Cov Kev Ntsuas Tshuaj
Zoo Siab
- Tshuaj pharmacogenetic yog dab tsi?
- Nws siv rau dab tsi?
- Vim li cas kuv thiaj xav tau cov tshuaj pharmacogenetic?
- Muaj dab tsi tshwm sim thaum kuaj tshuaj pharmacogenetic?
- Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?
- Puas muaj kev pheej hmoo rau kev kuaj?
- Cov txiaj ntsig li cas?
- Puas muaj lwm yam ntxiv uas kuv xav paub txog kev sim tshuaj pharmacogenetic?
- Ua tim khawv
Tshuaj pharmacogenetic yog dab tsi?
Pharmacogenetics, tseem hu ua pharmacogenomics, yog kev kawm txog cov noob caj noob ces cuam tshuam rau lub cev kev teb rau qee yam tshuaj. Cov noob yog cov seem ntawm DNA tso tawm los ntawm koj niam thiab koj txiv. Lawv nqa cov ntaub ntawv uas txiav txim siab koj cov xeeb ceem tshwj xeeb, xws li qhov siab thiab xim qhov muag. Koj cov noob kuj yuav cuam tshuam li cas ib qho yeeb tshuaj tshwj xeeb rau koj.
Cov noob ntshav tuaj yeem yog vim li cas tib cov tshuaj ntawm tib cov tshuaj yuav ua rau tib neeg sib txawv. Cov noob kuj yuav yog vim li cas qee tus neeg muaj kev phiv tshuaj tsis zoo rau lub tshuaj, thaum lwm tus tsis muaj.
Pharmacogenetic testing saib rau ntawm cov noob tshwj xeeb los pab nrhiav cov tshuaj thiab kev siv ntau npaum uas yuav zoo rau koj.
Lwm lub npe: pharmacogenomics, kuaj tshuaj pharmacogenomic
Nws siv rau dab tsi?
Kev siv tshuaj rau hauv lub cev yuav tau siv rau:
- Tshawb nrhiav seb ib hom tshuaj kho mob puas ua haujlwm zoo rau koj
- Tshawb nrhiav yam tshuaj zoo tshaj plaws rau koj
- Kwv yees seb koj puas yuav muaj cov kev mob tshwm sim loj heev los ntawm cov tshuaj
Vim li cas kuv thiaj xav tau cov tshuaj pharmacogenetic?
Koj tus kws kho mob yuav xaj kom kuaj mob ua ntej koj pib siv ib hom tshuaj, lossis yog koj noj tshuaj uas tsis ua haujlwm thiab / lossis ua rau muaj kev phiv tshuaj tsis zoo.
Cov tshuaj sim ntawm lub cev tsuas yog muaj rau cov tshuaj tiv thaiv tsawg tsawg. Hauv qab no yog qee cov tshuaj thiab cov noob uas tuaj yeem kuaj. (Cov noob npe feem ntau yog muab hauv cov tsiaj ntawv thiab lej.)
Tshuaj kho mob | Cov Noob |
---|---|
Warfarin: ntshav thinner | CYP2C9 thiab VKORC1 |
Plavix, cov ntshav ntshav nyias | CYP2C19 |
Cov tshuaj tiv thaiv kev ntxhov siab, tshuaj tua kabmob | CYP2D6, CYPD6 CYP2C9, CYP1A2, SLC6A4, HTR2A / C |
Tamoxifen, kev kho mob qog noj ntshav mis | CYPD6 |
Cov tshuaj tiv thaiv | DRD3, CYP2D6, CYP2C19, CYP1A2 |
Cov kev kho mob rau kev saib xyuas qhov tsis taus | D4D4 |
Carbamazepine, kev kho mob rau mob vwm | HLA-B * 1502 |
Abacavir, ib txoj kev kho mob HIV | HLA-B * 5701 |
Kev Siv Opioids | OPRM1 |
Statins, tshuaj uas kho cov rog | SLCO1B1 |
Cov kev kho mob rau cov menyuam yaus mob qog ntshav thiab qee qhov mob autoimmune tsis zoo | TMPT |
Muaj dab tsi tshwm sim thaum kuaj tshuaj pharmacogenetic?
Kev ntsuam xyuas feem ntau yog ua rau ntshav lossis cov qaub ncaug.
Rau kev ntsuas ntshav, tus kws saib xyuas kev noj qab haus huv yuav nqa ntshav los ntawm txoj hlab ntshav hauv koj txhais caj npab, siv rab koob me me. Tom qab cov koob raug tso nkag, cov ntshav me me yuav raug sau rau hauv lub khob kuaj lossis vial. Koj tuaj yeem hnov me ntsis thaum cov koob nkag mus lossis tawm. Qhov no feem ntau yuav siv sijhawm tsawg dua tsib feeb.
