Puas yog Pancreatic Cancer Hereditary? Kawm Cov Teeb Meem Vim Ua Dab Tsi thiab Muaj Qhov Phiaj Sij Hawm
Zoo Siab
- Dab tsi ua rau muaj mob qog ntshav, thiab leej twg yuav muaj teeb meem?
- Kab mob qog ntshav yog mob ntau npaum li cas?
- Cov tsos mob los saib rau
- Thaum twg mus ntsib koj tus kws kho mob
- Dab tsi tshwm sim los ntawm kev kuaj pom
- Muaj dab tsi tshwm sim txuas ntxiv?
Txheej txheem cej luam
Txoj kev mob qog nqaij hlav pib thaum pib qog cov kab mob rau cov txiav ua ntej nrog DNA.
Cov qog hlwb tsis zoo no tsis tuag, raws li cov keeb neeg niaj hnub ua, tab sis txuas ntxiv tsim dua tshiab. Nws yog txoj kev tsim cov qog hlwb no uas tsim cov qog.
Hom mob qog nqaij hlav feem ntau pib hauv cov kab mob ua kom txoj hlab ntuag ntshav nrog nrog txiav. Nws kuj tuaj yeem pib hauv lub hlwb neuroendocrine lossis lwm cov hlwb tsim cov keeb.
Kev mob qog nqaij hlav hauv qee tsev neeg. Feem pua me me ntawm kev hloov caj ces tau koom nrog kabmob kheesxaws pancreatic. Feem ntau nrhiav tau.
Muaj qee yam ntawm lwm yam uas tuaj yeem ua rau koj muaj feem yuav mob qog nqaij hlav cancer pancreatic. Qee yam ntawm no tuaj yeem hloov pauv, tab sis lwm qhov tsis tuaj yeem hloov. Khaws nyeem kom kawm paub ntau ntxiv.
Dab tsi ua rau muaj mob qog ntshav, thiab leej twg yuav muaj teeb meem?
Twb qhia paub hais tias yog vim li cas ntawm kev mob cancer rau txiav pancreatic. Qee yam noob keeb hloov, ob qho tib si pub thiab tau txais, cuam tshuam nrog mob qog nqaij hlav hauv pancreatic. Nws muaj qee yam kev pheej hmoo rau mob qog nqaij hlav cancer, txawm hais tias muaj ib qho tsis txhais tau tias koj yuav mob qog nqaij hlav hauv pancreatic. Tham nrog koj tus kws kho mob txog koj qib kev pheej hmoo.
Cov mob muaj feem raug raws caj ces yog:
- ataxia telangiectasia, tshwm sim los ntawm cov kev sib hloov hauv cov noob ATM
- mob nqaij hlav rau (lossis muaj keeb kwm) pancreatitis, feem ntau yog vim muaj kev sib faib hauv lub PRSS1 gene
- tsev neeg adenomatous polyposis, tshwm sim los ntawm cov tsis zoo APC gene
- txheeb ze atypical ntau mole melanoma syndrome, vim muaj kev hloov pauv hauv p16 / CDKN2A noob
- mob muaj keeb mob mis thiab mob cancer ntawm zes qe menyuam, tshwm sim los ntawm BRCA1 thiab BRCA2 hloov pauv noob
- Li-Fraumeni syndrome, qhov tshwm sim ntawm kev tsis sib haum xeeb hauv p53 gene
- Lynch mob (mob qa tsis mob hlwb txha caj qaum mob qog nqaij hlav cancer), feem ntau tshwm sim los ntawm cov tsis xws luag MLH1 lossis MSH2 noob
- ntau tus kab mob endocrine neoplasia, hom 1, tshwm sim los ntawm ib tug faulty MEN1 noob
- neurofibromatosis, hom 1, vim muaj kev hloov pauv hauv NF1 noob
- Peutz-Jeghers mob ntsws, tshwm sim los ntawm kev tsis txaus ntseeg hauv tus lej STK11
- Von Hippel-Lindau syndrome, qhov tshwm sim ntawm kev sib faib me me hauv VHL noob
“Mob cancer rau lub cev” txiav txim siab txhais tau tias nws khiav hauv ib tsev neeg qhov twg:
- Tsawg kawg yog ob tus neeg txheeb ze thawj (niam txiv, nus muag, lossis menyuam) tau mob qog nqaij hlav
- Muaj peb lossis ntau tus neeg txheeb ze nrog mob qog nqaij hlav hauv tib lub tsev neeg.
- Muaj ib tus mob khees xaws hauv tsev neeg ntxiv rau tsawg kawg ib tus neeg hauv tsev neeg muaj mob qog nqaij hlav cancer.
Lwm yam mob uas tuaj yeem ua rau muaj feem mob qog nqaij hlav cancer yog:
- mob txha taub hau
- cirrhosis ntawm daim siab
- Helicobacter pylori (H. pylori) kev kis mob
- ntshav qab zib hom 2
Lwm yam kev pheej hmoo muaj xws li:
- Lub hnub nyoog. Ntau dua 80 feem pua ntawm cov kab mob pancreatic mob hlav rau cov neeg muaj hnub nyoog 60 txog 80 xyoo.
- Tub los ntxhais. Tus txiv neej muaj kev pheej hmoo siab dua li poj niam.
- Kwv Txhiaj. Cov neeg African-Americans muaj feem ntau dua li Caucasians.
Yam tseem ceeb ntawm kev ua neej kuj tseem tuaj yeem ua rau muaj kev pheej hmoo ntawm mob qog nqaij hlav. Piv txwv li:
- Haus Yeeb luam yeeb ntau koj txoj kev pheej hmoo ntawm kev tsim mob qog noj qab zib. Cigars, kav dej, thiab cov pa luam yeeb uas tsis haus luam yeeb kuj ua rau koj muaj kev pheej hmoo.
