Xaiv ntawm kev kho mob qog mis qe menyuam

Zoo Siab

• Kev phais mob qog mis hlav
• Kev siv tshuaj kho tus mob khees xaws rau zes qe menyuam
• Rau epithelial ntawm zes qe menyuam mob cancer
• Txog mob kheesxaws ntawm zes qe menyuam pib hauv cov qe menyuam
• Txog ntawm zes qe menyuam mob uas pib hauv stromal hlwb
• Lwm cov txheej txheem tshuaj tua kab mob
• Hluav taws xob rau qog nqaij hlav cancer
• Kev pab kho tus mob cancer rau zes qe menyuam
• Kev kho hom phiaj rau mob zes qe menyuam
• Kev kuaj mob rau neeg mob kheesxaws ntawm zes qe menyuam
• Siv tshuaj los kho kheesxaws ntawm zes qe menyuam
• Outlook

Ua cov phiaj xwm kev kho mob

Muaj ntau ntau txoj hauv kev los mus kho tus mob kheesxaws ntawm zes qe menyuam. Rau feem ntau ntawm cov poj niam, nws txhais tau tias kev phais mob. Qhov no feem ntau ua ke nrog kev kho mob rau tshuaj, kev kho qog noj, lossis hom phiaj kho.

Qee yam uas pab ua kev kho mob yog:

• koj hom tshwj xeeb ntawm zes qe menyuam
• koj theem ntawm kev kuaj mob
• txawm hais tias koj nyob uantej- lossis postmenopausal
• txawm hais tias koj npaj yuav muaj menyuam

Nyeem rau kom paub ntau ntxiv txog kev kho mob cancer ntawm zes qe menyuam thiab seb lawv nkag mus rau.

Kev phais mob qog mis hlav

Cov kev xaiv phais mob nyob ntawm seb koj tus kabmob tau kis mus deb npaum li cas.

Rau cov kabmob ntawm zes qe menyuam thaum ntxov, nws yuav muaj peev xwm khaws cia xeeb tub yug menyuam. Nws yog ib qho tseem ceeb kom sab laj nrog koj tus kws kho mob ua ntej koj yuav phais mob.

Yog tias mob qog tsuas muaj nyob hauv qe menyuam nkaus xwb, koj tus kws kho mob tuaj yeem tshem nws ntxiv thiab tshem lub raj qog uas nws txuas nrog. Koj yuav tau poj niam thiab poj niam yuav poj niam vim tias koj lub zes qe menyuam tseem tshuav, tswj koj txoj kev xaiv kom xeeb tub.

Thaum pom muaj kabmob kheesxaws hauv ob lub zes qe menyuam, koj ob lub zes qe menyuam thiab ob txoj hlab qe menyuam tuaj yeem raug tshem tawm. Qhov no yuav ua rau lawm. Cov tsos mob tuaj yeem suav nrog kub dua, tawm hws hmo ntuj, thiab ua paug ntawm lub paum. Koj tus kws kho mob tseem yuav qhia koj kom tshem koj lub tsev menyuam.

Hauv kev mob kheesxaws ntxov thaum ntxov, kev phais qis laparoscopic tsawg dua tuaj yeem yog ib txoj kev xaiv. Qhov no ua tiav nrog lub koob yees duab vis dis aus thiab ntev, cov twj nyias nyias tso rau hauv cov phais me me.

Yog xav paub ntau dhau ntawm kev mob kheesxaws ntawm zes qe menyuam, yuav tsum tau phais lub plab hauv plab.

Cov txheej txheem hu ua debulking cytoreductive phais yuav siv los kho theem 4 ntawm zes qe menyuam. Nws cuam tshuam txog kev tshem tawm koj cov zes qe menyuam thiab txoj hlab qe menyuam, nrog rau lwm qhov cuam tshuam nrog cov kabmob. Qhov no tuaj yeem suav nrog:

• lub tsev me nyuam thiab ncauj tsev menyuam
• pelvic lymph node
• daim ntaub uas npog koj cov hnyuv thiab cov plab hauv plab
• ib feem ntawm koj daim diaphragm
• plob tsis so tswj
• tus po
• mob siab

Yog tias koj muaj kua dej hauv koj lub plab lossis plab hlaub, nws yuav raug tshem tawm thiab kuaj mob qog nqaij hlav cancer thiab.

