Pembrolizumab Txhaj Tshuaj

Zoo Siab

• Kev txhaj tshuaj Pembrolizumab yog siv: Pembrolizumab txhaj tshuaj yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua monoclonal tiv thaiv kab mob. Nws ua haujlwm los ntawm kev pab koj lub cev tiv thaiv kabmob ua rau qeeb lossis nres kev loj hlob ntawm cov qog nqaij hlav cancer.
• Ua ntej tau txais kev txhaj tshuaj pembrolizumab,
• Pembrolizumab txhaj tshuaj tuaj yeem tsim cov kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:

Kev txhaj tshuaj Pembrolizumab yog siv: Pembrolizumab txhaj tshuaj yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua monoclonal tiv thaiv kab mob. Nws ua haujlwm los ntawm kev pab koj lub cev tiv thaiv kabmob ua rau qeeb lossis nres kev loj hlob ntawm cov qog nqaij hlav cancer.

• los kho tus mob melanoma (hom mob qog nqaij daim tawv) uas tsis tuaj yeem raug kho nrog kev phais mob lossis tau kis mus rau lwm qhov ntawm lub cev, lossis ua ke nrog lwm cov tshuaj kho mob los kho thiab tiv thaiv kom rov qab mob melanoma tom qab kev phais nws tshem tawm thiab ib qho kev cuam tshuam lymph. nodes;
• los kho qee yam mob uas tsis yog-me-hlwb mob ntsws (NSCLC) uas tsis tuaj yeem siv rau kev phais mob, lwm yam tshuaj kho mob, lossis kev kho hluav taws xob lossis uas tau kis mus rau lwm qhov ntawm lub cev lossis mob hnyav thaum lossis tom qab nws raug kho nrog platinum muaj kev siv tshuaj kho mob (cisplatin, carboplatin), lossis kev sib txuas nrog lwm cov tshuaj kho mob (paclitaxel, pemetrexed) los kho qee yam ntawm NSCLC uas tau kis mus rau lwm qhov ntawm lub cev;
• txhawm rau kho qee yam mob taub hau thiab caj dab uas rov qab los lossis kis mus rau lwm qhov ntawm lub cev thiab tsis tuaj yeem raug tshem tawm los ntawm kev phais mob. Nws kuj tseem tuaj yeem siv ua ke nrog fluorouracil thiab ib lub platinum uas muaj cov tshuaj kho mob (cisplatin, carboplatin) los kho qee yam mob qog taub hau thiab caj dab uas rov qab los lossis kis mus rau lwm qhov ntawm lub cev thiab tsis tuaj yeem kho nrog kev phais mob. Pembrolizumab tseem tseem siv coj los kho qee yam mob taub hau thiab caj dab uas tau ua kom tsis zoo lossis kis mus rau lwm qhov ntawm lub cev thaum lub sijhawm lossis tom qab siv tshuaj kho mob;
• txhawm rau kho qee yam Hodgkin's mob cancer (Hodgkin's disease) hauv cov menyuam yaus thiab cov neeg laus tsis tau zoo dua nrog lwm cov kev siv tshuaj kho mob lossis tau zoo dua tab sis tau rov qab los kho nrog lwm cov tshuaj kho mob thiab hauv menyuam yaus tom qab tau kho ob lossis ntau zaus nrog lwm cov tshuaj kho mob ;
• txhawm rau kho qee yam ntawm mediastinal B-cell lymphoma (PMBCL; tsis-Hodgkin lymphoma) hauv cov menyuam yaus thiab cov neeg laus tsis tau zoo dua nrog lwm cov kev siv tshuaj kho mob lossis rov qab los tom qab tau kho ob lossis ntau zaus nrog lwm cov tshuaj kho mob;
• txhawm rau kho qee yam mob cancer urothelial (mob cancer rau lub zais zis thiab lwm qhov ntawm lub zais zis) uas tau kis mus rau cov ntaub so ntswg nyob ze lossis lwm qhov hauv lub cev hauv cov neeg uas tsis tuaj yeem tau txais platinum muaj cov tshuaj kho mob (cisplatin, carboplatin) , lossis tus kabmob twg hajyam mob loj ntxiv rau lub sijhawm lossis tomqab nws kho cov tshuaj khomob no;
• txhawm rau kho qee yam mob zais zis hauv cov neeg tsis tau zoo dua nrog lwm cov tshuaj (Bacillus Calmette-Guerin; BCG txoj kev kho) thiab tus uas tsis tuaj yeem lossis leej twg txiav txim siab tsis raug kho los ntawm kev phais mob kom tshem tawm lub zais zis;
• los kho qee yam mob khees-xaws mob hnyuv (mob cancer uas pib ua rau lub plab hnyuv loj) thiab qee yam mob qog ua thawj txoj kev kho mob rau menyuam yaus thiab cov neeg laus uas tsis tuaj yeem kho los ntawm kev phais mob lossis uas kis mus rau lwm qhov ntawm lub cev lossis hauv cov uas worsened tom qab nws tau kho nrog lwm cov tshuaj kho mob;
• txhawm rau kho qee yam mob cancer (mob plab) lossis mob qog nqaij hlav hauv thaj chaw uas lub plab ntsib txoj hlab pas (lub raj ntawm caj pas thiab lub plab) uas tau rov qab los lossis uas tau kis mus rau lwm qhov ntawm lub cev thaum lossis tom qab 2 lossis ntau dua kev siv tshuaj kho mob;
• los kho qee yam mob qog noj ntshav uas tau rov qab los thiab tau kis mus rau cov ntaub so ntswg ze lossis lwm qhov ntawm lub cev tom qab kho nrog ib lossis ntau dua lwm cov tshuaj kho mob thiab tsis tuaj yeem raug kho nrog kev phais mob lossis hluav taws xob;
• txhawm rau kho qee yam mob khees-xaws ncauj tsev menyuam (mob qog nqaij hlav uas pib qhib lub tsev menyuam [lub tsev menyuam]) uas tau rov qab los lossis tau kis mus rau lwm qhov ntawm lub cev thaum lossis tom qab kho nrog lwm cov tshuaj kho mob;
• los kho qee hom mob hepatocellular carcinoma (HCC; ib hom mob cancer mob siab) hauv cov neeg uas tau kho yav tas los ua tsis tiav nrog sorafenib (Nexafar);
• kho Merkel cell carcinoma (MCC; ib hom mob cancer ntawm daim tawv nqaij) hauv cov menyuam yaus thiab cov neeg laus uas tau rov qab los thiab kis mus rau cov ntaub so ntswg ze lossis lwm qhov ntawm lub cev;
• nyob rau hauv kev sib xyaw nrog axitinib (Inlyta) los kho cov kab mob hauv lub raum pob txha mos (RCC; ib hom mob qog nqaij hlav uas pib hauv lub raum);
• sib xyaw nrog lenvatinib (Lenvima) txhawm rau kho qee yam mob cancer ntawm endometrium (meem hauv tsev menyuam) uas tau kis mus rau lwm qhov ntawm lub cev lossis mob hnyav thaum lossis tom qab siv tshuaj kho mob lossis tsis tuaj yeem kho nrog kev phais mob lossis hluav taws xob. kev kho mob;
• los kho qee yam mob qog uas kis mus rau lwm qhov ntawm lub cev lossis tsis tuaj yeem kho los ntawm kev phais mob rau cov neeg laus thiab cov menyuam yaus uas yav tas los kho tsis ua tiav nrog lwm cov tshuaj kho mob thiab tsis muaj lwm txoj kev kho mob txaus siab;
• los kho qee yam mob qog nqaij hlav ntxhiab cell (carcinoma cell mob cancer) uas tau rov qab los yog kis mus rau lwm qhov ntawm lub cev thiab tsis tuaj yeem raug kho nrog kev phais mob lossis hluav taws xob kho;
• thiab ua ke nrog kev siv tshuaj kho mob los kho qee yam mob qog noj ntshav mis uas tau rov qab los rau cov ntaub so ntswg nyob ze lossis tau kis mus rau lwm qhov ntawm lub cev thiab tsis tuaj yeem kho nrog kev phais mob.

