pib me ntsis. Koj tus kws kho mob kuj tseem tuaj kuaj me me rau ntawm daim tawv nqaij ntxiv rau kev sim ntshav thiab ntshav hauv lub cev.


Cov kev sim no yuav pab ntsuas kom paub meej seb puas yog koj purpura puas yog los ntawm kev mob hnyav dua, xws li platelet lossis ntshav tsis txaus. Cov theem ntawm cov platelets tuaj yeem pab qhia qhov ua rau ntawm purpura thiab yuav pab koj tus kws kho mob txiav txim siab txog txoj kev kho mob zoo tshaj plaws.

Purpura tuaj yeem cuam tshuam rau cov menyuam yaus thiab cov laus. Cov menyuam yaus yuav tshwm sim tom qab kis kab mob thiab feem ntau tuaj yeem rov zoo hlo yam tsis muaj kev cuam tshuam. Feem ntau ntawm cov menyuam yaus nrog thrombocytopenic purpura zoo tuaj yeem rov qab los ntawm ntau lub hlis tom qab pib qhov kev tsis zoo. Txawm li cas los xij, hauv cov neeg laus, cov ua rau purpura feem ntau yog mob ntev thiab xav tau kev kho mob los pab tswj cov tsos mob thiab ua kom cov ntshav txhaws nyob hauv qhov tsis muaj mob.

Yuav ua li cas yog purpura kho?

Hom kev kho koj tus kws kho mob yuav hais txog yog vim li cas thiaj ua rau koj purpura. Cov neeg laus thiaj paub tias raug mob thrombocytopenic purpura kuj yuav zoo rov qab yog tsis muaj kev cuam tshuam dab tsi.

Koj yuav tsum tau txais kev kho mob yog tias qhov teeb meem ua rau purpura tsis ploj mus ntawm nws tus kheej. Cov kev kho mob muaj xws li tshuaj kho mob thiab qee zaum kho tus txha caj qaum, lossis phais mob txhawm rau tshem tus po tawm. Tej zaum koj tseem yuav raug hais kom tsis txhob noj tshuaj uas ua rau qhov ua tsis taus plab, xws li tshuaj aspirin, tshuaj ntshav dua, thiab ibuprofen.


Corticosteroids

Koj tus kws kho mob yuav pib koj noj tshuaj corticosteroid, uas tuaj yeem pab ua kom koj cov platelet tsawg dua los ntawm kev ua kom tsawg dua ntawm kev ua haujlwm ntawm koj lub cev. Feem ntau nws yuav siv li ob rau rau lub lis piam rau koj cov platelet kom rov qab mus rau qhov kev nyab xeeb. Thaum nws tsim los, koj tus kws kho mob yuav txiav cov tshuaj.

Nws yog ib qho tseem ceeb uas nrog koj tus kws kho mob tham txog cov kev pheej hmoo ntawm kev noj tshuaj corticosteroids mus sij hawm ntev. Ua li ntawd tuaj yeem ua rau muaj kev mob tshwm sim loj heev, xws li nce phaus, ceeb thawj, thiab pob txha poob.

Tso tshuaj immunoglobulin

Yog tias koj hom purpura ua rau los ntshav heev, koj tus kws kho mob yuav muab cov tshuaj rau koj cov ntshav hu ua intravenous immunoglobulin (IVIG). Lawv kuj tseem tuaj yeem muab rau koj IVIG yog tias koj yuav tsum nce koj cov platelet ntau dua ua ntej kev phais mob. Qhov kev kho no feem ntau muaj txiaj ntsig zoo hauv kev ua kom koj platelet suav, tab sis cov nyhuv feem ntau tsuas yog hauv lub sijhawm luv luv. Nws tuaj yeem ua phiv xws li mob taub hau, xeev siab thiab ua npaws.

Lwm yam tshuaj kho mob

Cov tshuaj kawg siv los kho platelet tsawg rau hauv cov neeg muaj mob tsis muaj zog (idiopathic) thrombocytopenic purpura (ITP) yog romiplostim (Nuj Nplhaib) thiab eltrombopag (Promacta). Cov tshuaj no ua rau cov hlwb pob txha los ua cov platelets ntau, uas txo qhov kev pheej hmoo ntawm nqaij doog thiab los ntshav. Cov teeb meem tshwm sim muaj xws li:

  • mob taub hau
  • kiv taub hau
  • xeev siab
  • mob pob qij txha lossis mob leeg
  • ntuav
  • nce ntawm cov ntshav txhaws
  • tus yam ntxwv mob RAU TXOJ hlab ua pa uas mob ceev
  • cev xeeb tub

Kev siv roj ntsha, xws li tshuaj rituximad (Rituxan), tuaj yeem pab txo lub cev tsis muaj zog tiv thaiv kab mob. Feem ntau nws siv los kho cov neeg mob thiav thiav kabmob ntshav thiav thiab cov neeg mob uas kho corticosteroid tsis zoo. Cov kev mob tshwm sim tuaj yeem suav nrog:

  • ntshav siab
  • mob caj pas
  • ua pob
  • ua npaws

Kev plees kev yi

Yog tias cov tshuaj tsis ua haujlwm zoo rau kev kho thrombocytopenic purpura, koj tus kws kho mob. Kev tshem tawm tus po yog ib txoj kev nrawm ntawm kev ua kom koj cov ntshav platelet. Qhov no yog vim tias tus po pa taws yog lub cev lub luag haujlwm tseem ceeb hauv kev tshem tawm cov platelets.