Kev siv tshuaj kho tus mob khees xaws rau zes qe menyuam

Kev siv tshuaj zawv plaub hau yog ib hom kev kho mob ib leeg zuj zus. Cov tshuaj haib no taug thoob koj lub cev mus nrhiav thiab rhuav tshem cov qog nqaij hlav cancer. Nws tau siv ua ntej kev phais mob kom qog cov qog los sis tom qab kev phais tua kom tua cov qog nqaij hlav ntxiv.

Cov tshuaj no tuaj yeem muab tshuaj pleev (tshuaj IV) lossis qhov ncauj. Lawv tuaj yeem raug txhaj ncaj qha rau hauv koj lub plab.

Rau epithelial ntawm zes qe menyuam mob cancer

Epithelial ntawm zes qe menyuam mob qog pib hauv hlwb nyob rau sab nraud ntawm koj ob lub zes qe menyuam. Kev kho feem ntau koom nrog tsawg kawg yog ob yam tshuaj IV. Lawv muab sijhawm rau peb txog rau zaug, feem ntau peb mus rau plaub asthiv sib nrug. Tus qauv tshuaj sib xyaw ua ke yog cisplatin lossis carboplatin ntxiv rau paclitaxel (Taxol) lossis docetaxel (Taxotere).

Txog mob kheesxaws ntawm zes qe menyuam pib hauv cov qe menyuam

Qee zaus mob kheesxaws ntawm zes qe menyuam pib hauv koj cov keeb ua haujlwm. Cov no yog cov keeb uas thaum kawg ua rau cov qe. Cov tshuaj sib xyaw ua ke siv rau qog cov hlav ua hlav yog cisplatin (Platinol), etoposide, thiab bleomycin.

Txog ntawm zes qe menyuam mob uas pib hauv stromal hlwb

Kheesxaws ntawm zes qe menyuam kuj tuaj yeem pib mob hlwb stromal. Cov no yog cov cell uas tso cov tshuaj hormones thiab txuas cov nqaij ntawm zes qe menyuam. Cov tshuaj sib xyaw ua ke no zoo li yuav raug siv tib yam rau kev mob qog cov hlav.

Lwm cov txheej txheem tshuaj tua kab mob

Qee yam tshuaj kho rau neeg mob kheesxaws ntawm zes qe menyuam yog:

• albumin-bound paclitaxel (Abraxane)
• altretamine (Hexalen)
• Capecitabine (Xeloda)
• cyclophosphamide (Cytoxan)
• gemcitabine (Gemzar)
• ifosfamide (Ifex)
• Lub tiaj tus (Camptosar)
• liposomal doxorubicin (Doxil)
• melphalan (Alkeran)
• pemetrexed (Alimta)
• topotecan (Hycamtin)
• vinblastine (Velban)
• vinorelbine (Navelbine)

Kev phiv los sis sib txawv nyob ntawm kev siv ntau npaum li cas thiab cov tshuaj sib txuam. Lawv suav nrog:

• xeev siab thiab ntuav
• tsis qab los noj mov
• nkees
• plaub hau poob
• qhov ncauj tawm los yog mob pos hniav los ntshav
• kev pheej hmoo siab ntawm kev kis tus kab mob
• los ntshav lossis doog ntshav

Ntau yam ntawm cov kev mob tshwm sim no tsuas yog ib ntus. Koj tus kws kho mob tuaj yeem pab txo qis. Lwm cov kev phiv, xws li lub raum puas, yuav ua rau mob hnyav dua thiab siv sijhawm ntev. Txawm hais tias koj tseem muaj ib qho ntawm koj lub zes qe menyuam, kev siv tshuaj kho mob tuaj yeem ua rau lub sijhawm pib ntxov.

Hluav taws xob rau qog nqaij hlav cancer

Kev ntsuas hluav taws xob yog lub hom phiaj kev kho mob uas siv hluav taws xob ntau zog los rhuav tshem cov qog. Nws tuaj yeem xa mus rau sab nraud lossis sab hauv.

