Tus Sau: William Ramirez
Hnub Kev Tsim: 19 Lub Cuaj Hli Ntuj 2021
Hloov Hnub: 1 Lub Kaum Ib Hli Ntuj 2024
Anonim
Dasatinib in the Second-Line Setting
Daim Duab: Dasatinib in the Second-Line Setting

Zoo Siab

Dasatinib yog siv los kho qee yam mob myeloid leukemia (CML; ib hom mob qog noj ntshav dawb) yog thawj txoj kev kho mob thiab hauv cov neeg uas tsis tuaj yeem tau txais txiaj ntsig los ntawm lwm cov tshuaj tiv thaiv kab mob suav nrog rau imatinib (Gleevec) lossis hauv cov neeg uas tsis tuaj yeem noj cov tshuaj no vim tias muaj kev phiv. Dasatinib tseem tseem siv coj los kho qee hom mob ntsws ntev CML hauv menyuam yaus. Dasatinib tseem tseem siv coj los kho qee yam mob ntsig txog cov mob qog ua ntshav (TXHUA; ib hom mob cancer ntshav dawb) hauv cov neeg tsis tuaj yeem tau txais txiaj ntsig los ntawm lwm cov tshuaj tiv thaiv kab mob ntshav lossis cov uas tsis tuaj yeem noj cov tshuaj no vim tias muaj kev phiv. Dasatinib yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua kinase inhibitors. Nws ua haujlwm los ntawm kev thaiv qhov kev txiav txim ntawm cov protein tsis txaus uas ua rau muaj hlwb hlav hlav. Qhov no yuav pab kom tsis txhob kis mob hlwb.

Dasatinib los ua ib ntsiav tshuaj noj ntawm qhov ncauj. Feem ntau nws yuav noj ib hnub, thaum sawv ntxov lossis yav tsaus ntuj, nrog lossis tsis tau noj mov. Noj dasatinib nyob ib ncig ntawm tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj dasatinib raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.


Nqos cov ntsiav tshuaj tag nrho; tsis txhob sib faib, zom, lossis tsoo lawv. Hnav cov hnab looj tes latex lossis nitrile thaum tuav cov ntsiav tshuaj uas huam yuaj lossis tawg kom tiv thaiv kev sib cuag nrog cov tshuaj.

Koj tus kws kho mob tuaj yeem hloov kho koj qhov kev noj tshuaj lossis txwv tsis pub kho koj cov tshuaj dasatinib raws li koj cov lus teb rau kev kho thiab txhua yam kev mob tshwm sim uas koj tau ntsib dua. Tham nrog koj tus kws kho mob txog saib koj xav li cas thaum kho koj tus mob. Txuas ntxiv noj cov tshuaj dasatinib txawm hais tias koj tus kheej zoo. Tsis txhob tsum noj dasatinib yam tsis tham nrog koj tus kws kho mob.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj dasatinib,

  • qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau dasatinib, lwm yam tshuaj noj, lossis lwm yam tshuaj hauv dasatinib ntsiav tshuaj. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob sau tseg thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, thiab cov khoom noj zoo uas koj noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: anticoagulants ('' ntshav thinners '') xws li warfarin (Coumadin, Jantoven); anthracycline tshuaj rau mob qog noj ntshav xws li daunorubicin (Cerubidine), doxorubicin (Doxil), thiab epirubicin (Ellence); tej yam tshuaj tua kab mob xws li ketoconazole (Nizoral), itraconazole (Onmel, Sporanox), thiab voriconazole (Vfend); clarithromycin (Biaxin, hauv PrevPac); dexamethasone; qee cov tshuaj siv los kho tib neeg cov tshuaj tiv thaiv kab mob (HIV) xws li atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), thiab saquinavir (Invirase); qee cov tshuaj noj rau lub plawv dhia tsis xws li amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), mexiletine (Mexitil), procainamide, propafenone (Rythmol), quinidine (hauv Nued) Betapace, Betapace AF, Sorine), tshuaj noj kom txo tau cov plab kua qaub xws li cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ranitidine (Zantac), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), thiab rabeprazole (AcipHex); nefazodone; phom phom (Rimactane, Rifadin, hauv Rifater, hauv Rifamate); thiab telithromycin (Ketek); Ntau lwm yam tshuaj kuj tseem tuaj yeem cuam tshuam nrog dasatinib, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • yog tias koj noj tshuaj tiv thaiv kab mob, xws li aluminium hydroxide / magnesium hydroxide (Maalox), calcium carbonate (Tums), lossis calcium carbonate thiab magnesium (Rolaids), noj lawv 2 teev ua ntej lossis 2 teev tom qab koj noj dasatinib.
  • qhia koj tus kws kho mob tias yam tshuaj ntsuab koj noj, tshwj xeeb tshaj yog St. John wort.
  • qhia rau koj tus kws kho mob yog tias koj muaj lossis tau muaj lactose tsis txaus (tsis muaj peev xwm zom cov khoom noj siv mis), muaj cov poov tshuaj lossis magnesium ntau hauv koj cov ntshav, QT syndrome ntev (mob plawv uas yuav ua rau kiv taub hau, tsaus muag, lossis lub plawv dhia tsis xwm yeem), teeb meem nrog koj muaj zog tiv thaiv kab mob, lossis mob siab, mob ntsws, lossis mob plawv.
  • qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Koj yuav tsum tsis txhob cev xeeb tub thaum koj noj dasatinib thiab rau 30 hnub tom qab koj zaum kawg. Tham nrog koj tus kws kho mob txog kev tiv thaiv kev xeeb tub uas yuav ua haujlwm rau koj. Yog tias koj cev xeeb tub thaum noj dasatinib, hu rau koj tus kws kho mob. Cov poj niam cev xeeb tub yuav tsum tsis txhob kov cov ntsiav tshuaj dasatinib tawg lossis tawg. Dasatinib tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab.
  • tsis txhob pub mis thaum noj dasatinib thiab rau 2 lub lis piam tom qab koj cov tshuaj kawg.
  • koj yuav tsum paub tias cov tshuaj no tuaj yeem txo qis kev muaj menyuam hauv txivneej thiab pojniam. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev noj dasatinib.
  • yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav uas koj noj dasatinib.

Tsis txhob noj txiv kab ntxwv qaub lossis haus cov txiv kab ntxwv kua txiv thaum noj cov tshuaj no.


Hla lub tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Dasatinib yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • mob leeg
  • tsis muaj zog
  • mob tej pob txha
  • mob, kub hnyiab lossis nyhav rau hauv txhais tes lossis taw
  • ua pob
  • daim tawv nqaij liab
  • tev tawv nqaij
  • o, liab thiab mob hauv lub qhov ncauj
  • qhov ncauj tawm
  • zawv plab
  • xeev siab
  • ntuav
  • cem quav
  • mob plab los yog o
  • tsis qab los noj mov
  • poob phaus

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:

  • kub taub hau, mob caj pas, ua daus no, thiab / lossis lwm yam cim ntawm kis
  • o ntawm lub qhov muag, tes, caj npab, taw, pob taws, lossis ceg qis
  • nce ceeb thawj sai
  • ua pa nyuaj, tshwj xeeb tshaj yog thaum pw
  • hnoos tau paj yeeb lossis ntshav tawm
  • hnoos qhuav
  • mob hauv siab uas mob heev ntxiv thaum hnoos, txham, lossis ua pa tob tob
  • lub hauv siab ceev
  • kiv taub hau
  • tsaus muag
  • lub plawv dhia ceev ceev, tsis meej, los yog sib tsoo
  • mob taub hau
  • nkees nkees
  • tsis meej pem
  • Kev pub mis ib ntus (hauv cov menyuam yaus)
  • doog ntshav los ntshav tsis txawv
  • dub thiab tarry quav
  • liab ntshav hauv cov quav
  • ntshav ntuav
  • ntuav cov khoom uas zoo li kas fes kas fes
  • maj lossis hais lus nyuaj
  • tsis muaj zog lossis loog ntawm ib sab caj npab lossis txhais ceg

Dasatinib tuaj yeem ua rau qeeb hlob lossis pob txha mob rau menyuam yaus. Koj tus menyuam tus kws kho mob yuav soj qab xyuas koj tus menyuam txoj kev txhim kho kom zoo thaum nws noj dasatinib. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm qhov muab cov tshuaj no rau koj tus menyuam.


Dasatinib tuaj yeem ua lwm yam phiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

  • doog ntshav los ntshav tsis txawv
  • kub taub hau, mob caj pas, ua daus no, thiab / lossis lwm yam cim ntawm kis
  • txog siav
  • lub plawv dhia ceev
  • mob taub hau
  • daj ntseg tawv nqaij
  • tsis meej pem
  • nkees nkees

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj sim ua ntej thiab thaum kho koj lub cev kom kuaj xyuas koj lub cev cov lus teb rau dasatinib.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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Kawg Kho - 01/15/2018

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