Lactic Acidosis: Yam Uas Koj Yuav Tsum Tau Paub

Zoo Siab

• Cov tsos mob zoo li cas?
• Dab tsi ua?
• Kab mob plawv
• Kev kis mob hnyav (sepsis)
• HIV
• Mob Cancer
• Mob plob tsis so tswj (plab me ntsis)
• Kev siv tshuaj Acetaminophen
• Kev haus cawv mus ntev
• Kev siv dag zog lossis ua haujlwm lub cev
• Lactic acidosis thiab ntshav qab zib
• Nws kuaj tau li cas?
• Cov kev kho mob yog dab tsi?
• Qhov tshwm sim yog dab tsi?
• Tiv thaiv cov kab mob lactic acidosis

Lactic acidosis yog dab tsi?

Cov kab mob lactic acidosis yog ib hom kev mob metabolic acidosis uas pib thaum ib tug neeg ua haujlwm dhau los yog underutilizes lactic acid, thiab lawv lub cev tsis tuaj yeem hloov kho rau cov kev hloov no.

Cov neeg muaj mob lactic acidosis muaj (thiab qee zaum lawv lub raum) muaj peev xwm tshem tawm cov acid ntau ntawm lawv lub cev. Yog tias cov kab mob lactic tsim ntau ntxiv hauv lub cev sai dua qhov nws yuav raug tshem tawm, acidity hauv lub cev hauv lub cev - xws li ntshav - nce siab.

Qhov no tsim ntawm cov kua qaub ua rau lub cev tsis txaus ntawm qib pH ntawm lub cev, uas ib txwm yuav tsum yog me ntsis alkaline es tsis txhob acidic. Muaj ob peb yam sib txawv ntawm cov acidosis.

Lactic acid buildup tshwm sim thaum tsis muaj oxygen txaus hauv cov leeg nqaij kom zom cov piam thaj thiab glycogen. Qhov no hu ua anaerobic metabolism.

Muaj ob hom lactic acid: L-lactate thiab D-lactate. Feem ntau hom mob lactic acidosis tshwm sim los ntawm cov L-lactate ntau dhau.

Muaj ob hom lactic acidosis, Hom A thiab Hom B:

• Hom A lactic acidosis yog tshwm sim los ntawm cov nqaij mos hypoperfusion tshwm sim los ntawm hypovolemia, mob plawv tsis ua haujlwm, sepsis, lossis cardiopulmonary ntes.
• Hom B lactic acidosis yog tshwm sim los ntawm kev tsis taus ntawm lub cev kev ua haujlwm thiab thaj chaw hauv cheeb tsam ntawm cov nqaij mos hypoperfusion.

Lactic acidosis muaj ntau yam ua rau thiab tuaj yeem kho tau ntau zaus. Tab sis yog tias tsis kho, nws yuav muaj kev phom sij.

Cov tsos mob zoo li cas?

Cov tsos mob ntawm tus kab mob lactic acidosis yog ib txwm muaj ntawm ntau yam teeb meem kev noj qab haus huv. Yog koj muaj cov tsos mob no, koj yuav tsum hu koj tus kws kho mob sai. Koj tus kws kho mob tuaj yeem pab txiav txim siab lub hauv paus.

Muaj ntau cov tsos mob ntawm tus kab mob lactic acid sawv cev rau kev mob xwm txheej ceev:

• hawb pob ua pa tsw phem (qhov qhia tau tias qhov cuam tshuam hnyav ntawm ntshav qab zib, hu ua ketoacidosis)
• tsis meej pem
• daj ntseg (daj tawv nqaij lossis ntsiab muag dawb)
• teeb meem ua pa lossis ntiav, ua pa ceev

Yog koj paub los yog xav tias koj muaj cov kab mob lactic acidosis thiab muaj cov tsos mob no, hu rau 911 lossis mus rau chav kho mob ceev tam sim.

