Tus Sau: Marcus Baldwin
Hnub Kev Tsim: 13 Lub Rau Hlis Ntuj 2021
Hloov Hnub: 15 Lub Kaum Ib Hli Ntuj 2024
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Spironolactone (Aldactone) Nursing Pharmacology Considerations
Daim Duab: Spironolactone (Aldactone) Nursing Pharmacology Considerations

Zoo Siab

Spironolactone, paub ua lag luam li Aldactone, ua cov diuretic, nce kev tshem tawm cov dej los ntawm cov zis, thiab raws li cov tshuaj tiv thaiv ntshav, thiab tuaj yeem siv rau hauv kev kho mob ntshav siab, o cuam tshuam rau cov teeb meem hauv kev ua haujlwm ntawm lub plawv lossis kab mob. Piv txwv hauv daim siab thiab lub raum, hypokalemia los yog hauv kev kho mob ntawm hyperaldosteronism, piv txwv.

Qee qhov xwm txheej, txoj kev hais daws no tuaj yeem kho rau pob txuv thiab tiv thaiv cov plaub hau ploj, txawm li cas los xij cov ntawv thov no tsis yog ib feem ntawm cov cim tseem ceeb rau spironolactone, tsis hais txog hauv pob ntim nrog.

Spironolactone tuaj yeem muas tau hauv cov chaw muag tshuaj, rau tus nqi kwv yees li 14 txog 45 reais, nyob ntawm seb tus neeg xaiv lub hom lag luam lossis hom, xav tau kev nthuav qhia los ntawm cov tshuaj noj.

Dab tsi yog nws rau

Spironolactone yog qhia rau:


  • Qhov tseem ceeb tawg siab;
  • Edema mob los ntawm lub siab, lub raum lossis daim siab mob;
  • Idiopathic edema;
  • Kev pab txhawb nqa hauv kev mob ntshav siab;
  • Hypokalemiaemia thaum lwm yam kev ntsuas tau txiav txim siab tsis tsim nyog lossis tsis txaus;
  • Kev tiv thaiv ntawm hypokalemia thiab hypomagnesaemia nyob rau hauv cov neeg noj diuretics;
  • Kev kuaj mob thiab kho tus mob hyperaldosteronism.

Kawm txog lwm hom kev siv tshuaj tua kab mob thiab kawm paub lawv ua haujlwm li cas.

Yuav noj li cas

Qhov ntau npaum li cas yog nyob ntawm cov teeb meem yuav tsum tau kho:

1. Qhov tseem ceeb tawg

Cov koob tshuaj li niaj zaus yog 50 mg / hnub rau 100 mg / hnub, uas nyob rau hauv cov kis lossis cov mob hnyav tuaj yeem maj mam nce ntxiv, nyob rau hauv ncua sij hawm ntawm ob lub lis piam, txog 200 mg / hnub. Txoj kev kho yuav tsum txuas ntxiv tsawg kawg yog ob lub lis piam txhawm rau paub meej cov lus teb txaus rau kev kho. Qhov tshuaj yuav tsum tau hloov kho raws li qhov xav tau.

2. Kev Zoo Siab Tsis Txaus Ntseeg

Qhov pom zoo kom pib noj txhua hnub yog 100 mg hauv koob los yog faib ib zaug, uas tuaj yeem sib txawv ntawm 25 mg thiab 200 mg rau ib hnub. Koob tshuaj saib xyuas ib txwm yuav tsum tau txiav txim rau txhua tus neeg.


3. Mob siab ua haujlwm

Yog tias cov tshuaj urinary sodium / urinary potassium muaj ntau dua 1, qhov kev siv ib txwm yog 100 mg / hnub. Yog tias qhov sib piv no tsawg dua 1, qhov koob tshuaj pom zoo yog 200 mg / hnub rau 400 mg / hnub. Koob tshuaj saib xyuas ib txwm yuav tsum tau txiav txim rau txhua tus neeg.

4. Cov ntsws mob ntsws

Cov koob tshuaj ib txwm muaj rau cov laus yog 100 mg / hnub rau 200 mg / hnub.

5. Edema

Cov koob tshuaj ib txwm yog 100 mg rau ib hnub rau cov neeg laus thiab kwv yees li 3.3 mg rau ib phaus ntawm qhov hnyav tau muab rau hauv ib koob tshuaj. Qhov ntau thiab yuav tsum tau muab kho raws li cov lus teb thiab kev tiv thaiv ntawm txhua tus neeg.

6. Cov Mob Hypokalemia / hypomagnesaemia

Kev noj tshuaj ntawm 25 mg / hnub txog 100 mg / hnub yog pom zoo hauv kev kho mob hypopotassemia thiab / lossis hypomagnesemia induced by diuretics, thaum qhov ncauj potassium thiab / lossis tshuaj ntxiv magnesium tsis txaus.

7. Kev kho mob tshuaj qog ua ntej ntawm Hyperaldosteronism

Thaum kuaj mob ntawm hyperaldosteronism tau zoo los ntawm kev kuaj pom tseeb dua, spironolactone tuaj yeem raug txhaj rau txhua hnub ntawm 100 mg rau 400 mg hauv kev npaj rau kev phais mob.


8. Malignant kub siab

Nws yuav tsum tsuas yog siv los ua kev pabcuam pabcuam thiab thaum muaj kev zais ntau dhau ntawm aldosterone, hypokalemia thiab metabolic alkalosis. Cov koob tshuaj pib yog 100 mg / hnub, uas tuaj yeem nce ntxiv, thaum tsim nyog, ntawm ncua sijhawm ntawm ob lub lis piam, txog li 400 mg / hnub.

Mechanism ntawm kev ua

Spironolactone yog ib qho tshwj xeeb aldosterone antagonist, ua yeeb yaj kiab rau aldosterone-dependant sodium thiab potassium ion pauv chaw, nyob hauv lub raj xa hluav taws xob hauv lub raum, uas ua rau kom sodium thiab dej ntau ntxiv thiab nce potassium kev tuav cia.

Muaj kev phiv ntau

Qee qhov kev mob tshwm sim ntawm spironolactone yuav suav nrog benign mis neoplasm, leukopenia, thrombocytopenia, electrolyte cuam tshuam, kev hloov hauv libido, tsis meej pem, kiv taub hau, mob plab thiab xeev siab, ua haujlwm lub siab ua haujlwm tsis txaus, Steve-Johnson syndrome, lom tshuaj lom hauv lub cev, mob ua pob, plaub hau poob, hypertrichosis, khaus, khaus, pob txha caj ntswm, mob raum tsis ua hauj lwm, mob mis, mob coj khaub ncaws, mob caj dab thiab malaise.

Cov Yuav Tsum Tau Ua

Spironolactone yuav tsum tsis txhob siv los ntawm cov neeg mob siab rau lub cev sib xyaw, cov neeg mob raum tsis ua haujlwm, muaj teeb meem rau lub raum kev ua haujlwm, mob anuria, Addison's disease, hyperkalaemia lossis tus uas siv tshuaj kho mob hu ua eplerenone.

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