Txhaj Tshuaj Alemtuzumab (Ntau Hom Sclerosis)

Zoo Siab

• Alemtuzumab txhaj tshuaj yog siv los kho cov neeg laus nrog ntau yam mob sclerosis (MS; tus kabmob uas cov hlab ntsha tsis ua haujlwm zoo thiab tib neeg yuav muaj qhov tsis muaj zog, ua tsis taus pa, tsis tuaj yeem ua haujlwm rau cov leeg, thiab muaj teeb meem ntawm lub zeem muag, hais lus thiab zais zis) uas tsis zoo nrog tsawg dua ob lossis ntau dua MS tshuaj noj suav nrog:
• Ua ntej tau txais kev txhaj tshuaj alemtuzumab,
• Kev txhaj tshuaj Alemtuzumab tuaj yeem ua rau muaj kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:
• Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Kev txhaj tshuaj Alemtuzumab tuaj yeem ua rau mob hnyav lossis tuag taus rau lub cev muaj kabmob (mob uas cov kabmob tiv thaiv lub cev ua rau lub cev muaj mob thiab ua rau mob, o, thiab ua kom puas), suav nrog thrombocytopenia (muaj plasmaets tsawg [ib hom ntshav ntshav xav tau rau ntshav txhaws]) thiab teeb meem raum. Qhia koj tus kws kho mob yog tias koj muaj teeb meem los ntshav lossis mob raum. Yog tias koj muaj cov tsos mob li hais hauv qab no, hu rau koj tus kws kho mob tam sim ntawd: los ntshav txawv txav, o ntawm koj ob txhais ceg lossis ko taw, hnoos tau ntshav, los ntshav los ntawm qhov txiav uas nyuaj los cheem, hnyav los yog cev ntas los ntshav, pob ntawm koj cov tawv nqaij uas liab, paj yeeb, lossis ntshav, los ntshav los ntawm cov pos hniav lossis lub qhov ntswg, ntshav hauv cov zis, mob hauv siab, txo zis, thiab qaug zog.

Tej zaum koj yuav muaj qhov mob hnyav lossis ib qho txaus ntshai txoj sia vim tias koj txhaj tshuaj alemtuzumab txhaj tshuaj lossis ntev txog 3 hnub tom qab. Koj yuav tau txais txhua qhov tshuaj ntawm cov tshuaj hauv qhov chaw kho mob, thiab koj tus kws kho mob yuav saib xyuas koj zoo thaum lub sijhawm infusion thiab tom qab koj tau txais cov tshuaj. Nws yog ib qho tseem ceeb uas koj nyob ntawm qhov chaw infusion tsawg kawg 2 teev tom qab koj qhov kev ua tiav tiav. Yog tias koj pom muaj cov tsos mob hauv qab no thaum lub sijhawm lossis tom qab koj nqus dej, hais rau koj tus kws kho mob: kub taub hau; ua daus no; xeev siab; mob taub hau; ntuav; khaus; ua pob; khaus; dej ntws; kev mob siab; kiv taub hau; txog siav; ua pa nyuaj lossis nqos; ua pa qeeb; nruj ntawm caj pas; o ntawm lub qhov muag, ntsej muag, qhov ncauj, di ncauj, nplaig lossis caj pas; txhaws qa; kiv taub hau; lub teeb ci ntsa iab; tsaus muag; lub plawv dhia nrawm lossis ceev; lossis mob hauv siab.

Kev txhaj tshuaj Alemtuzumab tuaj yeem ua rau mob stroke lossis kua muag hauv koj cov hlab ntsha uas xa ntshav mus rau koj lub hlwb, tshwj xeeb hauv thawj 3 hnub tom qab kho tas. Yog tias koj muaj cov tsos mob nram qab no thaum lossis tom qab koj hla, koj qhia koj tus kws kho mob tam sim ntawd: poob rau ntawm ib sab ntawm lub ntsej muag, mob taub hau heev, mob caj dab, cia li tsis muaj zog los yog loog ntawm caj npab lossis txhais ceg, tshwj xeeb ntawm ib sab ntawm lub cev , lossis nyuaj hais lus, lossis nkag siab.

