Pyrimethamine (Daraprim)

Zoo Siab

• Nqi
• Cov Khoom Qhia
• Yuav siv li cas
• Sab sij huam
• Cov Yuav Tsum Tau Ua

Daraprim yog tshuaj noj tshuaj tiv thaiv kab mob uas siv pyrimethamine ua cov khoom xyaw, ua rau tuaj yeem tiv thaiv kev tsim cov tshuaj enzymes los ntawm protozoan lub luag haujlwm rau malaria, yog li kho tus kab mob.

Daraprim tuaj yeem muas tau los ntawm cov chaw muag tshuaj uas muaj cov tshuaj tshwj xeeb hauv cov thawv uas muaj 100 ntsiav tshuaj ntawm 25 mg.

Nqi

Tus nqi ntawm Daraprim yog kwv yees li 7 reais, txawm li cas los xij tus nqi yuav txawv raws qhov chaw nyob qhov twg yuav yeeb tshuaj.

Cov Khoom Qhia

Daraprim yog qhia rau kev tiv thaiv thiab kho mob malaria, nrog rau lwm yam tshuaj. Ntxiv rau, Daraprim kuj tseem siv tau los kho Tus Mob Toxoplasmosis, raws li tus kws kho mob tau hais tseg.

Yuav siv li cas

Kev siv Daraprim sib txawv raws li lub hom phiaj ntawm kev kho mob thiab lub hnub nyoog ntawm tus neeg mob, nrog cov lus qhia dav dav suav nrog:

Kev tiv thaiv tus kabmob malaria

• Cov neeg loj thiab menyuam yaus ntau dua 10 xyoo: 1 ntsiav tshuaj hauv ib lub lis piam;
• Cov menyuam hnub nyoog 5 txog 10 xyoo: ½ Ntsiav tshuaj ib lim tiam;
• Cov me nyuam qis dua 5 xyoos: ¼ ntsiav tshuaj ib lim tiam.

Kho mob npaws

• Cov neeg loj thiab menyuam yaus hnub nyoog tshaj 14 xyoos: 2 rau 3 ntsiav tshuaj ua ke nrog 1000 mg rau 1500 mg ntawm sulfadiazine hauv ib zaug tshuaj;
• Cov menyuam hnub nyoog 9 txog 14 xyoos: 2 ntsiav tshuaj ua ke nrog 1000 mg ntawm sulfadiazine hauv ib zaug tshuaj;
• Cov menyuam hnub nyoog 4 txog 8 xyoo: 1 ntsiav tshuaj ua ke nrog rau 1000 mg ntawm sulfadiazine hauv ib zaug tshuaj;
• Cov menyuam tsis tau muaj 4 xyoos: ½ Ntsiav tshuaj ua ke nrog 1000 mg ntawm sulfadiazine hauv ib koob tshuaj.

Sab sij huam

Cov kev mob tshwm sim tseem ceeb ntawm Daraprim suav nrog kev ua xua ntawm daim tawv nqaij, mob pob ntseg, xeev siab, mob plab, raws plab, tsis qab los, ntshav tso zis thiab hloov ntshav kuaj.

Cov Yuav Tsum Tau Ua

Daraprim yog contraindicated nyob rau hauv cov neeg mob uas muaj megaloblastic anemia vim muaj folate deficiency lossis hypersensitivity rau pyrimethamine lossis ib qho ntawm cov qauv ntawm cov mis.