Ua rau kom muaj qaub ncaug, Nug koj tus kws kho mob kom qhia rau koj txog kev muab koj cov hnoos qeev.
Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?
Feem ntau koj tsis tas yuav muaj kev npaj tshwj xeeb txog kev kuaj ntshav. Yog tias koj tau ntsuas cov qaub ncaug, koj yuav tsum tsis txhob noj, haus, lossis haus luam yeeb rau 30 feeb ua ntej ntsuas.
Puas muaj kev pheej hmoo rau kev kuaj?
Txoj kev kuaj ntshav muaj feem me me. Koj yuav muaj mob me lossis doog ntshav ntawm qhov chaw tso rab koob, tab sis feem ntau cov tsos mob ploj mus sai.
Nws tsis muaj kev pheej hmoo rau qhov kuaj cov qaub ncaug.
Cov txiaj ntsig li cas?
Yog tias koj raug sim ua ntej pib txoj kev kho mob, kev tshuaj ntsuam tuaj yeem ua pov thawj pom tias ib qho tshuaj yuav ua rau muaj txiaj ntsig thiab / lossis yog tias koj muaj kev pheej hmoo ntawm kev phiv loj heev. Qee yam kev sim, xws li cov tshuaj uas siv los kho kho tus kabmob sib chwv thiab mob HIV, tuaj yeem ua rau pom tias koj muaj feem yuav phom sij txog kev phom sij. Yog li, koj tus kws khomob yuav sim nrhiav lwm txoj kev khomob.
Cov kev sim uas tshwm sim ua ntej thiab thaum koj tab tom kho mob tuaj yeem pab koj tus kws kho mob kom paub qhov tseeb.
Yog koj muaj lus nug txog koj cov txiaj ntsig, nrog koj tus kws kho mob tham.
Kawm paub ntau ntxiv txog cov kev sim hauv chaw soj ntsuam, cov chaw siv ntsuas, thiab nkag siab cov txiaj ntsig tau.
Puas muaj lwm yam ntxiv uas kuv xav paub txog kev sim tshuaj pharmacogenetic?
Cov tshuaj sim tshuaj tsuas yog siv los nrhiav tus neeg cov lus teb rau qee yam tshuaj. Nws tsis zoo tib yam li kev kuaj ntsuas caj ces. Cov kev sim tshuaj feem ntau tau siv los pab kuaj cov kab mob lossis kev pheej hmoo ntawm tus kab mob, txheeb xyuas tsev neeg, lossis txheeb xyuas qee tus neeg hauv kev tshawb nrhiav txhaum.
Ua tim khawv
- Hefti E, Blanco J. Teev Cov Kev Tshuaj Ntsuam Kev Tshuaj nrog Kev Ua Haujlwm Tam Sim No (CPT) Cov Cai, Kev Tshuaj Xyuas Txog Yav Dhau Los thiab Tam Sim No. J AHIMA [Is Taws Nem]. 2016 Jan [hais 2018 Jun 1]; 87 (1): 56–9. Muaj los ntawm: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998735
- Kev Tshuaj Ntsuam Xyuas online [Internet]. Washington D.C: Koom Haum Asmeskas rau Chaw Kuaj Mob; c2001–2018. Cov Kev Ntsuas Tshuaj Pharmacogenetic; [kho tshiab 2018 Jun 1; raug nplua 2018 Jun 1]; [txog 2 ntxaij]. Muaj los ntawm: https://labtestsonline.org/tests/pharmacogenetic-tests
- Kev Tshuaj Ntsuam Xyuas online [Internet]. Washington D.C: Koom Haum Asmeskas rau Chaw Kuaj Mob; c2001–2018. Lub ntiaj teb ntawm kev tshuaj ntsuam genetic ntsuas; [hloov tshiab 2017 Nov 6; raug nplua 2018 Jun 1]; [txog 2 ntxaij]. Muaj los ntawm: https://labtestsonline.org/articles/genetic-testing?start=4
- Mayo Clinic: Chaw rau Chaw Kho Mob Nkeeg [Internet]. Mayo Foundation for Medical Education thiab Tshawb Fawb; c1998–2018. Tshuaj Ntsuam Cov Yeeb-Tshuaj; [hais 2018 Jun 1]; [txog 3 ntxaij]. Muaj los ntawm: http://mayoresearch.mayo.edu/center-for-fivsis-edicine/drug-gene-testing.asp