Pembrolizumab txhaj tshuaj tuaj ua hmoov los ntawm cov kua thiab txhaj rau ntshav (dhau rau hauv cov leeg ntshav) ntev dua 30 feeb los ntawm tus kws kho mob lossis kws kho mob hauv tsev kho mob lossis chaw kho mob. Feem ntau nws ib txwm txhaj ib zaug nyob rau txhua 3 lossis 6 lub lim tiam kom ntev li ntev tau yog koj tus kws kho mob pom zoo kom koj tau txais kev kho mob.

Pembrolizumab txhaj tshuaj tuaj yeem ua rau muaj kev tsis haum thaum lub sijhawm, lossis tsis ntev tom qab ua ntej txoj kev noj tshuaj. Yog koj pom muaj cov tsos mob li hais hauv qab no, qhia rau koj tus kws kho mob tam sim ntawd: ua npaws, ua npaws, ua daus no, tshee tshee, kiv taub hau, zoo li tsaus muag, ua pa luv, ua pa nyuaj, khaus, ua pob liab vog lossis khaus.

Koj tus kws kho mob tuaj yeem ncua lossis txiav koj txoj kev kho mob nrog pembrolizumab txhaj tshuaj, lossis kho koj nrog kev siv tshuaj ntxiv, nyob ntawm koj cov lus teb rau cov tshuaj thiab cov kev mob tshwm sim uas koj muaj. Tham nrog koj tus kws kho mob txog saib koj xav li cas thaum kho koj tus mob.

Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia cov neeg mob rau koj (Siv Tshuaj Kho Mob) thaum koj pib kho nrog pembrolizumab txhaj tshuaj thiab txhua zaus koj tau txais koob tshuaj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib tau Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) lub vev xaib (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) lossis cov chaw tsim tshuaj paus lub vev xaib kom tau txais Kev Qhia Tshuaj.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej tau txais kev txhaj tshuaj pembrolizumab,

• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau pembrolizumab, lwm yam tshuaj noj, lossis ib qho twg hauv cov tshuaj txhaj pembrolizumab. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia rau koj tus kws kho mob yog tias koj tau muaj kev hloov khoom nruab nrog lossis hloov hlwb pob txha thiab yog tias koj muaj lossis tau muaj kev kho mob hluav taws xob ntau rau koj lub hauv siab; ib qho kab mob autoimmune (kev mob lub cev ua rau lub cev tiv thaiv tsis muaj mob ntawm lub cev) xws li Crohn's mob (mob uas lub cev tiv thaiv kab mob hauv lub plab ua rau mob plab, raws plab, poob phaus, thiab kub ib ce), mob plab mob (mob uas ua rau o thiab mob rau hauv txoj hnyuv [txoj hnyuv loj] thiab lub qhov quav), lossis lupus (mob uas lub nruab nrog cev tawm tsam ntau cov ntaub so ntswg thiab cov kabmob nrog rau daim tawv nqaij, pob qij txha, ntshav, thiab raum); ntshav qab zib; cov thyroid teeb meem; ib yam kab mob ntsws lossis ua pa nyuaj; lossis lub raum lossis mob rau daim siab.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Koj yuav tsum tau coj mus kuaj cev xeeb tub ua ntej pib kev kho mob. Koj yuav tsum tsis txhob cev xeeb tub thaum koj tau txais kev txhaj tshuaj pembrolizumab thiab rau 4 lub hlis tom qab koj zaum kawg. Tham nrog koj tus kws kho mob txog kev tiv thaiv kev xeeb tub uas yuav ua haujlwm rau koj. Yog tias koj xeeb tub thaum tau txais kev txhaj tshuaj pembrolizumab, hu rau koj tus kws kho mob tam sim ntawd. Kev txhaj tshuaj Pembrolizumab tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab.
• qhia rau koj tus kws kho mob yog tias koj pub mis niam lossis npaj yuav pub mis. Koj tus kws kho mob yuav qhia koj kom tsis txhob pub mis niam thaum tau txais pembrolizumab txhaj, thiab rau 4 lub hlis tom qab koj koob zaum kawg.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Pembrolizumab txhaj tshuaj tuaj yeem tsim cov kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• txha los nraub qaum mob
• o ntawm lub cev lossis lub ntsej muag
• hloov xim tawv nqaij
• nkees heev lossis tsis muaj lub zog
• ua npaws
• xeev siab
• ntuav

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:

• hlwv lossis tev tawv nqaij; daim tawv nqaij liab; ua pob; lossis khaus
• qhov ncauj tawm los yog mob hauv qhov ncauj, qhov ntswg, caj pas, lossis ntawm qhov chaw mos
• txog siav
• mob hauv siab
• tshiab lossis txhawm rau hnoos
• zawv plab
• cov quav uas dub, tarry, nplaum, lossis muaj ntshav lossis hnoos qeev
• mob plab heev
• xeev siab thiab ntuav
• nce lossis txo qhov qab los noj mov
• nce nqhis dej
• mob hauv sab saud hauv plab
• daj ntawm daim tawv nqaij lossis qhov muag
• yooj yim los ntshav los yog doog ntshav
• lub plawv dhia ceev
• hloov hauv qhov hnyav (nce lossis poob)
• plaub hau poob
• nce hws
• hnov txias
• tob hauv lub suab lossis txhaws qa
• o rau pem hauv ntej ntawm caj dab (goiter)
• tingling thiab tsis muaj zog nyob hauv taw, ceg, tes, thiab caj npab
• mob taub hau heev los sis pheej mob, mob ib ce
• mob leeg tsis muaj zog
• kiv taub hau lossis tsaus ntais
• tsaus muag
• hloov ntshav lossis xim tso zis
• mob los yog mob ncus thaum tso zis
• ntshav hauv zis
• kev hloov pauv ntawm lub zeem muag
• zoo li tsis meej pem

Pembrolizumab txhaj tshuaj tuaj yeem ua lwm cov phiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum tau txais cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee qhov kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau kev txhaj tshuaj pembrolizumab. Rau qee qhov xwm txheej, koj tus kws kho mob yuav hais kom kuaj ntshav kuaj ua ntej koj pib kho mob seb koj puas tuaj yeem kho tau mob pembrolizumab.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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