Alpha-Fetoprotein (AFP) Kev Xeem

Zoo Siab

• Qhov kev ntsuam xyuas alpha-fetoprotein (AFP) yog dab tsi?
• Nws siv rau dab tsi?
• Vim li cas kuv thiaj xav tau qhov kev ntsuas AFP?
• Dab tsi tshwm sim thaum kuaj AFP?
• Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?
• Puas muaj kev pheej hmoo rau kev kuaj?
• Cov txiaj ntsig li cas?
• Puas muaj lwm yam ntxiv uas kuv xav paub txog qhov kev ntsuas AFP?
• Ua tim khawv

Qhov kev ntsuam xyuas alpha-fetoprotein (AFP) yog dab tsi?

Alpha-fetoprotein (AFP) yog ib qho protein tsim nyob rau hauv lub siab ntawm kev tsim tus me nyuam. Thaum lub sijhawm menyuam mos txoj kev loj hlob, qee qhov AFP kis ntawm tus niam mis thiab nkag mus rau leej niam cov ntshav. Qhov kev ntsuas AFP ntsuas theem ntawm AFP hauv cov poj niam cev xeeb tub hauv lub hlis thib ob ntawm cev xeeb tub. Ntau dhau los lossis tsawg dhau AFP ntawm leej niam cov ntshav tej zaum yuav yog lub cim ntawm kev yug ua neeg tsis taus lossis lwm yam mob. Cov no suav nrog:

• Lub leeg cov leeg ntshav tsis zoo, ib qho mob uas ua rau muaj kev loj hlob ntawm tus menyuam lub hlwb thiab / lossis tus txha nqaj qaum
• Down syndrome, kev mob caj ces uas ua rau lub hlwb xiam hlwb thiab kev loj hlob qeeb
• Menyuam ntxaib lossis yug tau ntau tus, vim muaj ntau dua ib tus menyuam muaj AFP
• Kev ntsuas nyiaj txiag ntawm hnub tim, vim tias qib hauv Qib pauv hloov thaum cev xeeb tub

Lwm lub npe: AFP Niam; Niam Serum AFP; msAFP npo

Nws siv rau dab tsi?

Kev kuaj ntshav hauv AFP yog siv los kuaj xyuas tus menyuam hauv plab kom muaj kev pheej hmoo ntawm kev yug menyuam thiab cov teeb meem ntawm caj ces, xws li cov leeg tsis muaj ntshav lossis cov leeg mob.

Vim li cas kuv thiaj xav tau qhov kev ntsuas AFP?

Lub Koom Haum Asmeskas Cev Xeeb Tub hais tias txhua tus poj niam cev xeeb tub yuav tsum raug kuaj qhov ntsuas qee lub sijhawm thaum hnub tim 15 thiab 20 lub lim tiam ntawm cev xeeb tub. Kev ntsuam xyuas yuav pom zoo tshwj xeeb yog tias koj:

• Muaj ib tse neeg muaj keeb kwm muaj keeb kwm tsis zoo
• Yog 35 xyoos rov saud
• Muaj ntshav qab zib

Dab tsi tshwm sim thaum kuaj AFP?

Tus kws kho mob yuav kuaj ntshav ntawm txoj hlab ntshav hauv koj txhais caj npab, siv rab koob me me. Tom qab cov koob raug tso nkag, cov ntshav me me yuav raug sau rau hauv lub khob kuaj lossis vial. Koj tuaj yeem hnov ​​me ntsis thaum cov koob nkag mus lossis tawm. Qhov no feem ntau yuav siv sijhawm tsawg dua tsib feeb.

Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?

Koj tsis tas yuav muaj kev npaj tshwj xeeb rau qhov kev xeem ntawv AFP.

Puas muaj kev pheej hmoo rau kev kuaj?

Muaj feem ntau pheej hmoo heev rau koj lossis koj tus menyuam nrog kuaj ntshav AFP. Koj yuav muaj mob me lossis doog ntshav ntawm qhov chaw tso rab koob, tab sis feem ntau cov tsos mob ploj mus sai. Lwm qhov kev sim hu ua amniocentesis muab qhov kev kuaj mob muaj tseeb tshaj ntawm Tus Mob Down thiab lwm yam kev mob tsis zoo, tab sis kev sim no muaj qhov pheej hmoo me me uas ua rau nchuav menyuam.

Cov txiaj ntsig li cas?

Yog tias koj cov txiaj ntsig tau qhia tau siab dua li cov qib AFP ib txwm, nws yuav txhais tau tias koj tus menyuam muaj cov hlab ntsha tsis zoo xws li tus txha nqaj qaum, qhov mob uas cov pob txha tsis ua haujlwm ze ntawm tus txha caj qaum, lossis anencephaly, uas mob lub hlwb tsis txhim kho zoo.

