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Zoledronic Acid Txhaj Tshuaj - Tshuaj Kho Mob
Zoledronic Acid Txhaj Tshuaj - Tshuaj Kho Mob

Zoo Siab

Zoledronic acid (Reclast) yog siv los tiv thaiv lossis kho osteoporosis (mob uas cov pob txha nyias thiab tsis muaj zog thiab tawg yooj yim) rau cov poj niam uas muaj hnub lawm ('hloov lub neej,' xaus kev coj khaub ncaws tsis tu ncua). Zoledronic acid (Reclast) kuj tseem siv los kho pob txha caj qaum hauv cov txiv neej, thiab tiv thaiv kab mob txha caj qaum hauv cov txiv neej thiab poj niam uas tab tom noj glucocorticoids (ib hom tshuaj corticosteroid uas tuaj yeem ua rau txha osteoporosis). Zoledronic acid (Reclast) kuj tseem siv los kho Paget's kab mob ntawm pob txha (ib qho mob uas cov pob txha mos thiab tsis muaj zog thiab yuav ua rau deformed, mob, lossis yooj yim tawg). Zoledronic acid (Zometa) yog siv los kho cov tshuaj calcium ntau ntxiv hauv cov ntshav uas yuav ua rau qee yam mob qog ntshav. Zoledronic acid (Zometa) kuj tseem siv nrog kev kho mob qog nqaij hlav cancer los kho cov pob txha los ntawm ntau yam mob myeloma [mob cancer uas pib hauv cov ntshav ntshav (cov qe ntshav dawb uas tsim cov tshuaj uas xav tau los tua kab mob)] lossis los ntawm kev mob qog ntshav uas pib nyob rau lwm qhov. lub cev tab sis tau kis mus rau cov pob txha. Zoledronic acid (Zometa) tsis yog kev kho mob qog nqaij hlav cancer, thiab nws yuav tsis qeeb lossis txwv tsis pub kis mob cancer. Txawm li cas los xij, nws siv tau los kho cov pob txha mob hauv cov neeg mob uas muaj mob qog noj ntshav. Zoledronic acid yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua bisphosphonates. Nws ua haujlwm los ntawm kev maj mam rhuav cov pob txha, nce pob txha cov pob txha (tuab), thiab txo cov calcium uas tso tawm hauv cov pob txha mus rau hauv cov ntshav.


Zoledronic acid tuaj ua kua (kua) los txhaj rau txoj leeg ntev li 15 feeb. Nws ib txwm txhaj tshuaj los ntawm tus kws kho mob hauv chaw kho mob lub chaw haujlwm, tsev kho mob, lossis chaw kho mob. Thaum zoledronic acid txhaj tshuaj yog siv los kho ntshav siab los ntawm cov calcium los ntawm mob cancer feem ntau yog muab ua ib koob nkaus xwb. Qhov koob thib ob yuav muab tau tsawg kawg 7 hnub tom qab txhaj tshuaj thawj zaug yog tias cov calcium calcium tsis poob rau theem ib txwm muaj lossis tsis cia nyob hauv theem li qub. Thaum zoledronic acid txhaj tshuaj yog siv los kho pob txha raug mob los ntawm ntau tus mob myeloma lossis mob qog nqaij hlav uas tau kis mus rau cov pob txha, feem ntau yog muab ib zaug txhua 3 rau 4 asthiv. Thaum zoledronic acid txhaj tshuaj yog siv los kho cov mob txha caj qaum hauv cov poj niam uas tau mob hauv lub cev, lossis hauv tus txiv neej, lossis los kho lossis tiv thaiv txha txha hniav laus hauv cov neeg uas tau noj glucocorticoids, feem ntau yog muab ib xyoos ib zaug. Thaum zoledronic acid siv los tiv thaiv pob txha mos nyob hauv cov poj niam uas tau muaj lub cev ntuag ntshav, feem ntau yog muab ib zaug nyob rau txhua 2 xyoo. Thaum zoledronic acid siv los kho Paget's kab mob ntawm pob txha, feem ntau yog muab ib koob tshuaj xwb, tab sis ntxiv cov koob tshuaj tom qab muab qee lub sijhawm dhau los.