Kev txhaj tshuaj Alemtuzumab tuaj yeem ua rau muaj kev pheej hmoo ntxiv tias koj yuav muaj qee yam qog nqaij hlav, nrog rau mob qog nqaij hlav cancer, mob melanoma (hom mob qog nqaij hlav ntshav), thiab qee yam mob qog ntshav Koj yuav tsum kuaj koj daim tawv los ntawm tus kws kho mob kuaj pom muaj tus kabmob ua ntej koj pib kho thiab ib xyoos tom qab. Hu rau koj tus kws kho mob yog tias koj muaj cov tsos mob hauv qab no uas yuav yog qhov qhia pom ntawm qog nqaij hlav cancer: cov qog tshiab lossis o ntawm koj lub caj dab; mob pem hauv ntej caj dab; piav tsis hnyav poob; mob pob txha lossis mob pob txha; qog lossis o hauv koj cov tawv nqaij, caj dab, taub hau, puab tais lossis plab; kev hloov ntawm cov duab mole, loj, lossis xim lossis los ntshav; cov hlwv me me nrog cov ciam teb tsis xwm yeem thiab ntu uas pom liab, dawb, xiav lossis xiav-dub; txhaws qa lossis lwm lub suab pauv hloov uas tsis ploj; teeb meem nqos lossis ua pa; lossis hnoos.

Vim tias muaj kev pheej hmoo nrog cov tshuaj no, alemtuzumab txhaj tshuaj tsuas yog muaj los ntawm cov kev txwv tshwj xeeb txwv kev tsocai. Qhov kev zov me nyuam hu ua Qhov kev zov me nyuam hu ua Lemtrada Kev Ntsuam Xyuas Kev Phom Sij thiab Kev Ruaj Ntseg (REMS). Nug koj tus kws kho mob yog tias koj muaj lus nug txog yuav ua li cas koj yuav tau txais koj cov tshuaj.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee qhov kev kuaj mob los kuaj xyuas koj lub cev cov lus teb rau alemtuzumab txhaj tshuaj ua ntej thiab thaum kho koj tus mob thiab 4 xyoos tom qab koj tau txais koj cov tshuaj kawg.

Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev txhaj tshuaj alemtuzumab.

Alemtuzumab txhaj tshuaj yog siv los kho cov neeg laus nrog ntau yam mob sclerosis (MS; tus kabmob uas cov hlab ntsha tsis ua haujlwm zoo thiab tib neeg yuav muaj qhov tsis muaj zog, ua tsis taus pa, tsis tuaj yeem ua haujlwm rau cov leeg, thiab muaj teeb meem ntawm lub zeem muag, hais lus thiab zais zis) uas tsis zoo nrog tsawg dua ob lossis ntau dua MS tshuaj noj suav nrog:

• foos rov ua daim ntawv dua (hom mob uas cov tsos mob tshwm sim ib lub sijhawm) lossis
• theem ob hom foos (hom mob uas tus mob huam tuaj feem ntau).

Alemtuzumab nyob hauv chav kawm ntawm cov tshuaj hu ua monoclonal antibodies. Nws ua haujlwm los ntawm kev txo qis qhov kev txiav txim ntawm cov qe ntshav tsis muaj zog uas yuav ua rau lub paj hlwb tsis zoo.

Alemtuzumab tseem tseem muaj kev txhaj tshuaj (Campath) uas yog siv los kho tus mob lymphocytic rau cov leeg ntshav (mob qog nqaij hlav qeeb uas muaj ntau ntawm qee hom qe ntshav dawb nyob hauv lub cev). Cov duab no tsuas qhia txog kev txhaj tshuaj alemtuzumab (Lemtrada) rau ntau tus sclerosis. Yog tias koj tau txais alemtuzumab txog kev mob qog nqaij hlav ntev, nyeem cov duab muaj npe hu ua Alemtuzumab Txhaj Tshuaj (Mob Ntev Lymphocytic Leukemia).