Hluav taws xob tsis yog thawj txoj kev kho mob kheesxaws ntawm zes qe menyuam. Tab sis nws tuaj yeem siv qee zaum:

• txhawm rau pab kho qhov mob me me, rov tshwm sim hauv cheeb tsam
• kom yooj yim qhov mob los ntawm cov qog loj uas tiv taus tshuaj kho mob
• Ua lwm txoj hauv kev yog tias koj tsis tuaj yeem tiv taus kev siv tshuaj kho

Ua ntej koj thawj qhov kev kho mob, koj yuav tsum muaj kev sib tham los txiav txim siab txog koj li cas. Lub hom phiaj yog tsoo lub qog thaum uas txwv kev puas tsuaj rau cov nqaij mos noj qab haus huv. Pinpoint tattoos yog qee zaum siv los cim koj cov tawv nqaij mus tas li.

Ua tib zoo saib xyuas tau muab tso rau qhov chaw nyob txhua lub sijhawm. Txawm hais tias qhov no tuaj yeem siv sijhawm me ntsis, kev kho tiag tiag tsuas kav ob peb feeb. Hluav taws xob tsis yog mob, tab sis nws yuav tsum ua kom koj nyob twj ywm li qub. Cov kev kho yog muab tsib hnub ib lim tiam rau peb mus rau tsib lub lis piam.

Cov kev mob tshwm sim feem ntau yuav daws thaum kho tas tab sis suav nrog:

• tawv nqaij liab, khaus
• nkees
• zawv plab
• nquag tso zis

Kev pab kho tus mob cancer rau zes qe menyuam

Kev mob kheesxaws Epithelial tsis tshua muaj kev kho nrog tshuaj kho qog. Nws feem ntau siv rau cov mob cancer stromal.

Luteinizing-hormone-tso tawm cov tshuaj hormone agonists yog siv los txo qis cov tshuaj estrogen hauv cov poj niam premenopausal. Ob ntawm cov no yog goserelin (Zoladex) thiab leuprolide (Lupron). Lawv tau muab los ntawm kev txhaj tshuaj txhua ib mus rau peb hlis. Cov tshuaj no tuaj yeem ua rau lub cev ntas. Yog tias noj rau xyoo, lawv tuaj yeem ua rau koj cov pob txha tsis muaj zog thiab ua kom pob txha.

Estrogen tuaj yeem txhawb nqa qog noj hlav. Ib cov tshuaj hu ua tamoxifen ua rau cov tshuaj estrogen los ntawm kev ua kom muaj kev loj hlob. Cov tshuaj no kuj tseem tuaj yeem ua rau muaj lub cev ntas.

Cov poj niam uas tau postmenopausal tuaj yeem siv tshuaj aromatase inhibitors, xws li anastrozole (Arimidex), zam kis (Aromasin), thiab letrozole (Femara). Lawv thaiv cov enzyme uas hloov lwm cov tshuaj hormones rau hauv estrogen. Cov tshuaj noj ntawm qhov ncauj tau noj ib hnub ib zaug. Cov kev phiv nrog:

• kub muag kawg
• txha thiab cov leeg mob
• thinning ntawm koj cov pob txha

Kev kho hom phiaj rau mob zes qe menyuam

Cov tshuaj tseem ceeb nrhiav thiab hloov pauv qee yam kev mob hlwb uas tsis pom muaj nyob hauv cov qe ntshav zoo. Lawv ua tsawg dua kev puas tsuaj rau cov nqaij noj qab haus huv zoo dua li kev siv tshuaj kho mob lossis kev kho hluav taws xob sab nraud.

Cov qog xav tau cov hlab ntsha kom loj tuaj thiab kis tau. Qhov tshuaj IV hu ua bevacizumab (Avastin) yog tsim los txwv qog los ntawm txoj kev tsim cov ntshav tshiab. Nws muab txhua ob rau peb asthiv.

Cov kev tshawb fawb qhia tias bevacizumab tuaj yeem ua rau qog qog lossis qeeb epithelial ntawm zes qe menyuam mob zuj zus. Cov teeb meem tshwm sim muaj xws li:

• ntshav siab
• cov qe ntshav dawb tsawg
• zawv plab

Poly (ADP-ribose) polymerase (PARP) inhibitors yog qhov ncauj noj tshuaj. Lawv tau siv thaum muaj kev mob kheesxaws ntawm zes qe menyuam BRCA hloov pauv noob.

