Kev kho rau hom mob qog noj ntshav

Hom phiaj kho siv cov tshuaj kom tsis txhob mob qog noj ntshav thiab sib kis tsis tau. Nws ua qhov no nrog tsawg kev puas tsuaj rau cov qog hlwb dua li lwm cov kev kho mob.

Tus txheej txheem tshuaj kho mob ua haujlwm los ntawm kev tua cov mob qog nqaij hlav ntshav thiab qee cov kab mob qog ntshav, kev kho mob xoom hauv cov hom phiaj tshwj xeeb (molecules) hauv lossis ntawm cov qog hlwb. Cov hom phiaj no tau ua ib txoj haujlwm ntawm cov qog nqaij hlav cancer loj hlob thiab ciaj sia li cas. Siv cov hom phiaj no, cov tshuaj cuam tshuam rau cov qog nqaij hlav cancer thiaj li tsis tuaj yeem kis mus tau.

Hom phiaj kho cov tshuaj ua haujlwm nyob rau ob peb yam sib txawv. Lawv yuav:

• Nthuav cov txheej txheem hauv cov qog nqaij hlav cancer uas ua rau lawv loj hlob thiab kis tau
• Cov ua rau cancer mob rau koj tus kheej tuag
• Tua cov kabmob kheesxaws ncaj qha

Cov neeg uas muaj hom mob qog nqaij hlav sib txawv tuaj yeem muaj cov hom phiaj sib txawv ntawm lawv cov qog hlwb Yog li, yog tias koj mob cancer tsis muaj hom phiaj tshwj xeeb, cov tshuaj yuav tsis ua haujlwm txwv. Tsis yog txhua txoj kev kho mob ua haujlwm rau txhua tus neeg mob qog ntshav. Tib lub sijhawm, cov qog nqaij hlav sib txawv tuaj yeem muaj tib lub hom phiaj.

Saib seb lub hom phiaj kho puas zoo rau koj, koj tus kws kho mob yuav:

• Siv ib qho hnoos qeev me me seb koj puas mob cancer
• Kuaj qhov hnoos qeev rau cov phiaj xwm tshwj xeeb (molecules)
• Yog tias lub hom phiaj raug nyob hauv koj tus mob qog nqaij hlav, koj yuav tau txais

Qee hom phiaj siv los muab tshuaj. Lwm cov raug txhaj rau txoj leeg ntshav (txoj leeg ntshav, lossis IV).

Muaj cov hom phiaj kho tuaj yeem kho qee yam mob qog noj ntshav:

• Mob nqaij hlav thiab mob ntsws
• Tus mob cancer mis
• Mob hnyuv
• Daim tawv nqaij mob cancer
• Mob ntsws cancer
• Cem plab

Lwm yam mob qog noj ntshav uas tuaj yeem kho nrog kev kho mob tshwj xeeb muaj xws li mob hlwb, pob txha, raum, mob qog, mob plab, thiab lwm yam.

Koj tus kws khomob yuav los txiavtxim saib cov kev khomob tshwj xeeb puas yog ib txoj kev xaiv rau koj mob qog nqaij hlav. Feem ntau, koj yuav tau txais hom phiaj kho nrog kev phais mob, kev kho tshuaj, kev kho tshuaj hormones, lossis kev kho hluav taws xob. Koj tuaj yeem tau txais cov tshuaj no los ntawm kev kho koj ib txwm, lossis ib feem ntawm kev sim tshuaj.

Cov kws kho mob tau xav tias cov hom phiaj kho mob tej zaum yuav muaj cov kev mob tshwm sim tsawg dua lwm cov kev kho mob cancer. Tab sis qhov ntawd tau tawm mus rau qhov tsis tseeb. Muaj kev phiv ntau los ntawm cov kev kho mob suav nrog:

• Zawv plab
• Teeb meem mob siab
• Cov teeb meem ntawm daim tawv nqaij xws li xoo pob, tawv nqaij qhuav, thiab ntsia thawv hloov
• Teeb meem ntshav txhaws thiab kho cov txhab txhab
• Ntshav siab

Ib yam li txhua yam kev khomob, koj tuaj yeem lossis tsis muaj kev mob tshwm sim. Tej zaum lawv yuav mob me lossis hnyav. Qhov zoo, lawv feem ntau ploj mus tom qab kev kho mob tas. Nws yog ib lub tswv yim zoo los nrog koj tus kws kho mob tham txog qhov yuav muaj dab tsi. Koj tus kws khomob yuav tuaj yeem pab tiv thaiv lossis txo qee qhov kev mob tshwm sim.

Cov hom phiaj kho yog qhov kev cog lus tshiab, tab sis lawv muaj qhov txwv.

• Cov kab mob cancer tuaj yeem tiv taus cov tshuaj no.
• Lub hom phiaj qee zaum hloov, yog li kev kho mob tsis ua haujlwm.
• Tus mob cancer yuav pom txawv txoj kev loj hlob thiab ciaj sia uas tsis yog nyob ntawm lub hom phiaj.
• Tshuaj yuav nyuaj los tsim rau qee lub hom phiaj.
• Cov hom phiaj kho tshiab dua tshiab thiab raug nqi ntau dua los ua. Yog li, lawv kim tshaj li lwm yam kev kho mob cancer.

Molecularly tsom anticancer tus neeg sawv cev; MTAs; Kws khomob-tsom kwm; Vascular endothelial kev loj hlob tau-tsom; VEGF-tsom; VEGFR-tsom; Tyrosine kinase inhibitor-hom phiaj; TKI-tsom; Cov tshuaj kho mob rau yus tus kheej - mob cancer

Ua KT, Kummar S. Kev kho mob rau hom mob qog noj ntshav: ຍຸກ ntawm cov neeg sawv cev molecularly. Hauv: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical OncologyCov. 6 tus ed. Philadelphia, PA: Elsevier; 2020: chap 26.

Lub koom haum Cancer National website. Cov hom phiaj mob cancer. www.cancer.gov/about-cancer/treatment/types/targeted-therapies/targeted-therapies-fact-sheet. Hloov kho thaum Lub Peb Hlis 17. 2020. Nkag mus rau Lub Peb Hlis 20, 2020.

• Mob Cancer