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Subcutaneous delivery of sumatriptan in the treatment of migraine - Video abstract: 19171
Daim Duab: Subcutaneous delivery of sumatriptan in the treatment of migraine - Video abstract: 19171

Zoo Siab

Sumatriptan yog siv los kho cov tsos mob ntawm kev mob taub hau (mob heev, mob taub hau uas qee zaum nrog xeev siab los yog tsis hnov ​​lub suab thiab lub teeb). Sumatriptan yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua xaiv serotonin receptor agonists. Nws ua haujlwm los ntawm kev ua kom cov ntshav nyob hauv lub taub hau, txwv cov phiajcim kev mob kom tsis txhob raug xa mus rau lub hlwb, thiab thaiv kev tso tawm qee yam khoom ntuj uas ua rau mob, xeev siab, thiab lwm cov tsos mob ntawm migraine. Sumatriptan tsis tiv thaiv kev mob taub hau lossis txo qee tus neeg mob taub hau uas koj muaj.

Sumatriptan los ua ib ntsiav tshuaj los noj ntawm qhov ncauj. Feem ntau yog noj thawj cim ntawm mob taub hau mob taub hau.Yog hais tias koj cov tsos mob zoo dua tom qab koj noj sumatriptan tab sis rov qab los tom qab 2 teev lossis ntev dua, koj tuaj yeem noj ib ntsiav tshuaj thib ob. Txawm li cas los xij, yog tias koj cov tsos mob tsis zoo tom qab koj noj sumitriptan, tsis txhob noj ib lub tshuaj thib ob yam tsis tau hu rau koj tus kws kho mob. Koj tus kws kho mob yuav qhia koj txog qhov ntau npaum li cas ntawm cov ntsiav tshuaj uas koj tuaj yeem noj hauv 24 teev. Ua raws cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia rau qee qhov koj tsis nkag siab. Noj sumatriptan raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.


Koj tuaj yeem nqa koj thawj koob tshuaj sumatriptan hauv kws kho mob qhov chaw ua haujlwm lossis lwm qhov chaw kho mob uas koj tuaj yeem soj ntsuam kom muaj kev tsis haum tshuaj loj.

Hu rau koj tus kws kho mob yog tias mob taub hau tsis zoo dua lossis tshwm sim ntau tom qab noj sumatriptan.