Alemtuzumab kev txhaj tshuaj los ua kev daws teeb meem (ua kua) rau kev txhaj tshuaj rau ntshav (rau hauv cov leeg ntshav) ntau dua 4 teev los ntawm tus kws kho mob lossis kws kho mob hauv tsev kho mob lossis chaw haujlwm. Feem ntau nws muab ib zaug rau ib hnub rau 5 hnub rau thawj zaug. Ib ntu kev kho mob thib ob ib txwm muab ib hnub ib zaug rau 3 hnub, 12 hlis tom qab thawj zaug kev kho mob. Koj tus kws kho mob tuaj yeem sau lub voj voog kho ntxiv rau 3 hnub tsawg kawg 12 lub hlis tom qab kev kho mob dhau los.

Alemtuzumab txhaj tshuaj pab tswj hwm ntau tus sclerosis, tab sis nws tsis kho nws.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej tau txais kev txhaj tshuaj alemtuzumab,

• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau alemtuzumab, lwm yam tshuaj, lossis lwm yam tshuaj hauv alemtuzumab txhaj tshuaj. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov ntawv yuav tshuaj, cov vitamins, khoom noj khoom haus muaj txiaj ntsig zoo, koj noj lossis npaj yuav noj. Nco ntsoov hais cov hauv qab no: alemtuzumab (Campath; cov khoom lag luam muaj lub npe ntawm cov khoom siv los kho mob leukemia); cov tshuaj tua kabmob; lossis cov tshuaj tiv thaiv kab mob xws li cyclosporine (Gengraf, Neoral, Sandimmune), mycophenolate (Cellcept), prednisone, thiab tacrolimus (Astagraf, Envarsus, Prograf). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia rau koj tus kws kho mob yog tias koj muaj ib qho kev kis mob lossis tib neeg cov tshuaj tiv thaiv kab mob (HIV). Koj tus kws kho mob yuav qhia koj kom tsis txhob txhaj tshuaj alemtuzumab.
• qhia rau koj tus kws kho mob yog tias koj tau lossis muaj dua li mob ntsws (mob ntsws; mob hnyav uas cuam tshuam rau lub ntsws thiab qee zaum lwm qhov hauv lub cev), tus mob herpes zoster (mob pob khaus; ua pob rau hauv cov neeg uas tau mob qhua maj yav dhau los) , mob kas cees ntawm qhov chaw mob (tus kab mob pob sawv hlwv uas ua rau mob nyob ib puag ncig ntawm lub chaw mos thiab qhov quav ib zaug), varicella (mob qhua taum), mob siab daim siab nrog rau tus kab mob siab B lossis kab mob siab C, lossis lub qog, lub plawv, mob ntsws, lossis mob rau daim tawv.
• qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj yog poj niam, koj yuav tsum tau mus kuaj cev xeeb tub ua ntej koj pib kho thiab siv tshuaj tiv thaiv kom tsis muaj menyuam thaum lub sijhawm kho thiab 4 hlis tom qab koj qhov tshuaj kawg. Tham nrog koj tus kws kho mob txog hom kev tswj tsis pub muaj menyuam uas koj tuaj yeem siv los tiv thaiv kev xeeb tub nyob rau lub sijhawm no. Yog tias koj cev xeeb tub thaum koj tau txhaj tshuaj alemtuzumab, hu rau koj tus kws kho mob tam sim ntawd. Alemtuzumab tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab.
• Nug koj tus kws kho mob seb koj puas yuav tsum tau txhaj tshuaj tiv thaiv ua ntej koj tau txais alemtuzumab. Qhia rau koj tus kws kho mob yog tias koj tau txhaj tshuaj tiv thaiv nyob rau 6 lub hlis dhau los. Tsis txhob txhaj tshuaj tiv thaiv kab mob yam tsis tau nrog koj tus kws kho mob tham thaum kho koj.

