Mob Vogt-Koyanagi-Harada yog dab tsi

Zoo Siab

• Dab tsi ua
• Cov tsos mob ua tau
• Yuav kho tus mob li cas

Vogt-Koyanagi-Harada Syndrome yog ib yam mob uas tsis tshua muaj mob uas cuam tshuam cov ntaub so ntswg uas muaj melanocytes, xws li lub qhov muag, lub hauv nruab nrab hauv lub paj hlwb, pob ntseg thiab tawv nqaij, ua rau muaj qhov mob o nyob rau ntawm qhov muag ntawm lub qhov muag, feem ntau cuam tshuam nrog dermatological thiab hnov ​​teeb meem.

Tus mob no feem ntau yog rau cov neeg hluas hnub nyoog thaj tsam 20 txog 40, nrog cov poj niam yog cov cuam tshuam tshaj plaws. Txoj kev kho yog muaj kev tswj hwm ntawm corticosteroids thiab immunomodulators.

Dab tsi ua

Qhov ua kom muaj tus kab mob no tseem tsis tau paub, tab sis ntseeg tau tias nws yog tus kab mob autoimmune, nyob rau hauv uas muaj kev txhoj puab heev nyob rau saum npoo ntawm melanocytes, txhawb kev mob tiv thaiv nrog ib qho tshwm sim ntawm T lymphocytes.

Cov tsos mob ua tau

Cov tsos mob ntawm tus mob no nyob ntawm theem koj yog:

Prodromal theem

Nyob rau qib no, cov kab mob ua rau lub cev zoo ib yam li cov khaub thuas zoo li tau khaub thuas tshwm, nrog cov tsos mob ntawm lub paj hlwb tau ntev li ob peb hnub xwb. Cov tsos mob tshwm sim feem ntau yog ua npaws, mob taub hau, mob caj dab, xeev siab, kiv taub hau, hnov ​​ib ncig ntawm lub qhov muag, tinnitus, cov leeg nqaij tsis muaj zog, ib leeg tuag tes tuag taw ntawm ib sab ntawm lub cev, tsis yooj yim hais cov lus kom raug los yog pom cov lus, photophobia, kua muag, tawv nqaij thiab tawv taub hau kev tiv thaiv tsis haum.

Uveitis theem

Nyob rau theem no, kev tshwm sim ovular predominate, xws li mob ntawm cov leeg thaum retina, tsis tshua pom kev thiab thaum kawg cuam tshuam ntawm qhov retina. Qee tus neeg yuav hnov ​​pob ntseg hnov ​​pob ntseg, mob thiab tsis xis nyob hauv pob ntseg.

Mob theem

Hauv cov qib no, cov tsos mob ovular thiab dermatological yog pom, xws li vitiligo, depigmentation ntawm cov plaub muag, pob muag, uas tuaj yeem dhau los ntawm lub hlis mus rau xyoo. Vitiligo nyhav zoo li muab faib ua yam ntxwv dua lub taub hau, ntsej muag thiab pob tw, thiab tuaj yeem mus tas li.

Cov theem tsis tshua mob heev

Nyob rau theem no cov neeg tuaj yeem txhim kho kev mob ntawm retina, cataracts, glaucoma, choroidal neovascularization thiab subretinal fibrosis.

Yuav kho tus mob li cas

Kev kho yog muaj cov thawj coj ntawm kev txhaj tshuaj ntau ntau ntawm corticosteroids xws li prednisone lossis prednisolone, tshwj xeeb tshaj yog nyob rau theem mob huam sai, tsawg kawg 6 lub hlis. Qhov kev kho no tuaj yeem ua rau tsis kam thiab ua rau daim siab ua haujlwm thiab nyob rau hauv cov rooj plaub no nws muaj peev xwm xaiv rau kev siv betamethasone lossis dexamethasone.

Hauv cov neeg nyob rau hauv uas cov kev mob tshwm sim ntawm corticosteroids ua rau lawv qhov kev siv tshuaj tsawg kawg nkaus tsis muaj kev tiv thaiv, cov tshuaj tiv thaiv kab mob xws li cyclosporine A, methotrexate, azathioprine, tacrolimus lossis adalimumab tuaj yeem siv, uas tau siv nrog cov txiaj ntsig zoo.

Thaum muaj kev tawm tsam corticosteroids thiab nyob rau hauv cov neeg uas tsis teb los kho immunomodulatory, cov tshuaj tiv thaiv kab mob immunoglobulin yuav siv tau.