Nov yog Qhov Kev Pom Zoo Nrog Kev Pab Cuam Tshuam Plasma rau COVID-19 Cov Neeg Mob

Zoo Siab

• Yog li, Txoj Kev Kho Mob Ntshav Qab Zib Dab Tsi, Qhov Tseeb?
• Leej twg tuaj yeem pub Convalescent Plasma rau COVID-19?
• Dab tsi yog Convalescent Plasma Pub Dawb?
• Tshuaj xyuas rau

Txij li thaum lub Peb Hlis lig, tus kab mob kis thoob qhov txhia chaw tau txuas ntxiv qhia lub teb chaws - thiab lub ntiaj teb - tag nrho cov tswv yim tshiab: kev nyob sib nrug deb, cov cuab yeej tiv thaiv tus kheej (PPE), kev sib cuag, tsuas yog hu rau ob peb tug. Nws zoo li yog tias nrog txhua hnub dhau los ntawm (zoo li nyob mus ib txhis) kev kis thoob qhov txhia chaw muaj qhov kev txhim kho tshiab uas muab qhov tseeb ntawm cov nqe lus ntxiv rau cov ntawv txhais lus COVID-19 uas tau loj hlob zuj zus. Ib qho ntawm qhov txuas ntxiv tsis ntev los no rau koj cov lus nplua nuj zuj zus? Convalescent ntshav kho.

Tsis paub? Kuv yuav piav qhia…

Thaum Lub Yim Hli 23, 2020 Tebchaws Asmeskas Cov Khoom Noj thiab Tshuaj Yeeb Tshuaj (FDA) tau tso cai siv xwm txheej ceev thaum lub sijhawm rov qab los ntshav-cov tshuaj tiv thaiv kab mob ntau ntxiv los ntawm cov neeg mob COVID-19 zoo-rau kev kho mob hnyav. Tom qab ntawd, me ntsis ntau dua li ib lub lis piam tom qab, thaum lub Cuaj Hlis 1, Pawg Tswj Xyuas Kev Tiv Thaiv-19 Kev Tiv Thaiv, ib feem ntawm National Institutes of Health (NIH), tau koom nrog kev sib tham, hais tias muaj "cov ntaub ntawv tsis txaus los qhia rau lossis tawm tsam kev siv. ntawm convalescent ntshav rau kev kho mob ntawm COVID-19. "

Ua ntej ua yeeb yam no, cov ntshav ntshav tau muab rau cov neeg mob COVID-19 mob dhau los ntawm Mayo Clinic-led Expanded Access Program (EAP), uas xav kom kws kho mob sau npe mus thov ntshav rau cov neeg mob, raws li FDA. Tam sim no, mus tom ntej, EAP tau xaus thiab tau hloov pauv los ntawm FDA's Emergency Use Authorization (EUA), uas tseem ceeb tso cai rau cov kws kho mob thiab tsev kho mob thov cov ntshav yam tsis tau ua raws li qee yam kev tso npe nkag. Tab sis, raws li tau hais los ntawm NIH cov lus tshaj tawm tsis ntev los no, xav tau kev tshawb fawb ntxiv ua ntej leej twg tuaj yeem ua haujlwm tau zoo (thiab nyab xeeb) pom zoo kom kho mob ntshav qab zib kom zoo raws li kev kho mob uas ntseeg tau ntawm COVID-19.

Kev kho ntshav ntshav kom rov zoo tuaj yeem siv tau ntau dua li qhov muaj peev xwm kho tau rau COVID-19 hauv Asmeskas, tab sis nws yog dab tsi? Thiab koj tuaj yeem pub ntshav ntshav ntshav rov zoo li cas rau COVID-19 cov neeg mob li cas? Ua ntej, txhua yam koj xav paub.

Yog li, Txoj Kev Kho Mob Ntshav Qab Zib Dab Tsi, Qhov Tseeb?

Ua ntej, dab tsi yog convalescent ntshav? Convalescent (cov lus piav qhia thiab lub npe) yog hais txog ib tus neeg uas rov zoo los ntawm tus kab mob, thiab ntshav ntshav yog daj, kua ntawm cov ntshav uas muaj cov tshuaj tiv thaiv kab mob, raws li FDA. Thiab, yog tias koj tsis tau kawm qib 7 txog qib biology, cov tshuaj tiv thaiv kab mob yog cov protein uas tau tsim los tawm tsam cov kab mob tshwj xeeb tom qab kis tus kab mob ntawd.

