Kuv Yuav Tsum Tau Paub Dab Tsi Txog Cov Kev Phiv Los Ntawm Txoj Kev Kho CML? Cov Lus Nug rau Koj Tus Kws Kho Mob

Zoo Siab

• Kuv yuav tsum paub dab tsi txog kev phiv los ntawm kev kho mob CML?
• Kev Kho Mob Tyrosine kinase inhibitor (TKI)
• Kev siv roj ntsha
• Kws khomob
• Qia cell hloov
• Kev plees kev yi
• Puas muaj kev xaiv rau kev tswj cov kev mob tshwm sim?
• Cov kev mob tshwm sim mus ntev tom qab kho tas?
• Kuv tuaj yeem nrhiav kev txhawb nqa qhov twg?
• Cov nqa mus

Txheej txheem cej luam

Koj txoj kev taug mob mus ntev li ntawm tus mob myeloid leukemia (CML) tuaj yeem koom nrog ntau yam kev kho mob. Txhua yam ntawm cov no tuaj yeem muaj cov kev mob tshwm sim sib txawv los yog cov nyom. Tsis yog txhua tus neeg ua tib txoj kev cuam tshuam rau kev cuam tshuam, yog li qee zaum koj tus kws kho mob yuav hloov pauv rau koj hom phiaj xwm kho.

Nws tuaj yeem pab tham nrog koj tus kws kho mob ua ntej txog qhov kev pheej hmoo ntawm kev phiv. Qhov kev sib tham no tuaj yeem pab koj npaj tau, tshwj xeeb yog tias koj cov kev kho tau hloov.

Nws tseem tuaj yeem muab cov phiaj xwm kev ua haujlwm rau koj. Nyeem rau kawm kom paub ntau ntxiv txog yuav pib sib tham nrog koj tus kws kho mob li cas kom koj thiaj tawm mus zoo.

Kuv yuav tsum paub dab tsi txog kev phiv los ntawm kev kho mob CML?

Koj txoj kev npaj khomob rau CML yuav suav nrog:

• tshuaj kho mob, xws li cov siv rau cov hom phiaj kho lossis kev siv tshuaj kho mob
• lub qia cell hloov ua lwm yam
• kev siv tshuaj lom lossis kho mob
• kev phais mob

Txhua yam ntawm cov kev cuam tshuam no tuaj nrog cov kev pheej hmoo ntawm cov kev mob tshwm sim los yog cov nyom. Nco ntsoov tias, yog tias koj tus kws kho mob pom zoo rau kev kho mob, lawv tau txiav txim siab qhov muaj txiaj ntsig ntawm kev kho mob kom ntau dua li cov kev phom sij.

Koj yuav tsum qhia koj tus kws kho mob txhua lub sijhawm yog tias koj cov kev mob tshwm sim txawv txawv, tsis tuaj yeem tswj tau, lossis ua rau koj txhawj xeeb. Ntau yam kev mob tshwm sim tuaj yeem kho nrog kev siv tshuaj kho mob, lwm yam kev kho mob, lossis los ntawm qhov hloov pauv ntawm koj daim phiaj xwm kho mob.

Koj tus kws kho mob tuaj yeem qhia koj ntxiv txog thaum twg koj tuaj yeem tswj hwm cov kev mob tshwm sim hauv tsev thiab thaum twg koj yuav tsum nrhiav kev kho mob.

Kev Kho Mob Tyrosine kinase inhibitor (TKI)

TKIs yog ib hom kev kho mob rau lub hom phiaj, txhais tau tias lawv tau siv los tua cov qog nqaij hlav cancer yam tsis ua kom lub hlwb noj qab haus huv. Piv txwv, cov tshuaj uas TKIs suav nrog:

• imatinib mesylate (Gleevec) kev qhia
• dasatinib (Sprycel)
• nilotinib (Tasigna)
• bosutinib (Bosulif)
• ponatinib (Iclusig)

Rau feem ntau ntawm cov tib neeg, bosutinib thiab ponatinib tsuas yog siv tom qab lwm cov tshuaj TKI tau sim.

Cov kev mob tshwm sim los ntawm TKI tshuaj muaj xws li:

• xeev siab
• ntuav
• daim tawv nqaij qhuav lossis khaus
• nkees
• mob leeg
• mob tej pob txha

Txhua TKI tshuaj yuav muaj nws cov kev mob tshwm sim muaj. Koj kev paub yuav yog nyob ntawm seb cov tshuaj koj noj thiab seb koj teb rau nws li cas.

Muaj qee kis, Kev Kho Mob TKI tuaj yeem muaj cov kev mob tshwm sim loj heev, xws li ntshav liab, ntshav kis, lossis los ntshav. Cov no tsis tshua muaj. Lwm qhov kev mob tshwm sim tsawg dua xws li teeb meem plawv, teeb meem daim siab, mob ntsws, lossis cov kua dej ceev ceev ib puag ncig lub plawv thiab lub ntsws.

Koj pawg neeg saib xyuas kev noj qab haus huv yuav saib xyuas koj kom pom cov kev mob tshwm sim hnyav dua. Yog tias koj pom muaj qhov hloov sai sai uas koj xav tias yuav muaj qhov tshwm sim tsis zoo ntawm koj cov tshuaj, qhia rau koj tus kws kho mob paub.

Kev siv roj ntsha

Hom kev kho no tseem hu ua kev kho mob tiv thaiv. Piv txwv, qee cov neeg tau txais kev kho mob xws li interferon alfa los tswj CML. Nws yuav raug teem txhawm rau kom nce ntshav hauv cov ntshav tsawg.

Muaj kev phiv ntau ntawm cov tshuaj interferon alfa:

• tawv nqaij liab thiab khaus
• cov tsos mob khaub thuas
• xeev siab
• ntuav
• tsis qab los noj mov
• nkees
• mob qhov ncauj
• zawv plab
• plaub hau poob
• dajntoo

Nws tseem muaj peev xwm cuam tshuam rau cov tshuaj interferon alfa ua rau muaj kev fab tshuaj rau qee tus neeg, tab sis qhov no muaj tsawg.

Kws khomob

Kev siv tshuaj kho mob ua haujlwm los ntawm kev tiv thaiv qee hom qog ntshav ntawm kev loj hlob, suav nrog kev mob qog ntshav. Txoj kev kho mob tuaj yeem tua cov hlwb lossis ua kom lawv tsis txhob faib tawm.

Muaj ntau cov tshuaj siv rau kev kho tshuaj, thiab cov qee zaum qee zaum txuas nrog lwm cov kev kho mob. Kev sib xyaw ntau ntawm cov tshuaj uas cov neeg kho CML tau txais yog cytarabine thiab interferon alfa.

Cov kev mob tshwm sim los ntawm kev siv tshuaj khomob rau CML suav nrog:

• mob qhov ncauj
• mob caj pas
• nkees
• plaub hau poob
• zawv plab
• cem quav
• tsis qab los noj mov
• xeev siab
• ntuav
• teeb meem nrog kev muaj me nyuam

Koj tus kws kho mob tuaj yeem muab cov lus qhia ntxiv rau koj txog kev phiv los ntawm cov kev siv tshuaj khomob uas koj tau txais.

Qia cell hloov

Lub qog cell qog ua kom cov qe hauv lub cev noj qab nyob zoo.

Muaj ntau yam khoom sib hloov uas siv rau CML. Cov tib neeg uas tau txais ib qho allogeneic cell cell hloov ntshav tau los ntawm cov neeg pub nyiaj. Cov neeg no yog qhov pheej hmoo txaus ntshai rau qhov mob hu ua kev sib tsoo ntawm tus kab mob (GVHD).

GVHD tshwm sim thaum tus pub cov tshuaj tiv thaiv lub cev tiv thaiv lub cev noj qab nyob zoo. Vim tias txoj kev pheej hmoo no, cov neeg tau txais tshuaj kho kom muaj zog tiv thaiv kab mob hauv ib hnub lossis ob hnub ua ntej hloov ntshav. Txawm hais tias tom qab noj cov tshuaj tiv thaiv, nws tseem muaj peev xwm rau ib tus neeg ntsib GVHD, tab sis nws tsis tshua muaj.

Kev plees kev yi

Qee cov neeg nrog CML yuav tshem lawv tus po tawm. Lub hom phiaj ntawm qhov kev phais mob no yog txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau tiv thaiv ntshav los yog tiv thaiv qhov tsis xis nyob yog tias hloov khoom nruab nrog ntau vim tias CML.

