Angiokeratoma

Zoo Siab

• Dab tsi yog muaj ntau hom?
• Cov tsos mob zoo li cas?
• Dab tsi ua rau mob angiokeratoma?
• Yuav kuaj pom tus mob angiokeratoma li cas?
• Yuav kho nws li cas?
• Qhov kev xam pom rau cov neeg mob caj dab yog dab tsi?

Dab tsi yog angiokeratoma?

Angiokeratoma yog ib qho mob uas me me, tsaus nti tshwm rau ntawm daim tawv nqaij. Lawv tuaj yeem tshwm sim txhua qhov chaw ntawm koj lub cev. Cov txhab no tshwm sim thaum cov hlab ntshav me me hu ua capillaries dilate, lossis nthuav dav, ze rau thaj tsam ntawm koj cov tawv nqaij.

Angiokeratomas yuav hnov ​​ntxhib rau tus neeg kov. Lawv feem ntau tshwm sim ua tej pawg rau ntawm daim tawv nqaij ib ncig ntawm:

• chaw mos
• scrotum
• rab qau
• labia majora

Lawv tuaj yeem yuam kev tawm pob khaus, mob qog tawv nqaij, lossis muaj mob xws li mob pob txha mos lossis mob ua pob. Feem ntau, cov tshuaj angiokeratomas tsis muaj kev phom sij thiab tsis tas yuav kho mob.

Angiokeratomas qee zaum tuaj yeem yog cov tsos mob ntawm qhov mob hauv qab, xws li tsis tshua muaj caj ces tsis paub hu ua Fabry disease (FD). Koj yuav tsum tau ntsib kws kho mob rau kev kho mob txhawm rau txhawm rau tiv thaiv teeb meem.

Dab tsi yog muaj ntau hom?

Hom mob angiokeratoma yog:

• Raug tshuaj angiokeratoma. Cov no ib leeg tshwm sim ib leeg. Lawv feem ntau pom ntawm koj sab caj npab thiab ceg. Lawv yuav tsis ua rau muaj kev phom sij.
• Angiokeratoma ntawm Fordyce. Cov no tshwm sim ntawm daim tawv nqaij ntawm hnoos qeev lossis rab qau. Lawv feem ntau pom nyob ntawm daim tawv nqaij ntawm cov pawg loj. Hom no tuaj yeem loj hlob ntawm tus pojniam lub cev xeeb tub. Lawv tsis ua rau muaj kev phom sij, tab sis nquag muaj ntshav yog tias lawv khawb.
• Angiokeratoma ntawm Mibelli. Cov txiaj ntsig no los ntawm cov roj ntsha uas tau tso ze rau qhov epidermis, lossis txheej txheej sab saum toj ntawm koj cov tawv nqaij. Lawv tsis tsim kev puas tsuaj. Hom no nyhav rau tuab thiab tawv thaum lub sij hawm nyob rau hauv tus txheej txheem hu ua hyperkeratosis.
• Angiokeratoma circumscriptum. Qhov no yog daim ntawv tsis tshua zoo nkauj uas pom tshwm hauv pawg ntawm koj ceg lossis npog tas ib ce. Koj tuaj yeem yug nrog hom no. Nws zoo li morph hauv cov tsos thaum lub sijhawm ua haujlwm, ua tsaus dua lossis noj cov duab sib txawv.
• Angiokeratoma corporis diffusum. Hom no yog tsos mob ntawm FD. Nws tuaj yeem tshwm sim nrog lwm qhov kev cuam tshuam lysosomal, uas cuam tshuam li cas lub hlwb ua haujlwm. Cov mob no tsis tshua muaj thiab muaj lwm cov tsos mob pom tau, xws li hlawv ntawm txhais tes thiab taw lossis teeb meem tsis pom kev. Cov angiokeratomas feem ntau tshwm sim puag ncig lub cev qis. Lawv tuaj yeem tshwm sim nyob txhua qhov chaw ntawm hauv qab ntawm koj lub caj dab mus rau koj sab ncej puab.

Cov tsos mob zoo li cas?

Tus qauv qhia kiag, qhov loj me thiab xim tuaj yeem sib txawv. Koj tseem tuaj yeem muaj cov tsos mob ntxiv yog tias koj muaj tus mob cuam tshuam, xws li FD.

Feem ntau, angiokeratomas tso saib cov tsos mob hauv qab no:

• zoo li me-rau nruab nrab-pob los ntawm 1 millimeter (mm) mus rau 5 hli lossis hauv cov dav, cov qauv zoo li cos
• muaj lub dome-zoo li lub cev
• xav tias tuab lossis nyuaj rau ntawm qhov chaw
• qhia ib leeg lossis hauv pawg tsuas muaj ob peb tus mus txog rau ib puas
• yog xim tsaus, suav nrog liab, xiav, ntshav, lossis xim dub

Angiokeratomas uas nyuam qhuav tshwm sim yuav liab ploog. Cov nqaij me dhau ntawm koj cov tawv nqaij ib pliag feem ntau yuav tsaus dua.

Angiokeratomas ntawm daim tawv nqaij ntawm qhov chaw ntxuav kuj tuaj yeem tshwm nrog rau qhov liab liab thoob plaws thaj tsam ntawm lub qhov quav. Angiokeratomas ntawm cov pob txha mos los yog qhov chaw mos kuj yuav los ntshav yooj yim dua thaum khawb dua li lwm qhov ntawm koj lub cev.