Yog li, plasma convalescent tsuas yog cov ntshav los ntawm ib tus neeg uas tau zoo los ntawm tus kab mob - qhov no, COVID-19, hais tias Brenda Grossman, MD, tus thawj coj kho mob ntawm Transfusion Medicine ntawm Tsev Kho Mob Barnes-Jewish, thiab tus xibfwb ntawm Washington University School of Tshuaj nyob rau hauv St. Louis. "Convalescent plasmas tau siv yav dhau los, nrog qib sib txawv ntawm kev ua haujlwm tau zoo, rau ntau yam kab mob sib kis, suav nrog Spanish Flu, SARS, MERS, thiab Ebola," hais tias Dr. Grossman.

Tam sim no, ntawm no yog qhov "kev kho mob" los rau hauv: Thaum cov ntshav tau los ntawm ib tus neeg tau rov zoo, nws tau hloov pauv mus rau tus neeg mob tam sim no (thiab feem ntau mob hnyav) kom cov tshuaj tiv thaiv tuaj yeem cia siab "ua kom tus kab mob zoo thiab muaj peev xwm txhim kho kev tshem tawm tus kab mob. los ntawm lub cev, "hais tias Emily Stoneman, MD, tus kws kho mob tshwj xeeb ntawm University of Michigan hauv Ann Arbor. Hauv lwm lo lus, nws tau siv "los txhawb tus neeg mob lub cev tiv thaiv kab mob thiab cia siab tias yuav txo qhov cuam tshuam ntawm tus mob."

Tab sis, raws li nrog ntau yam hauv lub neej (ugh, yos), sijhawm yog txhua yam. "Nws feem ntau yuav siv li ob lub lis piam rau cov tib neeg muaj tus kab mob COVID-19 los tsim cov tshuaj tiv thaiv no ntawm lawv tus kheej," Dr. Stoneman piav qhia. "Yog tias cov ntshav plasma tau muab rau thaum ntxov thaum muaj mob, nws yuav ua rau lub sijhawm muaj mob thiab tiv thaiv. Cov neeg mob los ntawm kev mob hnyav, "Yog li, thaum xav tau kev tshawb fawb ntxiv los txiav txim siab qhov ua tau zoo ntawm kev kho mob ntshav sib kis, qhov laj thawj tam sim no yog qhov ua ntej tus neeg mob tau txais kev kho mob, muaj feem ntau lawv yuav pom cov txiaj ntsig zoo. (Kawm: Yuav Ua Li Cas Nrog Kev Noj Qab Haus Huv Kev ntxhov siab Thaum lub sijhawm COVID-19, thiab dhau mus)

Leej twg tuaj yeem pub Convalescent Plasma rau COVID-19?

Kev tsim nyog tus naj npawb ib: koj muaj tus mob coronavirus thiab koj muaj qhov kev sim los ua pov thawj nws.

"Cov tib neeg tuaj yeem pub ntshav ntshav yog tias lawv muaj tus kab mob COVID-19 nrog cov ntaub ntawv kuaj mob (xws li nasopharyngeal [nasal] swab lossis kuaj cov tshuaj tiv thaiv zoo), tau zoo zoo, thiab tsis muaj tsos mob tsawg kawg yog ob lub lis piam," raws li Hyunah Yoon, MD, Tus kws kho mob tshwj xeeb ntawm Albert Einstein College of Medicine. (Kuj nyeem: Dab Tsi Qhov Kev Tiv Thaiv Lub Cev Lub Cev Muaj Qhov Zoo Li Cas?)

Tsis muaj kev kuaj pom tseeb tab sis ntseeg siab tias koj tau ntsib tus mob coronavirus? Xov xwm zoo: Koj tuaj yeem teem sijhawm kuaj tshuaj tiv thaiv kab mob hauv koj lub zos American Red Cross thiab, yog tias cov txiaj ntsig tau zoo rau cov tshuaj tiv thaiv kab mob, ua raws li ntawd-uas yog, tau kawg, tsuav yog koj ua tau raws li lwm qhov kev pub dawb, xws li tsis muaj tsos mob. tsawg kawg yog 14 hnub ua ntej pub dawb. Thaum ob lub lis piam yam tsis muaj tsos mob tau pom zoo los ntawm FDA, qee lub tsev kho mob thiab cov koom haum yuav xav kom cov neeg pub dawb tsis muaj tsos mob rau 28-hnub, hais tias Dr. Grossman

Dhau qhov ntawd, Asmeskas Red Cross kuj tseem xav kom cov neeg pub ntshav sib kis tau tsawg kawg yog 17 xyoo, hnyav 110 lbs, thiab ua tau raws li lub koom haum cov kev xav pub dawb. (Saib daim ntawv qhia no rau kev muab ntshav los saib seb koj puas ua tau zoo raws li qhov yuav tsum tau ua.) Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias thaum lub sijhawm tsis muaj kev sib kis, koj tuaj yeem (thiab, TBH, yuav tsum) kuj pub ntshav plasma siv rau. Lwm yam kev kho mob rau, hais, cov neeg mob qog noj ntshav thiab hlawv thiab raug mob raug mob, raws li New York Blood Center.

