Congenital hypothyroidism yog dab tsi, mob tshwm sim thiab yuav kho li cas

Zoo Siab

• Cov tsos mob ntawm tus mob Congenital hypothyroidism
• Yuav kuaj li cas
• Cov tseem ceeb ua
• Txoj kev kho rau tus kab mob Congenital hypothyroidism

Congenital hypothyroidism yog qhov teeb meem metabolic uas cov menyuam cov thyroid tsis tuaj yeem tsim cov thyroid hormones txaus, T3 thiab T4, uas tuaj yeem cuam tshuam tus menyuam txoj kev loj hlob thiab ua rau cov leeg muaj kev hloov pauv mus ib txhis yog tias tsis txheeb xyuas thiab kho tau.

Kev kuaj mob ntawm tus kab mob hlav ntshav qab zib (Congenital hypothyroidism) yog tsim nyob rau hauv chav tsev menyuam thiab, yog tias pom muaj cov pauv hloov nyob rau hauv cov thyroid, kev kho yog pib sai sai tom qab dhau los ntawm kev hloov tshuaj hormone kom tsis txhob muaj teeb meem rau tus menyuam. Congenital hypothyroidism tsis muaj kev kho tau, tab sis thaum kev kuaj mob thiab kev kho mob tau ua thaum ntxov, tus menyuam muaj peev xwm txhim kho feem ntau.

Cov tsos mob ntawm tus mob Congenital hypothyroidism

Cov tsos mob ntawm tus mob Congenital hypothyroidism cuam tshuam txog qib qis ntawm T3 thiab T4 ncig mus ncig hauv tus menyuam lub cev, tuaj yeem pom:

• Nqaij hypotonia, uas sib raug rau cov leeg nqaij flaccid;
• Nce ntim ntawm tus nplaig;
• Cov hlwv ntxau;
• Kho pob txha txhim kho;
• Ua tsis taus pa nyuaj;
• Bradycardia, uas sib raug rau lub plawv dhia qeeb kawg;
• Kev Mob Hlav;
• Txaus ntshai dhau;
• Kev nyuaj hauv kev pub mis;
• Ncua nyob rau hauv kev tsim ntawm thawj zaug kev kho hniav;
• Qhuav ntawm daim tawv nqaij nrog tsis muaj elasticity;
• Hlwb ruam;
• Ncua hauv kev loj hlob neuronal thiab psychomotor.

Txawm hais tias muaj cov tsos mob tshwm sim, tsuas yog kwv yees li 10% ntawm cov menyuam yaus uas mob los ntawm kev mob ntsws yug los ua haujlwm muaj lawv, vim hais tias kev kuaj mob tau ua nyob hauv niam tsev menyuam thiab kev hloov kho tshuaj yog pib sai tom qab, tiv thaiv qhov pib ntawm cov tsos mob.

Yuav kuaj li cas

Kev kuaj mob ntawm tus kab mob ntshav siab lub ntsws yug menyuam yog tsim thaum lub sijhawm menyuam yug menyuam hauv qhov kev kuaj menyuam, feem ntau yog ntsuas tus menyuam lub plab, hauv qee ob peb tee ntshav tau los ntawm tus menyuam lub pob taws thiab xa mus rau qhov chaw kuaj. Saib ntxiv txog kev ntsuas prick pob taws.

Yog hais tias kev ntsuas pob taws pom tias yog tus kab mob siab ntsws (Congenital hypothyroidism), kev ntsuas ntawm cov tshuaj hormones T4 thiab TSH yuav tsum tau ua los ntawm kev kuaj ntshav rau kev kuaj mob kom paub meej thiab pib kho. Lwm yam kev kuaj mob xws li ultrasound, MRI thiab thyroid scintigraphy, kuj tseem siv tau hauv kev kuaj mob.

Cov tseem ceeb ua

Congenital hypothyroidism tuaj yeem tshwm sim los ntawm ntau lub sijhawm, lub ntsiab yog:

• Txoj kev tsis tsim los ua tsis tiav los ua cov thyroid caj pas;
• Kev tsim nyob rau hauv ib qho chaw tsis xwm yeem ntawm cov thyroid caj pas;
• Kev ua tsis zoo hauv lub synthesis ntawm cov thyroid hormones;
• Cov nqaij nyob hauv lub qhov txhab lossis hypothalamus, uas yog ob lub qog hauv lub hlwb ua lub luag haujlwm rau kev tsim khoom thiab kev cai hauv cov tshuaj hormones.

Feem ntau, cov mob Congenital hypothyroidism yog tas mus li, txawm li cas los xij, cov kab mob qog nqaij hlav Congenital hypothyroidism tuaj yeem tshwm sim, uas tuaj yeem tshwm sim los ntawm qhov tsis txaus los yog tshaj iodine los ntawm leej niam lossis tus menyuam yug tshiab lossis los ntawm kev tso tawm los ntawm cov placenta ntawm antithyroid tshuaj.

Hloov ntshav ntawm lub sijhawm thaum yug menyuam tseem yuav tau muaj kev kho mob, tab sis nws ib txwm tso tseg thaum muaj 3 xyoo, yog li kev ntsuam xyuas tuaj yeem coj los ntsuas cov theem ntawm cov ntshav ncig cov thyroid thiab li tias hom thiab ua rau tus kabmob tuaj yeem txhais tau zoo dua.

Txoj kev kho rau tus kab mob Congenital hypothyroidism

Kev kho kab mob siab ntsws Congenital hypothyroidism muaj kev hloov pauv ntawm cov thyroid cov tshuaj hormones thoob lub neej los ntawm kev siv tshuaj, Levothyroxine sodium, uas tuaj yeem yaj nyob rau hauv cov dej me me lossis mis nyuj. Thaum kuaj pom thiab kho tus mob tuaj lig, qhov tshwm sim ntawm kev mob qog nqaij hlav ntshav hauv lub cev, xws li mob hlwb thiab qeeb qeeb, yuav tshwm sim.

Nws yog ib qho tseem ceeb uas tus me nyuam muaj nws tag nrho thiab pub dawb T4 thiab TSH ntau ntxiv saib xyuas rau tus kws kho mob kuaj xyuas qhov lus teb rau kev kho. Txheeb xyuas kom paub ntau ntxiv txog kev kho mob hypothyroidism hauv kev yees duab hauv qab no: