Cov ntaub ntawv hais tias FDA-Pom Zoo Tshuaj Tshiab los Kho Endometriosis tuaj yeem yog Game-Changer
Zoo Siab
- Orilissa kho tus mob endometriosis li cas?
- Cov kev mob tshwm sim yog dab tsi?
- Cov kab hauv qab?
- Tshuaj xyuas rau
Nyuam qhuav pib lub lim tiam no, Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj tau pom zoo cov tshuaj tshiab uas yuav ua rau muaj kev noj qab haus huv endometriosis yooj yim dua rau ntau dua 10 feem pua ntawm cov poj niam uas nyob nrog qhov mob, thiab qee zaum mob hnyav, mob.(Txog: Lena Dunham Muaj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj Hwj, Lena Dunham Tag Nrho Hysterectomy kom tsis txhob mob Endometriosis)
Kev kho sai sai: "Endometriosis yog ib yam kab mob cuam tshuam rau cov poj niam muaj hnub nyoog me me uas cov kab mob ntawm lub tsev menyuam loj hlob sab nraum lub tsev menyuam," hais tias Sanjay Agarwal, MD, tus xibfwb ntawm obstetrics, gynecology, thiab kev tshawb fawb txog kev yug menyuam ntawm UC San Diego Health. "Cov tsos mob tuaj yeem sib txawv tab sis nws feem ntau cuam tshuam nrog lub sijhawm mob thiab mob nrog kev sib deev-cov tsos mob no tuaj yeem ua rau muaj kev phom sij heev." (Endometriosis kuj tuaj yeem ua rau muaj menyuam tsis taus. Thaum ntxov xyoo no, Halsey tau qhib txog kev khov nws lub qe ntawm 23 vim yog nws qhov endometriosis.)
Muab endometriosis cuam tshuam rau 200 lab tus poj niam thoob ntiaj teb, cov kws kho mob tseem paub me ntsis txog qhov ua rau mob txhab. "Peb tsis paub tseeb tias vim li cas qee tus poj niam tsim nws thiab lwm tus tsis ua lossis vim li cas hauv qee tus poj niam nws tuaj yeem ua rau tus neeg mob zoo thiab rau lwm tus nws tuaj yeem ua rau mob hnyav heev," Zev Williams, MD, Ph.D ., Tus Thawj Saib Xyuas Haujlwm ntawm Kev Loj Hlob Endocrinology thiab Ntxiv Menyuam Ntxiv ntawm Columbia University Medical Center.
Dab tsi kws kho mob paub yog "estrogen nyhav ua rau tus kab mob thiab cov tsos mob tsis zoo," hais tias Dr. Agarwal, uas yog vim li cas endometriosis feem ntau ua rau lub sijhawm mob ntau heev. Nws yog lub voj voog vicious, ntxiv Dr. Williams. "Cov kab mob ua rau mob, uas ua rau lub cev tsim cov tshuaj estrogen, uas ua rau mob ntau dua, thiab lwm yam," nws piav qhia. (Txog: Julianne Hough Hais Tawm Txog Nws Kev Tawm Tsam Nrog Endometriosis)
"Ib ntawm lub hom phiaj ntawm kev kho mob yog txhawm rau txhawm rau txhawm rau lub voj voog no los ntawm kev siv cov tshuaj uas txo qis qhov mob lossis muaj cov tshuaj estrogen," Dr. Williams hais. "Yav dhau los, peb tau ua qhov no nrog yam xws li tshuaj tiv thaiv kev yug menyuam uas ua rau poj niam cov tshuaj qib qis lossis siv cov tshuaj zoo li Motrin, uas yog cov tshuaj tiv thaiv kab mob."
Lwm txoj kev kho mob yog txwv tsis pub lub cev los ntawm kev tsim cov tshuaj estrogen ntau nyob rau hauv thawj qhov chaw-ib txoj kev uas yav tas los tau ua los ntawm kev txhaj tshuaj, hais tias Dr. Williams. Qhov no yog raws nraim li cas Orilissa, cov tshuaj tshiab tau pom zoo los ntawm FDA, ua haujlwm-tsuas yog hauv daim ntawv tshuaj txhua hnub.
Cov kws kho mob hais tias ntsiav tshuaj, uas tau pom zoo los ntawm FDA ua ntej lub asthiv no thiab xav tias yuav muaj nyob rau thaum pib lub Yim Hli, tuaj yeem yog kev hloov pauv kev ua si rau cov poj niam uas muaj mob hnyav rau mob endometriosis. Dr. Agarwal hais tias "Qhov no yog ib qho loj hauv ntiaj teb kev noj qab haus huv ntawm poj niam." Nws hais tias "Kev hloov pauv tshiab hauv thaj chaw endometriosis yeej tsis muaj nyob rau ntau caum xyoo, thiab cov kev kho mob uas peb tau ua yog qhov nyuaj," nws hais. Thaum cov tshuaj yog xov xwm zoo siab, tus nqi rau cov neeg mob tsis muaj ntawv pov hwm tsis yog. Kev muab tshuaj plaub lub lis piam yuav raug nqi $ 845 yam tsis muaj ntawv pov hwm, tshaj tawm Chicago Tribune.