Dab tsi yog Convalescent Plasma Pub Dawb?

Thaum koj tau teem sijhawm ntsib nrog koj lub chaw pabcuam pub dawb hauv ib cheeb tsam, nws yog lub sijhawm los npaj. Txhua yam uas xav tau tiag tiag, txawm li cas los xij, yog haus dej txaus (tsawg kawg 16oz.) Thiab noj cov zaub mov muaj protein ntau thiab muaj cov hlau (nqaij liab, ntses, taum, zaub ntsuab) cov xuab moos ua ntej koj mus ntsib kws kho mob kom tsis txhob muaj lub cev qhuav dej, yuag yuag, thiab kiv taub hau, raws li American Red Cross.

Suab paub? Tias yog vim li cas ntshav thiab ntshav pub dawb zoo sib xws - tshwj tsis yog ua qhov pub dawb. Yog tias koj tau muab ntshav, koj paub tias cov kua ntws tawm ntawm koj txhais caj npab thiab mus rau hauv lub hnab thiab tas yog keeb kwm. Kev pub ntshav plasma yog me ntsis ntxiv, yuam kev, nyuaj. Thaum lub sijhawm pub ntshav ntshav nkaus xwb, cov ntshav tau rub los ntawm ib txhais caj npab thiab xa los ntawm lub tshuab thev naus laus zis uas sau cov ntshav thiab tom qab ntawd xa cov qe ntshav liab thiab cov platelets rov qab-nrog rau qee cov kua ntsev (aka dej ntsev)-rov qab rau hauv koj lub cev. Qhov no yog qhov tseem ceeb vim ntshav yog 92 feem pua ​​dej, raws li American Red Cross, thiab cov txheej txheem pub dawb ua rau koj muaj kev pheej hmoo rau lub cev qhuav dej (ntau ntxiv hauv qab no). Tag nrho cov txheej txheem pub dawb yuav tsum siv sijhawm li ib teev thiab 15 feeb (tsuas yog kwv yees li 15 feeb ntev dua li kev pub ntshav nkaus xwb), raws li Asmeskas Red Cross.

Kuj zoo ib yam li kev pub ntshav, qhov tshwm sim ntawm kev muab ntshav yog qhov tsawg - tom qab tag nrho, koj yuav tsum muaj kev noj qab haus huv tag nrho kom tsim nyog tau txais thawj zaug. Uas tau hais tias, raws li tau hais los saum no, lub cev qhuav dej yog qhov ua tau ntau heev. Thiab yog vim li cas, nws yog ib qho tseem ceeb uas koj yuav tsum nce koj cov dej kom ntau nyob rau cov hnub tom qab thiab ua kom pom tseeb ntawm kev nqa hnyav thiab qoj ib ce tsawg kawg ntawm hnub ntawd. Thiab tsis txhob txhawj xeeb txog koj lub cev ua qee cov kua dej tseem ceeb, vim nws tuaj yeem (thiab ua) hloov cov ntshav lossis ntshav hauv 48 teev.

Txog rau koj qhov kev pheej hmoo ntawm COVID-19? Qhov ntawd yuav tsum tsis txhob txhawj xeeb ntawm no. Feem ntau cov chaw pabcuam ntshav tau ua tiav los ntawm kev teem sijhawm tsuas yog txhawm rau txhawb nqa kev coj noj coj ua nyob deb tshaj plaws thiab tau ua raws li kev tiv thaiv ntxiv raws li tau hais tseg los ntawm Lub Chaw Tiv Thaiv thiab Tiv Thaiv Kab Mob (CDC).

Cov ntaub ntawv hauv zaj dab neeg no muaj tseeb raws li lub sijhawm nias. Raws li kev hloov tshiab hais txog tus mob coronavirus COVID-19 txuas ntxiv mus, nws muaj peev xwm hais tias qee cov ntaub ntawv thiab cov lus pom zoo hauv zaj dab neeg no tau hloov pauv txij li kev tshaj tawm thawj zaug. Peb txhawb kom koj mus xyuas tsis tu ncua nrog cov peev txheej xws li CDC, WHO, thiab koj lub chaw saib xyuas kev noj qab haus huv hauv zos kom paub cov ntaub ntawv tshiab thiab cov lus pom zoo.

Tshuaj xyuas rau