Nco ntsoov tias haus tsawg kawg 2 khob dej lossis lwm yam kua hauv ob peb teev ua ntej koj tau txais zoledronic acid.

Koj tus kws kho mob yuav sau ntawv tawm tswv yim lossis qhia kom noj tshuaj ntxiv calcium thiab multivitamin uas muaj cov tshuaj vitamin D los noj thaum kho koj. Koj yuav tsum noj cov tshuaj no txhua hnub raws li koj tus kws kho mob tau qhia. Qhia rau koj tus kws kho mob yog tias muaj lub laj thawj uas koj yuav tsis tuaj yeem noj cov tshuaj no thaum kho koj tus mob.

Koj yuav hnov ​​cov tshuaj tiv thaiv nyob rau thawj ob peb hnub tom qab koj tau txais kev txhaj tshuaj zoledronic acid txhaj tshuaj. Cov tsos mob ntawm cov tshuaj tiv thaiv no tuaj yeem suav cov tsos mob ua npaws, ua npaws, mob taub hau, ua daus no, thiab pob txha, mob pob qij txha lossis mob leeg. Cov tsos mob no yuav pib nyob rau thawj 3 hnub tom qab koj tau txais kev txhaj tshuaj zoledronic acid thiab yuav mob ntev li 3 mus rau 14 hnub. Koj tus kws kho mob yuav hais kom koj coj cov tshuaj tiv thaiv kev mob / kub taub hau tom qab koj tau txhaj tshuaj zoledronic acid los tiv thaiv lossis kho cov tsos mob no.

Yog tias koj tau txais tshuaj zoledronic acid txhaj tshuaj tiv thaiv lossis kho cov mob pob txha, koj yuav tsum tau txais kev noj tshuaj ntxiv raws li tau teem tseg txawm hais tias koj tus kheej zoo. Koj yuav tsum nrog koj tus kws kho mob tham ib ntus txog seb koj puas tseem yuav tau txais kev kho mob ntawm cov tshuaj no.


Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia cov neeg mob rau koj (Siv Lus Qhia Txog Tshuaj Noj) thaum koj pib kho nrog zoledronic acid txhaj tshuaj thiab txhua zaus koj tau txais koob tshuaj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib Food Food and Drug Administration (FDA) lub vev xaib (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) lossis cov khw tsim lub vev xaib) kom tau txais Kev Qhia Tshuaj.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej tau txhaj tshuaj zoledronic acid,

  • qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau zoledronic acid lossis lwm yam tshuaj noj, lossis ib qho twg hauv cov tshuaj zoledronic acid txhaj. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
  • koj yuav tsum paub tias zoledronic acid txhaj yog muaj nyob rau hauv cov npe lag luam Zometa thiab Reclast. Koj tsuas yog yuav tsum kho nrog ib qho ntawm cov khoom lag luam ib zaug.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: aminoglycoside cov tshuaj tua kab mob xws li amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Neo-Rx, Neo-Fradin), paromomycin (Humatin), streptomycin, thiab tobramycin (Tobi , Nebcin); cov tshuaj aspirin thiab lwm cov tshuaj tiv thaiv tsis haum (NSAIDs) xws li ibuprofen (Advil, Motrin) thiab naproxen (Aleve, Naprosyn); kev siv tshuaj kho mob cancer; digoxin (Lanoxin, hauv Digitek); diuretics ('cov dej tshuaj') xws li bumetanide (Bumex), ethacrynic acid (Edecrin), thiab furosemide (Lasix); thiab cov tshuaj steroid qhov ncauj xws li dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), thiab prednisone (Deltasone). Ntau lwm cov tshuaj tuaj yeem cuam tshuam nrog zoledronic acid, yog li qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • qhia rau koj tus kws kho mob yog tias koj tau lossis muaj mob raum tsis ua haujlwm lossis yog koj lub qhov ncauj qhuav, tso zis tsaus ntuj, tawm hws, daim tawv qhuav, thiab lwm yam cim ntawm lub cev qhuav dej lossis nyuam qhuav muaj zawv plab, ntuav, kub cev, kis, hws ntau dhau, lossis tsis tau haus dej txaus txaus. Koj tus kws kho mob yuav tos kom txog thaum koj tsis muaj dej ntau ua ntej muab tshuaj zoledronic acid rau koj lossis yog tias koj muaj qee yam mob raum tsis tuaj yeem sau ntawv kho no rau koj. Kuj qhia rau koj tus kws kho mob yog tias koj tau txais cov calcium qis hauv koj cov ntshav. Koj tus kws kho mob tej zaum yuav soj ntsuam cov qib calcium hauv koj cov ntshav ua ntej koj pib kev kho mob thiab tsis tuaj yeem sau ntawv rau noj tshuaj no yog tias qib qis heev.
  • qhia rau koj tus kws kho mob yog tias koj tau raug kho nrog zoledronic acid lossis lwm yam bisphosphonates (Actonel, Actonel + Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax + D, Reclast, Skelid, thiab Zometa) yav dhau los; yog tias koj tau raug phais koj lub caj pas parathyroid (caj pas me me hauv caj dab) lossis lub qog caj pas lossis phais kom tshem cov ntu ntawm koj txoj hnyuv me; thiab yog tias koj tau lossis muaj lub siab ua haujlwm dua (qhov uas lub plawv tsis tuaj yeem nqus ntshav txaus rau lwm qhov ntawm lub cev) anemia (kev mob ntshav liab tsis tuaj yeem xa cov pa oxygen txaus mus rau lwm qhov ntawm lub cev); tej yam mob uas ua rau koj cov ntshav txhaws tsis los ntshav; cov ntshav calcium qis, calcium, lossis potassium nyob hauv koj cov ntshav; ib qho mob uas tiv thaiv koj lub cev los ntawm kev nqus cov khoom noj los ntawm cov khoom noj; lossis teeb meem nrog koj lub qhov ncauj, cov hniav, lossis cov pos hniav; kis mob, tshwj xeeb hauv koj lub qhov ncauj; hawb pob lossis hawb pob, tshwj xeeb yog tias nws mob ntxiv los ntawm kev noj cov tshuaj aspirin; los yog parathyroid lossis kab mob siab.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Koj yuav tsum siv cov qauv tswj kev tswj kom tsis pub muaj menyuam kom tiv thaiv kev xeeb tub thaum koj tau txais zoledronic acid. Yog tias koj xeeb tub thaum tau txais zoledronic acid, hu rau koj tus kws kho mob. Zoledronic acid tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab. Tham nrog koj tus kws kho mob yog tias koj npaj yuav muaj menyuam hauv txhua lub sijhawm tom ntej vim tias zoledronic acid yuav nyob hauv koj lub cev rau xyoo tom qab koj tsum tsis haus.
  • koj yuav tsum paub tias kev txhaj tshuaj zoledronic acid tuaj yeem ua rau mob pob txha, mob nqaij, lossis mob txha. Koj tuaj yeem pib hnov ​​cov kev mob no nyob rau ob peb hnub tom qab koj tau txais kev txhaj tshuaj zoledronic acid. Txawm hais tias hom mob no yuav pib tom qab koj tau txhaj tshuaj zoledronic acid rau qee lub sijhawm, nws yog qhov tseem ceeb rau koj thiab koj tus kws kho mob kom paub tias nws yuav tshwm sim los ntawm zoledronic acid. Hu rau koj tus kws kho mob tam sim ntawd yog tias koj hnov ​​mob hnyav thaum twg los tau thaum kho nrog zoledronic acid txhaj. Koj tus kws kho mob yuav tsum tsis txhaj tshuaj zoledronic acid rau koj thiab koj tus mob yuav ploj mus tom qab koj tsum tsis siv tshuaj kho ntxiv.
  • koj yuav tsum paub tias zoledronic acid yuav ua rau txha osteonecrosis ntawm lub puab tsaig (ONJ, qhov mob hnyav ntawm lub puab tsaig pob txha), tshwj xeeb yog tias koj tau kho hniav lossis kho hniav thaum koj siv cov tshuaj. Tus kws kho hniav yuav tsum kuaj xyuas koj cov hniav thiab ua txhua yam kev kho mob xav tau, suav nrog kev tu kom huv, ua ntej koj pib siv zoledronic acid. Nco ntsoov txhuam koj cov hniav thiab ntxuav koj lub qhov ncauj kom zoo thaum koj siv zoledronic acid. Tham nrog koj tus kws kho mob ua ntej muaj kev kho hniav thaum koj tseem siv cov tshuaj no.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Yog tias koj plam tsis tau teem caij kom tau txais zoledronic acid infusion, hu rau koj tus kws kho mob sai li sai tau.