Lwm cov tsos mob lactic acidosis suav nrog:

• sab sab lossis qaug zog heev
• mob leeg los yog mob
• lub cev tsis muaj zog
• Tag nrho cov kev xav ntawm lub cev tsis xis nyob
• mob plab los yog tsis xis nyob
• zawv plab
• txo hauv qab los noj mov
• mob taub hau
• lub plawv dhia ceev ceev

Dab tsi ua?

Cov kab mob lactic acidosis muaj ntau lub hauv paus hauv ntsis, nrog rau cov pa roj carbon monoxide lom, tus mob raws plab, mob npaws, thiab asphyxiation. Qee qhov laj thawj suav nrog:

Kab mob plawv

Tej yam mob xws li raug lub plawv dhia thiab lub plawv tsis ua haujlwm yuav txo tau cov ntshav thiab oxygen mus thoob plaws lub cev. Qhov no tuaj yeem nce qib lactic acid ntau.

Kev kis mob hnyav (sepsis)

Txhua yam kev kis mob hnyav lossis kab mob tuaj yeem ua rau mob sepsis. Cov neeg muaj tus mob sepsis yuav muaj qhov chob ntau hauv cov kab mob lactic acid, tshwm sim los ntawm cov pa oxygen tsawg.

HIV

Cov tshuaj tiv thaiv kab mob HIV, xws li nucleoside rov qab transcriptase inhibitors, tuaj yeem tsim cov qib lactic acid. Lawv kuj yuav ua rau lub siab puas. Qhov no ua rau nws nyuaj rau lub cev ua cov txheej txheem lactate.

Mob Cancer

Cov kabmob hlwb tsim cov lactic acid. Qhov no buildup ntawm lactic acid tej zaum yuav nrawm raws li ib tug neeg poob phaus thiab tus mob zuj zus.

Mob plob tsis so tswj (plab me ntsis)

Thaum lub sijhawm, cov neeg uas lub plab luv luv tuaj yeem pom cov D-lactic acid tsim, los ntawm cov kab mob overgrowth hauv plab hnyuv me. Cov tib neeg uas twb muaj lub plab phais yuav tau tus mob D-lactic acidosis.

Kev siv tshuaj Acetaminophen

Nquag siv tsis tu ncua ntawm kev siv tshuaj acetaminophen (Tylenol) tuaj yeem ua rau lactic acidosis, txawm tias noj thaum siv tshuaj yog. Qhov no yog vim nws tuaj yeem ua rau muaj kev txuam nrog pyroglutamic acid nyob rau hauv cov ntshav.

Kev haus cawv mus ntev

Kev haus dej haus cawv ntau dhau mus ib ncua sij hawm tuaj yeem ua rau lactic acidosis thiab ketoacidosis dej cawv. Cetoacidosis yuav yog ib qho muaj peev xwm ua rau tuag taus yog tias tsis kho, tab sis nws tuaj yeem txuas nrog kev nqus dej (IV) hydration thiab qabzib.

Kev haus dej cawv nce qib phosphate, uas ua rau tsis zoo hauv lub raum. Qhov no ua rau lub cev pH ntau cov kua qaub. Yog koj muaj teeb meem txo kev haus dej haus cawv kom tsawg, pawg txhawb yuav pab tau.

Kev siv dag zog lossis ua haujlwm lub cev

Kev tsim cov lactic acid uas nyob ib ntus tuaj yeem tshwm sim los ntawm kev tawm dag zog yog tias koj lub cev tsis muaj oxygen txaus ua kom cov piam thaj hauv cov ntshav tawm mus. Qhov no tuaj yeem ua rau txoj kev xav hauv cov pawg leeg uas koj siv. Nws kuj tseem tuaj yeem ua rau xeev siab thiab tsis muaj zog.

Lactic acidosis thiab ntshav qab zib

Ib qho kev kawm tshwj xeeb ntawm cov tshuaj tiv thaiv ntshav qab zib hauv qhov ncauj, hu ua biguanides, tuaj yeem ua rau cov lactic acid qib tsim nyog.