Nrog rau kev phais ib qho twg, muaj lwm yam tshwm sim tau. Cov teeb meem los ntawm cov txheej txheem no tuaj yeem suav nrog:

• kis tau tus mob
• xeev siab
• ntuav
• kev mob
• txo lub cev tsis muaj zog

Koj pawg neeg saib xyuas kev noj qab haus huv yuav ua cov kauj ruam los txo koj txoj kev pheej hmoo ntawm cov teeb meem ntsig txog kev phais mob. Feem ntau ntawm cov neeg tau rov qab los ntawm kev phais mob nyob rau hauv plaub mus rau rau lub lis piam.

Puas muaj kev xaiv rau kev tswj cov kev mob tshwm sim?

Koj tus kws kho mob tuaj yeem pab koj tswj hwm kev mob tshwm sim los ntawm kev kho mob CML. Qee zaum, qhov ntawd yuav txhais tau tias hloov mus rau txoj kev kho mob tshiab.

Nws kuj tseem txhais tau tias yog siv cov tshuaj ntxiv los kho mob tshwj xeeb. Piv txwv li, koj tus kws kho mob yuav qhia cov kev yuav tshuaj lossis cov tshuaj yuav tom khw kom txo qhov xeev siab los yog kho pob tawv nqaij.

Nws kuj tseem muaj ntau yam koj tuaj yeem ua tom tsev tuaj yeem tswj tau cov kev mob tshwm sim:

• Kev ua kom lub cev muaj zog thiab lub teeb yuav pab kom qaug zog.
• Kev tiv thaiv koj cov tawv nqaij los ntawm lub hnub tuaj yeem pab kom ua pob khaus.

Thaum kho CML, koj tuaj yeem ua cov kauj ruam kom xis nyob dua. Kav tsij txuas lus nrog koj tus kws kho mob.

Cov kev mob tshwm sim mus ntev tom qab kho tas?

Raws li lub ntsej muag Leukemia thiab Lymphoma Society, qee cov neeg yuav muaj kev mob tshwm sim tom qab lawv pib kho mob tas.

Cov neeg feem coob nyob nrog CML siv TKIs mus tas lawv lub neej. Nrog kev saib xyuas mob, qee cov neeg muaj peev xwm txo qis qis. Nws yog ib qho tseem ceeb uas yuav tsum tsis txhob hloov koj cov tshuaj noj tshwj tsis yog koj tus kws kho mob pom zoo.

Koj cov lus teb rau koj txoj kev npaj khomob yuav hloov raws sijhawm. Koj tseem yuav muaj cov kev mob tshwm sim tshiab yog tias koj hloov TKI tshuaj. Koj tus kws kho mob tuaj yeem qhia koj txog qhov koj tuaj yeem xav tau raws li cov tshuaj tshwj xeeb uas koj tau noj.

Kuv tuaj yeem nrhiav kev txhawb nqa qhov twg?

Coob tus neeg nyob nrog CML nrhiav cov ntaub ntawv muaj txiaj ntsig zoo thiab muaj kev koom tes los ntawm kev sib txuas nrog lwm tus neeg uas nyob nrog tus mob no. Nws tuaj yeem yog qhov pab tau thiab nplij siab los hais lus nrog cov neeg tau sib koom los yog qhov zoo sib xws.

Koj tus kws kho mob lossis chaw kuaj mob hauv nroog tuaj yeem pab koj nrhiav cov pab neeg hauv ib cheeb tsam. Lub Leukemia & Lymphoma Society muaj cov ntaub ntawv hais txog pab pawg txhawb nqa los ntawm lawv cov tshooj hauv zej zog. American Cancer Society tseem muaj cov khoom siv online rau koj kom ncav cuag.

Cov nqa mus

Txhua txoj kev kho mob tuaj nrog kev mob tshwm sim, tab sis tsis txhais tau tias koj yuav ntsib lawv. Cov neeg sib txawv nyias muaj nyias cov lus teb rau kev noj tshuaj. Los ntawm kev koom tes nrog koj tus kws kho mob, koj tuaj yeem tswj cov kev mob tshwm sim uas koj muaj dhau los.