Yog tias koj cov txiaj ntsig tau tshwm sim qis dua li AFP cov qib qis, nws yuav txhais tau tias koj tus menyuam muaj kev mob caj ces xws li Down syndrome, ib qho mob uas ua rau muaj kev txawj ntse thiab loj hlob.

Yog tias koj qib AFP tsis zoo, nws tsis tas txhais tias yuav muaj teeb meem nrog koj tus menyuam. Tej zaum nws txhais tau tias koj muaj ntau dua ib tus menyuam lossis koj hnub tas los tsis yog lawm. Koj kuj tseem tuaj yeem tau txais qhov tshwm sim tsis tseeb. Nov txhais tau tias koj cov txiaj ntsig tau los ua teeb meem, tab sis koj tus menyuam noj qab nyob zoo. Yog tias koj cov txiaj ntsig pom tau siab dua lossis qis dua qib AFP, koj yuav muaj feem tau kuaj ntau dua kom pab ntsuas tus mob.

Kawm paub ntau ntxiv txog cov kev sim hauv chaw soj ntsuam, cov chaw siv ntsuas, thiab nkag siab cov txiaj ntsig tau.

Puas muaj lwm yam ntxiv uas kuv xav paub txog qhov kev ntsuas AFP?

AFP cov kev ntsuam xyuas feem ntau yog ib feem ntawm cov kev ntsuas ua ntej hu ua ntau yam cim lossis ntsuas triple kev tshuaj ntsuam. Ntxiv rau AFP, kev tshuaj ntsuam peb npaug nrog rau kev sim rau hCG, ib yam tshuaj uas tsim los ntawm cov me nyuam, thiab estriol, ib hom tshuaj los ntawm estrogen ua los ntawm tus menyuam. Cov kev kuaj no tuaj yeem pab tshawb txog Down syndrome thiab lwm yam kev mob hauv lub cev.

Yog tias koj muaj kev pheej hmoo siab rau kev yug menyuam nrog qee qhov kev xeeb me nyuam, koj tus kws kho mob tseem yuav pom zoo kom ntsuas cov ntawv tshiab hu ua DNA-tsis muaj cell (cfDNA). Nov yog kev kuaj ntshav uas tuaj yeem muab thaum ntxov txog 10^th lub lim tiam ntawm cev xeeb tub. Nws tuaj yeem qhia tau yog tias koj tus menyuam muaj feem ntau yuav muaj tus mob Down syndrome lossis qee yam kev mob caj ces.