Metformin (Glucophage) yog ib qho ntawm cov tshuaj no. Nws tau siv los kho mob ntshav qab zib thiab tseem yuav raug tshuaj rau lwm yam mob, xws li mob raum tsis txaus. Metformin tseem tseem siv tawm cov ntawv cim los kho tus mob polycystic ovarian syndrome.

Hauv cov neeg muaj ntshav qab zib, mob lactic acidosis yuav muaj kev txhawj xeeb ntau yog tias muaj mob raum. Yog tias koj muaj ntshav qab zib thiab muaj cov tsos mob ntawm tus kab mob lactic acid, hu rau 911 lossis mus rau chav kub ntxhov sai.

Nws kuaj tau li cas?

Lactic acidosis tau kuaj pom los ntawm kev soj ntsuam ntshav sai. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj lossis haus dab tsi rau 8 rau 10 teev ua ntej ntsuas. Koj tseem yuav raug qhia kom tswj koj theem kev ua hauv cov xuaj moos ua ntej mus rau qhov kev ntsuas.

Thaum qhov kev kuaj ntawd, koj tus kws kho mob yuav qhia koj kom tsis txhob txhaws koj lub nrig, vim tias qhov no yuav tso ntau qib kua qaub. Kev khi txoj hlua khi ncig ntawm caj npab kuj tseem yuav muaj qhov tshwm sim no.

Rau cov laj thawj no, lactic acidosis ntshav kuaj qee zaum ua los ntawm kev pom txoj hlab ntshav nyob sab nraub qaum txhais tes es tsis txhob caj npab.

Cov kev kho mob yog dab tsi?

Txoj kev zoo tshaj los kho cov mob lactic acidosis yog los ntawm kev kho nws lub hauv paus cag. Vim li ntawd, kev kho mob sib txawv.

Lactic acidosis qee zaum sawv cev rau kev mob xwm txheej kub. Qhov no yuav tsum tau kho cov tsos mob, tsis hais lawv lub hauv paus. Ua kom cov pa mus rau cov ntaub so ntswg thiab muab cov dej ua kua dej IV ntau zaus yog siv los txo cov qib kua qaub qis.

Lactic acidosis tshwm sim los ntawm kev qoj ib ce tuaj yeem kho tom tsev. Tiv thaiv yam koj ua kom hydrate thiab so kom txaus, feem ntau pab. Electrolyte-hloov cov kis las haus dej, xws li Gatorade, pab nrog hydration, tab sis dej feem ntau zoo tshaj plaws.

Qhov tshwm sim yog dab tsi?

Raws li lub hauv paus pib, kev kho mob rau cov kab mob lactic acid feem ntau ua rau tag nrho cov kev rov qab los, tshwj xeeb yog tias kev kho mob sai. Qee zaum, lub raum tsis ua haujlwm lossis ua pa tsis ua haujlwm tuaj yeem ua tau. Thaum tsis kho, cov kab mob lactic acidosis tuaj yeem ua rau neeg tuag taus.

Tiv thaiv cov kab mob lactic acidosis

Lactic acidosis tiv thaiv kuj tau txiav txim siab los ntawm nws lub peev xwm ua tau. Yog tias koj muaj ntshav qab zib, HIV, lossis mob qog noj ntshav, tham txog koj tus mob thiab cov tshuaj uas koj xav tau nrog koj tus kws kho mob.

Cov kab mob lactic acid los ntawm kev tawm dag zog tuaj yeem tiv thaiv tau los ntawm kev dej kom tsis muaj dej thiab muab sijhawm rau koj tus kheej kom ntev so ntawm kev tawm dag zog.

Nws tseem ceeb heev kom tsis txhob haus dej cawv tsis txaus. Tham txog kev kho kom rov zoo thiab 12-qib kev xaiv nrog koj tus kws kho mob lossis kws sab laj.