Histiocytosis: nws yog dab tsi, cov tsos mob thiab kev kho mob

Zoo Siab

• Cov tsos mob tseem ceeb
• Yuav kuaj li cas
• Yuav kho li cas

Histiocytosis sib raug rau ib pawg kab mob uas tuaj yeem tsim los ntawm kev tsim khoom ntau thiab muaj cov histiocytes ncig hauv cov ntshav, uas, txawm hais tias tsis tshua muaj, ntau zaus rau cov txiv neej thiab nws txoj kev kuaj mob tau tsim nyob rau thawj xyoo ntawm lub neej, txawm tias muaj cov cim qhia tus kab mob kuj tuaj yeem tshwm sim tau thaum muaj hnub nyoog li cas.

Histiocytes yog cov hlwb muab tau los ntawm monocytes, uas yog lub hlwb rau lub cev tiv thaiv kab mob, thiab yog li lub luag haujlwm rau kev tiv thaiv kab mob ntawm lub cev. Tom qab ua haujlwm txheej txheem ntawm kev sib txawv thiab paub tab, lub monocytes tau paub hu ua macrophages, uas tau muab lub npe tshwj xeeb raws li qhov chaw uas lawv tshwm sim hauv lub cev, raug hu ua Langerhans hlwb thaum pom nyob rau hauv epidermis.

Txawm hais tias histiocytosis cuam tshuam ntau dua rau kev hloov pauv ntawm kev ua pa, histiocytes tuaj yeem tsim nyob hauv lwm qhov chaw hauv lub cev, xws li tawv nqaij, pob txha, mob siab thiab cov leeg hlwb, uas ua rau muaj cov tsos mob sib txawv raws li qhov chaw nyob ntawm qhov loj tshaj ntawm histiocytes.

Cov tsos mob tseem ceeb

Histiocytosis tuaj yeem yog asymptomatic lossis kev nce qib mus rau qhov pib ntawm cov tsos mob sai. Cov tsos mob thiab cov tsos mob uas qhia txog cov mob histiocytosis yuav txawv raws qhov chaw uas muaj cov mob histiocytes ntau dua. Yog li, cov tsos mob tseem ceeb yog:

• Hnoos;
• Ua npaws;
• Lub cev hnyav tuaj yam tsis pom tseeb;
• Ua pa nyuaj;
• Nkees dhau heev;
• Kev Mob Hlav;
• Muaj feem ntau dua ntawm kev kis tus kab mob;
• Cov teeb meem coagulation;
• Cov tawv nqaij ua pob;
• Mob plab;
• Kev nrawm nrawm;
• Ncua kev nkauj nraug tos qhua;
• Kiv taub hau.

Cov keeb kwm loj ntawm cov tshuaj histiocytes tuaj yeem ua rau ntau dhau ntawm cytokines, ua rau cov txheej txheem ua mob thiab txhawb cov qog, ntxiv rau qhov ua rau kev puas tsuaj rau cov kabmob uas cov tsub zuj zuj ntawm cov hlwb no tau txheeb xyuas qhov tseeb. Nws nquag dua rau cov keeb kwm mob cuam tshuam rau pob txha, tawv nqaij, nplooj siab thiab mob ntsws, tshwj xeeb yog muaj keeb kwm ntawm kev haus luam yeeb. Tsawg tsawg zaus, cov mob histiocytosis tuaj yeem cuam tshuam txog ntawm cov hlab ntsha hauv nruab nrab, cov qog ntshav, lub plab thiab lub qog.

Vim tias qhov tseeb ntawm cov menyuam yaus lub cev tsis muaj zog tiv thaiv kab mob tsis zoo, nws muaj peev xwm ua rau ntau lub plab hnyuv siab raum yuav raug cuam tshuam yooj yim dua, uas ua rau kev paub ntxov thiab pib kho sai sai.

Yuav kuaj li cas

Kev txheeb xyuas tus kab mob histiocytosis feem ntau yog ua los ntawm kev kuaj me me ntawm qhov chaw cuam tshuam, qhov twg nws tuaj yeem soj ntsuam los ntawm kev kuaj tsom hauv lub tshuab tsom, lub xub ntiag ntawm qhov infiltrate nrog kev nthuav dav ntawm histiocytes hauv cov nqaij uas yav dhau los noj qab haus huv.

Tsis tas li ntawd, lwm qhov kev ntsuam xyuas kom paub meej txog kev kuaj mob, xws li suav tomography, kev tshawb fawb rau kev hloov pauv cuam tshuam nrog tus kabmob no, xws li BRAF, piv txwv, ntxiv rau kev tshuaj tiv thaiv kab mob ntshav thiab kuaj ntshav, nyob rau hauv uas tej zaum yuav muaj kev hloov pauv ntawm tus nqi neutrophils , lymphocytes thiab eosinophils.

Yuav kho li cas

Kev kho mob ntawm histiocytosis nyob ntawm thaj tsam ntawm tus kab mob thiab thaj chaw muaj kev cuam tshuam, thiab kev siv tshuaj kho mob, kev kho duab hluav taws xob, kev siv tshuaj tiv thaiv kab mob los yog kev phais mob raug pom zoo, tshwj xeeb tshaj yog muaj cov pob txha koom nrog. Thaum cov histiocytosis tshwm sim los ntawm kev haus luam yeeb, piv txwv li, kev txiav luam yeeb yog kev pom zoo, txhim kho tus neeg mob tus mob.

Feem ntau, qhov mob yuav kho tau ntawm nws tus kheej lossis ploj vim kev kho mob, txawm li cas los nws tuaj yeem rov tshwm sim dua. Yog li, nws yog ib qho tseem ceeb uas tus neeg yuav tsum tau soj qab saib xyuas tas li kom kws kho mob tuaj yeem soj ntsuam tau yog tias muaj kev pheej hmoo ntawm kev txhim kho tus kab mob thiab, yog li, tsim kev kho mob thaum ntxov.