IgA nephropathy

IgA nephropathy yog lub raum tsis zoo uas cov tshuaj tiv thaiv hu ua IgA txhim kho hauv cov raum. Kev mob ntsws yog kev puas tsuaj, mob lossis lwm yam teeb meem nrog lub raum.

IgA nephropathy tseem hu ua tus kabmob Berger.

IgA yog protein, hu ua tshuaj tiv thaiv, uas pab lub cev tua cov kab mob sib kis. IgA nephropathy tshwm sim thaum ntau dhau ntawm cov protein no tso rau hauv lub raum. IgA txhim tsa hauv sab hauv cov hlab ntshav me me rau lub raum. Tus qauv hauv lub raum hu ua glomeruli ua rau mob thiab puas ntsoog.

Cov kev cuam tshuam tuaj yeem tshwm sim sai (mob), lossis zuj zus qeeb dhau ntau xyoo (mob glomerulonephritis ntev).

Yam txaus ntshai muaj xws li:

• Tus kheej lossis tsev neeg keeb kwm ntawm IgA nephropathy lossis Henoch-Schönlein purpura, ib daim ntawv ntawm vasculitis uas cuam tshuam rau ntau qhov ntawm lub cev
• Neeg tawv tawv dawb los yog Neeg Esxias

IgA nephropathy tuaj yeem tshwm sim hauv cov neeg ntawm txhua lub hnub nyoog, tab sis nws feem ntau cuam tshuam rau cov txiv neej hauv lawv cov hluas txog 30s.

Tej zaum yuav tsis muaj cov tsos mob rau ntau xyoo.

Thaum muaj cov tsos mob, lawv yuav suav nrog:

• Ntshav tso uas pib thaum lossis sai sai tom qab ua pa tas
• Rov ua dua ib ntu ntawm kev tso zis tsaus nti los ntshav
• O o ntawm tes thiab taw
• Cov tsos mob ntawm tus mob raum

IgA nephropathy feem ntau pom thaum tus neeg tsis muaj lwm yam tsos mob ntawm lub raum muaj ib lossis ntau ntu kev tsaus nti lossis ntshav zis.

Tsis muaj cov kev pauv hloov tshwj xeeb pom thaum kuaj lub cev. Qee zaum, ntshav siab tuaj yeem siab dhau lossis nws muaj peev xwm hloov lub cev.

Kev Xeem muaj xws li:

• Ntshav urea nitrogen (BUN) ntsuas ntsuas raum kev ua haujlwm
• Kev kuaj ntshav Creatinine los ntsuas lub raum kev ua haujlwm
• Yuav kuaj lub raum kom paub meej tias yog mob
• Mob Lub Hlaus
• Zis immunoelectrophoresis

Lub hom phiaj ntawm txoj kev kho yog pab daws cov tsos mob thiab tiv thaiv los sis ncua lub raum tsis ua hauj lwm.

Cov kev kho mob yuav suav nrog:

• Angiotensin-converting enzyme (ACE) inhibitors thiab angiotensin receptor blockers (ARBs) los tswj ntshav siab thiab o (edema)
• Corticosteroids, lwm yam tshuaj uas ua rau lub cev tsis muaj zog
• Cov roj ntses
• Cov tshuaj noj kom txo qis roj

Ntsev thiab muaj kua yuav tsum txwv kom tsis txhob o. Muaj qee lub cev yuav tsum tau noj cov protein kom tsawg mus txog rau qib qees.

Thaum kawg, ntau tus neeg yuav tsum tau kho kab mob raum thiab yuav xav lim ntshav.

IgA nephropathy mob hnyav zuj zus. Hauv ntau qhov xwm txheej, nws tsis mob loj dua txhua qhov. Koj tus mob yuav haj yam tsis zoo yog tias koj muaj:

• Ntshav siab
• Qhov ntau ntawm cov protein nyob hauv cov zis
• Nce BUN lossis qib kev tsim creatinine

Hu koj tus kws kho mob yog tias koj tso zis muaj ntshav lossis koj ua tau zis tsawg dua li ib txwm.

Kev mob siab ntsws - IgA; Berger kab mob

• Raum anatomy

Feehally J, Floege J. Immunoglobulin A nephropathy thiab IgA vasculitis (Henoch-Schönlein purpura). Hauv: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Cov Chaw Kho Mob Tshaj LojCov. 6 tus ed. Philadelphia, PA: Elsevier; 2019: chap 23.

Saha MK, Pendergraft WF, Jennette JC, Falk RJ. Thawj tus kab mob glomerular. Hauv: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner thiab Rector's RaumCov. 11th ed. Philadelphia, PA: Elsevier; 2020: chap 31.