Ua tim khawv

1. American Cev xeeb Tub Lub Koom Haum [Is Taws Nem]. Irving (TX): Lub Koom Haum Asmeskas Kev Xeeb Tub; c2017. Ntsuam Xyuas Ntshav Niam Txiv Alpha-Fetoprotein Kev Tshuaj Ntsuam Xyuas (MSAFP) [hloov tshiab 2016 Sep 2; raug nplua 2017 Jun 5]; [txog 3 ntxaij]. Muaj los ntawm: http://americanpregnancy.org/prenatal-testing/maternal-serum-alpha-fetoprotein- tshuaj ntsuam
2. American Cev xeeb Tub Lub Koom Haum [Is Taws Nem]. Irving (TX): Lub Koom Haum Asmeskas Kev Xeeb Tub; c2017. Triple Screen Test [kho tshiab 2016 Sep 2; raug nplua 2017 Jun 5]; [txog 3 ntxaij]. Muaj los ntawm: http://americanpregnancy.org/prenatal-testing/triple-screen-test/
3. Cov ntxa JC, Miller KE, Cov Neeg Muag Khoom AD. Ntsuas Poj Niam Ntsuam Xyuas Ntsuas Ntsuas Ntsuas Kev Ntsuas Kab Mob thaum Cev Xeeb Tub. Am Nkaub Tus Kws Kho Mob [Internet]. 2002 Mar 1 [raug nplua 2017 Jun 5]; 65 (5): 915–921. Muaj los ntawm: https://www.aafp.org/afp/2002/0301/p915.html
4. Johns Hopkins Tshuaj Kho Mob [Internet]. Johns Hopkins Tshuaj Kho Mob; Lub Tsev Khaws Kev Noj Qab Haus Huv: Cov Kev Kuaj Thaum Muaj Feem Nrau Thaum Cev Xeeb Tub [hais 2017 Jun 5]; [txog 3 ntxaij]. Muaj los ntawm: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/pregnancy_and_childbirth/common_tests_during_pregnancy_85,p01241
5. Kev Tshuaj Ntsuam Xyuas online [Internet]. Washington D.C .: Koom Haum Asmeskas Rau Chaw Kuaj Mob; c2001–2019. Kev Ntsuas Poj Ntsuam Ntawm Poj Niam, Tshawb Xyuas Thib Ob; [kho tshiab 2019 Tsib Hlis 6; raug nplua 2019 Jun 4]; [txog 2 ntxaij]. Muaj los ntawm: https://labtestsonline.org/tests/maternal-serum-sib-saib-second-trimester
6. Kev Tshuaj Ntsuam Xyuas online [Internet]. Cov Koom Haum Asmeskas rau Chaw Kho Mob Soj Ntsuam; c2001–2017. Cov Lus Txhais: Spina Bifida [hais 2017 2017 5]; [txog 3 ntxaij]. Muaj los ntawm: https://labtestsonline.org/glossary/spina-bifida
7. Merck Los Ntawm Cov Neeg Siv Khoom Siv [Internet]. Kenilworth (NJ): Merck & Co. Inc .; c2017. Kev Ntsuas kabmob Kuaj Menyuam Mosliab [kho tshiab 2017 Jun; raug nplua 2019 Lub Rau Hli 4]; [txog 3 ntxaij]. Muaj los ntawm: http://www.merckmanuals.com/home/women-s- health-issues/detection-of-genetic-disorders/prenatal-diagnostic-testing
8. Lub Chaw hauv National rau Advancing Translational Sciences / Genetic thiab Cov Ntaub Ntawv Kab Mob Tsis Muaj Nqis [Internet]. Gaithersburg (MD): Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Cov Tshuaj Ntshav Neural [kho tshiab 2013 Nov 6; raug nplua 2017 Jun 5]; [txog 3 ntxaij]. Muaj los ntawm: https://rarediseases.info.nih.gov/diseases/4016/neural-tube-defects
9. Teb Chaws Lub Plawv, Lub Ntsws, thiab Koom Haum Ntshav [Internet]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Txoj Kev Kuaj Mob ntshav Dab Tsi Zoo Li Cas? [kho tshiab 2012 Jan 6; raug nplua 2017 Jun 5]; [txog 5 ntxaij]. Muaj los ntawm: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
10. Teb Chaws Lub Plawv, Lub Ntsws, thiab Koom Haum Ntshav [Internet]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Dab Tsi Yuav Cia Siab Nrog Kev Ntshav [kho tshiab 2012 Jan 6; raug nplua 2017 Jun 5]; [txog 4 ntxaij]. Muaj los ntawm: https://www.nhlbi.nih.gov/health-topics/blood-tests
11. University of Rochester Medical Center [Internet]. Rochester (NY): Tsev kawm qib siab Rochester Medical Center; c2017. Cov Ntawv Teev Kev Noj Qab Haus Huv: Alpha-fetoprotein (AFP) [raug muab 2017 Jun 5]; [txog 2 ntxaij]. Muaj los ntawm: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid ;=P02426
12. University of Rochester Medical Center [Internet]. Rochester (NY): Tsev kawm qib siab Rochester Medical Center; c2017. Kev Noj Qab Haus Huv Phau Ntawv Teev Npe: Alpha-fetoprotein (Ntshav) [hais tawm 2017 Jun 5]; [txog 2 ntxaij]. Muaj los ntawm: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid ;=alpha_fetoprotein_maternal_blood
13. UW Kev Noj Qab Haus Huv [Is Taws Nem]. Madison (WI): University of Wisconsin Cov Tsev Kho Mob thiab Chaw Kho Mob; c2017. Cov Ntaub Ntawv Noj Qab Haus Huv: Alpha-Fetoprotein (AFP) hauv ntshav [hloov tshiab 2016 Jun 30; raug nplua 2017 Jun 5]; [txog 5 ntxaij]. Muaj los ntawm: https://www.uwhealth.org/health/topic/medicaltest/alpha-fetoprotein-afp-in-blood/hw1663.html
14. UW Kev Noj Qab Haus Huv [Is Taws Nem]. Madison (WI): University of Wisconsin Cov Tsev Kho Mob thiab Chaw Kho Mob; c2017. Cov Ntaub Ntawv Kev Noj Qab Haus Huv: Kev soj ntsuam peb zaug lossis plaub for for ntawm cov neeg muaj mob thaum yug [kho tshiab 2016 Jun 30; raug nplua 2017 Jun 5]; [txog 5 ntxaij]. Muaj los ntawm: https://www.uwhealth.org/health/topic/special/maternal-serum-triple-or-quadruple-sib-hwm-test/ta7038.html#ta7038-sec

Cov ntaub ntawv ntawm lub xaib no yuav tsum tsis txhob siv los hloov chaw kho mob lossis tswv yim kho mob. Hu rau kws kho mob yog tias koj muaj lus nug txog koj txoj kev noj qab haus huv.