Zam cov zaub mov hauv qab no uas tuaj yeem ua rau mob tsawg kawg yog 1 lub hlis ua ntej koj pib tau txais alemtuzumab thiab thaum kho koj: cov nqaij ntses, khoom noj siv mis ua nrog cov mis tsis tau, nqaij mos, lossis nqaij undercooked, nqaij ntses, lossis nqaij qaib.

Kev txhaj tshuaj Alemtuzumab tuaj yeem ua rau muaj kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• teeb meem pw tsaug zog lossis tsaug zog zoo
• mob hauv ceg, caj npab, ntiv taw, thiab tes
• sab nraub qaum, txha, lossis caj dab
• tingling, pricking, chilling, hlawv, lossis loog hloov ntawm daim tawv nqaij
• daim tawv liab, khaus, los yog daim tawv
• Kev mob siab
• o ntawm lub qhov ntswg thiab caj pas

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

• txog siav, ua pa hauv siab lossis nruj, hnoos, hnoos ntshav, lossis hawb pob
• kub taub hau, ua daus no, raws plab, xeev siab, ntuav, mob taub hau, mob pob qij txha los yog mob leeg, caj dab txhav, taug kev nyuaj, los sis lub siab hloov.
• doog ntshav los sis los ntshav tau yooj yim, ntshav tawm hauv cov zis lossis cov quav, qhov ntswg los ntshav, ntuav los ntshav, lossis mob thiab / lossis mob rau pob qij txha
• tawm hws ntau dhau, qhov muag o, poob phaus, ceeb, lossis plawv dhia ceev
• piav tsis hnyav ntxiv, nkees, hnov ​​txias, los yog cem quav
• kev nyuaj siab
• xav txog kev ua phem lossis tua tus kheej tuag lossis npaj lossis sim ua
• qhov chaw mos mob, qhov xav tau ntawm koob thiab koob, lossis ua pob rau ntawm chaw mos lossis hauv qhov chaw mos
• qhov ncauj tawm los yog mob ua npaws ntawm los yog ib ncig ntawm lub qhov ncauj
• mob pob khaus ntawm ib sab ntawm lub ntsej muag lossis lub cev, nrog hlwv, mob, khaus, lossis ua pob rau thaj chaw
• (rau cov poj niam) qhov quav ntawm lub paum, dawb lossis daj ua paum ntawm qhov chaw mos (tej zaum yuav zoo li pob los sis zoo li hauv tsev me), los yog khaus qhov chaw mos
• dawb txhab ntawm tus nplaig lossis sab plhu puab
• mob plab lossis rhiab, ua npaws, xeev ntuav, lossis ntuav
• xeev siab, ntuav, mob plab, nkees heev, tsis qab los, daj ntseg lossis tawv nqaij, nkees nkees heev, tso zis dub, lossis tso ntshav tawm los yog doog yooj yim dua li ib txwm
• kev ua kom tsis muaj zog ntawm ib sab ntawm lub cev uas zuj zus nyob hauv lub sijhawm; clumsiness ntawm caj npab los yog txhais ceg; cov kev hloov hauv koj txoj kev xav, kev nco, taug kev, tshuav nyiaj li cas, hais lus, pom kev, lossis lub zog uas kav mus ob peb hnub; mob taub hau; qaug dab peg; tsis meej pem; lossis tus kheej hloov
• kub taub hau, cov qog o, xoo pob liab vog, qaug dab peg, hloov ntawm kev xav lossis ceev faj, lossis tshiab lossis ua tsis zoo txaus ntseeg lossis taug kev nyuaj

Kev txhaj tshuaj Alemtuzumab tuaj yeem ua rau muaj kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum tau txais cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

• mob taub hau
• ua pob
• kiv taub hau

Nug koj tus kws muag tshuaj yog tias koj muaj lus dab tsi txog kev txhaj tshuaj alemtuzumab.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Lemtrada^®