Yog tias koj noj cov sumatriptan ntau zaus lossis ntev dua li lub sijhawm pom zoo, koj cov mob taub hau yuav mob heev dua lossis yuav tshwm sim ntau dua. Koj yuav tsum tsis txhob noj sumatriptan lossis lwm yam tshuaj mob taub hau ntau tshaj 10 hnub hauv ib hlis. Hu rau koj tus kws kho mob yog tias koj yuav tsum noj sumatriptan los kho ntau dua plaub mob taub hau hauv 1 lub hlis.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no qee zaum sau tseg rau lwm qhov kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj cov sumatriptan,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj ua xua ntawm sumatriptan, lwm yam tshuaj noj, lossis ib qho tshuaj twg hauv cov ntsiav tshuaj sumatriptan. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
  • tsis txhob noj sumatriptan yog tias koj tau noj ib qho ntawm cov tshuaj hauv 24 teev dhau los: lwm txoj kev xaiv serotonin receptor agonists xws li almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt) , lossis zolmitriptan (Zomig); los yog hom tshuaj siv ergot xws li bromocriptine (Parlodel), cabergoline, dihydroergotamine (DHE 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Cafergot, Ergomar, Wigraine), methylergonovine (Metherysergonovine) ), thiab pergolide (Permax).
  • tsis txhob noj sumatriptan yog tias koj noj tshuaj monoamine oxidase A (MAO-A) inhibitor xws li isocarboxazid (Marplan), phenelzine (Nardil), lossis tranylcypromine (Parnate) lossis yog tias koj tau noj ib qho ntawm cov tshuaj no 2 lub lis piam dhau los.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais qee yam ntawm cov hauv qab no: acetaminophen (Tylenol); Cov tshuaj tiv thaiv kab mob xws li amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivact), thiab Surmontil); cov tshuaj aspirin thiab lwm cov tshuaj tiv thaiv tsis haum (NSAIDs) xws li ibuprofen (Advil, Motrin) thiab naproxen (Aleve, Naprosyn); xaiv serotonin reuptake inhibitors (SSRIs) xws li citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, hauv Symbyax), fluvoxamine, paroxetine (Paxil), thiab sertraline (Zoloft); thiab xaiv serotonin / norepinephrine reuptake inhibitors (SNRIs) xws li desvenlafaxine (Pristiq), duloxetine (Cymbalta), sibutramine (Meridia), thiab venlafaxine (Effexor). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo dua rau cov kev phiv.
  • qhia rau koj tus kws kho mob yog tias koj tau lossis muaj dua li mob plawv; lub plawv nres; angina (mob hauv siab); lub plawv dhia tsis xwm yeem; stroke lossis 'mini-stroke'; lossis cov teeb meem ncig xws li varicose leeg, ntshav txhaws nyob rau hauv ob txhais ceg, Raynaud tus kab mob (teeb meem nrog ntshav ntws mus rau cov ntiv tes, ntiv taw, pob ntseg, thiab qhov ntswg), lossis ischemic plob tsis so tswj (mob ntshav raws plab thiab mob plab vim los ntshav tsawg mus rau lub txoj hnyuv). Koj tus kws kho mob yuav hais kom koj tsis txhob noj sumatriptan.
  • qhia rau koj tus kws kho mob yog tias koj haus luam yeeb lossis rog dhau; yog tias koj tau lossis tau muaj dua li ntshav siab, ntshav siab, ntshav qab zib, qaug dab peg, lossis mob siab lossis mob raum; yog tias koj tau dhau los lawm (kev hloov lub neej); lossis yog ib tus neeg hauv koj tsev neeg muaj lossis muaj mob plawv lossis mob stroke tas li.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj npaj yuav sib deev thaum koj tseem siv cov tshuaj no, nrog koj tus kws kho mob tham txog cov kev tswj kom tsis txhob muaj menyuam. Yog tias koj xeeb tub thaum noj cov tshuaj sumatriptan, hu rau koj tus kws kho mob.
  • koj yuav tsum paub tias cov tshuaj no yuav ua rau koj tsaug zog lossis kiv taub hau. Tsis txhob tsav tsheb los sis siv lub tshuab ua haujlwm kom txog thaum koj paub tias cov tshuaj no cuam tshuam rau koj li cas.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.


Sumatriptan yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • yaug
  • tingling lub siab
  • puas hnov ​​sov lossis txias
  • tsaug zog
  • nkees nkees
  • tsis muaj zog
  • kiv taub hau
  • mob plab
  • zawv plab
  • xeev siab
  • mob leeg

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob hauv qab no, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

  • mob, nruj, siab, lossis hnyav rau hauv lub hauv siab, caj pas, caj dab, thiab / lossis puab tsaig
  • maj lossis hais lus nyuaj
  • tsaus muag
  • tawg tawm nyob rau hauv ib tug txias hws
  • txog siav
  • tsis muaj zog lossis loog ntawm ib sab caj npab lossis txhais ceg
  • mob ceev heev lossis mob plab heev
  • ceev, pounding, los yog lub plawv dhia tsis xwm yeem
  • ntshav zawv plab
  • ntuav
  • mob ceev heev lossis mob plab heev
  • ceeb thawj phaus
  • paleness lossis xiav xim ntawm cov ntiv tes thiab ntiv taw
  • ua pa nyuaj lossis nqos
  • liab, o, lossis khaus ntawm lub qhov muag, ntsej muag, daim di ncauj, lossis caj pas
  • ua pob
  • khaus
  • hloov nyob rau hauv lub zeem muag
  • qaug dab peg

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).


Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws hauv chav tsev kub, nyob deb ntawm kev kub thiab noo noo (tsis nyob hauv chav dej).

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help.Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij ntsib nrog koj tus kws kho mob. Koj cov ntshav siab yuav tsum kuaj xyuas tsis tu ncua.

Koj yuav tsum khaws phau ntawv mob taub hau los ntawm kev sau cia thaum koj mob taub hau thiab thaum koj noj sumatriptan.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Imitrex® Ntsiav tshuaj
  • Treximet® (muaj Naproxen, Sumatriptan)
Kawg Kho - 11/15/2015

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