Txawm li cas los xij, splenectomies tsis tau muaj txiaj ntsig rau txhua tus. Qhov kev phais mob kuj tuaj nrog kev pheej hmoo, xws li txuas ntxiv muaj kev pheej hmoo kis tus mob. Thaum muaj xwm ceev, thaum purpura ua rau los ntshav ntau heev, cov tsev kho mob yuav ua haujlwm hloov ntshav ntawm lub plawv platelet, corticosteroids, thiab immunoglobulin.

Thaum pib kev kho mob, koj tus kws kho mob yuav soj ntsuam koj cov platelet kom pab txiav txim seb nws puas siv tau. Lawv tuaj yeem hloov kho koj txoj kev kho raws li nws ua tau zoo.

Dab tsi yog qhov tshwm sim rau purpura?

Qhov tshwm sim rau purpura yog nyob ntawm qhov mob hauv qab ua rau nws. Thaum koj tus kws kho mob lees tias txoj kev kuaj mob, lawv yuav tham txog cov kev kho thiab qhov yuav pom ntev ntev rau koj tus mob.

Muaj qee zaus, qhov mob thrombocytopenic purpura uas tsis kho kom zoo yuav ua rau tus neeg muaj ntshav tawm hauv qee qhov ntawm lawv lub cev. Kev los ntshav ntau dhau hauv lub hlwb tuaj yeem ua rau ua rau cov ntshav tuag mus rau hauv lub hlwb.

Cov tib neeg uas pib kho tam sim ntawd los yog mob me me feem ntau yuav rov zoo lawm. Txawm li cas los xij, purpura tuaj yeem dhau los ua mob ntev rau thaum mob hnyav lossis thaum kho mob qeeb. Koj yuav tsum ntsib koj tus kws kho mob kom sai li sai tau yog tias koj xav tias koj muaj purpura.

Nyob nrog purpura

Qee lub sij hawm cov pob ntawm purpura tsis ploj tag nrho. Qee yam tshuaj thiab kev ua ub ua no tuaj yeem ua rau cov pob tsuas no tuaj. Txhawm rau txo koj txoj kev pheej hmoo ntawm kev ua cov nqaij pob tshiab lossis ua rau cov pob txha tsis huv, koj yuav tsum zam cov tshuaj uas txo cov ntshav txhaws. Cov tshuaj no suav nrog cov tshuaj aspirin thiab ibuprofen. Koj kuj tseem yuav tsum xaiv cov kev ua haujlwm uas tsis tshua muaj txiaj ntsig los ntawm cov haujlwm siab. Cov kev ua si siab tuaj yeem ua rau koj muaj feem raug mob, doog ntshav, thiab los ntshav.

Nws tuaj yeem nyuaj tiv nrog kev mob tshwm sim ntev. Caw tawm thiab sib tham nrog lwm tus uas muaj kev cuam tshuam yuav pab tau. Mus saib online rau cov pab txhawb nqa uas tuaj yeem txuas koj nrog lwm tus uas muaj purpura.

Q:

Puas muaj tej yam ntuj tso lossis siv tshuaj ntsuab uas muaj txiaj ntsig rau purpura?

Cov neeg tsis qhia npe

A:

Vim tias purpura nthuav dav los ntawm ntau yam ua rau, tsis yog "ib qho loj me rau txhua yam" kev kho mob. Nws yog ib qho tseem ceeb kom paub txog vim li cas tom qab teeb meem. Tam sim no, tsis muaj tshuaj ntsuab los yog tshuaj ntsuab uas tuaj yeem cia siab rau tswj hwm tus mob no.

Yog tias koj xav tshawb txog kev kho mob ntuj tsim lossis lwm txoj kev kho mob rau koj txoj kev noj qab haus huv, nws yog qhov zoo tshaj plaws los sab laj nrog cov kws kho mob sib xyaw. Cov no yog cov kws qhia tshwj xeeb hauv cov kws kho mob hauv tshuaj ntsuab thiab tshuaj ntxiv. Lawv txoj kev tsom xam yog lub hlwb ntawm lub cev uas xav mus kho kom zoo. Koj tuaj yeem nrhiav cov kws paub txog kev noj qab haus huv nyob rau ntawm no: http://integrativemedicine.arizona.edu/alumni.html

Judi Marcin, MDAnswers sawv cev rau kev xav ntawm peb cov kws paub kho mob. Txhua cov ntsiab lus yog cov ntaub ntawv nruj me ntsis thiab yuav tsum tsis txhob txiav txim siab cov lus ntuas kho mob.

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