Zoledronic acid yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias muaj ib qho ntawm cov tsos mob no, lossis cov uas tau teev tseg hauv ntu YUAV UA LI CAS LOS YOG KEV KHO MOB, muaj mob hnyav lossis tsis ploj mus:

  • khaus, liab, mob, lossis o rau hauv qhov chaw koj tau txhaj tshuaj
  • liab, o, khaus, los yog teary qhov muag lossis o ncig lub qhov muag
  • cem quav
  • xeev siab
  • ntuav
  • zawv plab
  • mob plab
  • tsis qab los noj mov
  • poob phaus
  • Kev mob siab
  • qhov ncauj tawm
  • txhawj xeeb ntau dhau
  • ntxhov siab
  • kev nyuaj siab
  • teeb meem tsis tsaug zog los yog pw tsaug zog
  • kub taub hau, ua daus no, hnoos, thiab lwm yam cim ntawm tus kab mob
  • dawb plia nyob rau hauv lub qhov ncauj
  • o, liab, khaus, kub, lossis khaus ntawm qhov chaw mos
  • paug paum dawb
  • loog lossis tingling ncig lub qhov ncauj lossis hauv cov ntiv tes lossis ntiv taw
  • plaub hau poob

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob nram qab no, hu rau koj tus kws kho mob tam sim ntawd:

  • ua pob
  • khaus
  • khaus
  • o ntawm lub qhov muag, ntsej muag, daim di ncauj, tus nplaig, caj pas, tes, caj npab, taw, pob taws, lossis ceg qis
  • txhaws qa
  • ua pa nyuaj lossis nqos
  • lub hauv siab mob
  • lub plawv khiav ceev
  • mob leeg, pob tw, lossis mob plab
  • doog ntshav los ntshav tsis txawv
  • cov pos hniav mob lossis o o
  • ua haujlwm ntawm cov hniav
  • loog lossis hnov ​​hnyav hauv lub puab tsaig
  • mob hauv qhov ncauj lossis lub puab tsaig uas tsis zoo

Zoledronic acid yuav ua rau muaj kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Raug kho nrog bisphosphonate noj tshuaj xws li zoledronic acid txhaj rau txha txha pob txha tuaj yeem ua rau muaj kev pheej hmoo ntau ntxiv uas koj yuav ua rau koj cov pob txha ncej puab. Koj yuav hnov ​​zoo li npub, mob hauv koj lub duav, puab tais, lossis ncej puab li ob peb lub lis piam los yog lub hli ua ntej cov pob txha, thiab koj yuav pom tias ib lossis ob qho ntawm koj cov ceg pob txha tau tawg txawm tias koj tsis tau poob lossis tsis tau paub lwm yam kev poob plig. Nws yog qhov txawv rau cov pob txha hauv pob txha txhawm rau txhawm rau cov neeg muaj kev noj qab haus huv, tab sis cov neeg uas muaj pob txha caj ces tuaj yeem ua txhaum cov pob txha no txawm tias lawv tsis tau txhaj tshuaj zoledronic acid txhaj. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev txhaj tshuaj zoledronic acid.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Koj tus kws kho mob yuav muab cov tshuaj no tso rau hauv nws lub chaw ua haujlwm thiab muab rau koj raws li qhov xav tau.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

  • ua npaws
  • tsis muaj zog
  • tam sim ntawd cov nqaij ntshiv lossis mob leeg ceev
  • ceev, pounding, los yog plawv dhia tsis zoo
  • kiv taub hau
  • kev tswj qhov muag tsis pom kev
  • ob lub zeem muag
  • kev nyuaj siab
  • taug kev nyuaj
  • kev tswj tsis tau ib qho ntawm koj lub cev
  • qaug dab peg
  • tsis meej pem
  • txog siav
  • mob, kub, loog lossis tingling hauv tes lossis taw
  • hais nyuaj
  • teeb meem nqos
  • tsis tso zis tsawg

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau zoledronic acid.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Ntxhoo®
  • Zometa®
Kawg Kho - 11/15/2011

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