- Kev pham tsa cov kev pheej hmoo ntawm tus mob cancer rau txiav 20 feem pua.
- Hnyav kis tau cov tshuaj siv hauv kev siv hlau ua haujlwm thiab kev ua haujlwm qhuav-huv tuaj yeem ua rau koj qhov kev pheej hmoo.
Kab mob qog ntshav yog mob ntau npaum li cas?
Nws yog hom mob qog tsawg. Li ntawm 1.6 feem pua ntawm tib neeg yuav mob qog nqaij hlav hauv pancreatic hauv lawv lub neej.
Cov tsos mob los saib rau
Feem ntau, cov tsos mob tsis pom tseeb thaum ntxov pom tias muaj kabmob khees xaws.
Raws li cov kabmob nce qib, cov cim thiab cov tsos mob yuav suav nrog:
- mob hauv koj sab plab, tej zaum tawg rau koj sab nraum qab
- tsis qab los noj mov
- poob phaus
- nkees
- daj tawv nqaij thiab qhov muag (daj)
- tshiab pib ntshav qab zib
- kev nyuaj siab
Thaum twg mus ntsib koj tus kws kho mob
Yeej tsis muaj kev sim tshuaj rau cov tib neeg muaj feem yuav muaj mob qog nqaij hlav cancer.
Tej zaum koj yuav muaj kev pheej hmoo siab ntau yog tias koj muaj keeb kwm tsev neeg mob qog nqaij hlav cancer (pancreatic) lossis muaj mob ua rau mob ua tsis muaj qab hau. Yog li ntawv, koj tus kws kho mob yuav hais kom kuaj ntshav mus kuaj seb puas muaj cov noob cuam tshuam nrog mob qog noj ntshav.
Cov kev kuaj no tuaj yeem qhia koj yog tias koj muaj kev hloov, tab sis tsis yog tias koj muaj mob qog nqaij hlav hauv pancreatic. Ib qho ntxiv, kev hloov pauv ntawm cov noob tsis txhais tau tias koj yuav muaj mob qog nqaij hlav hauv pancreatic.
Txawm hais tias koj nyob hauv nruab nrab lossis pheej hmoo pheej hmoo, cov tsos mob xws li mob plab thiab yuag poob txhais tau tias koj tsis muaj mob qog nqaij hlav pancreatic. Cov no tuaj yeem ua pov thawj ntawm ntau yam mob, tab sis nws yog ib qho tseem ceeb kom ntsib koj tus kws kho mob rau kev kuaj mob. Yog tias koj muaj cov tsos mob daj ntseg, mus ntsib koj tus kws kho mob sai li sai tau.
Dab tsi tshwm sim los ntawm kev kuaj pom
Koj tus kws kho mob yuav xav ua keeb kwm kev kho mob kom zoo.
Tom qab kuaj lub cev, kev kuaj mob tuaj yeem suav nrog:
- Kev ntsuam xyuas cov duab. Cov duab thaij sab qaum kev kuaj pom, thaij duab CT, MRI, thiab tus tsiaj PET tuaj yeem siv los tsim cov duab kom ntxaws los saib rau kev ua txhaum ntawm koj lub cev thiab lwm yam hauv nruab nrog cev.
- Endoscopic ultrasound. Nyob hauv txoj kev ua no, ib txoj hlab nyias nyias, yoog (endoscope) kis hauv koj txoj hlab pas thiab hauv koj lub plab mus saib koj lub txiav.
- Raug me. Tus kws kho mob yuav ntxiv ib rab koob nyias nyias hauv koj lub plab thiab nkag rau hauv lub qhov quav kom tau cov qauv ntawm daim ntaub uas neeg xoos xaim. Tus kws khomob tseem yuav kuaj cov kab mob hauv qab lub tshuab tsom seb puas muaj cov qog nqaij hlav.
Koj tus kws kho mob tuaj yeem kuaj koj cov ntshav rau cov cim qog uas cuam tshuam nrog kev mob qog noj ntshav. Tab sis qhov kev ntsuas no tsis yog ib qho kev paub siv uas ntseeg tau; feem ntau yog siv los ntsuas seb cov kev kho mob ua haujlwm li cas.
Muaj dab tsi tshwm sim txuas ntxiv?
Tom qab kuaj pom, tus mob qog yuav tsum ua kom raws li nws kis tau mus ntev npaum li cas. Kev mob kheesxaws hauv Pancreatic yog ib theem los ntawm 0 txog 4, nrog 4 yog tus tshaj plaws. Qhov no pab txiav txim siab txog koj cov kev kho mob, uas tej zaum suav nrog kev phais mob, kho hluav taws xob, thiab siv tshuaj kho mob.
Txog kev kho mob hom kab mob qog nqaij hlav cancer kuj tuaj yeem ua raws li:
- Resableable. Nws pom tias cov qog yuav phais tau nws txoj kev hloov siab.
- Ciaj ciam kev rov ua haujlwm. Mob khees xaws tau mus txog rau cov ntshav nyob ze, tab sis nws yog tuaj yeem ua rau tus kws phais neeg tuaj yeem tshem nws tag.
- Kev tshawb tsis taus. Nws tshem tawm tsis tau tag hauv kev phais.
Koj tus kws kho mob yuav txiav txim qhov no, nrog rau koj cov ntaub ntawv kho mob tiav, txhawm rau pab txiav txim siab txog kev kho mob zoo tshaj plaws rau koj.