Orilissa kho tus mob endometriosis li cas?
"Ib txwm lub paj hlwb ua rau zes qe menyuam ua estrogen, uas ua rau cov kab mob uterine-thiab endometriosis lesions-loj hlob," piav qhia Dr. Williams, uas tau sab laj nrog lub tuam txhab tshuaj tom qab Orilissa thaum nws tab tom tsim. Orilissa maj mam suppresses endometriosis-ua rau cov tshuaj estrogen los ntawm "thaiv lub hlwb los ntawm kev xa cov teeb liab mus rau zes qe menyuam los tsim cov tshuaj estrogen," nws hais.
Raws li cov tshuaj estrogen taper tawm, yog li qhov mob endometriosis. Hauv FDA-kev soj ntsuam kev sim tshuaj ntawm Orilissa, uas koom nrog yuav luag 1,700 tus poj niam uas mob nruab nrab mus rau qhov mob endometriosis hnyav, cov tshuaj txo qis peb hom mob endometriosis: mob txhua hnub, mob lub sijhawm, thiab mob thaum pw ua ke.
Cov kev mob tshwm sim yog dab tsi?
Cov kev kho mob tam sim no rau endometriosis feem ntau tuaj nrog cov kev mob tshwm sim xws li los ntshav tsis tu ncua, pob txuv, hnyav nce, thiab kev nyuaj siab. "Vim tias cov tshuaj tshiab no txo cov tshuaj estrogen maj mam, nws yuav tsum tsis muaj qhov zoo ib yam ntawm cov kev mob tshwm sim uas lwm yam tshuaj tuaj yeem muaj," hais tias Dr.
Feem ntau cov kev mob tshwm sim me me-tab sis vim tias nws ua rau cov tshuaj estrogen poob qis, Orilissa tuaj yeem ua rau cov tsos mob zoo li cev ntas xws li kub nyhiab, txawm hais tias cov kws tshaj lij tsis muaj pov thawj pom tias nws tuaj yeem ncaws koj mus rau lub cev ntas ntxov.
Qhov kev pheej hmoo tseem ceeb yog tias cov tshuaj tuaj yeem ua rau cov pob txha qis. Qhov tseeb, FDA pom zoo tias cov tshuaj yuav tsum tsuas yog noj rau qhov siab tshaj plaws ntawm ob xyoos, txawm tias qhov koob tshuaj qis tshaj plaws. Dr. Williams hais tias "Qhov kev txhawj xeeb nrog cov pob txha ntom ntom yog qhov nws tuaj yeem ua rau pob txha tawg," Dr. "Qhov no yog ib qho kev txhawj xeeb tshwj xeeb rau cov poj niam thaum lawv muaj hnub nyoog qis dua 35 xyoos thiab nyob rau hauv lub xyoo ntawm kev txhim kho lawv cov pob txha pob txha ceev." (Xov xwm zoo: Kev qoj ib ce tuaj yeem pab tswj koj cov pob txha ceev thiab txo cov pob txha.)
Yog li, puas yog txhais tau tias Orilissa tsuas yog pab ob xyoos pab tau zoo tshaj? Zoo. Thaum koj tso tseg cov tshuaj, cov kws tshaj lij hais tias qhov mob yuav pib maj mam rov qab los. Tab sis txawm tias ob xyoos tsis muaj mob yog qhov tseem ceeb. "Lub hom phiaj ntawm kev tswj cov tshuaj hormones yog txhawm rau ncua kev loj hlob ntawm qhov txhab endometriosis kom txo tau cov tsos mob thiab tiv thaiv qhov xav tau kev phais lossis ncua sijhawm thaum xav tau kev phais," hais tias Dr. Williams.
Tom qab koj tau siv koj lub sijhawm siv tshuaj ntau dhau lawm, cov ntaub ntawv feem ntau xav kom rov qab mus rau kev kho mob xws li kev tiv thaiv kev yug menyuam los pab tiv thaiv qhov kev loj hlob, Dr. Williams hais.
Cov kab hauv qab?
Orilissa tsis yog cov mos txwv khawv koob, thiab tsis yog nws kho rau endometriosis (hmoov, tseem tsis muaj ib qho). Tab sis cov tshuaj tau txais kev pom zoo tshiab no sawv cev rau ib kauj ruam loj hauv kev kho mob, tshwj xeeb tshaj yog rau cov poj niam uas mob hnyav, Dr. Agarwal hais. "Lub sijhawm no yog lub sijhawm zoo siab heev rau cov poj niam uas muaj endometriosis."