Yog tias koj muaj ib qho mob zoo ib yam li FD uas ua rau mob angiokeratomas tshwm, lwm cov tsos mob koj yuav muaj xws li:

• acroparesthesias, lossis mob hauv koj txhais tes thiab taw
• tinnitus, los yog lub suab nrov nrov hauv koj lub pob ntseg
• corneal opacity, lossis pos huab hauv koj lub zeem muag
• hypohidrosis, lossis tsis tuaj yeem tawm hws kom zoo
• mob hauv koj lub plab thiab lub plab hnyuv
• zoo nkaus li qhov yaum kom tso quav tom qab noj mov

Dab tsi ua rau mob angiokeratoma?

Angiokeratomas tshwm sim los ntawm kev tso pa tawm ntawm cov hlab ntshav ze rau thaj tsam ntawm daim tawv nqaij. Cov tshuaj tiv thaiv angiokeratomas uas yuav tau tshwm sim los ntawm kev raug mob uas yav tas los tau tshwm sim hauv ib cheeb tsam uas lawv tshwm sim

FD kis rau hauv tsev neeg, thiab tuaj yeem ua rau mob hno. Kwv yees li 1 ntawm txhua 40,000 txog 60,000 tus txiv neej muaj FD, raws li Tebchaws Asmeskas Cov Tsev Haujlwm Saib Xyuas Kev Noj Tshuaj ntawm lub chaw saib kabmob.

Lwm yam tshaj li lawv txoj kev koom nrog FD thiab lwm yam kev mob lysosomal, nws tsis yog ib qho tseeb tias vim li cas thiaj li mob taub hau. Cov teeb meem ua tau suav nrog:

• ntshav siab, lossis ntshav siab hauv cov leeg ntshav ze ntawm daim tawv nqaij
• muaj tus mob uas cuam tshuam rau cov hlab ntshav hauv zos, xws li mob pob txha nqaj ntshav, hemorrhoids, lossis varicocele (thaum leeg mob hauv qhov nqaij txhaws ua kom dav)

Yuav kuaj pom tus mob angiokeratoma li cas?

Angiokeratomas feem ntau tsis muaj kev phom sij. Koj tsis tas yuav tsum tau mus ntsib kws kho mob txhawm rau kuaj mob.

Tab sis yog tias koj pom lwm cov tsos mob, xws li nquag los ntshav lossis tsos mob ntawm FD, mus ntsib koj tus kws kho mob tam sim ntawd kom kuaj thiab kho mob. Koj tuaj yeem xav ntsib koj tus kws kho mob yog tias koj xav tias qhov chaw uas zoo li mob angiokeratoma tuaj yeem yog mob cancer.

Koj tus kws kho mob yuav muab ib qho nqaij coj los kuaj ntawm tus mob angiokeratoma los kuaj. Qhov no yog hu ua biopsy. Thaum lub sijhawm cov txheej txheem no, koj tus kws kho mob yuav ua kom tshem tawm, lossis txiav tawm, mob caj dab los ntawm koj cov tawv nqaij kom tshem nws tawm rau kev txheeb xyuas. Qhov no tuaj yeem koom nrog koj tus kws kho mob siv tawv taub hau kom tshem tawm cov kev mob pob txha taub hau los ntawm nws lub hauv paus ntawm daim tawv nqaij.

Koj tus kws kho mob tseem yuav pom zoo kom kuaj GLA cov kab mob seb koj puas muaj FD. FD tshwm sim los ntawm kev sib pauv hauv cov noob no.

Yuav kho nws li cas?

Angiokeratomas feem ntau tsis tas yuav kho yog tias koj tsis muaj kev mob siab lossis mob ib ce. Koj tuaj yeem xav tau lawv tshem tawm yog tias lawv nquag los ntshav lossis ua kom zoo nkauj vim li cas. Hauv qhov no, muaj ntau txoj kev kho mob:

• Kev thaij duab hluav taws xob thiab kho tus mob (ED&C). Koj tus kws kho mob loog ib ncig thaj tsam ntawm angiokeratomas nrog cov tshuaj loog hauv zos, tom qab ntawd siv hluav taws xob ntsuas thiab khoom siv los txhuam cov pob tawm thiab tshem cov nqaij mos.
• Laser tshem tawm. Koj tus kws kho mob siv cov lasers, xws li lub ntsej muag zas hluav taws xob, kom rhuav tshem cov hlab ntshav uas ua rau mob angiokeratomas.
• Tshuaj Kho Mob. Koj tus kws kho mob tso cov tshuaj angiokeratomas thiab cov nqaij mos uas nyob ib puag ncig thiab tshem lawv.

Kev kho mob rau FD kuj suav nrog kev siv tshuaj, xws li:

• Agalsidase beta (Fabrazyme). Koj yuav tau txais cov tshuaj Fabrazyme tsis tu ncua los pab koj lub cev rhuav tshem cov rog rog ntxiv vim yog ploj vim muaj enzyme los ntawm GLA kev hloov pauv.
• Neurontin (Gabapentin) lossis carbamazepine (Tegretol). Cov tshuaj no tuaj yeem kho tus mob tes thiab ko taw.

Koj tus kws kho mob tseem yuav qhia koj kom pom cov kws tshwj xeeb rau lub siab, raum, lossis cov tsos mob ntawm lub paj hlwb ntawm FD, ib yam nkaus.

Qhov kev xam pom rau cov neeg mob caj dab yog dab tsi?

Angiokeratomas tsis yog feem ntau ua rau muaj kev txhawj xeeb. Mus ntsib koj tus kws kho mob yog tias koj pom tias yuav los ntshav lossis raug mob rau lub ntsej muag mob taub hau, lossis yog koj xav tias muaj ib yam kev mob uas ua rau koj tsis xis nyob lossis mob.