- Mayo Clinic: Chaw rau Chaw Kho Mob Nkeeg [Internet]. Mayo Foundation for Medical Education thiab Tshawb Fawb; c1998–2018. CYP2D6 / Tamoxifen Pharmacogenomic Lab Tshuaj; [hais 2018 Jun 1]; [txog 5 ntxaij].Muaj los ntawm: http://mayoresearch.mayo.edu/center-for-fivised-medicine/cyp2d6-tamoxifen.asp
- Mayo Clinic: Chaw rau Chaw Kho Mob Nkeeg [Internet]. Mayo Foundation for Medical Education thiab Tshawb Fawb; c1998–2018. HLA-B * 1502 / Carbamazepine Lab Pharmacogenomic Lab; [hais 2018 Jun 1]; [txog 4 ntxaij]. Muaj los ntawm: http://mayoresearch.mayo.edu/center-for-fivate-medicine/hlab1502-carbamazephine.asp
- Mayo Clinic: Chaw rau Chaw Kho Mob Nkeeg [Internet]. Mayo Foundation for Medical Education thiab Tshawb Fawb; c1998–2018. HLA-B * 5701 / Abacavir Pharmacogenomic Lab; [hais 2018 Jun 1]; [txog 4 ntxaij]. Muaj los ntawm: http://mayoresearch.mayo.edu/center-for-fivised-medicine/hlab5701-abacavir.asp
- Mayo Clinic: Mayo Medical Laboratories [Is Taws Nem]. Mayo Foundation for Medical Education thiab Tshawb Fawb; c1995–2018. Daim Ntawv Kuaj ID: PGXFP: Tsom Xam Pharmacogenomics Vaj Huam Sib Luag: Nthuav Qhia; [hais 2018 Jun 1]; [txog 3 ntxaij]. Muaj los ntawm: https://www.mayomedicallaboratories.com/test-catalog/Specimen/65566
- National Cancer Institute [Internet]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; NCI Lus Txhais ntawm Cancer Cov Lus Cog Tseg: noob; [hais 2018 Jun 1]; [txog 3 ntxaij]. Muaj los ntawm: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q ;=gene
- Teb Chaws Lub Plawv, Lub Ntsws, thiab Koom Haum Ntshav [Internet]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Kuaj ntshav; [hais 2018 Jun 1]; [txog 3 ntxaij]. Muaj los ntawm: https://www.nhlbi.nih.gov/health-topics/blood-tests
- NIH Lub Koom Haum Hauv Tebchaws ntawm General Medical Science [Is Taws Nem]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Pharmacogenomics; [hloov tshiab 2017 Oct; raug nplua 2018 Jun 1]; [txog 4 ntxaij]. Muaj los ntawm: https://www.nigms.nih.gov/education/Pages/factsheet-pharmacogenomics.aspx
- NIH Lub Tebchaws Asmeskas Cov Tsev Kuaj Tshuaj (Genetics) Hauv Tsev [Hauv Is Taws Nem]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Pharmacogenomics yog dab tsi ?; 2018 Tsib Hlis 29 [hais 2018 Jun 1]; [txog 4 ntxaij]. Muaj los ntawm: https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics
- Kev Noj Qab Haus Huv UF: University of Florida Health [Is Taws Nem]. Tsev kawm ntawv ntawm Florida; c2018. Koj cov noob caj dab cuam tshuam txog cov tshuaj zoo li cas rau koj; 2016 Jan 11 [hloov tshiab 2018 Jun 1; raug nplua 2018 Jun 1]; [txog 2 ntxaij]. Muaj los ntawm: https://ufhealth.org/blog/how-your-genes-influence-what-medicines-are-right-you
- UW Health American Tsev Neeg Cov Menyuam Lub Tsev Kho Mob [Is Taws Nem]. Madison (WI): University of Wisconsin Cov Tsev Kho Mob thiab Chaw Kho Mob; c2018. Cov Menyuam Txoj Kev Noj Qab Haus Huv: Pharmacogenomics; [hais 2018 Jun 1]; [txog 4 ntxaij]. Muaj los ntawm: https://www.uwhealthkids.org/kidshealth/en/parents/pharmacogenomics.html/
Cov ntaub ntawv ntawm lub xaib no yuav tsum tsis txhob siv los hloov chaw kho mob lossis tswv yim kho mob. Hu rau kws kho mob yog tias koj muaj lus nug txog koj txoj kev noj qab haus huv.