Ob ntawm cov no, olaparib (Lynparza) thiab rucaparib (Rubraca), tuaj yeem siv rau mob qog qe menyuam tom qab-theem tom qab sim tshuaj kho mob. Olaparib tseem tseem siv coj los kho mob kheesxaws ntawm zes qe menyuam rau cov poj niam uas muaj lossis tsis muaj BRCA kev sib faib.

Lwm qhov PARP inhibitor, niraparib (Zejula), tuaj yeem muab rau cov poj niam uas muaj kabmob kheesxaws zes qe menyuam, nrog lossis tsis BRCA kev sib hloov, tom qab sim kev siv tshuaj lom neeg.

Cov kev mob tshwm sim los ntawm cov tshuaj no tuaj yeem suav nrog:

• xeev siab
• anemia
• leeg thiab leeg mob

Kev kuaj mob rau neeg mob kheesxaws ntawm zes qe menyuam

Cov chaw kuaj mob sib piv cov qauv kev kho mob nrog cov kev kho tshiab tshiab tseem tsis tau pom zoo rau kev siv dav dav. Soj ntsuam kev kuaj mob tuaj yeem koom nrog cov tib neeg muaj theem mob cancer.

Nug koj tus kws kho mob seb puas muaj kev sim kho mob zoo rau koj. Koj tseem tuaj yeem mus saib tau hauv cov ntawv tshawb fawb hauv ClinicalTrials.gov yog xav paub ntau ntxiv.

Siv tshuaj los kho kheesxaws ntawm zes qe menyuam

Koj yuav pom tau tias nws muaj txiaj ntsig zoo los pab kho koj tus mob qog nqaij hlav nrog kev kho kom zoo. Qee tus neeg pom tias lawv nce lub neej zoo. Qee qhov koj yuav xav txog yog:

• Tshuaj tsw qab. Tseem ceeb roj yuav txhim kho koj lub siab thiab txo kev ntxhov siab.
• Kev xav. Cov hau kev so rau cov neeg tuaj yeem pab txo qhov mob thiab txhim kho pw tsaug zog.
• Kev zaws kho. Qhov kev kho mob zoo li no rau koj lub cev yuav pab txo qis kev ntxhov siab thiab txo kev ntxhov siab thiab mob.
• Tai chi thiab yoga. Nonaerobic lub cev-kev coj ua uas siv lub zog, ua kom zoo, thiab ua pa tuaj yeem txhawb koj txoj kev paub zoo.
• Txoj kev kho kom zoo nkauj thiab kho nkauj. Kev tawm tswv yim tawm tuaj yeem pab koj daws nrog txoj kev xav ntawm mob cancer thiab kho mob.
• Kev Siv Tshuaj Tua Tsiaj. Daim foos ntawm cov tshuaj Suav no hauv cov koob uas cov phiaj xwm tso tawm tau tuaj yeem daws qhov mob thiab lwm cov tsos mob.

Tshawb xyuas koj tus kws kho mob ua ntej sim cov kev kho mob tshiab, tshwj xeeb yog kev noj zaub mov noj lossis tshuaj ntsuab ntxiv. Cov no tuaj yeem cuam tshuam nrog koj cov tshuaj noj lossis ua lwm yam teeb meem.

Koj kuj yuav xav sab laj nrog tus kws kho mob palliative care. Cov kws kho mob no ua haujlwm nrog koj pab neeg oncology los pab cov kev mob tshwm sim thiab txhim kho lub neej kom zoo.

Outlook

Zuag qhia tag nrho cov neeg txheeb ze muaj txoj sia ntawm tus mob cancer ntawm zes qe menyuam yog 45 feem pua.

Ciaj sia taus cov nqi sib txawv raws li hom mob cancer, theem ntawm kev kuaj mob, thiab hnub nyoog. Piv txwv li, thaum muaj mob qog noj ua ntej nws yuav kis tau sab nraum koj lub zes qe menyuam, qhov muaj txoj sia nyob yog 92 feem pua.

Tsis tas li, cov ntaub ntawv teev kev ciaj sia tsis suav nrog cov xwm txheej tsis ntev dhau los no, thaum cov kev kho tshiab tau siv.

Koj tus kws kho mob yuav muab ib lub tswv yim rau koj yam uas yuav muaj kev cia siab raws li qhov tshwj xeeb ntawm koj hom phiaj xwm kuaj mob thiab kho mob.