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How does sitagliptin work? DPP-4 inhibitors and GLP-1 mimetics
Daim Duab: How does sitagliptin work? DPP-4 inhibitors and GLP-1 mimetics

Zoo Siab

Sitagliptin siv nrog rau kev noj haus thiab kev tawm dag zog thiab qee zaum nrog lwm cov tshuaj kom txo qis ntshav qab zib hauv cov neeg muaj ntshav qab zib hom 2 (mob uas ntshav qab zib siab dhau vim tias lub cev tsis tsim lossis siv insulin ib txwm). Sitagliptin nyob hauv chav kawm ntawm cov tshuaj hu ua dipeptidyl peptidase-4 (DPP-4) inhibitors. Nws ua haujlwm los ntawm kev nce qee yam khoom hauv ntuj uas txo cov ntshav qab zib thaum nws siab. Sitagliptin tsis raug siv los kho ntshav qab zib hom 1 (mob uas lub cev tsis tsim cov tshuaj insulin thiab yog li tsis tuaj yeem tswj cov piam thaj hauv ntshav).

Sij hawm dhau mus, cov neeg muaj ntshav qab zib thiab ntshav qab zib yuav tsim teeb meem loj lossis txaus ntshai rau lub neej, nrog rau kev mob plawv, mob hlab ntsha tawg, raum teeb meem, puas hlab ntshav, thiab teeb meem qhov muag. Noj tshuaj, hloov kev ua neej (xws li kev noj haus, kev tawm dag zog, txiav kev haus luam yeeb), thiab kev tshuaj xyuas koj cov piam thaj hauv ntshav tas li yuav pab tswj koj cov ntshav qab zib thiab txhim kho koj kev noj qab haus huv. Qhov kev kho no tseem yuav ua rau koj muaj feem yuav muaj mob plawv, mob stroke, lossis lwm yam mob ntsig txog ntshav qab zib xws li lub raum tsis ua hauj lwm, mob hlab hlwb (loog, ceg txias lossis txhais taw; txo qis kev sib deev hauv txiv neej thiab poj niam), teeb meem qhov muag, suav nrog kev hloov pauv los sis tsis pom kev, lossis pos hniav mob. Koj tus kws kho mob thiab lwm tus kws saib xyuas kev noj qab haus huv yuav tham nrog koj txog txoj kev zoo tshaj plaws los tswj koj cov ntshav qab zib.


Sitagliptin los ua ib ntsiav tshuaj los noj ntawm qhov ncauj. Nws feem ntau yog noj ib zaug ib hnub nrog lossis tsis muaj zaub mov. Siv sitagliptin nyob rau tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj sitagliptin raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Sitagliptin pab tswj cov ntshav qab zib kom ntshav tab sis tsis kho ntshav qab zib. Txuas ntxiv noj cov tshuaj sitagliptin txawm hais tias koj tus kheej yuav xis nyob. Tsis txhob tsum tsis txhob noj cov tshuaj sitagliptin yam tsis tau tham nrog koj tus kws kho mob.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj cov sitagliptin,

  • qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj ua xua ntawm sitagliptin lossis lwm yam tshuaj noj.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib yam ntawm cov hauv qab no: digoxin (Lanoxicaps, Lanoxin); tshuaj insulin; thiab qee cov tshuaj noj rau qhov mob ntshav qab zib nrog rau cov tshuaj acetohexamide, chlorpropamide (Diabinese), glimepiride (Amaryl), glipizide (Glucotrol, hauv Metaglip), glyburide (Diabeta, Glycron, Micronase), tolazamide (Tolinase), thiab tolbutamide. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • qhia rau koj tus kws kho mob yog tias koj haus dej haus cawv lossis haus dej haus cawv ntau dhau lawm thiab yog tias koj tau lossis tau muaj ntshav qab zib ketoacidosis (mob hnyav uas yuav tshwm sim thaum cov ntshav qab zib ntau dhau), mob pancreatitis (o ntawm qab thiav), mob qa, mob siab theem ntawm triglycerides (rog rog) hauv koj cov ntshav, lub plawv tsis ua hauj lwm, lossis lub raum mob.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj cov tshuaj sitagliptin, hu rau koj tus kws kho mob.
  • yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav tias koj noj sitagliptin.
  • tham nrog koj tus kws kho mob txog yam koj yuav tsum ua yog tias koj raug mob lossis yog tias koj ua npaws lossis kis kab mob. Cov mob no yuav cuam tshuam koj cov ntshav qab zib.
  • tham nrog koj tus kws kho mob txog cov tsos mob ntawm ntshav qab zib thiab ntshav qab zib thiab lwm yam mob ntshav qab zib, yuav ua li cas yog tias koj muaj cov tsos mob no, thiab yuav tiv thaiv cov mob no li cas.

Nco ntsoov ua raws li tag nrho cov zaub mov noj thiab kev tawm dag zog uas koj tus kws kho mob lossis kws ntsuas noj zaub mov xav kom ua.


Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Sitagliptin tuaj yeem tsim kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • txhaws ntswg los ntswg
  • mob caj pas
  • mob taub hau
  • zawv plab
  • xeev siab

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, tsum tsis txhob noj cov tshuaj sitagliptin thiab hu rau koj tus kws kho mob tam sim ntawd:

  • kub taub hau, xeev siab, ntuav, tsis qab los noj mov, mob txuas ntxiv uas pib ntawm sab sauv sab hauv lossis nruab nrab ntawm lub plab tab sis tuaj yeem kis rau sab nraub qaum
  • txog siav ua pa, nce phaus ceev ceev, lossis o ntawm taw lossis pob taws
  • khaus tawv, tawv nqaij sawv hlwv lossis tev tawm
  • mob tej pob txha
  • ua pob
  • khaus
  • o ntawm lub ntsej muag, daim di ncauj, nplaig, thiab caj pas
  • teeb meem ua pa lossis nqos

Sitagliptin tuaj yeem tsim kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.


Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob tuaj yeem xaj yam kev sim ua ntej thiab thaum kho koj nrog sitagliptin. Koj cov piam thaj hauv ntshav thiab glycosylated hemoglobin (HbA1c) yuav tsum kuaj xyuas kom tsis tu ncua los txiav txim koj cov lus teb rau sitagliptin. Koj tus kws kho mob tseem yuav qhia koj txog kev txheeb xyuas koj cov lus teb rau sitagliptin li cas los ntawm kev ntsuas koj cov ntshav lossis ntshav qab zib kom ntshav nyob hauv tsev. Ua raws li cov lus qhia no kom zoo.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Januvia®
  • Janumet® (uas muaj Metformin, Sitagliptin)
  • Juvisync® (muaj Simvastatin, Sitagliptin)
  • Steglujan® (muaj Ertugliflozin, Sitagliptin)

Cov khoom muaj npe khoom no tsis nyob rau ntawm kev ua lag luam. Muaj lwm cov kev xaiv uas siv tau.

Kawg Kho - 02/15/2021

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