IgA vasculitis - Henoch-Schönlein purpura

IgA vasculitis yog ib yam kab mob uas cuam tshuam rau pob txuv liab rau ntawm daim tawv nqaij, mob pob txha, mob plab, thiab glomerulonephritis (hom mob raum tsis zoo). Kuj tseem muaj npe hu ua Henoch-Schönlein purpura (HSP).

IgA vasculitis tshwm sim los ntawm kev teb tsis meej ntawm lub cev tsis muaj zog. Qhov tshwm sim yog o hauv cov kab mob me me ntshav hauv daim tawv nqaij. Cov hlab ntsha hauv cov pob qij txha, ob lub raum, lossis txoj hnyuv kuj tuaj yeem cuam tshuam. Nws tsis paub meej vim li cas qhov no tshwm sim.

Cov tsos mob feem ntau pom nyob rau cov menyuam yaus hnub nyoog 3 txog 15 xyoos, tab sis nws yuav pom hauv cov neeg laus. Nws yog feem ntau tshwm sim hauv tub hluas dua ntxhais. Coob tus neeg uas muaj tus mob no tau muaj tus kab mob ua pa rau lub lis piam ua ntej.

Cov tsos mob thiab cov yam ntxwv ntawm IgA vasculitis yuav muaj xws li:

• Purple me ntsis ntawm daim tawv nqaij (purpura). Qhov no tshwm sim hauv ze li ntawm tag nrho cov menyuam yaus nrog tus mob. Feem ntau qhov no ib txwm tshwm sim los ntawm pob tw, ob txhais ceg qis, thiab luj tshib.
• Mob plab.
• Mob tej pob txha.
• Tso zis tsis zoo (tej zaum tsis muaj tsos mob dab tsi).
• Zawv plab, qee zaum los ntshav.
• Khaus lossis angioedema.
• Xeev siab thiab ntuav.
• O o thiab mob hauv qhov nqhuab ntawm cov tub.
• Mob taub hau.

Tus kws kho mob yuav saib koj lub cev thiab saib koj cov tawv nqaij. Kev kuaj mob lub cev yuav ua rau pom tawv nqaij (nqaij tawv, txhab) thiab kev sib koom tes.

Kev ntsuam xyuas yuav muaj xws li:

• Txoj kev mob txeeb zig yuav tsum ua rau txhua kis.
• Ua kom tiav cov ntshav suav. Lub platelet yuav tsum yog qhov qub.
• Kev ntsuam xyuas coagulation: cov no yuav tsum zoo.
• Nqaij tawv nqaij, tshwj xeeb tshaj yog rau cov neeg laus.
• Kev ntsuam xyuas ntshav mus saib lwm yam ua rau cov hlab ntshav o, xws li cov kab mob lupus erythematosus, ANCA-cuam tshuam vasculitis lossis mob siab.
• Cov laus, yuav tsum kuaj raum cov raum.
• Kev ntsuam xyuas lub plab yog tias mob qhov mob.

Tsis muaj kev kho tshwj xeeb. Feem ntau yuav ploj mus lawv tus kheej. Cov leeg mob yuav ua rau mob NSAIDs xws li naproxen. Yog tias cov tsos mob tsis ploj mus, koj tuaj yeem kho tus mob corticosteroid xws li prednisone.

Tus kab mob feem ntau tau zoo dua ntawm nws tus kheej. Ob feem peb ntawm cov menyuam yaus uas muaj IgA vasculitis tsuas muaj ib ntu. Ib feem peb ntawm cov menyuam muaj ntau ntu. Tib neeg yuav tsum tau rov qab mus ntsib kws kho mob tau ntev 6 lub hlis tom qab uas mob mus nrhiav cov tsos mob ntawm lub raum. Cov neeg laus muaj feem ntau yuav muaj mob raum tsis zoo.

Teeb meem yuav suav nrog:

• Los ntshav hauv lub cev
• Kev thaiv ntawm txoj hnyuv (hauv menyuam yaus)
  
• Teeb meem lub raum (hauv qee kis tsawg)

Hu rau koj tus kws khomob yog:

• Koj tsim muaj cov tsos mob ntawm IgA vasculitis, thiab lawv nyob ntev dua ob peb hnub.
• Koj tso zis muaj ntshav lossis tso zis muaj zis tom qab kis tag.

Immunoglobulin A vasculitis; Leukocytoclastic vasculitis; Henoch-Schönlein purpura; HSP

• Henoch-Schonlein purpura ntawm sab ceg qis
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura ntawm tus menyuam mos liab ko taw
• Henoch-Schonlein purpura ntawm tus menyuam mos ob txhais ceg
• Henoch-Schonlein purpura ntawm tus menyuam mos ob txhais ceg
• Henoch-Schonlein purpura ntawm ob txhais ceg

Arntfield RT, Hicks CM. Cov kab ke lupus erythematosus thiab vasculitides. Hauv: Phab Ntsa RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Cov Tshuaj Siv Thaum Muaj Xwm Ceev: Cov Ntsiab Lus thiab Kev Siv TshuajCov. 9le ed. Philadelphia, PA: Elsevier; 2018: chap 108.

Dinulos JGH. Cov tshuaj tiv thaiv tsis haum ntshav thiab mob rau daim tawv nqaij. Hauv: Habif TP, Dinulos JGH, Chapman MS, Zug KA, eds. Daim tawv nqaij mob: Kev kuaj mob thiab khoCov. 4 tug ed. Philadelphia, PA: Elsevier; 2018: chap 11.

Feehally J, FLoege J. Immunoglobulin A nephropathy thiab IgA vasculitis (Henoch-Schönlein purpura). Hauv: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Cov Chaw Kho Mob Tshaj LojCov. 6 tus ed. Philadelphia, PA: Elsevier; 2019: chap 23.

Hahn D, Hodson EM, Willis NS, Craig JC. Cov kev tiv thaiv kev tiv thaiv thiab kho mob raum hauv Henoch-Schönlein purpura (HSP). Cochrane Database Syst RevCov. 2015; (8): CD005128. PMID: 26258874 www.ncbi.nlm.nih.gov/pubmed/ 26258874.

Lu S, Liu D, Xiao J, li al. Sib piv ntawm cov neeg laus thiab menyuam yaus nrog Henoch-Schönlein purpura nephritis. Pediatr NephrolCov. Xyoo 2015; 30 (5): 791-796. PMID: 25481021 www.ncbi.nlm.nih.gov/pubmed/25481021.

Patterson JW. Vasculopathic cov qauv tshuaj tiv thaiv. Hauv: Patterson JW, ed. Weedon's Cov Khoom Siv Tawv TawvCov. 4 tug ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2016: chap 8.

Sunderkötter CH, Zelger B, Chen KR, li al. Nomenclature ntawm cutaneous vasculitis: Dermatologic addendum rau 2012 kho International Chapel Hill Consensus Conference Nomenclature ntawm Vasculitides. Mob Pob Txha RheumatolCov. 2018; 70 (2): 171-184. PMID: 29136340 www.ncbi.nlm.nih.gov/pubmed/29136340.