Kev tiv thaiv kab mob hauv lub cev rau Crohn's Kab Mob

Zoo Siab

• Azathioprine
• Mercaptopurine
• Methotrexate
• Yam uas yuav tau khaws rau hauv siab

Txheej txheem cej luam

Tsis muaj txoj hau kev los kho tus mob Crohn's, yog li kev mob tshwm sim los ntawm kev kho kom zoo. Muaj ntau txoj kev kho mob rau koj uas tuaj yeem pab txo koj cov tsos mob. Immunomodulators yog tshuaj uas hloov kho lub cev tiv thaiv kab mob.

Rau ib tus neeg muaj Crohn's, qhov no tuaj yeem pab txo qhov o uas ua rau ntau cov tsos mob.

Cov tshuaj tiv thaiv kab mob suav nrog cov tshuaj uas yog cov tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob. Cov tshuaj tiv thaiv kab mob ua rau lub cev tiv thaiv kab mob, tab sis kev tiv thaiv kab mob hauv lub cev tseem tuaj yeem ua rau lub cev tsis zoo rau lwm cov kab mob.

Cov tshuaj tiv thaiv kab mob ntau ntxiv lossis "txhawb" lub cev tiv thaiv kab mob ntawm lub cev, uas ua rau lub cev pib sib ntaus mob.

Muaj ntau yam tshuaj tiv thaiv kab mob, txhua tus muag hauv nws cov khoom lag luam muaj npe. Azathioprine, mercaptopurine, thiab methotrexate yog peb hom loj.

Azathioprine

Azathioprine feem ntau siv rau cov neeg tau txais kev hloov khoom nruab nrog cev kom tiv thaiv lub cev tsis kam lees lub cev tshiab los ntawm kev tawm tsam lub cev tiv thaiv kab mob. Nws kuj tseem siv los kho kev mob caj dab, uas yog ib qho mob uas tus neeg lub cev tawm tsam lawv cov pob qij txha.

Txawm hais tias azathioprine tsis tau pom tias muaj txiaj ntsig zoo rau kev txo qis Crohn cov tsos mob los yog ua tiav kev zam txim, nws yuav txo qhov kev xav tau kev kho mob steroid. Kev tshawb fawb qhia tau tias azathioprine pab ua rau tib neeg nyob rau hauv kev zam txim thaum Crohn cov tsos mob tau tswj.

Vim li no, American College of Gastroenterology txhawb nqa siv azathioprine rau cov neeg uas muaj kev zam txim lossis tseem muaj cov tsos mob txawm tias siv tshuaj steroids.

Kuj tseem muaj qee qhov tsis tshua pom muaj, tab sis hnyav, phiv ntawm azathioprine. Cov tshuaj no ua rau koj lub cev tsim cov qe ntshav dawb tsawg dua. Qhov no tuaj yeem tsim teebmeem vim tias cov qe ntshav dawb tua cov kabmob sib kis.

Cov tib neeg noj azathioprine kuj tseem tuaj yeem ua rau mob nqaij hlav lossis mob ntshav thiav ntau dua.

Vim tias cov kev mob tshwm sim no, azathioprine feem ntau tsuas yog kho rau mob hnyav rau mob hnyav mus rau Crohn's. Koj yuav tsum xav txog txhua yam kev pheej hmoo ua ntej noj azathioprine. Koj tseem yuav raug sim rau TPMT tsis muaj peev xwm, uas tuaj yeem cuam tshuam rau koj lub cev.

Mercaptopurine

Mercaptopurine, tseem hu ua 6-MP, yog paub kom txwv tsis pub muaj mob qog noj ntshav. Cov tshuaj no feem ntau siv rau kev kho mob qog ntshav. Hauv cov neeg muaj Crohn's, mercaptopurine tuaj yeem pab tswj kev so kom txaus.

Mercaptopurine tuaj yeem txo cov qe ntshav dawb thiab ntshav liab ntau ntau. Koj tus kws kho mob yuav xav ua qhov kev ntsuam xyuas ntshav tas li kom paub tseeb tias tsis muaj kev puas tsuaj rau koj cov pob txha pob txha. Koj tseem yuav raug sim rau TPMT tsis muaj peev xwm, uas tuaj yeem cuam tshuam rau koj lub cev.

Lwm yam kev phiv los ntawm mercaptopurine tuaj yeem suav nrog:

• qhov ncauj tawm
• ua npaws
• mob caj pas
• cov ntshav nyob hauv cov zis lossis cov quav

Koj yuav tsum xav txog tag nrho cov kev phiv ua ntej koj pib kho.

Methotrexate

Methotrexate thaiv cov metabolism hauv cell, uas ua rau lub hlwb tuag. Qhov no tau ua rau nws siv rau Crohn tus kabmob, mob qog noj ntshav, thiab mob psoriasis.

American College of Gastroenterology txhawb nqa siv methotrexate los kho cov tsos mob ntawm Crohn's mob rau cov neeg uas vam khom cov tshuaj steroids. Methotrexate kuj tseem pab kom cov neeg nrog Crohn's hauv kev zam txim.

Txawm li cas los xij, methotrexate muaj cov kev mob tshwm sim uas suav nrog kev tuaj yeem ua rau lub siab lossis mob pob txha thiab, muaj qee zaus, mob toxicity ntawm lub ntsws. Tus txiv neej lossis tus poj niam uas sim xeeb tub yuav tsum tsis txhob siv cov tshuaj no. Cov kev mob tshwm sim tsawg dua muaj xws li:

• mob taub hau
• tsaug zog
• daim tawv nqaij ua pob
• xeev siab thiab ntuav
• plaub hau poob

Yam uas yuav tau khaws rau hauv siab

Cov tshuaj tiv thaiv kab mob tuaj yeem pab tua cov tsos mob ntsig txog Crohn's kab mob, tab sis lawv cuam tshuam nrog koj lub cev lub peev xwm los tua kab mob sib kis. Thaum siv tshuaj tiv thaiv kab mob rau lub cev, mloog zoo rau tej cim qhia txog tus kab mob, xws li ua npaws lossis ua daus no.

Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob tam sim ntawd.

Txhua lub sijhawm koj noj tshuaj immunomodulators, nco ntsoov koj tus kws kho mob ntsuas koj cov ntshav tsis tu ncua rau cov cim qhia txog kev puas tsuaj rau koj cov pob txha thiab cov khoom hauv nruab nrog cev.

Qee cov neeg siv tshuaj tiv thaiv kab mob tej zaum yuav zoo rau noj thaum cev xeeb tub, tab sis koj yuav tsum tham txog qhov zoo thiab qhov zoo ntawm kev pib siv tshuaj tshiab nrog koj tus kws kho mob ua ntej. Koj yuav tsum tham nrog koj tus kws kho mob yog tias koj cev xeeb tub lossis, txawm tias koj yog tus txiv neej lossis poj niam, tej zaum yuav xeeb tub.